[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Camilo Jose Cela University\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":123},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,4,0,[8,42,67,94],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":14,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":28,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":31,"lastUpdatePostDateStruct":32,"startDateStruct":35,"completionDateStruct":37,"leadSponsor":39,"locationsCount":4},"100625623","effectiveness-of-manual-lymphatic-drainage-in-the-physiotherapeutic-treatment-of-migraine-100625623",false,"NCT07425041","Effectiveness of Manual Lymphatic Drainage in the Physiotherapeutic Treatment of Migraine","EDLMMG","Inclusion Criteria:\n\n* Male or female, aged 20 to 55 years.\n* Clinical diagnosis of migraine and experiencing migraine episodes with a minimum frequency of 4 times per month.\n\nExclusion Criteria:\n\n* Participants with arterial hypertension who are taking antihypertensive medication.\n* Participants currently taking prophylactic medication for migraine.\n* Participants with fibromyalgia.","ALL","20 Years","55 Years",{"count":20,"type":21},20,"ESTIMATED","INTERVENTIONAL",[24],"NA","Migraine is a highly prevalent neurological disorder associated with recurrent headache, disability, and reduced quality of life. In addition to pain, migraine is frequently accompanied by autonomic dysfunction, psychological comorbidities, and sleep disturbances. Manual lymphatic drainage (MLD) is a physiotherapy technique that may influence pain perception and autonomic regulation by promoting lymphatic and venous return and facilitating parasympathetic activity.\n\nThe aim of this pilot clinical study is to evaluate the effectiveness of manual lymphatic drainage in patients with migraine. Participants will be allocated to an experimental group receiving manual lymphatic drainage or to a control group. Outcomes related to pain intensity, pressure pain thresholds, migraine-related disability, quality of life, psychological variables, sleep quality, and vital signs will be assessed at baseline, after the intervention, and during follow-up periods.\n\nThis study seeks to provide preliminary evidence on the feasibility and potential clinical effects of manual lymphatic drainage as a non-pharmacological physiotherapy approach for migraine management.",[27],"Migraine",[29,27],"Manual Lymphatic Drainage","NOT_YET_RECRUITING","2026-02-20",{"date":33,"type":34},"2026-02-23","ACTUAL",{"date":36,"type":21},"2026-03-20",{"date":38,"type":21},"2026-08-01",{"name":40,"class":41},"Camilo Jose Cela University","OTHER",{"id":43,"slug":44,"hasResults":11,"nctId":45,"briefTitle":46,"officialTitle":46,"acronym":47,"eligibilityCriteria":48,"healthyVolunteers":11,"sex":49,"minAge":50,"maxAge":51,"enrollmentInfo":52,"targetDuration":4,"studyType":22,"phases":53,"briefSummary":54,"conditions":55,"keywords":57,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":59,"lastUpdatePostDateStruct":60,"startDateStruct":62,"completionDateStruct":64,"leadSponsor":66,"locationsCount":4},"100622042","evaluation-of-the-effectiveness-of-manual-lymphatic-drainage-in-young-women-with-primary-dysmenorrhea-100622042","NCT07378475","Evaluation of the Effectiveness of Manual Lymphatic Drainage in Young Women With Primary Dysmenorrhea","EDLMDP","Inclusion Criteria:\n\n* Female participants aged 18-25 years\n* Confirmed diagnosis of primary dysmenorrhea\n* Regular menstrual cycles\n* Ability to provide informed consent\n\nExclusion Criteria:\n\n* Secondary dysmenorrhea\n* Use of hormonal contraceptives\n* Presence of pelvic pathology (endometriosis, polycystic ovary syndrome, fibroids)\n* Irritable bowel syndrome\n* Use of analgesics or anti-inflammatory drugs within 12 hours prior to intervention\n* Any therapy for dysmenorrhea in the previous month\n* Pregnancy or suspected pregnancy\n* Irregular menstrual cycles","FEMALE","18 Years","25 Years",{"count":20,"type":21},[24],"This pilot clinical trial aims to evaluate the effectiveness of manual lymphatic drainage (MLD) in reducing symptoms associated with primary dysmenorrhea in young women. Primary dysmenorrhea is a common gynecological condition characterized by intense pelvic pain during menstruation, often accompanied by fatigue, headache, and sleep disturbances. Despite its high prevalence, it is frequently underestimated, negatively impacting quality of life and daily activities.\n\nThe intervention consists of three monthly sessions of MLD performed during the late luteal phase, prior to menstruation. Outcome measures include pain intensity, abdominal circumference, pressure pain threshold, sleep quality, and health-related quality of life.",[56],"Dysmenorrhea Primary",[29,58],"physiotherapy","2026-02-03",{"date":61,"type":34},"2026-02-05",{"date":63,"type":21},"2026-01-30",{"date":65,"type":21},"2026-07-01",{"name":40,"class":41},{"id":68,"slug":69,"hasResults":11,"nctId":70,"briefTitle":71,"officialTitle":71,"acronym":72,"eligibilityCriteria":73,"healthyVolunteers":74,"sex":49,"minAge":75,"maxAge":17,"enrollmentInfo":76,"targetDuration":4,"studyType":22,"phases":78,"briefSummary":79,"conditions":80,"keywords":82,"overallStatus":84,"whyStopped":4,"lastUpdateSubmitDate":85,"lastUpdatePostDateStruct":86,"startDateStruct":88,"completionDateStruct":90,"leadSponsor":92,"locationsCount":93},"100614010","effect-of-manual-lymphatic-drainage-on-muscle-fatigue-in-female-11-a-side-football-players-100614010","NCT07274033","Effect of Manual Lymphatic Drainage on Muscle Fatigue in Female 11-a-side Football Players","EDLMF11","Inclusion Criteria:\n\n* Female athletes actively participating in 11-a-side football, either federated or official team members.