[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Bradley Hospital\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":204},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,7,0,[8,46,70,115,135,149,170],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":28,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":34,"lastUpdatePostDateStruct":35,"startDateStruct":38,"completionDateStruct":40,"leadSponsor":42,"locationsCount":45},"100053435","culturally-centered-cbt-protocol-for-suicidal-behaviors-among-youth-in-mexico-city-100053435",false,"NCT06885047","Culturally Centered CBT Protocol for Suicidal Behaviors Among Youth in Mexico City","Implementation and Pilot Testing of a Culturally Centered CBT Protocol for Suicidal Behaviors Among Youth in Mexico City","Youth Inclusion Criteria:\n\n* ages 12 to 17,\n* severe SI, defined as a score of 22 or above on the SIQ-JR or having made a SA or having a suicidal crisis (e.g., threats of attempting suicide) within the last 3 months\n* not be engaged in mental health services outside HPIJNN.\n\nExclusion Criteria:\n\n* having a diagnosis of a psychotic disorder\n* having a diagnosis of substance use disorder, rated severe on the DSM-593 (i.e., endorsement of 6 or more symptoms),\n* not having sufficient cognitive ability to enter a psychotherapy service (whether reported by the parents or by data in the clinical record)","ALL","12 Years","17 Years",{"count":20,"type":21},60,"ESTIMATED","INTERVENTIONAL",[24],"NA","This NIMH R34 award application proposes to conduct an adaptation, implementation, and pilot testing of the culturally centered CBT protocol, the Socio-Cognitive Behavioral Therapy for Suicidal Behaviors (SCBTSB), among suicidal youth in Mexico City, Mexico.\n\nThe research plan will (a) culturally adapt and contextualize the SCBT-SB for its implementation in the Mexican public health system, (b) pilot test the protocol through an RCT (SCBT-SB vs TAU; 60 patients and caregivers) and (c) evaluate the implementation process of the SCBT-SB and assess qualitatively possible factors that may promote or hinder its future uptake.",[27],"Suicidal Ideation\u002FBehavior",[29,30,31,32],"Randomized Controlled Trial","Mexico youth","cultural adaptation","cognitive behavioral therapy","NOT_YET_RECRUITING","2026-07-10",{"date":36,"type":37},"2026-07-13","ACTUAL",{"date":39,"type":21},"2026-09",{"date":41,"type":21},"2027-06",{"name":43,"class":44},"Bradley Hospital","OTHER",1,{"id":47,"slug":48,"hasResults":11,"nctId":49,"briefTitle":50,"officialTitle":51,"acronym":4,"eligibilityCriteria":52,"healthyVolunteers":53,"sex":16,"minAge":54,"maxAge":4,"enrollmentInfo":55,"targetDuration":4,"studyType":22,"phases":57,"briefSummary":58,"conditions":59,"keywords":4,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":62,"lastUpdatePostDateStruct":63,"startDateStruct":65,"completionDateStruct":67,"leadSponsor":69,"locationsCount":4},"100558313","a-sleep-intervention-for-preschoolers-in-foster-care-100558313","NCT06549491","A Sleep Intervention for Preschoolers in Foster Care","Development and Implementation of a Digital Sleep Intervention for Preschoolers in Foster Care","Inclusion Criteria:\n\n* Participants are only recruited for Aims 2 (Nurturing Sleep pretest) and 3 (RCT of Nurturing Sleep) of the study and must be a US foster parent of a preschool aged child (36 to 71 months) and have a smartphone. Foster parents will be adults 21 years of age or older, per federal requirements for foster parent licensing.\n\nExclusion Criteria:\n\n* Participants will be excluded from the study if they are not English or Spanish speaking, or if the child they are to report on has a serious medical condition or developmental disability that the sleep intervention would not be appropriate for because their medical condition requires more specialized strategies (e.g., cerebral palsy, seizures, autism spectrum disorders). If there is more than one preschool aged child under the foster parent's care, they will implement the intervention and answer study questionnaires based on the child for whom they are most concerned about their sleep.",true,"21 Years",{"count":56,"type":21},72,[24],"Healthy sleep is critical for optimal health and development, but there are no public health interventions to support sleep for children in foster