[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Biogem s.c.ar.l.\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":48},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":29,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":36,"lastUpdatePostDateStruct":37,"startDateStruct":40,"completionDateStruct":42,"leadSponsor":44,"locationsCount":47},"100605318","physical-exercise-to-prevent-mild-cognitive-impairment-in-patients-with-kidney-disfunctions-100605318",false,"NCT07160959","Physical Exercise to Prevent Mild-cognitive Impairment in Patients With Kidney Disfunctions","Physical Exercise to Prevent Mild-cognitive Impairment Progression in Advanced Chronic Kidney Disease (CKD) and Dialysis Patients","Exprecoimp-CKD","Inclusion Criteria:\n\n* CKD at KDOQI stage 4-5\n* concomitant MCI (MOCA - MMSE (17 \\\u003C MoCA \\\u003C 26) or (16 \\\u003C MMSE \\\u003C 24)\n\nExclusion Criteria:\n\n* Absolute contraindication to exercise training (e.g. unstable angina, major amputation, severe heart failure, etc.)\n* Known life expectancy \\\u003C 6-month\n* Uncorrected anemia (Hb \\\u003C9 g\u002Fdl)\n* Non-provision of informed consent","ALL","18 Years",{"count":20,"type":21},124,"ESTIMATED","INTERVENTIONAL",[24],"NA","This research project focuses on improving memory and thinking (cognitive function) in people with advanced chronic kidney disease (CKD), a condition that affects about 10% of adults and is often linked to cognitive problems. The study includes a clinical trial where patients will either receive standard care or follow a home-based exercise program involving walking and strength training, to see if regular physical activity can improve brain function. It also includes a large-scale analysis of data from the UK Biobank to explore blood and genetic markers, brain imaging, and lifestyle factors linked to cognitive health. The ultimate aim is to find effective, easy-to-implement strategies and early warning signs that could lead to better treatment and quality of life for people living with CKD.",[27,28],"Chronic Kidney Disease (Stages 4 and 5)","Mild Cognitive Impairment (MCI)",[30,31,32,33,34],"Chronic Kidney Disease (CKD)","stage G4-5 (CKD G4-5)","dialysis","physical exercise","cognitive function","NOT_YET_RECRUITING","2025-08-29",{"date":38,"type":39},"2025-09-08","ACTUAL",{"date":41,"type":21},"2026-01-01",{"date":43,"type":21},"2030-04-30",{"name":45,"class":46},"Biogem s.c.ar.l.","OTHER",6,""]