[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Bursa Sevket Yilmaz Training and Research Hospital\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":161},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,5,0,[8,47,75,101,129],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":23,"conditions":24,"keywords":28,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":35,"lastUpdatePostDateStruct":36,"startDateStruct":39,"completionDateStruct":41,"leadSponsor":43,"locationsCount":46},"100637778","preoperative-fasting-duration-and-gastric-residue-in-pediatric-upper-gastrointestinal-endoscopy-100637778",false,"NCT07614919","Preoperative Fasting Duration and Gastric Residue in Pediatric Upper Gastrointestinal Endoscopy","Evaluation of Preoperative Fasting Duration and Gastric Residue in Children Undergoing Upper Gastrointestinal Endoscopy for Gastrointestinal Symptoms or Pathology","Inclusion Criteria:\n\n* Pediatric patients aged under 18 years\n* Patients who underwent upper gastrointestinal endoscopy for gastrointestinal symptoms or pathology\n* Patients with available hospital records, anesthesia records, and endoscopy reports\n* Patients with documented preoperative fasting duration\n* Patients with documented endoscopic assessment of gastric residue\n\nExclusion Criteria:\n\n* Patients aged 18 years or older\n* Patients with missing or incomplete data for key study variables\n* Patients without documented preoperative fasting duration\n* Patients without documented gastric residue assessment during endoscopy\n* Duplicate endoscopy records from the same patient, if only the first eligible procedure is included","ALL","0 Years","17 Years",{"count":20,"type":21},110,"ESTIMATED","OBSERVATIONAL","This retrospective observational study aims to evaluate the relationship between preoperative fasting duration and gastric residue in pediatric patients undergoing upper gastrointestinal endoscopy for gastrointestinal symptoms or pathology. The study will assess the associations between gastric residue, gastrointestinal symptoms, underlying gastrointestinal diseases, and endoscopic findings. Data will be retrospectively collected from hospital records, anesthesia records, and endoscopy reports to investigate whether prolonged fasting duration reliably predicts an empty stomach in pediatric gastrointestinal patients.",[25,26,27],"Gastric Residue","Preoperative Fasting","Upper Gastrointestinal Endoscopy",[29,30,31,32,33],"Fasting","Endoscopy, Gastrointestinal","Gastric Emptying","Pediatrics","Anesthesia","NOT_YET_RECRUITING","2026-05-22",{"date":37,"type":38},"2026-05-29","ACTUAL",{"date":40,"type":21},"2026-06-01",{"date":42,"type":21},"2026-07-01",{"name":44,"class":45},"Bursa Sevket Yilmaz Training and Research Hospital","OTHER_GOV",1,{"id":48,"slug":49,"hasResults":11,"nctId":50,"briefTitle":51,"officialTitle":52,"acronym":4,"eligibilityCriteria":53,"healthyVolunteers":11,"sex":16,"minAge":54,"maxAge":4,"enrollmentInfo":55,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":57,"conditions":58,"keywords":63,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":68,"lastUpdatePostDateStruct":69,"startDateStruct":71,"completionDateStruct":73,"leadSponsor":74,"locationsCount":46},"100640251","trajectory-based-phenotyping-after-coronary-artery-bypass-surgery-100640251","NCT07598682","Trajectory-Based Phenotyping After Coronary Artery Bypass Surgery","Early Postoperative Trajectory-Based Phenotyping Improves Risk Stratification Beyond EuroSCORE in Patients Undergoing Coronary Artery Bypass Grafting","Inclusion Criteria:\n\n* Adult patients aged 18 years or older\n* Patients who underwent elective on-pump coronary artery bypass grafting\n* Patients operated between January 1, 2022 and December 31, 2025\n* Patients with available perioperative clinical and laboratory data required for analysis\n\nExclusion Criteria:\n\n* Patients undergoing emergency surgery\n* Patients undergoing concomitant valve surgery\n* Patients with missing or inconsistent key clinical or laboratory data","18 Years",{"count":56,"type":21},1000,"Coronary artery bypass grafting is a commonly performed heart surgery, but patients may have different risks for postoperative complications even when their preoperative risk scores are similar. EuroSCORE II is widely used to estimate surgical risk before cardiac surgery, but it may not fully reflect how the body responds during the early postoperative period.\n\nThis retrospective observational study will evaluate adult patients who underwent elective coronary artery bypass grafting with cardiopulmonary bypass between January 1, 2022 and December 31, 2025. The study will use existing hospital records and laboratory data. No additional treatment, test, or intervention will be given to patients as part of this study.\n\nThe main aim is to examine whether early postoperative changes in inflammatory and renal laboratory markers can identify different patient subgroups, called phenotypes. These markers include neutrophil-to-lymphocyte ratio, systemic immune-inflammation index, triglyceride-glucose index, and serum creatinine. The study will evaluate whether these phenotype groups are associated with postoperative acute kidney injury and prolonged intensive care unit stay.