[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Centre Hospitalier Metropole Savoie\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":236},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,8,0,[8,48,81,109,135,163,188,213],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":14,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":33,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":36,"lastUpdatePostDateStruct":37,"startDateStruct":40,"completionDateStruct":42,"leadSponsor":44,"locationsCount":47},"100589244","identification-of-pre-surgical-phenotypic-indicators-predictive-of-quality-of-life-trajectories-in-obese-patients-following-bariatric-surgery-100589244",false,"NCT06951893","Identification of Pre-surgical Phenotypic Indicators Predictive of Quality of Life Trajectories in Obese Patients Following Bariatric Surgery","PHENOBEQOL73","Inclusion Criteria:\n\n* patient \\> 18years old\n* Integrated into the GEROM73 surgical program and starting the intra-hospital program\n\nExclusion Criteria:\n\n* Patients in a state of psychiatric decompensation\n* Patients with cognitive disorders\n* Patients with difficulties understanding the French language, spoken or written\n* Pregnant, parturient, or breastfeeding women","ALL","18 Years",{"count":19,"type":20},165,"ESTIMATED","INTERVENTIONAL",[23],"NA","This study aims to identify pre-operative phenotypic determinants predictive of quality of life trajectories in post-bariatric surgery patients. In addition, this study will have as a secondary objective the highlighting of a potential link between post-surgery quality of life trajectories and those of anxiety\u002Fdepression scores, eating behaviors and body mass indices.\n\nThis study will be conducted during the usual care of patients undergoing the GEROM73 program, lasting a total of 30 months.\n\nThe GEROM73 program includes care for the six months preceding bariatric surgery and the 24 months following surgery. This program supports patients throughout their bariatric care..\n\nThroughout the GEROM73 program, patients will complete questionnaires on anxiety, depression, eating disorders, Impact of Weight on Quality Of Life.\n\nPatients' weight, body mass index and body schema will also be measured throughout the GEROM program.",[26,27,28,29,30,31,32],"Obesity, Morbid","Obesity and Overweight","Bariatric Surgery","Bariatric Surgery Patients","Bariatric Surgery Patient","Bariatric Surgery (Sleeve Gastrectomy )","Bypass, Gastric",[34,14],"GEROM73","RECRUITING","2026-06-09",{"date":38,"type":39},"2026-06-10","ACTUAL",{"date":41,"type":39},"2025-06-17",{"date":43,"type":20},"2030-09-09",{"name":45,"class":46},"Centre Hospitalier Metropole Savoie","OTHER",1,{"id":49,"slug":50,"hasResults":11,"nctId":51,"briefTitle":52,"officialTitle":53,"acronym":54,"eligibilityCriteria":55,"healthyVolunteers":56,"sex":16,"minAge":57,"maxAge":58,"enrollmentInfo":59,"targetDuration":4,"studyType":21,"phases":61,"briefSummary":62,"conditions":63,"keywords":67,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":36,"lastUpdatePostDateStruct":74,"startDateStruct":75,"completionDateStruct":77,"leadSponsor":79,"locationsCount":80},"100586887","exploratory-analysis-of-interpersonal-and-intrapersonal-psychological-processes-implied-in-risk-taking-and-suicidal-behaviors-in-adult-and-adolescent-at-risk-100586887","NCT06921226","Exploratory Analysis of Interpersonal and Intrapersonal Psychological Processes Implied in Risk-taking and Suicidal Behaviors, in Adult and Adolescent At-risk","Intra-personal and Interpersonal Psychological Processes Involved in Risk-taking and Suicidal Behaviors Among Vulnerable Adolescents and Adults","RISKY","Inclusion Criteria:\n\n* Age 12-65 years\n* Adolescent population considered as at risk in mental health : admitted to the peadiatric department (CHMS).\n\nor - Adult population : user of the Espoir73 association (an association for adults with a mental health problem) or users of SM@RT (CHS, a psycho-social rehabilitation center for adults with a mental illness).