\n* Age ≥ 16 years to 20 years old.\n* Regular training (≥ 3 sessions per week) or active competition\n* No food intake within 3 hours prior to evaluation (to standardize the influence of digestion on performance).\n* No acute lower limb injury in the past 3 months.\n* Availability to attend all three study visits.\n* Signed informed consent; for participants under 18, parental consent is also required.\n\nExclusion Criteria:\n\n* History of deep vein thrombosis\n* Decompensated heart failure\n* Active lower limb infection\n* Pregnancy\n* Recent lower limb surgery (\\\u003C 3 months), or any medical contraindication to receiving manual lymphatic drainage (MLD).\n* Failure to comply with the fasting requirement prior to performance testing.",true,"16 Years",{"count":77,"type":21},11,[24],"This clinical trial investigates the effectiveness of manual lymphatic drainage (MLD) in accelerating recovery following induced fatigue in female football players. The study integrates objective performance measurements using linear encoders with anthropometric assessments and psychophysiological evaluations. It aims to quantify the impact of MLD on neuromuscular recovery, muscle edema, and perceived fatigue, considering sex-specific physiological factors and the influence of sleep and psychological stress. The findings will contribute to developing non-invasive, individualized recovery strategies to enhance performance and reduce injury risk in women's football.",[81],"Women",[29,83,81],"Football","RECRUITING","2025-12-09",{"date":87,"type":34},"2025-12-10",{"date":89,"type":34},"2025-11-17",{"date":91,"type":21},"2026-07-30",{"name":40,"class":41},1,{"id":95,"slug":96,"hasResults":11,"nctId":97,"briefTitle":98,"officialTitle":99,"acronym":4,"eligibilityCriteria":100,"healthyVolunteers":11,"sex":16,"minAge":50,"maxAge":4,"enrollmentInfo":101,"targetDuration":4,"studyType":22,"phases":103,"briefSummary":104,"conditions":105,"keywords":107,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":115,"lastUpdatePostDateStruct":116,"startDateStruct":118,"completionDateStruct":120,"leadSponsor":122,"locationsCount":4},"100588209","effectiveness-of-percutaneous-electrolysis-and-dry-needling-vs-standard-therapy-for-whiplash-syndrome-100588209","NCT06938425","Effectiveness of Percutaneous Electrolysis and Dry Needling vs. Standard Therapy for Whiplash Syndrome","Effectiveness of Intratissue Percutaneous Electrolysis and Deep Dry Needling Versus a Standard Physical Therapy Protocol in the Treatment of Whiplash Syndrome in the Short and Medium Term","Inclusion Criteria:\n\n* Adults with whiplash syndrome following a traffic accident.\n* Patients must reside or stay in the Autonomous Community of Melilla during the intervention phase.\n* Subjects will have the presence of neck pain after suffering a traffic accident and the presence of at least one active trigger point in the sternocleidomastoid and\u002For levator scapulae muscles.\n* All subjects who suffer a traffic accident and who have a score of 5 or higher on the numerical scale (EN) of pain assessment.\n\nExclusion Criteria:\n\n* Patients undergoing anticoagulant treatment.\n* Patients who have suffered previous cervical trauma or who have undergone surgery in the last year.\n* Subjects who present some type of alteration (skin or infection, sensitivity or pain perception).\n* Subjects with central or peripheral nervous system involvement.\n* Patients who have problems with the material: allergy to metal, belonephobia (fear of needles).\n* Pregnant women.",{"count":102,"type":21},36,[24],"The main objective of this research is to evaluate the effectiveness of two interventions (PIE vs DDN) in adult patients who have suffered a LCS after a traffic accident and comparing it with a standard physiotherapy program. As a secondary objective, the investigators will analyze the reduction of intrafibrillar blood flow and muscle elasticity perceived by the patient in the long term and the reduction of pain and disability appreciated by the patient.\n\nIt is hypothesized as an alternative hypothesis that percutaneous electrolysis and\u002For deep dry needling intervention in combination with standard physiotherapy will give better clinical outcomes in patients with active trigger point LCS following a road traffic accident compared to the current standard physiotherapy intervention.\n\nThe researchers will compare both invasive physical therapy techniques with standard treatment to see if these techniques are more effective in treating whiplash syndrome.",[106],"Whiplash Injuries",[108,109,110,111,112,113,114],"Percutaneous electrolysis","Dry needling","Whiplash","Myofascial pain syndrome","Myofascial trigger point","Intrafibrillar blood flow","elasticity","2025-11-25",{"date":117,"type":34},"2025-11-26",{"date":119,"type":21},"2025-11-30",{"date":121,"type":21},"2026-09-01",{"name":40,"class":41},""]