[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Bioaster\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":77},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,50],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":14,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":31,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":38,"lastUpdatePostDateStruct":39,"startDateStruct":42,"completionDateStruct":44,"leadSponsor":46,"locationsCount":49},"100543052","development-of-a-new-rapid-diagnostic-test-to-support-onchocerciasis-elimination-100543052",false,"NCT06350851","Development of a New Rapid Diagnostic Test to Support Onchocerciasis Elimination","Obi1","Inclusion Criteria:\n\n* Subjects informed of the objectives of the study and who signed a consent form\n* Subjects without filariasis (for control subjects), or\n* Subjects mono-infected with Onchocerca volvulus, or\n* Subjects mono-infected with Loa loa, or\n* Subjects mono-infected with Mansonella perstans or alternatively co-infected with Mansonella perstans and Loa loa\n\nExclusion Criteria:\n\n* Pregnant or breast-feeding women\n* Subjects having taken antihelminthic treatment less than 6 months before the inclusion date",true,"ALL","18 Years",{"count":20,"type":21},400,"ESTIMATED","INTERVENTIONAL",[24],"NA","Onchocerciasis, also known as river blindness, is one of the disease targeted for elimination by the World Health Organization (WHO) in the group of Neglected Tropical Diseases. Existing diagnostic tools for onchocerciasis have limitations that make mapping, epidemiological assessments and verification of elimination of onchocerciasis difficult. It is in this context that WHO, in its 2021-2030 roadmap for onchocerciasis, has identified the development of new diagnostic tests, or the improvement of existing diagnostic tests, as a critical condition for achieving the goal of eliminating onchocerciasis transmission.\n\nTo this end, a series of cross-sectional studies will be carried out in Cameroun over a one year period to collect and characterize biological samples for the development and evaluation of a new rapid diagnostic test for onchocerciasis. The study will target individuals aged 18 and over, mono-infected with one of the filarial species Onchocerca volvulus, Loa loa or Mansonella perstans; and non-infected.\n\nAt the end of this study, data on the endemicity of onchocerciasis, loiasis and mansonellosis in the selected communities will be updated. More importantly, a new rapid diagnostic test will be developed, which can then be used to monitor the activities of onchocerciasis control programs.",[27,28,29,30],"Onchocerciasis","Loiasis","Mansonelliasis","Healthy Volunteers",[32,33,34,35,36],"Onchocerca volvulus","Loa loa","Mansonella perstans","Biplex Rapid Diagnostic Test","Neglected Tropical Diseases","RECRUITING","2025-03-05",{"date":40,"type":41},"2025-03-07","ACTUAL",{"date":43,"type":41},"2024-04-15",{"date":45,"type":21},"2025-12",{"name":47,"class":48},"Bioaster","OTHER",1,{"id":51,"slug":52,"hasResults":11,"nctId":53,"briefTitle":54,"officialTitle":55,"acronym":56,"eligibilityCriteria":57,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":58,"targetDuration":4,"studyType":60,"phases":4,"briefSummary":61,"conditions":62,"keywords":64,"overallStatus":68,"whyStopped":4,"lastUpdateSubmitDate":69,"lastUpdatePostDateStruct":70,"startDateStruct":72,"completionDateStruct":74,"leadSponsor":76,"locationsCount":4},"100562378","human-internal-bioasters-samples-collection-100562378","NCT06602388","Human Internal BIOASTER's Samples Collection","Non-interventional, Monocentric Study Aimed at Building up a Collection of Biological Samples Collected From Bioaster Collaborators for Scientific Purposes","HIBISCUS","Inclusion Criteria:\n\nSome inclusion criteria can be defined according to the needs of the scientific objective. For example, it is up to volunteers to decide whether or not to participate if they meet the following criteria:\n\n* Age criteria (e.g.: specific, non-identifying range sought: 30-40 years)\n* BMI criteria (for example: BMI between 18.5 and 29 kg\u002Fm2)\n* Gender criteria (e.g.: women only)\n\nExclusion Criteria:\n\nSome of the following non-inclusion criteria may be defined according to the needs of the project:\n\n* Minor subject\n* Health criteria (e.g. presence or absence illness\u002Finfection\u002Fvaccination\u002Fallergy\u002Fanti-infective treatment in the last 3 months prior to the date of sampling)\n* Smoker status\n* Severe chronic illness (active cancer, HIV, severe renal failure, ongoing severe heart, liver or biliary disorders, arthritis)\n* Diagnosed acute or chronic gastrointestinal disease or complication (e.g. celiac disease, gastroesophageal reflux, gastric or duodenal ulcer, Crohn\\'s disease, hemorrhoids, irritable bowel syndrome),\n\nIn all cases, it will be requested that volunteers with the following criteria do not participate in the study:\n\n* Pregnant or breast-feeding women\n* Subjects under curatorship or guardianship\n* Subjects under legal protection.",{"count":59,"type":21},120,"OBSERVATIONAL","BIOASTER is a Technological Research Institute dedicated to microbiology and infectious diseases. BIAOSTER s areas of expertise are organized around four research programs: 1\u002F Antimicrobials; 2\u002F Vaccines; 3\u002F Microbiota; 4\u002F Diagnostics.\n\nHibiscus is a non-interventional, monocentric study aimed at building up a a collection of biological samples (stool, urine, saliva, buccal swab, nasal swab, superficial skin swab, hair) collected from BIOASTER employees. These samples to be used for scientific purposes including the technological development of Bioaster s collaborative and in-house research projects.",[63],"Biological Samples",[65,66,67],"Biological","samples","collection","NOT_YET_RECRUITING","2024-09-19",{"date":71,"type":41},"2024-09-20",{"date":73,"type":21},"2024-12-30",{"date":75,"type":21},"2027-12-31",{"name":47,"class":48},""]