\n\nExclusion Criteria:\n\n\\- No suicidal ideation or behaviors (none \" Yes \" response at the 6 questions of the C-SSRS screen version).",true,"12 Years","65 Years",{"count":60,"type":20},1400,[23],"In a recent report, Santé Publique France (2023), reported that 4.2% of 18-85 year-olds had thought about suicide in the last 12 months, and 6.8% had attempted suicide in their lifetime and 0.5% in the last year. Even more recently, the DREES (Direction de la recherche, des études, de l'évaluation et des statistiques auprès des Ministères Sociaux) published a report on May 16, 2024, showing a sharp rise in hospitalization rates for self-inflicted acts among female patients aged between 10 and 24, with a peak around age 15. Two-thirds of these hospitalizations for self-inflicted injuries are related to deliberate drug intoxication. Depression, bipolar disorders and schizophrenia spectrum disorders (among other psychological disorders) are known risk factors for suicide, which is the leading cause of death in this clinical context. In addition to these formalized psychopathological elements, risk behaviors underpinned by psychological processes common to suicide attempts are suspected and need to be studied in depth.\n\nResearch into psychiatry and the psychopathology of suicide has identified a number of risk and protective factors. These psychological determinants - or processes - act alongside other key factors such as the environment and social ties. Life contexts can have an impact on health, and more specifically on the psychopathology of individuals, through disturbances of a biological, psychological and social nature. It is important to be able to describe what processes are at work and how they explain the development and maintenance of behaviours that put one's life and health at risk. This is part of a preventive approach to mental health. We suggest that the study of psychological processes such as suicidal ruminations, impulsivity and interpersonal needs (e.g. the interpersonal theory of suicide) is necessary to understand their involvement in risk-taking and suicidal behavior. To our knowledge, few studies of this type are underway in France, particularly with vulnerable clinical populations (adolescents\u002Fadults). The inclusion of a process-centered approach (Kinderman, 2015), in a transdiagnostic and preventive way, constitutes an innovative approach.",[64,65,66],"Suicidal Ideas","Suicidal Ideation","Risk-taking",[68,69,70,71,72,73],"Risk-taking behaviors","Impulsivity","Interpersonal needs","Suicidal ruminations","Suicidal behaviors","BART",{"date":38,"type":39},{"date":76,"type":39},"2025-06-26",{"date":78,"type":20},"2027-06-26",{"name":45,"class":46},3,{"id":82,"slug":83,"hasResults":11,"nctId":84,"briefTitle":85,"officialTitle":86,"acronym":87,"eligibilityCriteria":88,"healthyVolunteers":11,"sex":16,"minAge":89,"maxAge":4,"enrollmentInfo":90,"targetDuration":4,"studyType":21,"phases":92,"briefSummary":93,"conditions":94,"keywords":96,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":100,"lastUpdatePostDateStruct":101,"startDateStruct":103,"completionDateStruct":105,"leadSponsor":107,"locationsCount":108},"100635001","benefits-of-a-6-month-individualized-hybrid-real-life-adapted-physical-activity-program-on-the-quality-of-life-of-patients-treated-for-multiple-myeloma-100635001","NCT07547007","Benefits of a 6-month, Individualized, Hybrid, \"Real-life\" Adapted Physical Activity Program on the Quality of Life of Patients Treated for Multiple Myeloma","Benefits of a 6-month, Individualized, Hybrid, \"Real-life\" Adapted Physical Activity Program on the Quality of Life of Patients Treated for Multiple Myeloma: a Multicenter Randomized Controlled Trial","BAPAMM","Inclusion Criteria:\n\n* newly diagnosed or relapse multiple myeloma, \\> 60 yo, not eligible to transplant\n* 1st to 4th line of treatment initiated during the last 3 months\n* receiving a systemic treatment that involved visit to the hospital at least twice a month durig the first 3 months and at least once a month the next 3 months\n\nExclusion Criteria:\n\n* severe cardiac amyloidosis\n* absolute contraindication to physical activity\n* inability to comply with the protocol requirements\n* not french speaker\n* patient under guardianship or curatorship\n* pregnant or lactating women","61 Years",{"count":91,"type":20},86,[23],"The goal of this clinical trial is to evaluate the effect of a long-term, individualized, hybrid adapted physical activity program on the quality of life of patients with multiple myeloma. The main question it aims to answer are :\n\nDoes this logn term, individualized and hybrid adapted physical activity program improve quality of life in multiple myeloma patient ? What are the effects of this program on effort tolerance, pain, muscular mass, osteolytic lesions, tolerance to treatment, response to treatment? If there is a comparison group: Researchers will compare \\[arm information\\] to see if \\[insert effects\\].