[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Burapha University\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":69},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,42],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":4,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":30,"lastUpdatePostDateStruct":31,"startDateStruct":34,"completionDateStruct":36,"leadSponsor":38,"locationsCount":41},"100637298","effects-of-calamansi-on-blood-glucose-and-insulin-levels-100637298",false,"NCT07587905","Effects of Calamansi on Blood Glucose and Insulin Levels","The Effects of Calamansi (Citrus x Macrocarpa Bunge) Supplementation on Blood Glucose and Insulin Levels in Healthy Volunteers","Inclusion Criteria:\n\n* Healthy individuals who have not been diagnosed with diabetes or prediabetes, with a fasting blood glucose level (after 8 hours of fasting) of less than 100 mg\u002FdL.\n* Aged between 18-30 years, both male and female\n* Body Mass Index (BMI) between 18.5 and 22.9 kg\u002Fm²\n* No diseases affecting blood sugar levels, such as liver or pancreatic diseases\n\nExclusion Criteria:\n\n* Pregnant or breastfeeding women\n* Regular smokers\n* Regular alcohol consumers\n* Individuals with a history of allergies to citrus fruits or citrus-derived ingredients\n* Individuals taking medications that affect glucose metabolism and fat distribution in the body, including steroids, protease inhibitors, and psychiatric medications. These refer to drugs that act on the central nervous system and may affect blood sugar levels or energy metabolism, such as antidepressants, antipsychotics, and mood stabilizers.",true,"ALL","18 Years","30 Years",{"count":21,"type":22},54,"ESTIMATED","INTERVENTIONAL",[25],"NA","Fifty-four healthy sedentary male and female participants aged 18-30 years will be recruited for this study. Participants will be randomly assigned to one of two groups: a control group receiving placebo MMC capsules (n = 27) or a calamansi capsule supplementation group (n = 27). All participants will undergo health screening procedures, including medical history assessment, mental health questionnaire evaluation, and measurements of vital signs, height, body weight, and body composition. Venous blood samples will subsequently be collected to determine blood glucose, insulin, creatinine, alanine aminotransferase (ALT), and malondialdehyde (MDA) levels. These assessments will be performed at three time points: 1) before capsule supplementation (baseline), 2) following a single dose of capsule supplementation, and 3) after 12 weeks of supplementation.",[28],"Calamansi Powder Capsule Supplementation","RECRUITING","2026-05-13",{"date":32,"type":33},"2026-05-15","ACTUAL",{"date":35,"type":33},"2026-05-01",{"date":37,"type":22},"2027-01-31",{"name":39,"class":40},"Burapha University","OTHER",1,{"id":43,"slug":44,"hasResults":11,"nctId":45,"briefTitle":46,"officialTitle":47,"acronym":4,"eligibilityCriteria":48,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":49,"enrollmentInfo":50,"targetDuration":4,"studyType":23,"phases":52,"briefSummary":53,"conditions":54,"keywords":57,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":61,"lastUpdatePostDateStruct":62,"startDateStruct":64,"completionDateStruct":66,"leadSponsor":68,"locationsCount":41},"100594337","expression-of-genes-relating-hypertension-and-efficacy-of-4-7-8-breathing-control-on-reducing-blood-pressure-100594337","NCT07018128","Expression of Genes Relating Hypertension and Efficacy of 4-7-8 Breathing Control on Reducing Blood Pressure","Expression of Genes Relating Hypertension in Thailand and the Efficacy of 4-7-8 Breathing Control on Reducing Blood Pressure in Individuals With Hypertension","Study 1:\n\n1. Group of individuals with hypertension\n\n   Inclusion Criteria:\n   * Male or female\n   * Aged between 18-59 years\n   * Of Thai ethnicity\n   * Diagnosed with hypertension, defined as having an SBP of 140 mmHg or higher, or a DBP of 90 mmHg or higher, or having previously been diagnosed with hypertension and currently taking antihypertensive medication\n   * Originally from various regions of Thailand and currently residing in the eastern region\n\n   Exclusion Criteria:\n   * Has heart disease, such as valvular stenosis or regurgitation, coronary artery disease, or heart failure\n   * Has obesity, defined as having a body mass index (BMI) of 30 kg\u002Fm² or higher\n   * Has a fever or is currently experiencing an infectious disease, such as COVID-19, the flu, or other infections\n2. Group of individuals with normal blood pressure\n\nInclusion Criteria:\n\n* Male or female\n* Aged between 18-59 years\n* Of Thai ethnicity\n* Does not have hypertension, defined as having an SBP below 130 mmHg and a DBP below 85 mmHg, with no prior diagnosis of hypertension and no history of taking antihypertensive medication\n* Originally from various regions of Thailand and currently residing in the eastern region\n\nExclusion Criteria:\n\n* Has heart disease, such as valvular stenosis or regurgitation, coronary artery disease, or heart failure\n* Has obesity, defined as having a body mass index (BMI) of 30 kg\u002Fm² or higher\n* Has a fever or is currently experiencing an infectious disease, such as COVID-19, the flu, or other infections\n\nStudy 2:\n\nInclusion Criteria:\n\n* Male or female, aged 35-59 years\n* Diagnosed with hypertension, with blood pressure levels above the normal range, defined as SBP of 130 mmHg or higher, or DBP of 85 mmHg or higher, and currently taking medication\n* Originally from various regions of Thailand and currently residing in the eastern region\n* Able to communicate effectively\n\nExclusion Criteria:\n\n* Has respiratory diseases, cardiovascular diseases, cerebrovascular disease, kidney disease, cancer, or immune-related conditions such as allergies, autoimmune diseases (e.g., SLE), immunodeficiency, or rheumatoid arthritis\n* Is obese, defined as having a body mass index (BMI) of 30 kg\u002Fm² or higher\n* Has a fever or is currently infected, such as with COVID-19, the flu, or other infectious diseases\n* Is currently pregnant, breastfeeding, or has a history of pregnancy within the 6 months prior to participating in the study","59 Years",{"count":51,"type":22},200,[25],"This study consists of two sub-studies. Study 1 investigates gene expression related to the development of hypertension in Thailand, and Study 2 examines the effectiveness of the 4-7-8 breathing technique in reducing blood pressure in individuals with hypertension.",[55,56],"Genetic Predisposition to Disease","Breathing, Mouth",[58,59,60],"Gene","Blood pressure","Breathing","2026-05-08",{"date":63,"type":33},"2026-05-11",{"date":65,"type":33},"2024-10-01",{"date":67,"type":22},"2026-09-30",{"name":39,"class":40},""]