\n\nThe study will also assess whether this early postoperative phenotype-based classification provides additional risk information beyond EuroSCORE II.",[59,60,61,62],"Coronary Artery Bypass Grafting","Postoperative Acute Kidney Injury","Postoperative Complications","Risk Stratification",[64,65,66,67],"Coronary artery bypass grafting","Postoperative phenotyping","EuroSCORE II","Risk stratification","2026-05-13",{"date":70,"type":38},"2026-05-20",{"date":72,"type":21},"2026-05-07",{"date":42,"type":21},{"name":44,"class":45},{"id":76,"slug":77,"hasResults":11,"nctId":78,"briefTitle":79,"officialTitle":80,"acronym":4,"eligibilityCriteria":81,"healthyVolunteers":11,"sex":16,"minAge":4,"maxAge":82,"enrollmentInfo":83,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":85,"conditions":86,"keywords":89,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":93,"lastUpdatePostDateStruct":94,"startDateStruct":96,"completionDateStruct":98,"leadSponsor":100,"locationsCount":46},"100623288","ultrasonographic-subglottic-airway-measurements-and-postoperative-respiratory-events-in-young-children-100623288","NCT07394686","Ultrasonographic Subglottic Airway Measurements and Postoperative Respiratory Events in Young Children","Association Between Ultrasonographic Subglottic Airway Measurements and Postoperative Respiratory Adverse Events in Children Under Three Years of Age","Inclusion Criteria:\n\n* Children aged 0 to 35 months\n* Scheduled for elective surgery under general anesthesia\n* Planned airway management with a laryngeal mask airway\n* Ability to perform intraoperative ultrasonographic subglottic airway measurements\n* Written informed consent obtained from a parent or legal guardian\n\nExclusion Criteria:\n\n* Known congenital or acquired airway anomalies\n* Craniofacial anomalies\n* Emergency surgical procedures\n* Planned tracheal intubation instead of laryngeal mask airway\n* Inability to obtain adequate ultrasonographic subglottic airway measurements","3 Years",{"count":84,"type":21},350,"This study aims to better understand postoperative respiratory adverse events that may occur in some children under three years of age undergoing airway management during surgery. As part of the study, ultrasonographic measurements of a portion of the upper airway will be performed during surgery using a non-invasive ultrasound device. These measurements will be evaluated in relation to perioperative respiratory outcomes. The results of this study may contribute to improved understanding of airway-related factors associated with postoperative respiratory safety in young children.",[87,88],"Perioperative Respiratory Adverse Events","Postoperative Respiratory Complications",[88,90,91,92],"Pediatric airway","Pediatric airway evaluation","Subglottic airway measurements","2026-02-05",{"date":95,"type":38},"2026-02-06",{"date":97,"type":21},"2026-02-01",{"date":99,"type":21},"2027-02-01",{"name":44,"class":45},{"id":102,"slug":103,"hasResults":11,"nctId":104,"briefTitle":105,"officialTitle":106,"acronym":4,"eligibilityCriteria":107,"healthyVolunteers":11,"sex":16,"minAge":54,"maxAge":4,"enrollmentInfo":108,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":110,"conditions":111,"keywords":116,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":93,"lastUpdatePostDateStruct":122,"startDateStruct":124,"completionDateStruct":126,"leadSponsor":128,"locationsCount":46},"100624125","ultrasound-evaluation-of-respiratory-muscles-during-mechanical-ventilation-weaning-in-icu-patients-100624125","NCT07405567","Ultrasound Evaluation of Respiratory Muscles During Mechanical Ventilation Weaning in ICU Patients","Ultrasonographic Evaluation of Diaphragm and Accessory Respiratory Muscles During Weaning in ICU Patients With Pneumonia","Inclusion Criteria:\n\n* Age ≥ 18 years\n* Admission to the intensive care unit with a diagnosis of pneumonia\n* Receiving invasive mechanical ventilation via endotracheal intubation\n* Expected to undergo a weaning process from mechanical ventilation\n* Written informed consent obtained from the patient or legally authorized representative\n\nExclusion Criteria:\n\n* Known neuromuscular disease affecting respiratory muscles\n* High cervical spinal cord injury\n* History of major neck, thoracic, or diaphragmatic surgery\n* Acute thoracic trauma or pneumothorax\n* Central nervous system pathology affecting respiratory drive\n* Continuous neuromuscular blocking agent use\n* Pregnancy",{"count":109,"type":21},150,"Patients with pneumonia who require invasive mechanical ventilation in the intensive care unit (ICU) often experience difficulties during the process of being separated from the breathing machine (weaning). Failure of weaning is associated with longer ventilation duration, prolonged ICU stay, and increased risk of complications and death. Therefore, simple and reliable bedside tools are needed to better understand respiratory muscle function and to help predict weaning outcomes.