\n\nParticipants will be randomised in 2 groups.\n\n* control group: patients will receive only advices about physical activities benefit\n* interventional group: This group will be offered a program of adapted physical activities mixing sessions at home (remote) and sessions at the hospital (in person).",[95],"Multiple Myeloma (MM)",[97,98,99],"physical activity","multiple myeloma","control group","2026-04-16",{"date":102,"type":39},"2026-04-23",{"date":104,"type":39},"2026-01-22",{"date":106,"type":20},"2028-07-30",{"name":45,"class":46},2,{"id":110,"slug":111,"hasResults":11,"nctId":112,"briefTitle":113,"officialTitle":114,"acronym":115,"eligibilityCriteria":116,"healthyVolunteers":56,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":117,"targetDuration":4,"studyType":21,"phases":119,"briefSummary":120,"conditions":121,"keywords":124,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":127,"lastUpdatePostDateStruct":128,"startDateStruct":130,"completionDateStruct":132,"leadSponsor":134,"locationsCount":47},"100620206","effect-of-transcutaneous-electrical-stimulation-on-peripheral-blood-flow-100620206","NCT07354607","Effect of Transcutaneous Electrical Stimulation on Peripheral Blood Flow","Effect of Transcutaneous Electrical Stimulation on Peripheral Blood Flow - a Pilot Study","VASC-STIM","Inclusion Criteria:\n\n* Subject aged 18 years or older\n* Having freely given written consent, after being informed of the purpose of the study, its conduct and its risks.\n* Affiliated with a social security scheme\n\nExclusion Criteria:\n\n* Persons with pacemakers or any other implantable electrical devices,\n* Pregnant women\n* Suffering from dermatological conditions or muscle\u002Fskin lesions on the arms and forearms.\n* Participant unable to give free and informed consent.\n* Participant unable to comply with the specific procedures of the study.\n* Participant deprived of liberty or benefiting from legal protection measures.",{"count":118,"type":20},36,[23],"The goal of this clinical trial is to learn if transcutaneous electrical nerve stimulation can affect blood flow in healthy volunteers. The main question it aims to answer is:\n\nDetermine the stimulation parameters (frequency in the range 5- 100Hz and proximal or distal placement) inducing the most significant hyperaemic response in volunteers.\n\nParticipants will attend to one visit ( 1h30) , 6 protocol of stimulation will be tested on his arm . If his agree, an optionnal measure will be made during another visit. During this optionnal visit, two modalities of intensity adjustment will be tested in regard of the result of the first part of the study.",[122,123],"Volunteer","Adult",[125,126],"transcutaneous electrical nerve stimulation","blood flow","2026-03-09",{"date":129,"type":39},"2026-03-10",{"date":131,"type":39},"2026-02-04",{"date":133,"type":20},"2026-08-01",{"name":45,"class":46},{"id":136,"slug":137,"hasResults":11,"nctId":138,"briefTitle":139,"officialTitle":140,"acronym":141,"eligibilityCriteria":142,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":143,"targetDuration":4,"studyType":21,"phases":145,"briefSummary":146,"conditions":147,"keywords":151,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":155,"lastUpdatePostDateStruct":156,"startDateStruct":158,"completionDateStruct":160,"leadSponsor":162,"locationsCount":47},"100606240","the-value-of-standardized-respiratory-rate-monitoring-exercises-during-rheumatological-injection-procedures-100606240","NCT07172984","The Value of Standardized Respiratory Rate Monitoring Exercises During Rheumatological Injection Procedures","The Value of Standardized Respiratory Rate Monitoring Exercises During Rheumatological Infiltration Procedures - A Single-blind, Randomized, Controlled Non-inferiority Study","Respi-IR","Inclusion Criteria:\n\n* Patient scheduled to undergo therapeutic ultrasound-guided joint or periarticular injection.\n* Patient able to sign an informed consent form to participate in the study\n\nExclusion Criteria:\n\n* Patient able to sign an informed consent form to participate in the study - - Allergy to the injection product or anesthetic.\n* Injection not allowing the use of a local anesthetic due to insufficient joint volume (e.g., fingers\u002Ftoes).