[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"British University In Egypt\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":329},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,13,0,[8,41,67,94,118,141,167,189,218,239,265,288,311],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":15,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":4,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":29,"lastUpdatePostDateStruct":30,"startDateStruct":33,"completionDateStruct":35,"leadSponsor":37,"locationsCount":40},"100643845","khourys-bone-shell-technique-versus-titanium-reinforced-polytetrafluoroethylene-for-augmentation-of-horizontal-deficiency-in-posterior-mandible-histomorphometry-analysis-a-randomized-clinical-trial-100643845",false,"NCT07669792","Khoury's Bone Shell Technique Versus Titanium-Reinforced Polytetrafluoroethylene for Augmentation of Horizontal Deficiency in Posterior Mandible (Histomorphometry Analysis): A Randomized Clinical Trial","Inclusion Criteria:\n\n1. Have two or more missing teeth in the posterior mandibular segment.\n2. The patients age of 18 and above.\n3. The alveolar ridge in the edentulous site of the selected patients will have a buccolingual width of less than 4mm.\n4. Sufficient vertical bone height.\n5. Free of any local or systemic condition that may contraindicate ridge expansion procedure.\n\nExclusion Criteria:\n\n1. Patients taking any medication that may interfere with bone healing or bone biology.\n2. Patients with any systemic disease that may affect bone healing.\n3. Any patients with any previous bone grafting procedure at the site of interest.\n4. Smokers.\n5. Patient's that have been diagnosed with periodontal disease, as sufficient ridge height would be improbable.\n6. Patients with significant vitamin D deficiency.",true,"ALL","18 Years","65 Years",{"count":20,"type":21},16,"ESTIMATED","INTERVENTIONAL",[24],"NA","The purpose of the study is the comparison of bone gained histologically from the Bone Shell Khoury's Technique in comparison with the usage of non-resorbable membrane polytetrafluoroethylene and discussing its eligibility for implant placement in restoring the atrophic posterior mandible.",[27],"Alveolar Bone Loss in Posterior Mandible","RECRUITING","2026-06-21",{"date":31,"type":32},"2026-06-25","ACTUAL",{"date":34,"type":32},"2025-06-20",{"date":36,"type":21},"2027-03",{"name":38,"class":39},"British University In Egypt","OTHER",1,{"id":42,"slug":43,"hasResults":11,"nctId":44,"briefTitle":45,"officialTitle":46,"acronym":4,"eligibilityCriteria":47,"healthyVolunteers":15,"sex":16,"minAge":17,"maxAge":48,"enrollmentInfo":49,"targetDuration":4,"studyType":22,"phases":51,"briefSummary":52,"conditions":53,"keywords":55,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":59,"lastUpdatePostDateStruct":60,"startDateStruct":62,"completionDateStruct":64,"leadSponsor":66,"locationsCount":40},"100630815","evaluation-of-the-magnesium-shield-compared-to-dual-zone-grafting-approach-in-immediate-implant-site-management-100630815","NCT07492576","Evaluation of the Magnesium Shield Compared to Dual Zone Grafting Approach in Immediate Implant Site Management","Evaluation of the Magnesium Shield Compared to Dual Zone Grafting Approach in Immediate Implant Site Management: a Randomized Controlled Clinical Trial","Inclusion Criteria:\n\n* 18-60 years of age\n* Patients have hopeless maxillary teeth, a thin buccal plate of bone ≤1 mm and intact overlying soft tissue intact overlying soft tissues in aesthetic zone (EDS-2, Kan classification)\n* Periodontally healthy (good oral hygiene)\n* Medically controlled patient\n\nExclusion Criteria:\n\n* Smokers\n* patients with systemic diseases\n* history of chemotherapy or radiotherapy within the past 2 years.\n* Acute infection","60 Years",{"count":50,"type":21},22,[24],"Will (GBR) by application of magnesium membrane with immediate implant will have more volume gain , higher pink esthetic score, and lower visual analogue scale than dual zone grafting technique? Several methods have been suggested for the preservation of post-extraction resorption and promoting an increase in the bone density with immediate implant placement. one of these techniques is the dual zone concept (DZ), atraumatic tooth extraction using peristomes and luxators, implant placement along with the bone grafting material applied to both the bone and tissue zones.