[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Beykoz University\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":200},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,6,0,[8,53,82,117,148,175],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":33,"overallStatus":40,"whyStopped":4,"lastUpdateSubmitDate":41,"lastUpdatePostDateStruct":42,"startDateStruct":45,"completionDateStruct":47,"leadSponsor":49,"locationsCount":52},"100600704","comparing-brief-psychoanalytic-couple-therapy-and-emotionally-focused-therapy-in-reducing-relationship-distress-100600704",false,"NCT07100951","Comparing Brief Psychoanalytic Couple Therapy and Emotionally Focused Therapy in Reducing Relationship Distress","Comparing the Efficacy of Brief Psychoanalytic Couple Therapy and Emotionally Focused Therapy in Reducing Relationship Distress and Psychopathological Symptoms: A Randomized Controlled Trial","BPCT-EFT-RCT","Inclusion Criteria:\n\n* Heterosexual couples (both partners must participate)\n* Age between 24 and 65 years\n* Minimum 2 years of relationship duration\n* At least one partner scoring ≤ 30 on the Dyadic Adjustment Scale (DAS-32), indicating clinically significant relationship distress\n* At least one partner scoring in the mild, moderate, or severe range on the Beck Depression Inventory-II (BDI-II) or Beck Anxiety Inventory (BAI)\n\nExclusion Criteria:\n\n* Current participation in individual or couple psychotherapy\n* Use of psychiatric medication during the past 3 months\n* Presence of severe psychiatric disorders (e.g., psychosis, bipolar disorder)\n* History or presence of physical or severe psychological partner violence, assessed via Conflict Tactics Scale (CTS-2)\n* Active substance use disorder within the past 6 months","ALL","24 Years","65 Years",{"count":21,"type":22},120,"ESTIMATED","INTERVENTIONAL",[25],"NA","This study compares the effects of two different couple therapy approaches-Brief Psychoanalytic Couple Therapy (BPCT) and Emotionally Focused Therapy (EFT)-on reducing relationship problems and emotional symptoms like depression and anxiety.\n\nMany couples struggle with emotional distance, repeated arguments, and dissatisfaction in their relationships. While EFT is a widely used and research-supported therapy that focuses on rebuilding emotional bonds, BPCT is a less-studied method that aims to help couples understand how early relationship experiences and unconscious patterns affect their current interactions.\n\nThe purpose of this study is to find out whether one of these therapies is more effective than the other in improving relationship satisfaction and reducing emotional distress. The study also looks at changes in how people regulate their emotions and how secure they feel in their relationships after therapy.\n\nIn this randomized controlled trial, 60 heterosexual couples experiencing relationship distress and symptoms of anxiety or depression will be randomly assigned to one of three groups:\n\nBPCT group - couples receive weekly online therapy focusing on deep emotional and psychological patterns in their relationship.\n\nEFT group - couples receive weekly online therapy focusing on emotional connection and improving communication.\n\nWaitlist control group - couples do not receive therapy during the study but will be offered therapy afterward.\n\nEach therapy lasts 12 weeks, and follow-up assessments will be conducted up to 6 months after therapy ends. Data will be collected before, during, and after treatment using questionnaires that measure relationship satisfaction, depression, anxiety, emotional regulation, and attachment style.\n\nThe results of this study will help determine which type of therapy is more beneficial for couples experiencing emotional and relational difficulties and may provide important insights for mental health professionals working with distressed couples.",[28,29,30,31,32],"Depressive Disorder","Anxiety Disorders","Emotion Regulation","Attachment","Relationship Distress",[34,35,36,37,32,30,38,39],"Brief Psychoanalytic Couple Therapy","Emotionally Focused Therapy","Couple Therapy","Online Psychotherapy","Depression","Anxiety","RECRUITING","2025-07-28",{"date":43,"type":44},"2025-08-03","ACTUAL",{"date":46,"type":44},"2025-07-01",{"date":48,"type":22},"2026-07-15",{"name":50,"class":51},"Beykoz