[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Brunel University\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":90},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,44,67],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":15,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":27,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":32,"lastUpdatePostDateStruct":33,"startDateStruct":36,"completionDateStruct":38,"leadSponsor":40,"locationsCount":43},"100644675","muscle-function-response-to-resistance-band-training-in-older-adults-with-impaired-muscle-power-100644675",false,"NCT07672834","Muscle Function Response to Resistance Band Training in Older Adults With Impaired Muscle Power","Inclusion Criteria:\n\n* Participants will be of male or female sex and free from known neurological health conditions (e.g. Peripheral Neuropathy, Parkinson's Disease, Stroke, Migraines, Epilepsy) or musculoskeletal injury.\n* low muscle power determined as a score of 8.1 and 9 seconds or more for the completion of the 5 times sit to stand test for males and females respectively\n\nExclusion Criteria:\n\n* Neurological health condition or musculoskeletal injury at the time of baseline testing\n* individuals aged under 50\n* individuals who have been told to avoid strenuous physical activity",true,"ALL","50 Years",{"count":19,"type":20},104,"ESTIMATED","INTERVENTIONAL",[23],"NA","To investigate the effect of an fitness advice and resistance band exercise intervention on balance, muscle function, and power in an older people population who have low muscle power.",[26],"Ageing",[28,29,30],"muscle power","Balance","functional movement","RECRUITING","2026-06-29",{"date":34,"type":35},"2026-07-01","ACTUAL",{"date":37,"type":35},"2024-06-02",{"date":39,"type":20},"2027-10-30",{"name":41,"class":42},"Brunel University","OTHER",1,{"id":45,"slug":46,"hasResults":11,"nctId":47,"briefTitle":48,"officialTitle":49,"acronym":4,"eligibilityCriteria":50,"healthyVolunteers":15,"sex":16,"minAge":51,"maxAge":4,"enrollmentInfo":52,"targetDuration":4,"studyType":54,"phases":4,"briefSummary":55,"conditions":56,"keywords":4,"overallStatus":58,"whyStopped":4,"lastUpdateSubmitDate":59,"lastUpdatePostDateStruct":60,"startDateStruct":62,"completionDateStruct":64,"leadSponsor":66,"locationsCount":43},"100627477","physical-activity-intervention-for-mps-100627477","NCT07449143","Physical Activity Intervention for MPS","Co-design of a Physical Activity and Sedentary Behaviour Intervention for Adults With Mucopolysaccharidosis","Adults with Mucopolysaccharidosis will be eligible to participate in the study if they meet the following inclusion criteria:\n\n* Diagnosed with any type of Mucopolysaccharidosis.\n* Aged ≥ 18 years old.\n* Lives in the United Kingdom.\n* Deemed safe to participate by a clinician (for participatory workshops).\n\nExclusion criteria for all participants will be as follows:\n\n* Incapacity to provide informed consent.\n* A level of intellectual disability that would prevent the individual from making a meaningful contribution to the focus groups or workshops.\n* Unable to communicate in English to a sufficient level to permit engagement in the study.\n\nThe circumstances in which an individual may be deemed ineligible to take part in the participatory workshops based on the clinician's assessment are as follows:\n\n* Severe joint pain.\n* Neurological compromise.\n* Stage 4 heart failure or other condition resulting in breathlessness to a level they cannot participate.\n* Other clinical condition which dominates the clinical picture to the extent that it dominates the symptoms and influences the findings (e.g. stroke).\n\nSpecialist stakeholders will be members of staff at NHS specialist centres for Mucopolysaccharidosis who are directly involved in healthcare provision to the target population.\n\nLay specialist stakeholders will be individuals who have been involved in supporting adults with Mucopolysaccharidosis, such as family, friends, and members of staff and volunteers at the Society for Mucopolysaccharide Diseases.","18 Years",{"count":53,"type":20},50,"OBSERVATIONAL","Currently, treatments for mucopolysaccharidoses (MPS) are pharmacological and predominantly focus on the physical symptoms of the disease. In the general population and individuals with disabilities, increasing physical activity levels and reducing sedentary time can be an effective, non-pharmacological treatment to improve mental health and quality of life. Such interventions have not yet been developed or evaluated in people with MPS.\n\nThe aim of this study is to co-design a physical activity and sedentary behaviour intervention tailored to the needs of adults with MPS. The study will seek to gain the expertise of adults with MPS, specialist stakeholders (physicians and clinical nurse specialists) and lay specialist stakeholders (family and friends of adults with MPS and members of staff and volunteers at the Society for Mucopolysaccharide Diseases). A range of views and experiences of physical activity and sedentary behaviour will be explored via focus groups (with individuals with MPS and lay specialist stakeholders) and semi-structured interviews (with specialist stakeholders). The information gathered from the focus groups and interviews will then be utilised to inform participatory workshops (with individuals with MPS) to test intervention concepts. Data from these activities will inform the design of a future intervention.",[57],"Mucopolysaccharidosis (MPS)","NOT_YET_RECRUITING","2026-02-27",{"date":61,"type":35},"2026-03-04",{"date":63,"type":20},"2026-03-09",{"date":65,"type":20},"2026-09-30",{"name":41,"class":42},{"id":68,"slug":69,"hasResults":11,"nctId":70,"briefTitle":71,"officialTitle":72,"acronym":4,"eligibilityCriteria":73,"healthyVolunteers":15,"sex":16,"minAge":51,"maxAge":74,"enrollmentInfo":75,"targetDuration":4,"studyType":21,"phases":77,"briefSummary":79,"conditions":80,"keywords":4,"overallStatus":58,"whyStopped":4,"lastUpdateSubmitDate":82,"lastUpdatePostDateStruct":83,"startDateStruct":85,"completionDateStruct":87,"leadSponsor":89,"locationsCount":4},"100555827","early-phase-1-cooling-via-cryogenx-body-cooling-device-100555827","NCT06517147","Cooling Via Cryogenx Body Cooling Device","Efficacy of Post Exercise Heat Stress Cooling Via Cyrogenx Body Cooling Device","The inclusion criteria are:\n\nAged 18 - 40 years Free from known injury, illness and disease and regular use of medications other than oral contraceptives Undertake exercise training \\>3 times per week for \\~30 minutes per session\n\nThe exclusion criteria are:\n\nPregnant Previous history of neuromuscular fatigue Previous history of heat intolerance","40 Years",{"count":76,"type":20},12,[78],"EARLY_PHASE1","The aim of this project is to test the rate of cooling following exercise in the heat utilising the CRYOGENX Cryosuit device i) against passive cooling, and ii) to quantify the rate of cooling and compare this rate with established cooling intervention thresholds i.e. -0.11 to 0.15°C.min-1. As this project is to determine the efficacy of the intervention in populations equivalent to sporting and military personnel, these aims will be tested in young (18-40 year old) healthy male and female participants whom participate in regular physical activity. As a commercially funded project, the experimental design implemented will closely replicate that of the independent investigation into the efficacy of the CAERvest® device.",[81],"Body Temperature Changes","2024-07-18",{"date":84,"type":35},"2024-07-24",{"date":86,"type":20},"2024-09-01",{"date":88,"type":20},"2025-07-31",{"name":41,"class":42},""]