[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Center for Innovative Public Health Research\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":127},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,4,0,[8,57,81,105],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":17,"sex":18,"minAge":19,"maxAge":20,"enrollmentInfo":21,"targetDuration":4,"studyType":24,"phases":25,"briefSummary":27,"conditions":28,"keywords":33,"overallStatus":44,"whyStopped":4,"lastUpdateSubmitDate":45,"lastUpdatePostDateStruct":46,"startDateStruct":49,"completionDateStruct":51,"leadSponsor":53,"locationsCount":56},"100645303","transcendenthealth-a-text-messaging-pregnancy-prevention-program-for-transgender-boys-100645303",false,"NCT07681908","#TranscendentHealth: A Text Messaging Pregnancy Prevention Program for Transgender Boys","#TranscendentHealth - Adapting an LGB+ Inclusive Teen Pregnancy Prevention Program for Transgender Boys","THPP","Inclusion Criteria:\n\n* Assigned female sex at birth\n* Does not have an exclusively cisgender gender identity (e.g., identifies as transgender boy, nonbinary, gender fluid, or unsure of gender identity)\n* Age 14 to 18 years and has not yet graduated from high school\n* Exclusive owner of a cell phone with an unlimited text messaging plan\n* Has access to the Internet to complete online surveys\n* Plans to keep the same cell phone number for at least the next 6 months\n* Able to provide informed assent (ages 14-17) or consent (age 18), including the capacity to do so\n* Has not participated in a prior #TranscendentHealth study activity and does not know anyone currently enrolled in the study\n\nExclusion Criteria:\n\n* Has graduated from high school\n* Has participated in a prior #TranscendentHealth study activity (focus groups, Content Advisory Teams, or beta test)\n* Knows another person currently enrolled in the study",true,"FEMALE","14 Years","18 Years",{"count":22,"type":23},467,"ESTIMATED","INTERVENTIONAL",[26],"NA","Transgender and gender-diverse young people who were assigned female at birth (AFAB), including transgender boys, nonbinary youth, and others, face real sexual health disparities. Existing pregnancy and HIV prevention programs are designed for cisgender girls and do not meet the needs of AFAB trans youth, leaving this group without programs that speak to their lives.\n\n#TranscendentHealth is a text messaging sexual health program developed specifically for AFAB transgender and gender-diverse youth ages 14 to 18. It builds on Girl2Girl, a program shown to improve sexual health behaviors in LGB+ cisgender girls, and updates the content to reflect the identities, relationships, and health needs of AFAB trans youth.\n\nThe study has two parts. In the first part, AFAB trans youth help shape the program through focus groups, Content Advisory Teams (youth review panels that give feedback on program messages), and a small pilot test. In the second part, a national randomized controlled trial enrolls 467 AFAB transgender youth ages 14 to 18 across the United States. Participants are randomly assigned to receive either #TranscendentHealth or a general sexual health text messaging program. Both programs are delivered entirely by text message over 5 months, with no in-person visits required. Youth complete short online surveys at the start of the program, at program end (5 months), and at 3 and 6 months after the program ends.\n\nThe study's main goals are to determine whether #TranscendentHealth improves rates of condom-protected sex, use of other birth control methods (such as the pill, shot, or IUD), and HIV\u002FSTI testing. Secondary goals include reducing unintended pregnancy, increasing PrEP uptake among eligible participants, and improving intentions to use sexual health services.",[29,30,31,32],"Pregnancy (Unwanted)","Sexually Transmitted Disease (STD)","HIV Infection","Sexual Behavior",[34,35,36,37,38,39,40,41,42,43],"transgender youth","Nonbinary youth","Assigned female at birth (AFAB)","Pregnancy prevention","Text messaging","mHealth","Sexual health","Gender minority youth","HIV prevention","Contraception","NOT_YET_RECRUITING","2026-07-01",{"date":47,"type":48},"2026-07-02","ACTUAL",{"date":50,"type":23},"2026-06-30",{"date":52,"type":23},"2028-06-30",{"name":54,"class":55},"Center for Innovative Public Health Research","OTHER",1,{"id":58,"slug":59,"hasResults":11,"nctId":60,"briefTitle":61,"officialTitle":62,"acronym":63,"eligibilityCriteria":64,"healthyVolunteers":17,"sex":65,"minAge":20,"maxAge":66,"enrollmentInfo":67,"targetDuration":4,"studyType":24,"phases":69,"briefSummary":70,"conditions":71,"keywords":4,"overallStatus":44,"whyStopped":4,"lastUpdateSubmitDate":73,"lastUpdatePostDateStruct":74,"startDateStruct":76,"completionDateStruct":78,"leadSponsor":80,"locationsCount":56},"100622372","in-this-together-r01-100622372","NCT07382765","In This toGether R01","In This toGether: Testing a Population-based Text Messaging-based HIV Prevention Program for Young Adults Across Uganda","ITG","Inclusion Criteria:\n\n* Live in Uganda\n* Age 18 to 22\n* Have exclusive ownership of a cell phone\n* Have used text messaging for at least 6 months\n* Able to read English, Luganda, Runyakitara, or Luo\n\nExclusion Criteria:\n\n* Not participated in preliminary R34 study","ALL","22 Years",{"count":68,"type":23},750,[26],"The goal of this study is to assess the effectiveness of the text-based ITG intervention to promote behaviors associated with HIV prevention amongst 18-22 year-olds in Uganda.