[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Biao Zou\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":95},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,48,74],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":17,"sex":18,"minAge":19,"maxAge":20,"enrollmentInfo":21,"targetDuration":4,"studyType":24,"phases":25,"briefSummary":27,"conditions":28,"keywords":30,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":36,"lastUpdatePostDateStruct":37,"startDateStruct":40,"completionDateStruct":42,"leadSponsor":44,"locationsCount":47},"100497171","effect-of-fecal-microbiota-transplantation-fmt-in-pediatric-functional-gastrointestinal-disorders-100497171",false,"NCT05753774","Effect of Fecal Microbiota Transplantation (FMT) in Pediatric Functional Gastrointestinal Disorders","Efficacy and Safety of Fecal Microbiota Transplantation in the Treatment of Functional Gastrointestinal Disorders in Children","FGIDs","Inclusion Criteria:\n\n* The diagnosis and classification of patients with FGIDs were in accordance with the ROME IV criteria for children\n\nExclusion Criteria:\n\n* organic gastrointestinal disease (as established by medical history, blood routine, biochemistry, c-reaction protein, erythrocyte sedimentation rate, and fecal routine examinations.)\n* other chronic disease\n* growth failure",true,"ALL","1 Year","15 Years",{"count":22,"type":23},100,"ESTIMATED","INTERVENTIONAL",[26],"NA","Safety and efficacy of FMT in Pediatric Functional Gastrointestinal Disorders",[29],"Functional Gastrointestinal Disorders",[31,32,33,34],"Functional Gastrointestinal Disorders;","FMT;","Safety; efficacy","efficacy","RECRUITING","2025-09-03",{"date":38,"type":39},"2025-09-10","ACTUAL",{"date":41,"type":39},"2022-08-01",{"date":43,"type":23},"2026-08-01",{"name":45,"class":46},"Biao Zou","OTHER",1,{"id":49,"slug":50,"hasResults":11,"nctId":51,"briefTitle":52,"officialTitle":53,"acronym":54,"eligibilityCriteria":55,"healthyVolunteers":17,"sex":18,"minAge":56,"maxAge":57,"enrollmentInfo":58,"targetDuration":4,"studyType":24,"phases":60,"briefSummary":61,"conditions":62,"keywords":64,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":66,"lastUpdatePostDateStruct":67,"startDateStruct":69,"completionDateStruct":71,"leadSponsor":73,"locationsCount":47},"100491476","fecal-microbiota-transplantation-in-pediatric-ulcerative-colitis-uc-100491476","NCT05679622","Fecal Microbiota Transplantation in Pediatric Ulcerative Colitis (UC)","Repeated and Multiple Fecal Microbiota Transplantations in Active Pediatric Ulcerative Colitis (UC)","FMT","Inclusion Criteria:\n\nage of older than 2 years and younger than 16 years with no genetic diseases; as a first-line treatment group for UC, newly diagnosed with mild-to-moderate UC (defined by the PUCAI of \\>10 and≤64); In the refractory ulcerative colitis group, all refractory pediatric with mild-to-moderate UC (defined by the PUCAI of \\>10 and≤64) defined by children who failed conventional treatment (hormone, immunosuppressant, biologics); agree to received regularly colonoscopy\n\nExclusion Criteria:\n\nChildren who were treated by PEN (80%) less than 8 weeks; As a first-line treatment group for UC, patients who were treated with corticosteroids, methotrexate, thiopurines, and anti-TNF agents as their first-line treatment; Known contraindication to all FMT infusion method such as nasoduodenal tube insertion, oesophago-gastro-duodenoscopy (OGD), enteroscopy, colonoscopy, enema and Fecal capsule; Unwilling to give informed consent\u002F assent","2 Years","16 Years",{"count":59,"type":23},30,[26],"This study included two topics: one was to test the efficacy and safety of fecal microbiota transplants plus partial enteral nutrition (PEN) in refractory pediatric UC where conventional therapy has failed, and the other was to explore the efficacy and safety of FMT plus PEN as first-line therapy for pediatric active UC",[63],"Ulcerative Colitis",[65],"Fecal microbiota transplantation, Ulcerative Colitis","2024-11-01",{"date":68,"type":39},"2024-11-04",{"date":70,"type":39},"2022-12-01",{"date":72,"type":23},"2025-06-30",{"name":45,"class":46},{"id":75,"slug":76,"hasResults":11,"nctId":77,"briefTitle":78,"officialTitle":79,"acronym":54,"eligibilityCriteria":80,"healthyVolunteers":11,"sex":18,"minAge":56,"maxAge":57,"enrollmentInfo":81,"targetDuration":4,"studyType":24,"phases":83,"briefSummary":84,"conditions":85,"keywords":87,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":66,"lastUpdatePostDateStruct":89,"startDateStruct":90,"completionDateStruct":92,"leadSponsor":94,"locationsCount":47},"100463980","fecal-microbiota-transplantation-in-pediatric-crohns-disease-100463980","NCT05321745","Fecal Microbiota Transplantation in Pediatric Crohn's Disease","Repeated and Periodic Fecal Microbiota Transplantation in Children With Active and Refractory Crohn's Disease","Inclusion Criteria:\n\nAged 2-16 years and without genetic diseases; All refractory pediatric with mild-to-moderate CD; Mild-to-moderate CD, defined by the pediatric Crohn's disease activity index (PCDAI) \\>10 and ≤40 and Simple Endoscopic Score for CD (SES-CD) \\> 3 were enrolled in the study; refractory CD, defined by children who failed conventional treatment (hormone, immunosuppressant, biologics)\n\nExclusion Criteria Children who were treated by PEN (80%) less than 8 weeks; follow up less than 3 months; known contraindication to all FMT infusion method such as nasoduodenal tube insertion, oesophago-gastro-duodenoscopy (OGD), enteroscopy, colonoscopy, enema and Fecal capsule; unwilling to give informed consent\u002Fassent",{"count":82,"type":23},40,[26],"This study will test the safety and effectiveness of fecal microbiota transplantation (FMT) plus partial enteral nutrition (PEN) in refractory pediatric Crohn's disease (CD) who have failed conventional treatment",[86],"Crohn Disease",[88],"fecal microbiota transplantation , Crohn Disease",{"date":68,"type":39},{"date":91,"type":39},"2022-03-22",{"date":93,"type":23},"2026-05-31",{"name":45,"class":46},""]