\n\nThe aim of (DZ) is to augment the soft tissue using a bone graft to avoid mucosal recession after implant placement thus keeping the gingival contour providing optimal soft tissue aesthetic.\n\nThe use of magnesium membrane in combination with inorganic bovine bones will be placed between the membrane and immediate implant. This allows implant placement while simultaneously rehabilitating the entire socket, due to its unique material properties, a magnesium membrane is used to rebuild, support the buccal or oral walls in compromised sockets, and promotes cortical bone growth . Many techniques available for preserving the bone of the socket post-tooth extraction, but in comparison to the current materials and techniques used , magnesium membrane is completely resorbable and does not require second surgery to be removed; it is synthetic and therefore does not need to be sourced from an additional surgical. magnesium membrane is excellent in providing both esthetic and functional outcomes that meet patient expectations.\n\nThe procedure involves flapless approach in which atraumatic tooth extraction using peristomes and forceps will be performed to preserve the available alveolar bone. The implant site will be prepared, and the implant will be placed palatal and 3-4m.m apical to the free gingival margin (FGM). magnesium membrane will be placed between the soft tissue and thin buccal wall. The edges of the membrane will be shaped and flattened with sculptor to prevent perforation of the soft tissue, and a layer off inorganic bovine bone will be placed between the e buccal wall and implant. Then immediate provisional restoration will be constructed and placed to allow an ideal final crown mimicking the natural emergence profile.",[54],"Immediate Implant Placement",[56,57,58],"Magnesium shield ,","Immidate implant","dual zone concept with immediate implant.","2026-03-27",{"date":61,"type":32},"2026-04-01",{"date":63,"type":32},"2026-03-19",{"date":65,"type":21},"2027-01-29",{"name":38,"class":39},{"id":68,"slug":69,"hasResults":11,"nctId":70,"briefTitle":71,"officialTitle":72,"acronym":4,"eligibilityCriteria":73,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":74,"enrollmentInfo":75,"targetDuration":4,"studyType":22,"phases":77,"briefSummary":79,"conditions":80,"keywords":82,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":87,"lastUpdatePostDateStruct":88,"startDateStruct":89,"completionDateStruct":91,"leadSponsor":93,"locationsCount":40},"100628139","early-phase-1-clinical-performance-of-a-novel-self-cured-resin-composite-compared-to-a-light-cured-bioactive-resin-composite-restoration-in-proximal-cavities-of-posterior-teeth-100628139","NCT07457749","Clinical Performance of a Novel Self-cured Resin Composite Compared to a Light-cured Bioactive Resin Composite Restoration in Proximal Cavities of Posterior Teeth","Clinical Performance of a Novel Self-cured Resin Composite Compared to a Light-cured Bioactive Resin Composite Restoration in Proximal Cavities of Posterior Teeth: A 2-year Randomized Controlled Clinical Trial","Inclusion Criteria:\n\n1. Subjects between the ages of 18-47 years old\n2. Primary caries removal\n3. Good or moderate oral hygiene\n4. Free of periodontal diseases (probing depth and attachment levels within normal limits\u002F no furcation involvement\u002F no mobility)\n5. Cooperative patients who agree to keep the scheduled recall appointments for data collection and maintenance\n\nExclusion Criteria:\n\n1. Composite or amalgam removal\n2. Caries extended to the cemento-enamel junction in Class II caries\n3. Grade II or III mobility\n4. Considerable periodontal disease without treatment\n5. Endodontically treated teeth with extensive loss of tooth tissues\n6. Severe wear facets and\u002For parafunctional activities as clenching or nocturnal bruxism.