[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Bournemouth University\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":173},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,5,0,[8,51,78,110,145],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":23,"conditions":24,"keywords":30,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":40,"lastUpdatePostDateStruct":41,"startDateStruct":44,"completionDateStruct":46,"leadSponsor":48,"locationsCount":4},"100637543","high-intensity-use-of-urgent-and-emergency-care-a-mixed-methods-study-100637543",false,"NCT07630012","High Intensity Use of Urgent and Emergency Care: A Mixed-Methods Study","High Intensity Use of Urgent and Emergency Care: a Mixed-methods Study Exploring Needs, Experiences and Priorities to Co-produce a Preventative Intervention Model","Inclusion Criteria:\n\nAdults aged 18 or over who have been identified as experiencing high intensity use of urgent and emergency care services at University Hospitals Dorset, defined as five or more unplanned contacts within a 12-month period Adults aged 18 or over who provide unpaid care or support to someone who experiences high intensity use of urgent and emergency care services Health and social care professionals aged 18 or over involved in urgent and emergency care pathways at University Hospitals Dorset, Dorset HealthCare, Dorset Council or voluntary sector partner organisations Able to provide informed consent Willing to take part in an audio-recorded interview-\n\nExclusion Criteria:\n\nUnder 18 years of age Unable to provide informed consent Currently experiencing an acute mental health crisis requiring immediate clinical intervention Known history of violence or aggression towards health and social care professionals Currently receiving inpatient treatment at the time of recruitment No direct involvement in urgent and emergency care pathways at the participating organisations (professionals only)",true,"ALL","18 Years",{"count":20,"type":21},80,"ESTIMATED","OBSERVATIONAL","This study aims to understand the health and social care needs and experiences of adults who frequently use urgent and emergency care services in Dorset. Using a mixed-methods design, the study combines analysis of non-patient-identifiable business intelligence data with qualitative interviews and co-production activities. The business intelligence data contextualises patterns of high intensity service use and informs participant identification. Qualitative interviews will explore the personal, social and system-level factors that contribute to frequent attendance. Co-production activities with an advisory group, supported by The Lantern Trust in Weymouth, will use these findings to develop a preventative intervention model grounded in lived experience. The study will recruit up to 50 patients, up to 10 carers and up to 20 health and social care professionals. The findings will contribute to the development of more effective, person-centred approaches to supporting people who frequently use urgent and emergency care services and will inform national and local policy in this area.",[25,26,27,28,29],"High Intensity Use of Urgent and Emergency Care","Emergency Medicine","Health Inequalities","Mental Health","Alcohol Use Disorder (AUD)",[31,32,33,34,35,36,37,38],"High intensity use","Frequent attenders","Urgent and emergency care","Mixed methods","Co-production","Qualitative research","Health and social care needs","Preventative intervention","NOT_YET_RECRUITING","2026-06-01",{"date":42,"type":43},"2026-06-05","ACTUAL",{"date":45,"type":21},"2026-09-01",{"date":47,"type":21},"2029-04-01",{"name":49,"class":50},"Bournemouth University","OTHER",{"id":52,"slug":53,"hasResults":11,"nctId":54,"briefTitle":55,"officialTitle":56,"acronym":57,"eligibilityCriteria":58,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":59,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":61,"conditions":62,"keywords":68,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":70,"lastUpdatePostDateStruct":71,"startDateStruct":73,"completionDateStruct":74,"leadSponsor":76,"locationsCount":77},"100639596","tb-stigma-in-the-uk-patients-experiences-and-everyday-responses-100639596","NCT07609264","TB Stigma in the UK: Patients Experiences and Everyday Responses","Making Sense of Tuberculosis (TB) Related Stigma in a Low-incidence Area of the UK: Patients Experiences and Everyday Responses","TB stigma","This study seeks participants who have been diagnosed with pulmonary TB, extrapulmonary TB, latent TB infection (LTBI), and drug sensitive or drug resistant TB within the last 10 years. Participants may have different cultural and socioeconomic backgrounds and will be resident within a pre-defined TB low-incidence coastal\u002Frural area of the UK.