[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Casa Colina Hospital and Centers for Healthcare\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":118},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,4,0,[8,39,68,95],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":23,"conditions":24,"keywords":4,"overallStatus":27,"whyStopped":4,"lastUpdateSubmitDate":28,"lastUpdatePostDateStruct":29,"startDateStruct":32,"completionDateStruct":34,"leadSponsor":36,"locationsCount":4},"100634138","implementing-transcranial-direct-current-stimulation-in-a-rehabilitation-setting-100634138",false,"NCT07535788","Implementing Transcranial Direct Current Stimulation in a Rehabilitation Setting","Implementing Transcranial Direct Current Stimulation (tDCS) in an Acute Rehabilitation Setting","tDCS implement","Inclusion Criteria:\n\n* ischemic or hemorrhagic stroke\n* aphasia\n\nExclusion Criteria:\n\n* not a patient at either inpatient and outpatient settings of Casa Colina Hospital and Centers for Healthcare","ALL","18 Years",{"count":20,"type":21},30,"ESTIMATED","OBSERVATIONAL","This study looks at whether transcranial Direct Current Stimulation (tDCS) can be effectively implemented in inpatient and outpatient rehabilitation settings during routine speech therapy for people who recently had a stroke and now have aphasia (difficulty speaking or understanding language)",[25,26],"Aphasia","Stroke","NOT_YET_RECRUITING","2026-04-15",{"date":30,"type":31},"2026-04-17","ACTUAL",{"date":33,"type":21},"2026-05-04",{"date":35,"type":21},"2027-05-30",{"name":37,"class":38},"Casa Colina Hospital and Centers for Healthcare","OTHER",{"id":40,"slug":41,"hasResults":11,"nctId":42,"briefTitle":43,"officialTitle":44,"acronym":45,"eligibilityCriteria":46,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":47,"enrollmentInfo":48,"targetDuration":4,"studyType":50,"phases":51,"briefSummary":53,"conditions":54,"keywords":55,"overallStatus":58,"whyStopped":4,"lastUpdateSubmitDate":59,"lastUpdatePostDateStruct":60,"startDateStruct":62,"completionDateStruct":64,"leadSponsor":66,"locationsCount":67},"100533490","eeg-changes-and-dna-markers-related-to-tavns-in-stroke-patients-a-preliminary-study-100533490","NCT06226493","EEG Changes and DNA Markers Related to taVNS in Stroke Patients: a Preliminary Study","EEG Changes and DNA Markers Related to Transcutaneous Auricular Vagus Nerve Stimulation (taVNS) in Acute Stroke Patients: a Preliminary Study","StrokeVNS","Inclusion Criteria:\n\n* First-time Cerebrovascular Accident (Ischemic or Hemorrhagic)\n* Within a month post-injury\n* Presence of motor impairments (FMA-U≤62)\n\nExclusion Criteria:\n\n* Advanced cardiac, pulmonary, liver, or kidney disease\n* Bradycardia (Resting HR \\\u003C 60)\n* Presence of Apraxia, Aphasia or confusion\n* Other musculoskeletal or neurologic diseases that could interfere with the outcome measures\n* Previous surgical intervention on the vagus nerve\n* Participation in other clinical trials\n* Alcohol or drug abuse","80 Years",{"count":49,"type":21},44,"INTERVENTIONAL",[52],"NA","In the United States, more than 795,000 people have a stroke every year. Motor impairment after a stroke is common and can be debilitating. To date, there remain few treatments available to help improve motor recovery after a stroke, making this an important area of research. Novel use of neuromodulation such as Invasive Vagus Nerve Stimulation (VNS) has been shown to improve motor recovery in stroke patients. Vagus nerve stimulation (VNS), in which the nerve is stimulated with electrical pulses, has demonstrated success for a variety of conditions, including inflammation, depression, cognitive dysfunction, chronic fatigue, headaches\u002Fmigraines, pain, insomnia, and cardiovascular issues. Very recently, non-invasive options have been developed and might be a promising alternative. The research in this area is still very limited and much more research is needed to investigate non-invasive\u002Ftrancutaneous auricular vagus nerve stimulation (taVNS) related biomechanisms and to further support its efficacy in acute patients. The purpose of this study is to build upon the current research to investigate changes in electrical brain activity (using electrophysiology) and genetic markers related to improvements in both motor and cognitive recovery following the use of taVNS vs. sham in acute stroke patients.",[26],[56,57],"vagus nerve stimulation","electrophysiology","RECRUITING","2026-03-26",{"date":61,"type":31},"2026-03-31",{"date":63,"type":31},"2024-01-29",{"date":65,"type":21},"2027-01-30",{"name":37,"class":38},1,{"id":69,"slug":70,"hasResults":11,"nctId":71,"briefTitle":72,"officialTitle":73,"acronym":4,"eligibilityCriteria":74,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":47,"enrollmentInfo":75,"targetDuration":4,"studyType":50,"phases":77,"briefSummary":78,"conditions":79,"keywords":82,"overallStatus":27,"whyStopped":4,"lastUpdateSubmitDate":87,"lastUpdatePostDateStruct":88,"startDateStruct":90,"completionDateStruct":92,"leadSponsor":94,"locationsCount":67},"100630817","comparison-of-gait-metrics-in-patients-with-stroke-traumatic-brain-injury-and-multiple-sclerosis-100630817","NCT07492602","Comparison of Gait Metrics in Patients With Stroke, Traumatic Brain Injury, and Multiple Sclerosis","Comparison of Gait Metrics in Patients With Stroke, Traumatic Brain Injury, and Multiple Sclerosis Before and After Functional Electrical Stimulation","Inclusion Criteria:\n\n* Adults aged 18-80 years.