\n7. Subjects who are pregnant during the duration of the study\n8. Subjects with high caries activity","47 Years",{"count":76,"type":21},50,[78],"EARLY_PHASE1","The development of dental caries is multi-factorial mainly due to the presence of 4 elements which are: dental biofilm, fermentable carbohydrates , dental hard tissue and time. Other additional social and environmental factors can have a substantial impact on the onset and course of the disease. Dietary habits, oral hygiene, salivary flow and fluoride exposure are key factors that influence the susceptibility to dental caries. If dental caries is properly managed, it is a preventable and reversible disease. The proximal teeth surfaces are the most susceptible sites for demineralization from the acidic byproducts. In modern restorative dentistry, clinicians always seek solutions that streamline procedures, improve outcomes and reduce chair time for patients. Traditional light-cured composite systems often involve a complex seven step process which includes etching, priming, bonding and curing which consumes from 90 to 120 seconds to be completed. With each additional step, the risk of technique errors increases, potentially compromising the longevity of the restoration. Self-cure composites, with their simplified application process, are emerging as a preferred choice over the traditional seven-step composite materials. Recently, a novel self-cured high-performance bulk-fill restorative material has been introduced into the market (Stela, SDI, Victoria, Australia). It's particularly known for its \"unlimited\" depth of cure and self-adhesive properties.",[81],"Proximal Cavities of Posterior Teeth",[83,84,85,86],"clinical performance","self-cured resin composite","bioactive","proximal cavities","2026-03-17",{"date":63,"type":32},{"date":90,"type":32},"2026-02-18",{"date":92,"type":21},"2028-03-18",{"name":38,"class":39},{"id":95,"slug":96,"hasResults":11,"nctId":97,"briefTitle":98,"officialTitle":98,"acronym":4,"eligibilityCriteria":99,"healthyVolunteers":15,"sex":16,"minAge":17,"maxAge":48,"enrollmentInfo":100,"targetDuration":4,"studyType":22,"phases":102,"briefSummary":103,"conditions":104,"keywords":106,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":110,"lastUpdatePostDateStruct":111,"startDateStruct":113,"completionDateStruct":115,"leadSponsor":117,"locationsCount":40},"100621284","effectiveness-of-connective-tissue-graft-with-and-without-leukocyte-platelet-rich-fibrin-on-peri-implant-soft-tissue-thickness-around-delayed-implants-in-patients-with-thin-gingival-phenotype-a-randomized-controlled-clinical-trial-100621284","NCT07368621","Effectiveness of Connective Tissue Graft With and Without Leukocyte Platelet Rich Fibrin on Peri-implant Soft Tissue Thickness Around Delayed Implants in Patients With Thin Gingival Phenotype: A Randomized Controlled Clinical Trial","Inclusion Criteria:\n\n* 1\\. Patients between 18-60 years. 2. With thin gingival phenotype with a peri-implant mucosal thickness of less than 2mm28. With single missing tooth in the incisor, canine and premolar area. With the presence of two natural adjacent teeth and to not have a bone augmentation procedure before or during the dental implant.\n\n  3\\. Patient consent approval and signing 4. Medically free patients 5. Patients with good oral hygiene 6. Patients free from untreated periodontal disease\n\nExclusion Criteria:\n\n* 1\\. Smokers 2. Psychological problem 3. Pregnancy 4. Systemic disease 5. Poor oral hygiene 6. Patients who previously received radiation therapy of the jaws 7. Patients taking medications that affect healing.",{"count":101,"type":21},38,[24],"A stable soft and hard tissues around Osseo-integrated implants are very crucial. Soft tissue thickness around implants is crucial as it prevents peri-implant bone loss and enhance the esthetic outcomes. The treatment of thin tissue phenotype should be improved as the thin tissue phenotype will lead to plaque accumulation. There are some techniques that can increase the thickness