\n\nInclusion criteria\n\n* Aged 18 or over at start of study\n* Resident in rural or coastal areas within South or Southwest England\n* Diagnosed with either active or latent TB within the last 10 years\n\nExclusion criteria\n\n* Lacks mental capacity or is unwilling to consent to participate in the study\n* Under 18 years of age\n* Lives in an area of TB high-incidence (above 10 cases\u002F100,000 population) or outside of rural and coastal areas of South\u002FSouthwest England",{"count":60,"type":21},20,"Public understanding of tuberculosis (TB) is shaped by sociocultural norms, educational background, and personal experiences. Misconceptions about TB transmission, disease severity, and treatment side effects are widespread, contributing to stigma and fear of social rejection. Such stigma can lead individuals to conceal their diagnosis, limiting access to support, engagement with healthcare, and overall health literacy.\n\nTB-related stigma is recognised as a significant barrier to ending the global TB epidemic, affecting quality of life and access to care. Yet in high-income, low-incidence (HILI) countries like the UK, its prevalence, influence, and lived impact remain largely unexplored. Where stigma appears in research, it is often treated as an emerging theme, leaving a critical gap in understanding how individuals with TB, or those caring or supporting them, experience and respond to it.\n\nThis study adopts a Constructivist Grounded Theory (CGT) approach to examine TB-related stigma in depth. CGT allows the research to explore how people living with TB make sense of, interpret, negotiate, and resist stigma, capturing the dynamic and contextual ways it shapes their lives, identities, and interactions with healthcare systems. By investigating these meaning-making processes, the study aims to illuminate how stigma operates in the UK, providing insights to inform future stigma-reduction interventions, communication strategies, and supportive healthcare practices, ultimately benefiting patients, communities, and the NHS.",[63,64,65,66,67],"TB","Tuberculosis","Stigma","TB Stigma","Low Incidence",[63,64,65,69,57],"Low incidence","2026-05-21",{"date":72,"type":43},"2026-05-27",{"date":45,"type":21},{"date":75,"type":21},"2028-03-01",{"name":49,"class":50},1,{"id":79,"slug":80,"hasResults":11,"nctId":81,"briefTitle":82,"officialTitle":83,"acronym":84,"eligibilityCriteria":85,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":86,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":88,"conditions":89,"keywords":92,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":101,"lastUpdatePostDateStruct":102,"startDateStruct":104,"completionDateStruct":106,"leadSponsor":108,"locationsCount":109},"100629174","dressing-related-experiences-and-surgical-site-self-care-in-hip-and-knee-replacement-an-observational-cohort-study-100629174","NCT07471243","Dressing-related Experiences and Surgical Site Self-care in Hip and Knee Replacement: an Observational Cohort Study","Dressing-Related Experiences and Surgical Site Self-Care in Hip and Knee Replacement: an Observational Cohort Study (DRESS-X)","DRESS-X","Inclusion Criteria:\n\n* Adults (18+) undergoing primary total hip or knee replacement\n* Enrolled in an ERAS protocol\n* Willing and able to provide informed consent\n\nExclusion Criteria:\n\n* Requiring revision replacement\n* Unable to provide informed consent (cognitive disorder such as dementia, psychiatric illness)\n* Unable to understand written English",{"count":87,"type":21},100,"The goal of this prospective observational cohort study is to investigate dressing-related experiences and surgical site self-care in patients who are undergoing a total hip or knee replacement. The main objectives of the study are:\n\n* To evaluate patient adherence to the ISWCAP self-care checklist after total hip or knee replacement within an ERAS pathway.\n* To explore patient-reported outcomes related to the performance and comfort of advanced dressings.\n* To assess the perceived adequacy and usefulness of post-discharge wound care education.\n* To identify the incidence and types of wound-related complications in the 12 weeks following surgery.