care. This proposal will develop and implement a digital public-health-level intervention to support foster caregivers in promoting healthy sleep in the young children in their care. The digital intervention approach has the potential to maximize scalability and reach to support foster children and their caregivers on a national level.",[60,61],"Sleep","Foster Care","2026-06-23",{"date":64,"type":37},"2026-06-29",{"date":66,"type":21},"2027-12-01",{"date":68,"type":21},"2030-06-30",{"name":43,"class":44},{"id":71,"slug":72,"hasResults":11,"nctId":73,"briefTitle":74,"officialTitle":75,"acronym":76,"eligibilityCriteria":77,"healthyVolunteers":11,"sex":16,"minAge":78,"maxAge":79,"enrollmentInfo":80,"targetDuration":4,"studyType":22,"phases":82,"briefSummary":83,"conditions":84,"keywords":100,"overallStatus":106,"whyStopped":4,"lastUpdateSubmitDate":107,"lastUpdatePostDateStruct":108,"startDateStruct":110,"completionDateStruct":112,"leadSponsor":114,"locationsCount":45},"100587910","implementing-team-based-treatment-for-pediatric-anxiety-in-community-mental-health-settings-100587910","NCT06934525","Implementing Team-Based Treatment for Pediatric Anxiety in Community Mental Health Settings","Testing Delivery of Modalities in Community Health Settings: Developing Pathways to Health Equity","IMPACT-RI","Inclusion Criteria:\n\n* Age 5-18 inclusive\n* Primary or co-primary DSM-V diagnosis of anxiety or OCD\n* Symptom duration of at least 3 months\n* Outpatient care needed\n* Presence of a stable parent, or guardian, who can participate in treatment\n\nExclusion Criteria:\n\n* Other primary or co-primary psychiatric disorder which requires initiation of other active current treatment\n* Acute suicidality\n* Concurrent psychotherapy\n* Chronic medical illness that would preclude their active participation in treatment\n* Treatment with psychotropic medication that is not stable","5 Years","18 Years",{"count":81,"type":21},501,[24],"The purpose of this study is to test how the delivery of Cognitive Behavioral Therapy (CBT) for pediatric anxiety and OCD via different methods might increase its availability and effectiveness. CBT involves teaching the patient skills to enable them to gradually come into contact with feared situations. This process of gradually approaching feared situations is called exposure. Although CBT with exposure has the best evidence for treating anxiety disorders, not all children have equal access or respond the same way to CBT. As part of this study, patients will receive weekly CBT treatment sessions involving a combination of weekly visits with an exposure coach and one visit a month with a licensed provider (e.g., psychologist, social worker). This treatment will be delivered using one of three methods: 1) in-person (face-to-face sessions, occurring in the office and the home\u002Fcommunity), or 2) telehealth (entirely remote sessions via web-based video conference), or 3) flexible (individualized mix of in-person and\u002For telehealth sessions). Eligible participants will be randomly assigned to one of these three methods. Results of this study will help determine which treatment method works best for whom.\n\nTreatment as described above will occur as part of care at partnering community care sites in Rhode Island. Providers from the following partnering community care sites will make up patient treatment teams: Blackstone Valley Community Health Care, Family Services of Rhode Island, Gateway Healthcare, Newport Mental Health, and Thrive Behavioral Health.\n\nThe research study is being conducted by the Pediatric Anxiety Research Center at Brown University Health. The research team will conduct the study assessments that patients will be asked to participate in as study participants. Patients will be asked to complete assessments prior to starting treatment, at two time points during treatment, at the end of treatment, and at two timepoints 3 and 6 months following the end of treatment. Participants will be compensated for their time completing research assessments.",[85,86,87,88,89,90,91,92,93,94,95,96,97,98,99],"Obsessive Compulsive Disorder (OCD)","Pediatric Anxiety Disorders","Anxiety Disorder","Anxiety","OCD","Phobia","Agoraphobia","Generalized Anxiety","Generalized Anxiety Disorder","Selective Mutism","Separation Anxiety","Social