of the peri-implant mucosa including connective tissue graft, platelet- rich fibrin and xenogeneic collagen matrix .Leukocyte and Platelet rich fibrin is a second generation platelet concentrate that was introduced by choukroun et al in 2001 after platelet rich plasma. PRF is the first source of autogenous blood derived growth factors harvested without the use of anticoagulants5. It contains various growth factors that are believed to contribute to periodontal regeneration. It promotes neovascularization and accelerated wound closing",[105],"Soft Tissue Thickness Around Delayed Implants in Patients With Thin Gingival Phenotype",[107,108,109],"CTG","L-Prf","Soft tissue thickness","2026-01-20",{"date":112,"type":32},"2026-01-26",{"date":114,"type":32},"2026-01-16",{"date":116,"type":21},"2026-07-31",{"name":38,"class":39},{"id":119,"slug":120,"hasResults":11,"nctId":121,"briefTitle":122,"officialTitle":123,"acronym":4,"eligibilityCriteria":124,"healthyVolunteers":11,"sex":16,"minAge":4,"maxAge":4,"enrollmentInfo":125,"targetDuration":4,"studyType":22,"phases":127,"briefSummary":130,"conditions":131,"keywords":4,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":133,"lastUpdatePostDateStruct":134,"startDateStruct":136,"completionDateStruct":138,"leadSponsor":140,"locationsCount":40},"100586069","phase-2-oxygenated-gel-therapy-in-the-management-of-oral-aphthous-ulcers-100586069","NCT06910579","Oxygenated Gel Therapy in the Management of Oral Aphthous Ulcers","Efficacy of Oxygenated Gel Therapy in the Management of Oral Aphthous Ulcers: A Randomized Controlled Clinical Trial","Inclusion Criteria:\n\n* Clinically diagnosed patients with chronic aphthous stomatitis measuring ≤6 mm in size in the oral cavity and who gave written consent for participation.\n* Only single ulcers were considered for the study.\n* Systemically healthy patients.\n\nExclusion Criteria:\n\n* The study excluded patients with a history of associated systemic disease.\n* Cases of chronic aphthous stomatitis (major), lesions of herpetic form, numerous aphthae, and smoking.\n* Patients with a history of hypersensitivity to the used agents.\n* Pregnancy and lactation",{"count":126,"type":21},30,[128,129],"PHASE2","PHASE3","Interventions of both groups:\n\nOxygenated gel Group: 15 patients who used oxygenated gel (Blue®m, Wijhe, Netherlands) were trained by the co-investigator (A.H) through real demonstration for topical application of the gel on aphthous ulcers, which entails the application of 1-2 ml of oxygenated gel directly to the ulcer two times per day and this was repeated for 7 days.\n\nTriamcinolone acetonide Group: 15 patients were treated with Kenalog in orabase (Triamcinolone acetonide 0.1% oral paste 5g), four times (i.e., at 8 am, 12 noon, 4 pm, and 8 pm) a day for 7 days at intervention group.\n\nPatients in both groups were reexamined after treatment at different intervals (day 3, day 5, day 7, and day 10).",[132],"Aphthus Ulcer","2025-09-16",{"date":135,"type":32},"2025-09-18",{"date":137,"type":32},"2025-03-15",{"date":139,"type":21},"2026-04-12",{"name":38,"class":39},{"id":142,"slug":143,"hasResults":11,"nctId":144,"briefTitle":145,"officialTitle":146,"acronym":147,"eligibilityCriteria":148,"healthyVolunteers":15,"sex":16,"minAge":17,"maxAge":149,"enrollmentInfo":150,"targetDuration":4,"studyType":22,"phases":152,"briefSummary":153,"conditions":154,"keywords":4,"overallStatus":157,"whyStopped":4,"lastUpdateSubmitDate":158,"lastUpdatePostDateStruct":159,"startDateStruct":161,"completionDateStruct":163,"leadSponsor":165,"locationsCount":166},"100601842","vestibular-versus-trapezoid-flap-in-immediate-implants-100601842","NCT07115758","Vestibular Versus Trapezoid Flap in Immediate Implants","The Impact of Vestibular Versus Trapezoidal Flap Design on Immediate Implants : a Randomized Clinical Trial","VST","Inclusion Criteria:\n\n* Patients having a hopeless maxillary tooth in the esthetic region missing coronal tooth structure, type II socket (deficient labial plate of bone and intact overlying soft tissues), adequate palatal bone, ≥ 3 mm apical bone to engage the immediately placed implants, thereby achieving optimum primary stability (a minimum of 30 Ncm insertion torque) following tooth extraction.