\n\nParticipants will give informed consent before surgery and will start the study once the dressing has been applied following surgery. There will be follow up study visits at discharge, 7 days, 12 days, 6 weeks and 12 weeks post-surgery. Data relating to vital signs, medical history, surgery and medication will be taken from routine data.",[90,91],"Total Hip Replacement","Total Knee Replacement",[93,94,95,96,97,98,99,100],"Hip arthroplasty","Hip replacement","Knee arthroplasty","Knee replacement","Musculoskeletal","Enhanced recovery after surgery","ERAS","Surgical wound","2026-03-10",{"date":103,"type":43},"2026-03-13",{"date":105,"type":21},"2026-04-01",{"date":107,"type":21},"2027-08-31",{"name":49,"class":50},2,{"id":111,"slug":112,"hasResults":11,"nctId":113,"briefTitle":114,"officialTitle":115,"acronym":4,"eligibilityCriteria":116,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":117,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":119,"conditions":120,"keywords":129,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":137,"lastUpdatePostDateStruct":138,"startDateStruct":140,"completionDateStruct":142,"leadSponsor":144,"locationsCount":4},"100601744","addressing-pregnant-womens-first-trimester-worries-and-information-needs-with-mhealth-solutions-100601744","NCT07114471","Addressing Pregnant Women's First Trimester Worries and Information Needs With mHealth Solutions","Exploring the Anxieties and Health Information Needs of Women in the First Trimester to Inform mHealth Solutions for Antenatal Care","Pregnant women\n\nInclusion criteria\n\n* To ensure that participants have the first trimester of pregnancy fresh in their minds the sample will include women that are currently pregnant or have had a child within the last 2 years\n* Living in the UK\n* Over the age of 18\n* Able to give informed consent Exclusion criteria\n* Evidence of\u002Fdiagnosis of cognitive impairment\n\nHealthcare professionals\n\nInclusion criteria\n\n\\- Belonging to one of the following professional groups i.e. healthcare professionals involved in the care of pregnant women\n\n* Doctor in obstetrics and gynaecology\n* Midwives\n* Nurses (within the field of obstetrics and gynaecology),\n* Sonographers that scan pregnant women\n* General practitioners\n* Psychologists (that work with pregnant women)\n* Physiotherapists (that work with pregnant women)\n* Living in the UK\n* Over the age of 18\n* Able to give informed consent Exclusion criteria\n* Evidence of\u002Fdiagnosis of cognitive impairment\n\nDigital Health Experts\n\nInclusion criteria\n\n* Professionals with at least 3 year's experience in digital health, health informatics or mobile health application development\n* Based in the United Kingdom Exclusion criteria\n* Evidence of\u002Fdiagnosis of cognitive impairment",{"count":118,"type":21},1450,"The first 12 weeks of pregnancy, known as the first trimester, can be one of the most worrying times for women. (Where this lay summary refers to women, it should be taken to include people who do not identify as women but who have the capacity to become pregnant). Many experience nausea, bleeding, or anxiety about whether the pregnancy is progressing normally. Despite this, most women do not see a midwife or doctor until around 10 weeks into the pregnancy. This leaves a gap where they may have important questions but little professional support. As a result, many turn to mobile phone applications or the internet to find answers - but the quality of information online is mixed, and it can be confusing or even unsafe.\n\nThis research aims to understand what support women really need in early pregnancy, what concerns they have, and whether a mobile health application (mHealth app) could help fill this gap in current pregnancy care in a safe and personalised way. The study will also ask healthcare professionals and digital health experts what such an application should include, and how it can be made accessible, and easy to understand for all women - including those with different levels of health knowledge and digital skills.\n\nTo carry out the research, we will use a combination of online surveys and interviews. Women who are currently pregnant or have had a baby in the last two years will be invited to take part, along with healthcare professionals such as midwives and doctors, and experts in digital health. The survey will ask about their experiences in early pregnancy, how they have used digital tools or apps, and whether they felt their questions were answered before their first NHS appointment. The interview stage will allow participants to talk in more depth about what support they wanted and what would have helped them most. All participants will receive information about support services because we realise that discussing unmet information needs or worries in early pregnancy may be upsetting for some women.\n\nThe views collected will inform the design of a new mobile application to support women during early pregnancy. The application will use artificial intelligence (AI) to personalise information based on each woman's needs and background, and to explain things clearly and simply. The content and design of the application will be reviewed by doctors and digital health specialists to make sure it is safe, accurate, and easy to use.