University","OTHER",1,{"id":54,"slug":55,"hasResults":11,"nctId":56,"briefTitle":57,"officialTitle":58,"acronym":4,"eligibilityCriteria":59,"healthyVolunteers":60,"sex":17,"minAge":61,"maxAge":19,"enrollmentInfo":62,"targetDuration":4,"studyType":23,"phases":64,"briefSummary":65,"conditions":66,"keywords":69,"overallStatus":40,"whyStopped":4,"lastUpdateSubmitDate":74,"lastUpdatePostDateStruct":75,"startDateStruct":77,"completionDateStruct":79,"leadSponsor":81,"locationsCount":52},"100596054","child-parent-psychotherapy-after-the-2023-kahramanmara-earthquake-100596054","NCT07040462","Child-Parent Psychotherapy After the 2023 Kahramanmaraş Earthquake","Child-Parent Psychotherapy for Post-Earthquake Trauma in Preschool Children: A Randomized Controlled Trial","Inclusion Criteria:\n\n* Children aged 3 to 6 years old at the time of enrollment\n* Resided in one of the 11 cities affected by the 2023 Kahramanmaraş earthquake (e.g., Hatay, Kahramanmaraş, Adıyaman, Malatya, Gaziantep, Şanlıurfa, Adana, Osmaniye, Diyarbakır, Kilis, Elazığ)\n* Exposure to at least one qualifying traumatic event due to the earthquake (e.g., witnessing injury or death, loss of home, separation from caregiver)\n* Living with a primary caregiver (mother or father) who consents to participate in the study\n* Both caregiver and child are available to participate in 12 weekly sessions of CPP (online or face-to-face)\n* Caregiver is fluent in Turkish and able to complete self-report questionnaires\n\nExclusion Criteria:\n\n* Child or caregiver currently receiving psychotherapy or psychiatric treatment\n* Child diagnosed with developmental disorder (e.g., autism, intellectual disability) that significantly impairs communication or relational functioning\n* Caregiver with a diagnosed severe psychiatric disorder (e.g., psychosis, bipolar disorder) or active substance use disorder\n* Families with ongoing legal custody disputes or instability that may interfere with consistent participation\n* Inability to access internet or digital device (for participants randomized to online therapy)",true,"3 Years",{"count":63,"type":22},60,[25],"This study aims to evaluate the effectiveness of Child-Parent Psychotherapy (CPP) in reducing trauma-related symptoms and improving attachment quality among preschool-aged children who experienced the 2023 Kahramanmaraş earthquakes in Türkiye. A total of 60 caregiver-child dyads (children aged 3-6) will be recruited from 11 earthquake-affected provinces. Participants will be randomly assigned to either the intervention group, receiving 12 weekly CPP sessions, or a no-intervention control group. CPP will be delivered by trained clinical psychologists through either online or face-to-face sessions. Assessments will be conducted at baseline, mid-intervention (after session 6), and post-intervention (after session 12). Outcomes include child trauma symptoms, social-emotional functioning, and attachment quality, as well as caregiver reflective functioning, stress, and emotional well-being.",[67,68],"Post-Traumatic Stress Disorder Complex","Emotional Dysregulation",[70,71,72,73],"Child-Parent Psychotherapy (CPP)","Trauma Therapy","Preschool Children","Kahramanmaraş Earthquake","2025-06-18",{"date":76,"type":44},"2025-06-27",{"date":78,"type":44},"2025-06-15",{"date":80,"type":22},"2025-11-15",{"name":50,"class":51},{"id":83,"slug":84,"hasResults":11,"nctId":85,"briefTitle":86,"officialTitle":87,"acronym":88,"eligibilityCriteria":89,"healthyVolunteers":60,"sex":17,"minAge":90,"maxAge":91,"enrollmentInfo":92,"targetDuration":4,"studyType":23,"phases":93,"briefSummary":94,"conditions":95,"keywords":99,"overallStatus":40,"whyStopped":4,"lastUpdateSubmitDate":109,"lastUpdatePostDateStruct":110,"startDateStruct":112,"completionDateStruct":114,"leadSponsor":116,"locationsCount":52},"100588054","cognitive-remediation-therapy-for-schizophrenia-effects-on-eeg-and-emotional-regulation-100588054","NCT06936397","Cognitive Remediation Therapy for Schizophrenia: Effects on EEG and Emotional Regulation","A Randomized Controlled EEG-GSR Study on the Effects of Cognitive Remediation Therapy on Neurophysiological and Emotional Regulation Markers in Schizophrenia","CRT-SCHZ","Inclusion Criteria (Schizophrenia Group):\n\n* Diagnosed with schizophrenia according to DSM-5 criteria\n* Age between 18 and 55 years\n* Clinically stable (no hospitalization or medication change within 1 month)\n* Minimum primary school education\n* Able to provide informed consent\n* Right-handed (for EEG protocol consistency)\n\nInclusion Criteria (Healthy Control Group):\n\n* No history of psychiatric or neurological disorders\n* Age- and