\n\nExclusion Criteria:\n\n* Smokers, pregnant women, patients with systemic diseases, and history of chemotherapy or radiotherapy within the past 2 years.","99 Years",{"count":151,"type":21},32,[24],"The vestibular socket therapy was introduced by Elaskary et al that allowed immediate implant placement and total socket rehabilitation at the same time in class 2 compromised sockets , that showed supreme esthetic and functional predictability over 1,2,3 years of follow up, and showed minimal or no post restorative mid facial recession . The Vestibular socket therapy (VST) entails socket augmentation through a minimally invasive vestibular access incision to allow the delivery of the grafting components thus bypass the deleterious effect of the classic mucoperiosteal flap reflection as well as the deleterious effect of the delay approach, regardless of the degree of socket compromise \\[6-8\\].",[155,156],"Immediate Dental Implant Placement","Defect in Alveolar Ridge","NOT_YET_RECRUITING","2025-08-04",{"date":160,"type":32},"2025-08-11",{"date":162,"type":21},"2025-08-15",{"date":164,"type":21},"2026-03-01",{"name":38,"class":39},3,{"id":168,"slug":169,"hasResults":11,"nctId":170,"briefTitle":171,"officialTitle":172,"acronym":147,"eligibilityCriteria":173,"healthyVolunteers":15,"sex":16,"minAge":17,"maxAge":174,"enrollmentInfo":175,"targetDuration":4,"studyType":22,"phases":176,"briefSummary":177,"conditions":178,"keywords":180,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":158,"lastUpdatePostDateStruct":182,"startDateStruct":184,"completionDateStruct":186,"leadSponsor":188,"locationsCount":40},"100597849","management-of-multiple-adjacent-extraction-sockets-100597849","NCT07063836","Management of Multiple Adjacent Extraction Sockets","Management of Compromised Adjacent Extraction Sockets Via Vestibular Socket Therapy Versus Early Contour Augmentation a Randomized Controlled Clinical Trial","Inclusion Criteria:\n\n\\- patients with two adjacent hopeless maxillary teeth or remaining roots in the esthetic region missing coronal tooth structure, type II socket (deficient labial plate of bone and intact overlying soft tissues), adequate palatal bone, ≥ 3 mm apical bone to engage the immediately placed implants, thereby achieving optimum primary stability (a minimum of 30 Ncm insertion torque) following teeth extraction.\n\nacceptable compliance and oral hygiene.\n\nExclusion Criteria:\n\nmedically compromised patients. (Systemic diseases). general contraindication for implant placement. (Untreated periodontitis, severe bruxism , immunosuppression , uncontrolled diabetes , smokers , patients under radiation therapy, patients on bisphosphonate medications).\n\n\\-","70 Years",{"count":151,"type":21},[24],"While early implant placement with guided bone regeneration (GBR) offers advantages, the desire for reduced treatment time and fewer surgical steps continues to drive the exploration of alternative approaches. In this context, the recent introduction of vestibular socket therapy (VST) presents an intriguing option. VST utilizes a minimally invasive tunnel access technique through the vestibular area to perform socket augmentation for immediate implant placement in compromised extraction sockets .",[179],"Dental Implant in Compromised Adjacent Sockets",[181],"dental implant, compromised socket, bone augmentation",{"date":183,"type":32},"2025-08-07",{"date":185,"type":32},"2025-07-14",{"date":187,"type":21},"2026-03",{"name":38,"class":39},{"id":190,"slug":191,"hasResults":11,"nctId":192,"briefTitle":193,"officialTitle":194,"acronym":4,"eligibilityCriteria":195,"healthyVolunteers":15,"sex":16,"minAge":17,"maxAge":196,"enrollmentInfo":197,"targetDuration":4,"studyType":22,"phases":199,"briefSummary":200,"conditions":201,"keywords":205,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":210,"lastUpdatePostDateStruct":211,"startDateStruct":213,"completionDateStruct":215,"leadSponsor":217,"locationsCount":40},"100532011","phase-2-the-antimicrobial-potential-of-diclofenac-sodium-as-an-intracanal-medicament-100532011","NCT06207253","The