[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Biocoz Global Pte. Ltd.\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":42},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":14,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":4,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":31,"lastUpdatePostDateStruct":32,"startDateStruct":35,"completionDateStruct":37,"leadSponsor":39,"locationsCount":5},"100611142","evaluation-of-spm-topical-cosmetic-application-on-skin-appearance-hydration-and-barrier-support-in-healthy-adults-100611142",false,"NCT07236736","Evaluation of SPM™ Topical Cosmetic Application on Skin Appearance, Hydration, and Barrier Support in Healthy Adults","SPMT","Inclusion Criteria:\n\n1. Generally healthy with no systemic or active dermatologic diseases.\n2. Willing and able to apply topical product daily for 6 weeks.\n3. Able to provide written informed consent.\n4. Willing to undergo skin biopsies and follow study procedures.\n\nExclusion Criteria:\n\n1. History of skin cancer or other malignancy within the past 10 years.\n2. Active or chronic dermatologic conditions (e.g., eczema, psoriasis, acne, rosacea).\n3. Known allergy or sensitivity to components of the investigational product.\n4. Current use of systemic corticosteroids or immunosuppressants.\n5. Pregnancy or breastfeeding.\n6. Any condition that, in the investigator's opinion, would interfere with study participation or pose additional risk.",true,"ALL","20 Years","75 Years",{"count":21,"type":22},10,"ESTIMATED","INTERVENTIONAL",[25],"NA","This is an exploratory, cosmetic-use study evaluating the effects of Super Protein Multifunction (SPM™), a topical peptide-based formulation, on skin appearance, hydration, and barrier-related characteristics in healthy adults. The study aims to collect preliminary biophysical and histologic data on cosmetic skin changes following six weeks of SPM™ use. Participants will apply the product to a designated skin area while a matched contralateral area serves as the untreated comparison site. Skin hydration, transepidermal water loss (TEWL), and tissue markers of skin structure and barrier integrity will be assessed before and after product use. The study includes noninvasive measurements and small punch biopsies at two timepoints.",[28,29],"Healthy Skin","Skin Hydration","NOT_YET_RECRUITING","2025-12-17",{"date":33,"type":34},"2025-12-19","ACTUAL",{"date":36,"type":22},"2026-01-30",{"date":38,"type":22},"2027-06-30",{"name":40,"class":41},"Biocoz Global Pte. Ltd.","INDUSTRY",""]