[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Brazilian Institute of Robotic Surgery\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":76},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,45],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":28,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":34,"lastUpdatePostDateStruct":35,"startDateStruct":38,"completionDateStruct":40,"leadSponsor":42,"locationsCount":5},"100607598","comparison-of-outcomes-and-surgical-time-between-cortical-and-medullary-suture-vs-medullary-only-suture-cortex-clinical-trial-100607598",false,"NCT07190638","Comparison of Outcomes and Surgical Time Between Cortical and Medullary Suture vs. Medullary-Only Suture: Cortex Clinical Trial","Comparison of Outcomes and Surgical Time Between Cortical and Medullary Suture vs. Medullary-Only Suture: Cortex Clinical Trial, From 2025 to 2027","CORTEX","Inclusion Criteria:\n\n* Diagnosis of renal mass confirmed by computed tomography (CT) or magnetic resonance imaging (MRI)\n* Indication for partial nephrectomy\n* Written informed consent\n* Expected survival of at least 6 months\n* Eastern Cooperative Oncology Group (ECOG) score performance status ≤ 1\n* Negative serum or urine pregnancy test within 24 hours before surgery for women of childbearing potential\n* Recovery from any prior therapy-related toxicity to grade 1 or better\n* If a biopsy has been performed, pathology consistent with renal cell carcinoma (RCC)\n\nExclusion Criteria:\n\n* Solitary kidney\n* Multiple or bilateral renal masses if more than one mass is operated on simultaneously or within less than 4 months\n* Hepatic or renal toxicity grade ≥ 2 with glomerular filtration rate (GFR) \\\u003C 30 according to Common Terminology Criteria for Adverse Events (CTCAE v4)\n* Bleeding diathesis\n* Inability to maintain anticoagulation for surgery\n* Participation in another experimental trial simultaneously or within 30 days prior to enrollment\n* Significant acute or chronic medical, neurological, or psychiatric condition that could compromise safety, limit study completion, or impair study objectives in the opinion of the Principal Investigator","ALL","18 Years",{"count":20,"type":21},80,"ESTIMATED","INTERVENTIONAL",[24],"NA","Renal function preservation is a growing concern in the surgical management of kidney tumors, particularly with the rise in chronic kidney disease worldwide. Recent surgical innovations have focused on modifying renorrhaphy techniques to minimize renal damage. Emerging evidence suggests that omitting cortical suturing may reduce operative time, blood loss, and renal parenchymal loss without increasing major complications. This randomized controlled trial aims to compare outcomes between medullary-only and combined cortical-medullary suture techniques during robot-assisted partial nephrectomy, with the goal of identifying the approach that best balances functional preservation and surgical safety.",[27],"RCC, Renal Cell Cancer",[29,30,31,32],"Partial Nephrectomy","Robot-assisted","MEDULLARY SUTURE","MEDULLARY-ONLY SUTURE","RECRUITING","2025-09-20",{"date":36,"type":37},"2025-09-24","ACTUAL",{"date":39,"type":37},"2025-07-23",{"date":41,"type":21},"2027-05-31",{"name":43,"class":44},"Brazilian Institute of Robotic Surgery","OTHER",{"id":46,"slug":47,"hasResults":11,"nctId":48,"briefTitle":49,"officialTitle":49,"acronym":50,"eligibilityCriteria":51,"healthyVolunteers":11,"sex":52,"minAge":18,"maxAge":53,"enrollmentInfo":54,"targetDuration":4,"studyType":22,"phases":56,"briefSummary":58,"conditions":59,"keywords":64,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":68,"lastUpdatePostDateStruct":69,"startDateStruct":71,"completionDateStruct":73,"leadSponsor":75,"locationsCount":5},"100576414","phase-4-impact-of-using-the-airseal-system-with-ultra-low-pneumoperitoneum-in-patients-undergoing-robot-assisted-radical-prostatectomy-a-prospective-comparative-randomized-clinical-study-100576414","NCT06784986","Impact of Using the Airseal System With Ultra-low Pneumoperitoneum in Patients Undergoing Robot-assisted Radical Prostatectomy: A Prospective, Comparative, Randomized Clinical Study.","ARCO2","Inclusion Criteria:\n\n* Patients with prostate cancer who will undergo robotic prostatectomy;\n\nExclusion Criteria:\n\n* Patients over 65 and under 18 years of age;\n* Patients allergic to NSAIDs and\u002For Morphine and\u002For Tramadol;\n* Patients with chronic renal failure;\n* Patients with recurrence, metastasis and other existing neoplasms.","MALE","65 Years",{"count":55,"type":21},200,[57],"PHASE4","The AirSeal platform has been evaluated in urological surgeries, mainly in cases of malignant diseases 5,6. However, there is still a lack of data demonstrating the possible benefits of its use, which justifies the conduct of this research in order to aggregate such knowledge. Therefore, the objective of this prospective pilot study is to compare and evaluate the role of low-pressure pneumoperitoneum with the AirSeal system in patients with prostate cancer undergoing robot-assisted prostatectomy with those undergoing the procedure with the conventional insufflation system. We seek to provide more data on the use of AirSeal, which is associated with shorter operative times, shorter hospital stays and a lower probability of complications. In addition, we aim to ratify the effectiveness and cost-benefit of using the AirSeal system.",[60,61,62,63],"Prostate Carcinoma","Prostate Neoplasm","Pain Intensity Assessment","Quality of Life (QOL)",[65,66,67],"pneumoperitoneum","airseal","pneumoperitoneum in prostate neoplasm","2025-01-15",{"date":70,"type":37},"2025-01-20",{"date":72,"type":21},"2025-02",{"date":74,"type":21},"2026-02-15",{"name":43,"class":44},""]