Antimicrobial Potential of Diclofenac Sodium as an Intracanal Medicament","The Antimicrobial Potential of Diclofenac Sodium as an Intracanal Medicament During Root Canal Treatment: A Randomized Clinical Trial","Inclusion Criteria:\n\n* Patients with teeth diagnosed with apical periodontitis\n* Periapical Index (PAI) ≥ 2\n* The teeth are restorable\n\nExclusion Criteria:\n\n* Teeth with immature roots\n* Non restorable teeth\n* Medically compromised patients with systemic complication that would alter the treatment.\n* Teeth with internal\u002Fexternal root resorption\n* Patient with an allergy to diclofenac sodium","50 Years",{"count":198,"type":21},48,[128,129],"The goal of this randomized clinical trial is to evaluate the capability of the material to exert bacterial reduction of diclofenac sodium versus of that calcium hydroxide paste when these materials are used as intracanal medications in permanent molar teeth with chronic apical periodontitis.\n\nThe main question\\[s\\] it aims to answer are:\n\n• Will the diclofenac sodium (NSAIDs) possess antimicrobial efficacy to be used effectively as an intracanal medicament similar to that of calcium hydroxide in primary endodontic treatment? Participants will be allocated randomly into three equal groups by using computer generated randomization, according to the type of intracanal medication.",[202,203,204],"Endodontic Disease","Pulp Disease, Dental","Intracanal Medication",[206,207,208,209],"Sodium diclofenac","Intracanal medication","Calcium hydroxide","Apical periodontitis","2025-05-26",{"date":212,"type":32},"2025-05-30",{"date":214,"type":21},"2025-11",{"date":216,"type":21},"2025-12",{"name":38,"class":39},{"id":219,"slug":220,"hasResults":11,"nctId":221,"briefTitle":222,"officialTitle":222,"acronym":4,"eligibilityCriteria":223,"healthyVolunteers":15,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":224,"targetDuration":4,"studyType":22,"phases":226,"briefSummary":227,"conditions":228,"keywords":4,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":231,"lastUpdatePostDateStruct":232,"startDateStruct":234,"completionDateStruct":236,"leadSponsor":238,"locationsCount":40},"100567852","assessment-of-the-accuracy-of-complete-crown-3d-superimposition-technique-relative-to-the-gold-standard-technique-for-digital-quantification-of-volumetric-soft-tissue-changes-in-the-esthetic-zone-100567852","NCT06673576","Assessment of The Accuracy of Complete Crown 3D Superimposition Technique Relative to The Gold Standard Technique for Digital Quantification of Volumetric Soft Tissue Changes in The Esthetic Zone","Inclusion Criteria:\n\n1. Patients requiring esthetic crown lengthening.\n2. Full-mouth plaque and bleeding score not exceeding 20%.\n3. Presence of at least 2.5 mm keratinized tissue width (Pontoriero \\& Carnevale, 2001).\n4. Patients showing motivation to comply with post-operative care instructions and follow-up appointments.\n\nExclusion Criteria:\n\n* 1\\. Systemic health conditions that contraindicate or affect healing of periodontal surgery.\n\n  2\\. Patients requiring prosthetic crowns or restorations in the esthetic zone. 3. Gummy smile with normal tooth proportions. 4. Patients treated with medications known to affect the gingiva (Phenytoin, Cyclosporine and Nifedipine).\n\n  5\\. Smokers. 6. Pregnant and nursing females.",{"count":225,"type":21},12,[24],"The aim of this study is to assess the precision of the complete crown technique employed for the superimposition of 3D models, specifically in the quantitative volumetric evaluation of gingival tissues. This technique was initially introduced in an in-vitro study by Dritsas et al. (2023) as a means to achieve an accurate, reproducible, and simple method for quantification of gingival recession.