gender-matched to schizophrenia group\n* No current medication affecting CNS\n* Able to provide informed consent\n* Right-handed\n\nExclusion Criteria (Both Groups):\n\n* Current or past substance use disorder (within the past year)\n* Comorbid neurological illness (e.g., epilepsy, traumatic brain injury)\n* Current use of benzodiazepines or medications that significantly affect cognitive function\n* Intellectual disability or MoCA score \\\u003C 20\n* Visual or hearing impairments that could interfere with task performance\n* Participation in a psychological intervention in the last 3 months","18 Years","55 Years",{"count":63,"type":22},[25],"This study aims to determine whether Cognitive Remediation Therapy (CRT) can improve attention, memory, and emotional regulation in people with schizophrenia. CRT is a structured program that includes exercises to strengthen cognitive skills such as problem-solving, working memory, and emotion regulation.\n\nThe study will recruit 60 participants: 30 individuals with schizophrenia and 30 healthy individuals of similar age and gender. Those with schizophrenia will be randomly assigned to either receive CRT or be placed on a waitlist without therapy. All participants will undergo non-invasive brain activity (EEG) and emotional response (GSR) recordings before and after the therapy.\n\nThe study's main question is: Does participating in a 12-week CRT program improve brain-based markers of attention and emotional regulation in people with schizophrenia?\n\nAdditional tests, such as memory and emotion recognition tasks and self-report questionnaires, will help assess changes in thinking skills and emotional well-being. The study may help better understand how CRT affects both brain function and quality of life in schizophrenia.",[96,97,98],"Schizophrenia Disorders","Cognitive Dysfunction","Emotion Regulation Disorders",[100,101,102,103,30,104,105,106,107,108],"Cognitive Remediation Therapy","Schizophrenia","EEG","GSR","Executive Function","P300","Mismatch Negativity","Neurophysiological Biomarkers","Psychophysiology","2025-04-13",{"date":111,"type":44},"2025-04-20",{"date":113,"type":44},"2025-03-15",{"date":115,"type":22},"2025-10-15",{"name":50,"class":51},{"id":118,"slug":119,"hasResults":11,"nctId":120,"briefTitle":121,"officialTitle":122,"acronym":4,"eligibilityCriteria":123,"healthyVolunteers":11,"sex":17,"minAge":90,"maxAge":19,"enrollmentInfo":124,"targetDuration":4,"studyType":23,"phases":126,"briefSummary":127,"conditions":128,"keywords":132,"overallStatus":40,"whyStopped":4,"lastUpdateSubmitDate":109,"lastUpdatePostDateStruct":141,"startDateStruct":143,"completionDateStruct":145,"leadSponsor":147,"locationsCount":52},"100586544","comparing-combined-behavioral-intervention-and-ericksonian-hypnotherapy-for-alcohol-addiction-100586544","NCT06916754","Comparing Combined Behavioral Intervention and Ericksonian Hypnotherapy for Alcohol Addiction","Comparing the Efficacy of Combined Behavioral Intervention and Ericksonian Hypnotherapy in the Treatment of Alcohol Addiction: A Randomized Controlled Trial","Inclusion Criteria:\n\n* Aged between 18 and 65 years\n* Meets DSM-5 diagnostic criteria for Alcohol Use Disorder (mild to severe)\n* Medically and psychiatrically stable as determined by a clinician\n* Willing and able to participate in weekly sessions over a 12-week period\n* Provides informed consent\n\nExclusion Criteria:\n\n* Current diagnosis of a severe psychiatric disorder (e.g., psychotic disorder, bipolar I disorder)\n* Significant cognitive impairment that would interfere with treatment participation\n* Participation in another structured addiction treatment during the study period\n* Current use of psychotropic medications that may influence outcome measures (as assessed by the clinical team)\n* Unstable medical condition requiring immediate intervention\n* Pregnancy or planning to become pregnant during the study period",{"count":125,"type":22},90,[25],"This clinical study is being conducted to compare the effectiveness of two psychological treatments for alcohol addiction: Combined Behavioral Intervention (CBI) and Ericksonian Hypnotherapy (EH). The purpose of the study is to determine whether Ericksonian Hypnotherapy, a more personalized and indirect therapeutic method, is equal to or more effective than the gold-standard approach, Combined Behavioral Intervention, in helping individuals reduce their alcohol consumption and improve psychological well-being.