\n\nPublic and patient involvement is central to this project. A diverse group of women and representatives from grassroots organisations will be invited to shape the questions we ask, review the design of the application, and help us make it inclusive for people from different backgrounds.\n\nThis research will help us create a practical, trustworthy, and inclusive tool to support women during one of the most vulnerable times in pregnancy when women don't usually see a doctor. If successful, it could be used widely across the NHS to help reduce anxiety, improve understanding, and ensure women get the right support earlier in their pregnancy with the long-term aim of improving outcomes for women, babies, and families across the UK.",[121,122,123,124,125,126,127,128],"Pregnancy Trimester, First","Anxiety","Worries","Health Knowledge, Attitudes, Practice","mHealth Application","Mobile Application","Antenatal Care","Patient Education as Topic",[130,131,132,133,134,135,136],"Observational Study","Surveys and Questionnaires","Interview","Digital Health","Health Literacy","Pregnant People","User Centered Design","2025-08-11",{"date":139,"type":43},"2025-08-14",{"date":141,"type":21},"2025-09",{"date":143,"type":21},"2027-10",{"name":49,"class":50},{"id":146,"slug":147,"hasResults":11,"nctId":148,"briefTitle":149,"officialTitle":150,"acronym":151,"eligibilityCriteria":152,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":153,"targetDuration":4,"studyType":154,"phases":155,"briefSummary":157,"conditions":158,"keywords":162,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":166,"lastUpdatePostDateStruct":167,"startDateStruct":169,"completionDateStruct":170,"leadSponsor":172,"locationsCount":77},"100594832","preoperative-serial-casting-education-and-therapy-for-dupuytrens-contracture-100594832","NCT07024576","Preoperative Serial Casting, Education, and Therapy for Dupuytren's Contracture","Preoperative Serial Casting, Stretching, and Massage Therapy Package for Dupuytren's Patients With Severe Proximal Interphalangeal Joint Contracture: A Feasibility Study Protocol for a Randomised Trial","PRESCET","Inclusion Criteria:\n\n* Male or female participants aged 18 years or older.\n* One or more fingers with a Dupuytren's flexion contracture greater than 30° at the PIP joint.\n* Awaiting fasciectomy surgery for Dupuytren's contracture.\n* Willing and able to provide informed consent for participation in the study.\n\nExclusion Criteria:\n\n* Individuals awaiting needle fasciotomy, dermofasciectomy, or segmental fasciectomy.\n* A history of previous treatment for Dupuytren's contracture (e.g., surgery, collagenase injection, or needle fasciectomy) to the study reference digit.\n* A history of any other pre-existing hand disorder causing significant movement restriction, pain, or affecting hand function (e.g., post-traumatic stiffness, arthritis, infection).\n* Non-English speaking participants due to the need for completing multiple questionnaires that have not been validated in multiple languages.\n* Inability to attend follow-up appointments within the required timeframes.",{"count":60,"type":21},"INTERVENTIONAL",[156],"NA","We are running a small study to test whether a special type of therapy - including casting, stretching, and massage - might help improve recovery after Dupuytren's Fasciectomy.\n\nThe study is taking place at Dorset County Hospital and will involve people who are already scheduled for surgery and have a permanent bend of 30 degrees or more in the middle joint of one or more fingers.\n\nThe therapy will be given before surgery to see if it helps people get a better result afterwards.\n\nWe want to find out:\n\n* Who would be suitable to take part in a future, larger study\n* Which results are most important to measure (like finger movement or grip strength)\n* How many people complete the full therapy and follow-up We'll also speak to patients and healthcare professionals to understand how acceptable and practical this therapy is.\n\nThe goal is to see whether it's possible and worthwhile to run a larger study in the future, to find out if pre-surgery therapy can become a helpful part of treatment for people undergoing Dupuytren's Fasciectomy.",[159,160,161],"Dupuytren&Amp;#39;s Contracture","Dupuytren&Amp;#39;s Fasciectomy","Dupuytren&Amp;#39;s Disease",[163,164,165],"Dupuytren's","Fasciectomy","Preoperative therapy","2025-06-09",{"date":168,"type":43},"2025-06-17",{"date":141,"type":21},{"date":171,"type":21},"2026-09",{"name":49,"class":50},""]