\n\nThis study will involve the analysis of digital models in. ply format acquired through intraoral scanning of patients scheduled for esthetic crown lengthening, with predefined inclusion and exclusion",[229,230],"Volume Assessment","Gummy Smile","2024-11-02",{"date":233,"type":32},"2024-11-05",{"date":235,"type":32},"2024-03-15",{"date":237,"type":21},"2025-05-15",{"name":38,"class":39},{"id":240,"slug":241,"hasResults":11,"nctId":242,"briefTitle":243,"officialTitle":244,"acronym":4,"eligibilityCriteria":245,"healthyVolunteers":15,"sex":16,"minAge":246,"maxAge":247,"enrollmentInfo":248,"targetDuration":4,"studyType":22,"phases":249,"briefSummary":250,"conditions":251,"keywords":253,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":256,"lastUpdatePostDateStruct":257,"startDateStruct":259,"completionDateStruct":261,"leadSponsor":263,"locationsCount":264},"100560773","custom-made-zirconia-crowns-and-3d-printed-resin-crowns-versus-ready-made-zirconia-crowns-in-primary-molars-100560773","NCT06581510","Custom-Made Zirconia Crowns and 3D-Printed Resin Crowns Versus Ready-Made Zirconia Crowns in Primary Molars","Custom-Made Zirconia Crowns and 3D Printed Resin Crowns Versus Ready-Made Zirconia Crowns in Primary Molars: A Randomized Controlled Trial","Inclusion Criteria:\n\n* Healthy children within age range of 5-8 years old\n* Upper and lower primary second molars\n* Vital primary second molars\n* Cooperative children Frankl scale 3 (positive) and 4 (definitely positive)\n\nExclusion Criteria:\n\n* Radiographic radiolucency related to the furcation and periapical area or any evidence of root resorption\n* Deep bite\n* More than 2 walls lost due to caries\n* Presence of parafunctional habits","5 Years","8 Years",{"count":126,"type":21},[24],"The main problem introduced in this study is the aggressive reduction needed for ready-made zirconia crowns to be passively fitted. In addition, its relatively expensive cost and wear of the opposing tooth structure. In this study, different crown materials will be introduced, such as customized zirconia crowns and novel 3D printed resin crowns who may offer better adaptability and gingival health and are relatively cost effective. The proposed study will help in increasing studies of different crown materials for primary teeth",[252],"Dental Crowns",[254,255],"pediatric esthetic crowns","posterior esthetic crowns","2024-08-30",{"date":258,"type":32},"2024-09-03",{"date":260,"type":32},"2024-02-25",{"date":262,"type":21},"2026-02-23",{"name":38,"class":39},2,{"id":266,"slug":267,"hasResults":11,"nctId":268,"briefTitle":269,"officialTitle":270,"acronym":4,"eligibilityCriteria":271,"healthyVolunteers":15,"sex":16,"minAge":272,"maxAge":273,"enrollmentInfo":274,"targetDuration":4,"studyType":22,"phases":276,"briefSummary":277,"conditions":278,"keywords":279,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":281,"lastUpdatePostDateStruct":282,"startDateStruct":284,"completionDateStruct":286,"leadSponsor":287,"locationsCount":40},"100531186","phase-2-anti-bacterial-potential-of-nano-calcium-hydroxide-as-an-intracanal-medication-100531186","NCT06196515","Anti-bacterial Potential of Nano Calcium Hydroxide as an Intracanal Medication","Evaluation of the Antibacterial Potential of Nano Calcium Hydroxide as an Intracanal Medication: A Randomized Clinical Trial","Inclusion Criteria:\n\n* healthy males and females.\n* age range between 21-49.\n* patients with no physical disability or psychological problems.\n* patients presenting with single permanent molar with signs and\u002For symptoms of apical periodontitis, and having Periapican index ≥ 2.\n\nExclusion Criteria:\n\n* pregnant women.\n* patients with immune-compromised disease.\n* patients with complicated systemic diseases.\n* patients who took antibiotics within a period of 1 month.\n* patients with known sensitivity to the medicaments or pharmaceuticals used in this study.