\n* Epidural injection via the sacrococcygeal hiatus.\n* Pregnant women",{"count":144,"type":20},136,[23],"The goal of this clinical trial is to demonstrate the non-inferiority of standardized breathing control exercises on perceived pain during rheumatological injections procedures compared to standard care consisting of the addition of a local anesthetic. The study population will consist of patients scheduled to undergo therapeutic ultrasound-guided joint or periarticular injection. The main question it aims to answer is:\n\n* Non-inferiority of breathing exercises compared to the addition of local anesthetic on pain and anxiety experienced during an infiltration procedure.\n* Correlation between the reduction in pain and anxiety experienced during a procedure and the cardiac coherence score obtained.\n\nResearchers will compare the anesthesia group (Arm A), which will receive local anesthesia with 5 cc of lidocaine before the infiltration procedure to the breathing group (Arm B), which will receive instructions before the injection procedure on how to perform 5-minute breathing cycles to facilitate the achievement of cardiac coherence to see if the pain perceived in Arm B is not greater than the pain perceived in Arm A.\n\nParticipants will be kept blind to their randomization group. Arm A (anesthesia) will receive SHAM breathing exercises, while Arm B (breathing) will receive a placebo injection of anesthetic.",[148,149,150],"Rheumatological Injection","Pain Management","Respiratory Monitoring",[152,153,154],"rheumatological injection","local anesthesia during intra-articular injection","respiratory rate monitoring","2025-12-30",{"date":157,"type":39},"2026-01-05",{"date":159,"type":39},"2025-09-19",{"date":161,"type":20},"2028-09-20",{"name":45,"class":46},{"id":164,"slug":165,"hasResults":11,"nctId":166,"briefTitle":167,"officialTitle":168,"acronym":169,"eligibilityCriteria":170,"healthyVolunteers":56,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":171,"targetDuration":4,"studyType":21,"phases":172,"briefSummary":173,"conditions":174,"keywords":176,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":180,"lastUpdatePostDateStruct":181,"startDateStruct":183,"completionDateStruct":185,"leadSponsor":187,"locationsCount":47},"100608901","evaluation-of-physiological-and-psychological-factors-involved-in-exercise-intolerance-in-patients-with--ttd-100608901","NCT07207577","Evaluation of Physiological and Psychological Factors Involved in Exercise Intolerance in Patients With β-TTD","Evaluation of Physiological and Psychological Factors Involved in Exercise Intolerance in Patients With Transfusion-dependent β-thalassemia","THALEX","Inclusion Criteria:\n\n* Patients aged 18 years or older\n\n  * Patients with transfusion-dependent β-thalassaemia (B0 or B+)\n  * Patients who have undergone blood transfusions at intervals of between 1 and 8 weeks for at least 5 years.\n  * Have given their free and informed written consent after being informed of the purpose of the study, its conduct and its risks.\n  * Be affiliated with a social security scheme.\n  * Not participating in any other interventional studies during the duration of this study\n\nControl subjects must meet all of the following criteria to participate in the study:\n\n* Subject aged 18 years or older\n* Matched in age and gender to a βTTD patient included in the study.\n* Declaring to be free of known acute or chronic pathologies.\n* Have given their free written consent after being informed of the purpose of the study, its conduct and its risks.\n* Be affiliated with a social security scheme.\n* Not participate in any other interventional study during the duration of this study.\n* Have 'low' or 'moderate' IPAQ results (inactive or slightly active).\n\nExclusion Criteria:\n\n* \\- Having received a bone marrow transplant.\n* History of thromboembolic disease.\n* Hospitalised for cardiac decompensation in the last 12 months.\n* Lack of use of limbs (amputee, paraplegic, quadriplegic)\n* Unable to comply with protocol requirements for social, family or other reasons, as determined by the investigator.\n* Known concomitant medical condition that could affect compliance with the protocol\n* benefiting of enhanced protection, namely minors, persons deprived of their liberty by judicial or administrative decision, adults under legal protection and, finally, patients in emergency situations.