Anxiety","Social Anxiety Disorder","Panic Disorder","Pediatric Disorders",[101,32,102,103,104,105],"exposure therapy","anxiety treatment","exposure and response prevention therapy","ERP","pediatric anxiety treatment","RECRUITING","2026-05-13",{"date":109,"type":37},"2026-05-14",{"date":111,"type":37},"2025-11-01",{"date":113,"type":21},"2029-08-01",{"name":43,"class":44},{"id":116,"slug":117,"hasResults":11,"nctId":118,"briefTitle":119,"officialTitle":119,"acronym":4,"eligibilityCriteria":120,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":79,"enrollmentInfo":121,"targetDuration":4,"studyType":22,"phases":123,"briefSummary":124,"conditions":125,"keywords":4,"overallStatus":106,"whyStopped":4,"lastUpdateSubmitDate":127,"lastUpdatePostDateStruct":128,"startDateStruct":130,"completionDateStruct":132,"leadSponsor":134,"locationsCount":45},"100490142","nimh-k23-modulation-of-frontoparietal-dynamics-in-adolescent-working-memory-deficits-100490142","NCT05662280","NIMH K23: Modulation of Frontoparietal Dynamics in Adolescent Working Memory Deficits","Researchers will enroll a sample of adolescents (age 12-18 years) with working memory deficits and ADHD. Participation in this study will not require any adjustments to their clinical care. There are no costs to this study (participants compensated) and there are no expected long-term benefits to the participants. Participants will be compensated for each session. Participants can withdraw from the study at any time.\n\nInclusion Criteria\n\n1. Ability to provide assent and have parent provide parental permission\n2. English fluency of the participant and the legal guardian\u002Fparent\n3. 12-18 years\n4. Parent rating on BRIEF-2 Working Memory: Greater than 1.0 SD above normative mean.\n5. IQ \\> 80\n6. Clinical diagnosis of attention deficit hyperactivity disorder (ADHD): predominantly inattentive type, predominantly hyperactive\u002Fimpulsive type, combined type, or unspecified type. Diagnostic criteria will be confirmed with NICHQ Vanderbilt Assessment Scales-Parent.\n\nExclusion Criteria: Participants will be screened to exclude individuals with neurological or medical conditions that might confound the results, as well as to exclude participants in whom MRI or TMS might result in increased risk of side effects or complications. Common contraindications include metallic hardware in the body, cardiac pacemaker, patients with an implanted medication pumps or an intracardiac line, or prescription of medications known to lower seizure threshold. These account for the majority of the exclusion criteria listed below:\n\n1. Intracranial pathology from a known genetic disorder (e.g., NF1, tuberous sclerosis) or from acquired neurologic disease (e.g. stroke, tumor), cerebral palsy, history of severe head injury, or significant dysmorphology\n2. History of fainting spells of unknown or undetermined etiology that might constitute seizures\n3. History of seizures, diagnosis of epilepsy, or immediate (1st degree relative) family history epilepsy\n4. Any progressive (e.g., neurodegenerative) neurological disorder\n5. Chronic (particularly) uncontrolled medical conditions that may cause a medical emergency in case of a provoked seizure (cardiac malformation, cardiac dysrhythmia, asthma, etc.)\n6. Contraindicated metal implants in the head, brain or spinal cord (excluding dental implants, braces or fillings)\n7. Non-removable makeup or piercings\n8. Pacemaker\n9. Implanted medication pump\n10. Vagal nerve stimulator\n11. Deep brain stimulator\n12. TENS unit (unless removed completely for the study)\n13. Ventriculo-peritoneal shunt\n14. Signs of increased intracranial pressure\n15. Intracranial lesion (including incidental finding on MRI)\n16. History of head injury resulting in prolonged loss of consciousness\n17. Substance abuse or dependence within past six months (i.e., DSM-5 substance use disorder criteria)\n18. Chronic treatment with prescription medications that decrease cortical seizure threshold, not including psychostimulant medication if deemed to be medically safe as part of the medical review process.