[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Bir Hospital\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":97},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,47,75],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":30,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":36,"lastUpdatePostDateStruct":37,"startDateStruct":40,"completionDateStruct":42,"leadSponsor":44,"locationsCount":4},"100643028","fragmentation-vs-dusting-with-fans-for-renal-stones-less-than-2cm-a-randomized-controlled-study-100643028",false,"NCT07639385","Fragmentation Vs Dusting With FANS for Renal Stones Less Than 2cm: A Randomized Controlled Study","Fragmentation Vs Dusting Using TFL With FANS for Renal Stones Less Than 2cm","Inclusion Criteria:\n\n* Age ≥18 years\n* Renal stone(s) confirmed on non-contrast CT KUB\n* Total stone less than 2cm\n* Stone amenable to flexible ureterorenoscopy (FURS)\n* FANS advanced beyond Pelvi-Ureteric Junction (PUJ)\n* Able and willing to provide written informed consent\n* Able to comply with follow-up schedule\n\nExclusion Criteria:\n\n* Active urinary tract infection (positive urine culture) at time of planned surgery\n* Anatomical anomalies precluding safe FURS (e.g., infundibular stenosis, severe calyceal diverticulum inaccessible to flexible scope)\n* Pregnancy or breastfeeding\n* Prior ipsilateral renal surgery within 3 months of enrollment\n* Concurrent ureteral stone(s) requiring simultaneous treatment\n* Renal anomalies: horseshoe kidney, ectopic kidney\n* Sheathless procedure\n* Unable to comply with follow-up or provide consent\n* Participation in another interventional trial within 30 days","ALL","18 Years",{"count":19,"type":20},86,"ESTIMATED","INTERVENTIONAL",[23],"NA","The use of FANS has changed the operative landscape of RIRS by allowing continuous active suction-assisted clearance of ablated stone material in real time. Use of fragmentation technique in FANS requires high-energy to reduce stone burden into small fragments, followed by active suction of residual fine material. Dusting with FANS, on the other hand, converts the entire stone volume into sub-millimetre particulate that is continuously suctioned away during lasing potentially offering a more streamlined workflow with potentially less energy usage, reduced mechanical stress on the ureteroscope working channel, and fewer scope withdrawals. The combination of TFL dusting with FANS-assisted real-time evacuation may produce stone-free outcomes equivalent or superior to fragmentation, while offering these additional operative efficiencies.\n\nWhether dusting using TFL with FANS is non-inferior or indeed superior to fragmentation using TFL with FANS in terms of stone-free rate at one month has not been evaluated in prospective randomised trial yet. This study aims to answer that specific question in patients with renal stone less than 2 cm.",[26,27,28,29],"Thulium Fiber Laser","Fans","Lithotripsy, Laser","Renal Stone",[31,32,33,34],"Dusting","Fragmentation","Thulium fiber laser","FANS","NOT_YET_RECRUITING","2026-06-26",{"date":38,"type":39},"2026-06-30","ACTUAL",{"date":41,"type":20},"2026-08-01",{"date":43,"type":20},"2027-08-07",{"name":45,"class":46},"Bir Hospital","OTHER_GOV",{"id":48,"slug":49,"hasResults":11,"nctId":50,"briefTitle":51,"officialTitle":52,"acronym":4,"eligibilityCriteria":53,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":54,"enrollmentInfo":55,"targetDuration":4,"studyType":21,"phases":57,"briefSummary":59,"conditions":60,"keywords":62,"overallStatus":66,"whyStopped":4,"lastUpdateSubmitDate":67,"lastUpdatePostDateStruct":68,"startDateStruct":70,"completionDateStruct":71,"leadSponsor":73,"locationsCount":74},"100577802","phase-3-study-of-tamsulosin-solifenacin-and-mirabegron-in-alleviating-ureteral-stent-related-symptoms-100577802","NCT06803030","Study of Tamsulosin, Solifenacin and Mirabegron in Alleviating Ureteral Stent-related Symptoms","A Comparative Study on the Efficacy of Tamsulosin, Solifenacin and