\n* Diagnosis of stroke, traumatic brain injury, or multiple sclerosis confirmed by medical records.\n* Presence of foot drop or impaired ankle dorsiflexion during gait.\n* Ability to ambulate at least 10 meters with or without assistive devices.\n* Cognitive ability to follow simple instructions and provide informed consent.\n\nExclusion Criteria:\n\n* Severe lower limb contractures or orthopedic conditions that limit gait.\n* Implanted electrical devices (e.g., pacemaker) contraindicating FES use.\n* Uncontrolled medical conditions (e.g., severe cardiac disease).\n* Pregnancy.\n* Skin integrity issues preventing electrode placement.\n* Participation in other interventional gait studies within the past 3 months.",{"count":76,"type":21},90,[52],"People with neurological conditions often have difficulty walking, including problems such as foot drop. Functional electrical stimulation (FES) is a treatment that uses electrical signals to activate muscles and support walking. The L300 device is designed to help lift the foot during each step.\n\nThis study will evaluate how using the L300 affects walking performance. Researchers will measure walking speed, step length, and walking symmetry using objective gait assessment tools. The study will also explore whether people with different neurological conditions respond differently to FES.\n\nThe goal of this research is to improve understanding of how FES influences walking and to support more personalized rehabilitation approaches.",[26,80,81],"Traumatic Brain Injury","Multiple Sclerosis",[83,84,26,85,86],"FES","Gait","TBI","MS","2026-03-24",{"date":89,"type":31},"2026-03-27",{"date":91,"type":21},"2026-04-01",{"date":93,"type":21},"2027-02-01",{"name":37,"class":38},{"id":96,"slug":97,"hasResults":11,"nctId":98,"briefTitle":99,"officialTitle":100,"acronym":4,"eligibilityCriteria":101,"healthyVolunteers":102,"sex":17,"minAge":18,"maxAge":103,"enrollmentInfo":104,"targetDuration":4,"studyType":50,"phases":106,"briefSummary":107,"conditions":108,"keywords":4,"overallStatus":58,"whyStopped":4,"lastUpdateSubmitDate":110,"lastUpdatePostDateStruct":111,"startDateStruct":113,"completionDateStruct":115,"leadSponsor":117,"locationsCount":67},"100557227","blood-flow-restriction-training-on-upper-extremity-grip-strength-100557227","NCT06535373","Blood Flow Restriction Training on Upper Extremity Grip Strength","Restrict and Strengthen: Unraveling the Impact of Blood Flow Restriction Training on Upper Extremity Grip Strength","Inclusion Criteria:\n\n* Participants must be between 18 and 35 years old at the time of enrollment.\n\nParticipants should be in good general health with no known cardiovascular, musculoskeletal, or neurological disorders that could interfere with exercise participation.\n\nParticipants must provide informed consent before enrollment in the study, indicating their willingness to participate voluntarily.\n\nExclusion Criteria:\n\n* Participants with a history of cardiovascular disease (e.g., heart disease, hypertension), musculoskeletal injuries (e.g., fractures, dislocations), or neurological disorders (e.g., neuropathy) that could affect exercise performance will be excluded.\n\nParticipants taking medications or supplements that may impact muscle strength, metabolism, or blood flow will be excluded from the study.\n\nPregnant individuals will be excluded due to potential risks associated with exercise and blood flow restriction during pregnancy.\n\nIndividuals with recent upper extremity injuries, such as strains, sprains, or fractures, will be excluded until fully recovered.\n\nBlood Pressure: Participants with uncontrolled high blood pressure or other medical conditions affecting vascular health may be excluded due to potential risks associated with blood flow restriction.",true,"35 Years",{"count":105,"type":21},40,[52],"The primary objective of this prospective study is to investigate the effects of Blood Flow Restriction (BFR) training compared to traditional low-weight resistance training on grip strength in young adults.\n\nDespite the growing interest in BFR training and its potential benefits, there is limited research specifically investigating its impact on grip strength. Understanding the effects of BFR training on grip strength could have significant implications for individuals seeking to optimize their grip performance, rehabilitation settings, and sports performance enhancement. Additionally, examining the safety and efficacy of BFR training for this specific outcome will contribute valuable insights to the scientific community.",[109],"Healthy Volunteers","2024-10-09",{"date":112,"type":31},"2024-10-15",{"date":114,"type":31},"2024-08-19",{"date":116,"type":21},"2025-12",{"name":37,"class":38},""]