\n19. Active psychosis or mania\n20. Current suicidal intent\n21. Current pregnancy\n22. Significant visual, hearing or speech impairment\n23. Current wards of the state",{"count":122,"type":21},40,[24],"Working memory (WM) deficits are a transdiagnostic feature of adolescent psychopathology that substantially contribute to poor clinical and functional outcomes. This proposal will utilize a multimodal neuroscientific approach to investigate whether non-invasive brain stimulation can modulate the neural mechanisms underlying adolescent WM deficits. Directly in line with NIMH priorities, the researchers will identify the contributing roles of prefrontal and parietal regions in WM processes, as well as identify optimal targets and parameters for novel brain-based treatments in adolescent psychopathology. This study is funded by the NIMH-K23",[126],"Working Memory","2026-04-27",{"date":129,"type":37},"2026-05-01",{"date":131,"type":37},"2022-12-01",{"date":133,"type":21},"2026-12-01",{"name":43,"class":44},{"id":136,"slug":4,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":137,"targetDuration":4,"studyType":22,"phases":138,"briefSummary":25,"conditions":139,"keywords":140,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":141,"lastUpdatePostDateStruct":142,"startDateStruct":144,"completionDateStruct":146,"leadSponsor":148,"locationsCount":45},"100584108",{"count":20,"type":21},[24],[27],[29,30,31,32],"2026-04-01",{"date":143,"type":37},"2026-04-07",{"date":145,"type":21},"2026-06-01",{"date":147,"type":21},"2028-06-30",{"name":43,"class":44},{"id":150,"slug":151,"hasResults":11,"nctId":152,"briefTitle":153,"officialTitle":153,"acronym":154,"eligibilityCriteria":155,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":79,"enrollmentInfo":156,"targetDuration":4,"studyType":22,"phases":158,"briefSummary":159,"conditions":160,"keywords":4,"overallStatus":106,"whyStopped":4,"lastUpdateSubmitDate":162,"lastUpdatePostDateStruct":163,"startDateStruct":165,"completionDateStruct":167,"leadSponsor":169,"locationsCount":45},"100609840","accelerated-itbs-targeting-of-working-memory-versus-inhibitory-control-in-adolescent-adhd-100609840","NCT07219810","Accelerated iTBS Targeting of Working Memory Versus Inhibitory Control in Adolescent ADHD","WINK","Inclusion Criteria\n\n1. Age 12-18 years\n2. English fluency of participant and parent and able to provide informed consent\u002Fassent\n3. Clinical diagnosis of ADHD and confirmation of diagnostic criteria on the Diagnostic Interview for Anxiety, Mood, and OCD and Related Neuropsychiatric Disorders, Child and Adolescent Version (DIAMOND-KID)\n4. Parent rating on The Behavior Rating Inventory of Executive Function-Second Edition (BRIEF-2), Parent Form: Working Memory scale T-Score \\> 60 AND Inhibition scale T-Score \\> 60\n5. IQ \\> 70\n\nExclusion Criteria\n\nParticipants will be screened to exclude individuals with neurological or medical conditions that might confound the results, as well as to exclude participants in whom MRI or TMS might result in increased risk of side effects or complications. Common contraindications include metallic hardware in the body, cardiac pacemaker, patients with an implanted medication pumps or an intracardiac line, or prescription of medications known to lower seizure threshold. These account for most of the exclusion criteria listed below:\n\n1. Intracranial pathology from a known genetic disorder (e.g., NF1, tuberous sclerosis) or from acquired neurologic disease (e.g. stroke, tumor), cerebral palsy, history of severe head injury, or significant dysmorphology\n2. History of fainting spells of unknown or undetermined etiology that might constitute seizures\n3. History of seizures, diagnosis of epilepsy, or immediate (1st degree relative) family history epilepsy\n4. Any progressive (e.g., neurodegenerative) neurological disorder\n5. Chronic (particularly) uncontrolled medical conditions that may cause a medical emergency in case of a provoked seizure (cardiac malformation, cardiac dysrhythmia, asthma, etc.)\n6. Contraindicated metal implants in the head, brain or spinal cord (excluding dental implants or fillings)\n7. Non-removable makeup or piercings\n8. Pacemaker, implanted medication pump, or ventriculo-peritoneal shunt\n9. Vagal nerve stimulator, deep brain stimulator, or transcutaneous electrical nerve stimulation unit\n10. Signs of increased intracranial pressure\n11. Intracranial lesion\n12. History of head injury resulting in prolonged loss of consciousness\n13. Substance abuse or dependence within past six months (i.e., DSM-5 substance use disorder criteria)\n14. Chronic treatment with prescription medications that decrease cortical seizure threshold, not including psychostimulant medication if deemed to be medically safe as part of the medical review process.