[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"CardioMech AS\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":40},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":4,"overallStatus":27,"whyStopped":4,"lastUpdateSubmitDate":28,"lastUpdatePostDateStruct":29,"startDateStruct":32,"completionDateStruct":34,"leadSponsor":36,"locationsCount":39},"100425499","efs-of-the-cardiomech-mvrs-100425499",false,"NCT04820764","EFS of the CardioMech MVRS","Early Feasibility Study of the CardioMech Mitral Valve Repair System (MVRS)","Inclusion Criteria:\n\n* Eighteen (18) years of age or greater\n* Moderate to severe (≥3+) or severe (≥4+) mitral valve regurgitation (per American Society of Echocardiography (ASE) guidelines) due to mitral valve prolapse or flail\n* Intermediate or high surgical risk for mitral valve repair\n\nExclusion Criteria:\n\n* History of rheumatic heart disease\n* History of prior endocarditis\n* History of prior repair or replacement of the mitral valve, or annuloplasty\n* Severely calcified mitral leaflet or has evidence of calcification in the grasping area of the leaflets that would prevent leaflet anchor positioning and deployment\n* Complex mechanism of MR (leaflet perforation, severe leaflet calcifications, commissural extension, commissural prolapse, multiple flail or prolapsing segments, cleft) present on required imaging","ALL","18 Years",{"count":19,"type":20},25,"ESTIMATED","INTERVENTIONAL",[23],"NA","Safety and performance evaluation of the CardioMech Mitral Valve Repair System (MVRS) in patients with degenerative mitral valve regurgitation.",[26],"Mitral Regurgitation","RECRUITING","2026-02-06",{"date":30,"type":31},"2026-02-10","ACTUAL",{"date":33,"type":31},"2021-07-27",{"date":35,"type":20},"2031-09",{"name":37,"class":38},"CardioMech AS","INDUSTRY",12,""]