Mirabegron in Alleviating Ureteral Stent-related Symptoms: a Randomized Controlled Trial","Inclusion Criteria:\n\n• Eligible participants were adult patients (aged 19-80 years) who underwent unilateral retrograde rigid ureteroscopy (URS) or retrograde intrarenal surgery (RIRS) with planned ureteric stent insertion for urinary tract stones\n\nExclusion Criteria:\n\n* Concomitant use of a-blockers, anticholinergics, corticosteroids, calcium channel blockers, and analgesics\n* Undergoing percutaneous nephrolithotomy, open ureteric surgery or laparoscopic ureteric surgery, including ureterolithotomy\n* Neurogenic bladder, Over Active Bladder (OAB) syndrome, and neurological and psychiatric diseases\n* Preoperative febrile Urinary Tract Infection (UTI)\n* Pregnancy or breastfeeding;\n* A single kidney\n* Moderate or severe cardiovascular or cerebrovascular disease\n* Hepatic dysfunction\n* History of pelvic surgery or irradiation\n* History of bladder or prostate surgery\n* Other acute medical conditions (including acute pancreatitis, acute gastroenteritis, musculoskeletal disorders) that might influence the Ureteral Stent Symptom Questionnaire(USSQ) pain score\n* Allergy to any medication","80 Years",{"count":56,"type":20},189,[58],"PHASE3","A comparative study on the efficacy of Tamsulosin, Solifenacin and Mirabegron in alleviating ureteral stent-related symptoms: a randomized controlled trial.",[61],"Ureteral Stent-Related Symptom",[63,64,65],"Mirabegron","Tamsulosin","Solifenacin","RECRUITING","2025-08-30",{"date":69,"type":39},"2025-09-08",{"date":67,"type":39},{"date":72,"type":20},"2026-12-31",{"name":45,"class":46},1,{"id":76,"slug":77,"hasResults":11,"nctId":78,"briefTitle":79,"officialTitle":80,"acronym":81,"eligibilityCriteria":82,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":54,"enrollmentInfo":83,"targetDuration":4,"studyType":21,"phases":85,"briefSummary":86,"conditions":87,"keywords":4,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":89,"lastUpdatePostDateStruct":90,"startDateStruct":92,"completionDateStruct":94,"leadSponsor":96,"locationsCount":74},"100579946","comparison-of-stent-related-symptoms-regular-double-j-stent-vs-comfi-j-stent-100579946","NCT06830902","Comparison of Stent-Related Symptoms: Regular Double J Stent vs. Comfi J Stent","Comparison of Stent Related Symptoms Between Regular Double J Stent Versus Comfi J Stent: A Single Blinded Randomized Controlled Trial","COMFIJ","Inclusion Criteria:\n\n* Eligible participants were adult patients (aged 18-80 years) who underwent unilateral retrograde ureteroscopy (URS) lithotripsy for stone disease\n* Retrograde intrarenal surgery (RIRS) lithotripsy with planned ureteric stent insertion for urinary tract stones\n\nExclusion Criteria:\n\n* Concomitant use of a-blockers, anticholinergics, corticosteroids, calcium channel blockers, and analgesics\n* Undergoing percutaneous nephrolithotomy, open ureteric surgery or laparoscopic ureteric surgery, including ureterolithotomy\n* Neurogenic bladder, Overactive bladder syndrome, and neurological and psychiatric diseases\n* Preoperative febrile Urinary Tract Infection (UTI)\n* Pregnancy or breastfeeding;\n* A single kidney\n* Moderate or severe cardiovascular or cerebrovascular disease\n* Hepatic dysfunction\n* History of pelvic surgery or irradiation\n* History of bladder or prostate surgery\n* Other acute medical conditions (including acute pancreatitis, acute gastroenteritis, musculoskeletal disorders) that might influence the USSQ pain score\n* Allergy to any medication",{"count":84,"type":20},100,[23],"A prospective, single-blinded, randomized controlled trial conducted at a single center to compare stent related symptoms between two different stents using Ureteral Stent Symptom Questionnaire (USSQ) scores , Visual Analog Scale (VAS) pain scores.",[88],"Stent Related Symptoms","2025-02-18",{"date":91,"type":39},"2025-02-19",{"date":93,"type":20},"2025-02-15",{"date":95,"type":20},"2025-09-15",{"name":45,"class":46},""]