\n\nThe main questions the study aims to answer are:\n\n1. In a twelve-month period, does the intervention increase HIV testing and use of condoms?\n\n   a. How do the different interactive elements effect this?\n2. How is effectiveness different for populations based on education, sex, and location (urban\u002Frural)? Researchers will compare the control group, with no intervention, and the three combinations of the three intervention components: quiz questions, milestone badges, and access to on-demand advice.\n\nParticipants will receive the intervention via text messages and partake in the interactive elements listed above.",[72],"HIV","2026-01-27",{"date":75,"type":48},"2026-02-03",{"date":77,"type":23},"2026-03-01",{"date":79,"type":23},"2028-06",{"name":54,"class":55},{"id":82,"slug":83,"hasResults":11,"nctId":84,"briefTitle":85,"officialTitle":86,"acronym":4,"eligibilityCriteria":87,"healthyVolunteers":17,"sex":88,"minAge":19,"maxAge":20,"enrollmentInfo":89,"targetDuration":4,"studyType":24,"phases":91,"briefSummary":92,"conditions":93,"keywords":95,"overallStatus":97,"whyStopped":4,"lastUpdateSubmitDate":98,"lastUpdatePostDateStruct":99,"startDateStruct":101,"completionDateStruct":103,"leadSponsor":104,"locationsCount":56},"100561130","testing-a-gender-inclusive-hiv-prevention-program-100561130","NCT06586151","Testing a Gender-inclusive HIV Prevention Program","Harnessing the Power of Technology to Develop a Population-based HIV Prevention Program for Trans Girls","Inclusion Criteria:\n\n1. assigned male sex at birth and currently have a non-cisgender identity (e.g., transgender girl, non-binary, gender fluid, unsure);\n2. aged 14-18 years and have not yet graduated high school;\n3. English-speaking;\n4. the sole user of a cell phone with an unlimited text messaging plan;\n5. have access to the Internet to complete online surveys;\n6. intend to have the same cell number for the next 6 months;\n7. provide informed assent;\n8. not have taken part in a previous #TranscendentHealth study activity or know someone who is in the study to increase the diversity of input from transgirls, and\n9. agree to enroll over the phone with study staff.\n\nExclusion Criteria:\n\n* None beyond not meeting inclusion criteria","MALE",{"count":90,"type":23},200,[26],"If, over time, data suggest the intervention impacts HIV preventive behavior at the population level, it will be unique in that it can be quickly and cost effectively scaled up to impact thousands of trans girls and nonbinary youth assigned male at birth.",[94],"HIV Prevention",[72,96,39],"Adolescence","RECRUITING","2025-12-01",{"date":100,"type":48},"2025-12-08",{"date":102,"type":48},"2024-09-01",{"date":50,"type":23},{"name":54,"class":55},{"id":106,"slug":107,"hasResults":11,"nctId":108,"briefTitle":109,"officialTitle":110,"acronym":111,"eligibilityCriteria":112,"healthyVolunteers":17,"sex":88,"minAge":113,"maxAge":66,"enrollmentInfo":114,"targetDuration":4,"studyType":24,"phases":116,"briefSummary":117,"conditions":118,"keywords":4,"overallStatus":97,"whyStopped":4,"lastUpdateSubmitDate":98,"lastUpdatePostDateStruct":120,"startDateStruct":121,"completionDateStruct":123,"leadSponsor":125,"locationsCount":126},"100533788","sexual-health-advocacy-for-guys---a-text-messaging-based-hiv-prevention-program-for-guys-who-are-into-guys-100533788","NCT06230367","Sexual Health Advocacy for Guys - a Text Messaging-based HIV Prevention Program for Guys Who Are Into Guys","Harnessing the Power of Text Messaging to Reduce HIV Incidence in Adolescent Males Across the United States","SHAG","Inclusion Criteria:\n\n1. have been assigned male sex at birth and currently have a cisgender identity;\n2. be aged 13-22 years old;\n3. have had anal sex in the past 12 months;\n4. be English-speaking;\n5. exclusively own a cell phone with an unlimited text messaging plan and intend to have the same cell phone number for the next 6 months;\n6. have Internet access to complete online surveys;\n7. provide informed assent for those under 18, and consent for those 18 years of age and older, including a capacity to consent and a positive self-safety assessment;\n8. Willing to take an OraQuick home test to confirm HIV negativity for youth who are 19-20 years of age or 18 years old and graduated high school. If they agree to do the test but do not upload a photo of their result, they will be eligible if they self-report a negative sero-status. Youth 18 years old who have not graduated high school, and 13-17 years of age will be asked to take a home test. If they determine that they cannot do so safely, they will be allowed to self-report their sero-status; and\n9. not currently enrolled in another HIV prevention program; or\n10. know anyone already enrolled in the RCT.\n\nExclusion Criteria:\n\n* Being HIV positive","13 Years",{"count":115,"type":23},5000,[26],"SHAG is a text messaging-based HIV prevention program designed for cisgender sexual minority boys and men 13-20 years of age across the United States. Investigators will test it against a control group that receives messages about healthy lifestyle.",[119],"HIV Infections",{"date":100,"type":48},{"date":122,"type":48},"2024-01-15",{"date":124,"type":23},"2026-07-31",{"name":54,"class":55},2,""]