\n\nAlcohol addiction is a serious condition that affects mental, emotional, and physical health. Many treatment options exist, but not all individuals respond in the same way. This study aims to evaluate two different types of therapy in a structured way, to better understand which works best, for whom, and under what circumstances.\n\nThe study will include 90 adult participants diagnosed with Alcohol Use Disorder (AUD). Participants will be randomly assigned to one of three groups: (1) a group receiving weekly sessions of Combined Behavioral Intervention, (2) a group receiving weekly sessions of Ericksonian Hypnotherapy, or (3) a control group receiving general educational materials about alcohol addiction. Treatment will last for 12 weeks, and all participants will be followed up three months after the last session to assess long-term effects.\n\nThroughout the study, researchers will measure changes in alcohol consumption, alcohol craving, mental health symptoms (such as depression and anxiety), quality of life, and motivation to change. The findings of this study may help improve the way alcohol addiction is treated by offering evidence on alternative approaches such as hypnotherapy.",[129,130,131],"Alcohol-Related Disorders","Alcoholism","Substance-related Disorders",[133,134,135,136,137,138,139,140],"Ericksonian Hypnosis","Hypnotherapy","Cognitive Behavioral Therapy","Motivational Interviewing","Relapse Prevention","Craving","Substance Craving","Psychotherapy",{"date":142,"type":44},"2025-04-16",{"date":144,"type":44},"2025-03-01",{"date":146,"type":22},"2026-02-01",{"name":50,"class":51},{"id":149,"slug":150,"hasResults":11,"nctId":151,"briefTitle":152,"officialTitle":153,"acronym":154,"eligibilityCriteria":155,"healthyVolunteers":60,"sex":17,"minAge":90,"maxAge":19,"enrollmentInfo":156,"targetDuration":4,"studyType":23,"phases":158,"briefSummary":159,"conditions":160,"keywords":162,"overallStatus":40,"whyStopped":4,"lastUpdateSubmitDate":167,"lastUpdatePostDateStruct":168,"startDateStruct":170,"completionDateStruct":172,"leadSponsor":174,"locationsCount":52},"100584689","efct-vs-bct-for-depression-and-anxiety-in-married-couples-100584689","NCT06892613","EFCT vs. BCT for Depression and Anxiety in Married Couples","A Comparison of the Effectiveness of Emotion-Focused Couples Therapy and Behavioral Couples Therapy in Reducing Depression and Anxiety Symptoms in Married Couples","EFCT-BCT","Inclusion Criteria:\n\n* Married couples aged between 18 and 65 years\n* Married for at least one year\n* No current psychiatric diagnosis or history of psychiatric treatment\n* Not receiving any form of psychological therapy at the time of recruitment\n* Ability to provide informed consent\n* Willingness to participate in all therapy sessions and assessments\n\nExclusion Criteria:\n\n* Current or past psychiatric diagnosis (excluding mild transient conditions)\n* Ongoing psychological therapy or psychiatric treatment\n* Severe mental health disorders (e.g., schizophrenia, bipolar disorder), Substance abuse or dependency\n* Severe medical conditions that may interfere with participation\n* Refusal to participate in follow-up assessments",{"count":157,"type":22},150,[25],"This study compares the effectiveness of Emotion-Focused Couples Therapy (EFCT) and Behavioral Couples Therapy (BCT) in reducing depression and anxiety symptoms in married couples. A total of 150 married couples aged 18-65 will be screened, and 60 couples with high depression and anxiety levels will be selected. These couples will be randomly assigned to one of three groups: EFCT, BCT, or a control group. Therapy sessions will be conducted weekly for 12 weeks, with assessments before therapy, after the 6th and 12th sessions, and at a 3-month follow-up. The study aims to determine which therapy is more effective in improving mental health outcomes in couples.",[161,39],"Depression Anxiety Disorder",[38,39,163,164,165,140,166],"Emotion-Focused Couples Therapy","Behavioral Couples Therapy","Mental Health","Marital Counseling","2025-03-21",{"date":169,"type":44},"2025-03-25",{"date":171,"type":44},"2025-01-01",{"date":173,"type":22},"2025-09-15",{"name":50,"class":51},{"id":176,"slug":177,"hasResults":11,"nctId":178,"briefTitle":179,"officialTitle":180,"acronym":181,"eligibilityCriteria":182,"healthyVolunteers":11,"sex":17,"minAge":90,"maxAge":19,"enrollmentInfo":183,"targetDuration":4,"studyType":23,"phases":184,"briefSummary":185,"conditions":186,"keywords":188,"overallStatus":40,"whyStopped":4,"lastUpdateSubmitDate":192,"lastUpdatePostDateStruct":193,"startDateStruct":195,"completionDateStruct":197,"leadSponsor":199,"locationsCount":52},"100580008","rct-of-short-term-psychoanalytic-vs-cognitive-behavioral-therapy-for-gad-100580008","NCT06831708","RCT of Short-Term Psychoanalytic vs. Cognitive Behavioral Therapy for GAD","A Randomized Controlled Trial Comparing Short-Term Psychoanalytic Therapy and Cognitive Behavioral Therapy for Generalized Anxiety Disorder","(RCT-GAD)","Inclusion Criteria:\n\n* Age between 18 and 65 years.