[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Burke Medical Research Institute\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":106},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,51,82],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":11,"sex":15,"minAge":16,"maxAge":17,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":31,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":39,"lastUpdatePostDateStruct":40,"startDateStruct":43,"completionDateStruct":45,"leadSponsor":47,"locationsCount":50},"100316689","tdcs-and-bimanual-therapy-for-children-with-hemiplegic-cerebral-palsy-100316689",false,"NCT03402854","tDCS and Bimanual Therapy for Children With Hemiplegic Cerebral Palsy","Inclusion Criteria:\n\n* Diagnosis of congenital hemiplegic cerebral palsy\n* Ability to lift and grasp light objects with affected hand\n* Ability to extend wrist of affected hand 15 degrees\n* Ability to follow instructions and provide informed assent\n* Parent(s) able to provide informed consent\n\nExclusion Criteria:\n\n* Seizures after age 2 years\n* Spasticity medication within 6 months before study\n* Selective dorsal rhizotomy\n* Surgery in affected upper extremity within year before study","ALL","6 Years","18 Years",{"count":19,"type":20},80,"ESTIMATED","INTERVENTIONAL",[23],"NA","The goal of this study is to test the efficacy of transcranial direct current stimulation combined with bimanual training on hand function in children with unilateral spastic cerebral palsy (USCP). Children who enroll in the protocol will be randomized to receive either sham (not stimulating) tDCS plus bimanual training, or active (stimulating) tDCS plus bimanual training.",[26,27,28,29,30],"Cerebral Palsy","Hemiplegic Cerebral Palsy","Spastic Hemiplegic Cerebral Palsy","Spastic Hemiparesis","Spastic Hemiplegia",[32,33,34,35,36,37],"pediatric","children","non-invasive brain stimulation","transcranial direct current stimulation","bimanual training","hand training","RECRUITING","2024-07-15",{"date":41,"type":42},"2024-07-16","ACTUAL",{"date":44,"type":42},"2019-12-01",{"date":46,"type":20},"2025-08-31",{"name":48,"class":49},"Burke Medical Research Institute","OTHER",1,{"id":52,"slug":53,"hasResults":11,"nctId":54,"briefTitle":55,"officialTitle":55,"acronym":4,"eligibilityCriteria":56,"healthyVolunteers":57,"sex":15,"minAge":58,"maxAge":59,"enrollmentInfo":60,"targetDuration":4,"studyType":21,"phases":62,"briefSummary":64,"conditions":65,"keywords":67,"overallStatus":73,"whyStopped":4,"lastUpdateSubmitDate":74,"lastUpdatePostDateStruct":75,"startDateStruct":77,"completionDateStruct":79,"leadSponsor":81,"locationsCount":50},"100536631","early-phase-1-effects-of-transcranial-random-noise-stimulation-on-motor-learning-in-typically-developing-adolescents-100536631","NCT06267339","Effects of Transcranial Random Noise Stimulation on Motor Learning in Typically Developing Adolescents","Inclusion Criteria:\n\n* Age 10-17 years\n* Ability to follow two-step instructions\n* Provides informed consent\n\nExclusion Criteria:\n\n* Presence of illness, disease",true,"10 Years","17 Years",{"count":61,"type":20},40,[63],"EARLY_PHASE1","The goal of this study is to compare motor learning rates on two different tasks, when combined with non-invasive brain stimulation.",[66],"Children",[68,69,70,71,72],"typically developing children","motor learning","controls","grasp","reach","NOT_YET_RECRUITING","2024-02-12",{"date":76,"type":42},"2024-02-20",{"date":78,"type":20},"2024-09-01",{"date":80,"type":20},"2026-08-31",{"name":48,"class":49},{"id":83,"slug":84,"hasResults":11,"nctId":85,"briefTitle":86,"officialTitle":86,"acronym":87,"eligibilityCriteria":88,"healthyVolunteers":57,"sex":15,"minAge":17,"maxAge":4,"enrollmentInfo":89,"targetDuration":4,"studyType":21,"phases":91,"briefSummary":92,"conditions":93,"keywords":95,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":98,"lastUpdatePostDateStruct":99,"startDateStruct":101,"completionDateStruct":103,"leadSponsor":105,"locationsCount":50},"100483130","operant-conditioning-of-the-soleus-stretch-reflex-in-adults-with-cerebral-palsy-100483130","NCT05571033","Operant Conditioning of the Soleus Stretch Reflex in Adults With Cerebral Palsy","SRC-CP","Inclusion Criteria:\n\n1. Age 18 and above\n2. Diagnosis of spastic Cerebral Palsy\n3. Gross Motor Function Classification System level I-III\n4. Stable medical background\n5. Current medication will remain unchanged for 3 months\n6. Provides informed consent\n7. can walk at least 10 meters with or without assistive device\n8. meets minimum study procedure requirements (elicitation of H-reflex).\n\nExclusion Criteria:\n\n1. Pregnancy\n2. uncontrolled diabetes\n3. weak dorsiflexion\n4. History of cardiac conditions\n5. cognitive deficits that interfere with study procedure and steps for completion\n6. Botox within 2 months of the study\n7. H\u002FO ankle surgeries in affected leg (Dorsal root rhizotomy etc.)\n8. regular use of electrical stimulation to lower extremity muscles\n9. Cochlear or metal implantations on body\n10. No history of seizure after age 2 years\n11. Current use of antiseizure medicines\n12. Any metal or magnetic components in the head (surgical clips, metal work etc.)\n13. Implanted device or cardiac pacemakers (applicable for DS8R too)\n14. Skin disorders\n15. Damaged skin (wounds, broken skin, or recent scar tissue)\n16. Allergy to latex (tape)",{"count":90,"type":20},12,[23],"12 adults with spastic CP will complete 6 baseline sessions and 24 down conditioning sessions held 3 times\u002Fweek. All clinical and physiological assessments collected at baseline will be reassessed after study completion, and follow ups after 2 weeks, 1 month and 3 months. The soleus H reflex (electric analogue of the stretch reflex) will be elicited in all sessions. In each session, participants will complete 20 baseline trials and 225 down conditioning trials to decrease the magnitude of the H-Reflex.",[26,94],"Spastic Cerebral Palsy",[96,97],"Hoffman Reflex","Spinal Reflex Conditioning","2023-09-25",{"date":100,"type":42},"2023-09-26",{"date":102,"type":42},"2022-09-30",{"date":104,"type":20},"2026-12-31",{"name":48,"class":49},""]