\n\nThis prospective, observational, single-center study aims to evaluate respiratory muscle function using bedside ultrasound in adult ICU patients with pneumonia receiving invasive mechanical ventilation. The diaphragm, parasternal intercostal muscles, and anterior scalene muscles will be assessed using ultrasound during the weaning process. Measurements will be performed serially, starting from the first day when patients demonstrate meaningful spontaneous breathing effort and continuing until successful extubation, tracheostomy, or ICU mortality.\n\nUltrasound measurements of muscle thickness and thickening fraction will be analyzed in relation to weaning outcomes. In addition, ventilator parameters and commonly used weaning indices will be recorded at the time of each ultrasound assessment. The findings of this study are expected to improve understanding of respiratory muscle involvement during weaning and may contribute to earlier identification of patients at risk of weaning failure.",[112,113,114,115],"Pneumonia","Invasive Mechanical Ventilation","Weaning From Mechanical Ventilation in Care Unit","Respiratory Muscle Dysfunction",[117,118,119,120,121],"Mechanical Ventilation Weaning","Respiratory Muscle Ultrasound","Diaphragm Ultrasound","Parasternal Intercostal Muscle","Anterior Scalene Muscle",{"date":123,"type":38},"2026-02-12",{"date":125,"type":21},"2026-02-15",{"date":127,"type":21},"2027-02-15",{"name":44,"class":45},{"id":130,"slug":131,"hasResults":11,"nctId":132,"briefTitle":133,"officialTitle":134,"acronym":4,"eligibilityCriteria":135,"healthyVolunteers":136,"sex":16,"minAge":54,"maxAge":4,"enrollmentInfo":137,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":138,"conditions":139,"keywords":148,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":155,"lastUpdatePostDateStruct":156,"startDateStruct":158,"completionDateStruct":159,"leadSponsor":160,"locationsCount":46},"100623641","submental-tissue-oxygenation-and-arterial-lactate-in-major-surgery-100623641","NCT07399275","Submental Tissue Oxygenation and Arterial Lactate in Major Surgery","Relationship Between Submental Tissue Oxygenation, Microvascular Reactivity, and Arterial Lactate During Major Surgical Procedures","Inclusion Criteria:\n\n* Adults aged 18 years and older\n* Scheduled for major surgical procedures under general anesthesia\n* Major surgery defined as procedures associated with a risk of significant blood loss and\u002For impaired tissue perfusion, requiring invasive arterial blood pressure monitoring and hourly arterial blood gas analysis\n* Planned intraoperative arterial catheter placement as part of routine clinical care\n* Ability to provide written informed consent\n\nExclusion Criteria:\n\n* Age younger than 18 years\n* Refusal or inability to provide informed consent\n* Absence of invasive arterial blood pressure monitoring\n* Known pregnancy\n* Severe peripheral vascular disease affecting upper extremities\n* Anatomical abnormalities or skin conditions preventing placement of NIRS sensors on the submental or thenar regions\n* Emergency surgery requiring immediate intervention\n* Preoperative severe metabolic acidosis (arterial pH \\\u003C 7.20)",true,{"count":109,"type":21},"During major surgical procedures performed under general anesthesia, changes in blood flow and oxygen delivery to tissues may occur due to blood loss, hemodynamic fluctuations, and anesthesia-related physiological effects. These changes can lead to impaired tissue perfusion, which is commonly reflected by increased arterial lactate levels. However, lactate measurements are intermittent and may not detect early perfusion abnormalities.\n\nThis prospective observational study aims to investigate the relationship between submental tissue oxygenation measured by near-infrared spectroscopy (NIRS), microvascular reactivity assessed by the vascular occlusion test, and arterial lactate levels during major surgery. Adult patients undergoing major abdominal, neurosurgical, or orthopedic procedures will be monitored intraoperatively using non-invasive NIRS techniques, while arterial blood gas analyses will be performed as part of routine clinical care.\n\nThe study does not involve any changes to standard anesthesia or surgical management. All treatments and clinical decisions will be made by the responsible care team according to routine practice. By evaluating non-invasive indicators of tissue oxygenation and microvascular function, this study aims to improve the understanding of early intraoperative tissue perfusion changes and their association with metabolic markers.",[140,141,142,143,144,145,146,147],"Microcirculatory Dysfunction","Tissue Hypoperfusion","Microcirculatory Status","Microvascular Circulation","Near Infrared Spectroscopy","Vascular Occlusion Test","Lactate Blood Increase","Major Surgery",[149,150,151,152,153,154],"tissue hypoperfusion","microvascular circulation","Near infrared spectroscopy","vascular occlusion","lactate blood increase","Major surgery","2026-02-03",{"date":157,"type":38},"2026-02-10",{"date":125,"type":21},{"date":127,"type":21},{"name":44,"class":45},""]