\n* A confirmed diagnosis of Generalized Anxiety Disorder (GAD) according to DSM-5 criteria, with the diagnosis made within the past 2 years.\n* No participation in any form of psychotherapy during the past 6 months.\n* Ability and willingness to attend 12 weekly therapy sessions (50 minutes each) over the 3-month intervention period.\n* For participants receiving online sessions: access to a stable internet connection and the necessary technology.\n* Ability to understand and provide written informed consent.\n\nExclusion Criteria:\n\n* Presence of significant comorbid psychiatric disorders that could interfere with participation or assessment (e.g., bipolar disorder, psychotic disorders, substance use disorders, eating disorders).\n* Recent changes in psychotropic medication (i.e., medication changes within the past 3 months, unless on a stable dose).\n* Severe medical or neurological conditions that may interfere with study participation or data interpretation.\n* Current participation in another clinical trial or structured psychotherapy program.\n* Any condition that, in the opinion of the investigators, would compromise the safety or compliance of the participant in the study.",{"count":63,"type":22},[25],"This study is a randomized controlled trial designed to compare the effectiveness of two types of short-term psychotherapy-psychoanalytic therapy and Cognitive Behavioral Therapy (CBT)-in treating Generalized Anxiety Disorder (GAD). A total of 60 adult participants with a confirmed diagnosis of GAD will be enrolled and randomly assigned to one of three groups: one group will receive psychoanalytic therapy, a second group will receive CBT, and a third group will serve as a control (waiting list) group. Each treatment group will participate in 12 weekly sessions, with each session lasting 50 minutes.\n\nIn the psychoanalytic therapy group, therapy will follow a standardized framework based on core psychoanalytic principles such as exploring unconscious conflicts, transference, and resistance. While this approach is flexible, all therapists will be trained and calibrated to apply these core principles consistently. In contrast, the Cognitive Behavioral Therapy (CBT) group will receive a structured, manualized intervention specifically designed for Generalized Anxiety Disorder (GAD). The control group will not receive any active psychotherapy during the study period but will continue to receive any standard care they are already using.\n\nThe primary outcome of the study will be the change in anxiety symptoms measured by the Beck Anxiety Inventory (BAI) from before treatment to after the 12 sessions. Secondary outcomes will include measures of quality of life (using the World Health Organization Quality of Life Instrument \\[WHOQOL-BREF\\]), depressive symptoms (using the Beck Depression Inventory-II \\[BDI-II\\]), functional impairment (using the World Health Organization Disability Assessment Schedule II \\[WHODAS II\\]), the quality of the therapeutic relationship (using the Working Alliance Inventory \\[WAI\\]), and overall treatment satisfaction.\n\nThe study is designed to be completed within a six-month period: one month for recruitment, one month for baseline assessments and clinical checks, and three months for the intervention. Data will be collected at baseline and immediately after the intervention, with the goal of analyzing and publishing the results as soon as possible following treatment completion. This study has received ethical approval from the Üsküdar University Ethics Committee and is intended to inform future research on effective treatments for Generalized Anxiety Disorder (GAD).",[187],"Generalized Anxiety Disorder",[187,189,135,190,39,191],"Psychoanalytic Therapy","RCT","Short-Term Psychotherapy","2025-02-16",{"date":194,"type":44},"2025-02-18",{"date":196,"type":44},"2025-02-01",{"date":198,"type":22},"2025-09-01",{"name":50,"class":51},""]