\n* Non-restorable teeth including root fractures, and\u002For advanced periodontal involvement.","21 Years","49 Years",{"count":275,"type":21},54,[128,129],"The aim of the study is to evaluate the anti-bacterial potential of Nano Calcium Hydroxide as an intracanal medication in primary endodontic treatment of permanent molars.",[202,203],[280],"intracanal medication","2024-08-16",{"date":283,"type":32},"2024-08-19",{"date":285,"type":21},"2024-08",{"date":216,"type":21},{"name":38,"class":39},{"id":289,"slug":290,"hasResults":11,"nctId":291,"briefTitle":292,"officialTitle":293,"acronym":4,"eligibilityCriteria":294,"healthyVolunteers":15,"sex":16,"minAge":17,"maxAge":196,"enrollmentInfo":295,"targetDuration":4,"studyType":22,"phases":296,"briefSummary":297,"conditions":298,"keywords":4,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":303,"lastUpdatePostDateStruct":304,"startDateStruct":306,"completionDateStruct":308,"leadSponsor":310,"locationsCount":40},"100503901","the-incidence-of-postoperative-pain-after-using-different-types-of-sealers-100503901","NCT05841290","The Incidence of Postoperative Pain After Using Different Types of Sealers","The Incidence of Postoperative Pain After Using Different Types of Sealers (A Randomized Clinical Trial)","Inclusion Criteria:\n\n* • Patient's age ranges from 18-50 years old.\n\n  * Patients with teeth diagnosed with symptomatic irreversible pulpitis.\n  * Normal periapical condition confirmed by normal periapical radiograph\n  * The teeth are restorable\n  * Teeth are periodontally free, with no mobility and negative to percussion and palpation test.\n\nExclusion Criteria:\n\n* • Teeth with immature roots\n\n  * Non restorable teeth\n  * Medically compromised patients with systemic complication that would alter the treatment.\n  * Necrotic teeth\n  * Teeth with apical periodontitis or periapical lesions\n  * necrotic Teeth.",{"count":76,"type":21},[24],"The aim of this randomized clinical trial is to evaluate and compare the incidence and intensity of post-operative pain after obturation using resin and silicon-based sealers.",[299,300,301,302],"Post Operative Pain","Root Canal Sealers","Sillicon Based Sealers","Resin Based Sealers","2024-07-05",{"date":305,"type":32},"2024-07-08",{"date":307,"type":32},"2022-08-01",{"date":309,"type":21},"2024-10",{"name":38,"class":39},{"id":312,"slug":313,"hasResults":11,"nctId":314,"briefTitle":222,"officialTitle":222,"acronym":4,"eligibilityCriteria":315,"healthyVolunteers":15,"sex":16,"minAge":17,"maxAge":48,"enrollmentInfo":316,"targetDuration":4,"studyType":22,"phases":317,"briefSummary":318,"conditions":319,"keywords":4,"overallStatus":157,"whyStopped":4,"lastUpdateSubmitDate":321,"lastUpdatePostDateStruct":322,"startDateStruct":324,"completionDateStruct":326,"leadSponsor":328,"locationsCount":40},"100551252","assessment-of-the-accuracy-of-complete-crown-3d-superimposition-technique-relative-to-the-gold-standard-technique-for-digital-quantification-of-volumetric-soft-tissue-changes-in-the-esthetic-zone-100551252","NCT06457672","Inclusion Criteria:\n\n1. Patients aged 18 years or older.\n2. Patients requiring esthetic crown lengthening.\n3. Full-mouth plaque and bleeding score not exceeding 20%.\n4. Presence of at least 2.5 mm keratinized tissue width (Pontoriero \\& Carnevale, 2001).\n5. Patients showing motivation to comply with post-operative care instructions and follow-up appointments.\n\nExclusion Criteria:\n\n1. Systemic health conditions that contraindicate or affect healing of periodontal surgery.\n2. Patients requiring prosthetic crowns or restorations in the esthetic zone.\n3. Gummy smile with normal tooth proportions.\n4. Patients treated with medications known to affect the gingiva (Phenytoin, Cyclosporine and Nifedipine).\n5. Smokers.\n6. Pregnant and nursing females.",{"count":225,"type":21},[24],"The aim of this study is to assess the precision of the complete crown technique employed for the superimposition of 3D models, specifically in the quantitative volumetric evaluation of gingival tissues. This technique was initially introduced in an in-vitro study by Dritsas et al. (2023) as a means to achieve an accurate, reproducible, and simple method for quantification of gingival recession.",[320],"Gingival Recession","2024-06-09",{"date":323,"type":32},"2024-06-13",{"date":325,"type":21},"2024-06-15",{"date":327,"type":21},"2024-12-30",{"name":38,"class":39},""]