\n15. Active psychosis or mania\n16. Acute suicidal intent\n17. Current pregnancy\n18. Significant visual, hearing or speech impairment\n19. Dental braces\n20. Current wards of the state",{"count":157,"type":21},50,[24],"The objective of this project is to examine the differential therapeutic effect of intermittent theta burst stimulation (iTBS; a type of repetitive transcranial magnetic stimulation) to the left DLPFC versus right PreSMA in modulating working memory (WM) versus inhibitory control (IC) deficits. Fifty adolescents (12-18 years old) with parent-reported WM and IC deficits and diagnosed ADHD will be randomized to DLPFC or PreSMA targeted 3x-daily iTBS for a total of ten days (30 total sessions).",[161],"ADHD","2025-10-20",{"date":164,"type":37},"2025-10-22",{"date":166,"type":37},"2025-09-01",{"date":168,"type":21},"2029-09-01",{"name":43,"class":44},{"id":171,"slug":172,"hasResults":11,"nctId":173,"briefTitle":174,"officialTitle":175,"acronym":4,"eligibilityCriteria":176,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":79,"enrollmentInfo":177,"targetDuration":4,"studyType":22,"phases":179,"briefSummary":180,"conditions":181,"keywords":185,"overallStatus":106,"whyStopped":4,"lastUpdateSubmitDate":196,"lastUpdatePostDateStruct":197,"startDateStruct":199,"completionDateStruct":201,"leadSponsor":203,"locationsCount":45},"100583935","a-new-clinical-model-for-the-engagement-of-latinx-youth-with-suicidal-behavior-100583935","NCT06882798","A New Clinical Model for the Engagement of Latinx Youth With Suicidal Behavior","A New Clinical Model for the Engagement of Latinx Youth With Suicidal Behavior and Their Families in a Culturally Centered CBT Treatment","Inclusion Criteria:\n\n* Latinx, defined as have been born in a Latin country or having at least one biological parent, grandparent or an ancestor that was born in a Latin country\n* Severe Suicidal Ideation (SI), defined as one of the following:\n* SIQ-JR \\> 22 or endorsing any critical items (2, 3, 4, 7, 8, 9) with at least \"about 1x\u002Fmonth\"\n* CDI-II \\> 15 and endorsing \"I think about killing myself but would not do it\" OR \"I think about killing myself.\"\n* PHQ-9 \\> 10 \\& endorsing the item \"Thoughts that you would be better off dead, or of hurting yourself in some way\" with a frequency of \"several days\" or greater or endorsing the item \"Has there been a time in the past month when you have had serious thoughts about ending your life?\n* Suicidal crisis within the past 12 months\n* Caregivers and adolescents fluent in Spanish or English language and legal guardian willing to participate\n\nExclusion Criteria:\n\n* Participants will be referred to a different treatment program if their main clinical complaint is any of the following:\n* Behavioral (e.g., conduct disorder, or substance use disorder)\n* An eating disorder\n* Obsessive-compulsive disorder\n* A developmental issue (e.g., speech, occupational, families looking for assessments, treatment for autism) or a significant cognitive delay that may require specialized treatment adjustments.",{"count":178,"type":21},150,[24],"This study will test a model of providing treatment to Latinx\u002FHispanic youth, who experience suicidal thoughts and behavior, and their caregivers. An affirmative and culturally relevant treatment will be provided to all youth and half of the families will be assigned to the additional support of a community health worker (CHW). Youth symptoms and family engagement to treatment will be followed for nine months. The potential benefit of adding the CHW intervention will be assessed.",[182,183,184],"Suicide Ideation","Suicidal Behaviors","Depressive Symptoms",[186,187,188,189,190,191,192,193,32,194,195],"Suicidal Ideation","Suicide Attempt","Randomized controlled trial","adolescents","Latinx","Latina","Latino","Hispanic","depressive symptoms","community health workers","2025-03-17",{"date":198,"type":37},"2025-03-19",{"date":200,"type":37},"2024-03-28",{"date":202,"type":21},"2027-01",{"name":43,"class":44},""]