\n* Unable to give consent.\n* Pregnant or breastfeeding women.",{"count":118,"type":20},[23],"The goal of this clinical trial is to compare physical ability of patients with transfusion-dependent β-thalassemia to control subjects. The main question it aims to answer is:\n\nis there a difference in power output at first lactate threshold between patients with transfusion-dependent β-thalassemia and control subjects during maximal incremental exercise test.\n\nParticipants will have to realise differents exams including measurement of body compposition, maximal incremental exercise test, vertical jump, vasoreactivity test, blood sampling, quality of life questionnaires and neuromuscular assessments.",[175],"Beta Thalassemia Transfusion Dependent",[177,178,179],"physical ability","Beta thalassemia transfusion dependent","control subjects","2025-09-26",{"date":182,"type":39},"2025-10-06",{"date":184,"type":39},"2025-09-04",{"date":186,"type":20},"2028-10",{"name":45,"class":46},{"id":189,"slug":190,"hasResults":11,"nctId":191,"briefTitle":192,"officialTitle":193,"acronym":194,"eligibilityCriteria":195,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":196,"targetDuration":4,"studyType":21,"phases":198,"briefSummary":199,"conditions":200,"keywords":4,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":205,"lastUpdatePostDateStruct":206,"startDateStruct":208,"completionDateStruct":210,"leadSponsor":212,"locationsCount":47},"100537164","effect-of-sarcopenia-on-the-occurrence-of-toxicity-related-to-anti-cancer-treatments-100537164","NCT06274268","Effect of Sarcopenia on the Occurrence of Toxicity Related to Anti-cancer Treatments","Effect of Sarcopenia on the Occurrence of Toxicity Related to Anti-cancer Treatments. Prospective Cohort Study","SARC-ONCO","Inclusion Criteria:\n\n* Patients over 18 years old\n* Patient with a diagnosis of a histologically proven solid malignant tumor with an indication for systemic treatment during initial treatment.\n* CT\u002FPET performed within 45 days before initiation of systemic treatment.\n* Patient able to sign informed consent for participation in the study\n* Patient affiliated to a social security system\n\nExclusion Criteria:\n\n* History of cancer in the five years preceding inclusion other than localized skin or cervical cancers.\n* Patient with cancer not requiring systemic treatment.\n* Pregnant women.\n* Patient with a pace maker or defibrillator\n* Patient deprived of liberty or benefiting from a legal protection measure",{"count":197,"type":20},700,[23],"The goal of this clinical trial is to learn about the effect of sarcopenic status on the occurrence of treatment-related toxicity during the first course of anti-cancer treatment in several types of cancers.\n\nThe main question it aims to answer is :\n\nIs sarcopenia a predictive marker for the occurrence of toxicity in the initial phase of cancer treatment?\n\nThe evaluation will focus on the body composition of the participants, assessed by impedancemetry, and on their muscular performance by standardized physical tests.",[201,202,203,204],"Sarcopenia","Oncology","Physical Inactivity","Toxicity Due to Chemotherapy","2024-07-17",{"date":207,"type":39},"2024-07-18",{"date":209,"type":39},"2024-06-24",{"date":211,"type":20},"2028-05-01",{"name":45,"class":46},{"id":214,"slug":215,"hasResults":11,"nctId":216,"briefTitle":217,"officialTitle":218,"acronym":219,"eligibilityCriteria":220,"healthyVolunteers":11,"sex":221,"minAge":17,"maxAge":4,"enrollmentInfo":222,"targetDuration":4,"studyType":21,"phases":224,"briefSummary":225,"conditions":226,"keywords":4,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":228,"lastUpdatePostDateStruct":229,"startDateStruct":231,"completionDateStruct":233,"leadSponsor":235,"locationsCount":47},"100503289","prospective-study-of-detection-of-sarcopenia-in-clinical-practice-for-patient-with-ovarian-or-endometrial-cancer-100503289","NCT05833321","Prospective Study of Detection of Sarcopenia in Clinical Practice for Patient With Ovarian or Endometrial Cancer","Prospective Monocentric Study of the Detection of Sarcopenia in Clinical Practice in Patients With Ovarian or Endometrial Cancer Requiring Systemic Oncological Treatment","SARCO-GYN","Inclusion Criteria:\n\n* Patients at least 18 years old\n* Patient presenting with a diagnosis of cancer of ovarian origin with an indication for chemotherapy\n* Patient with a diagnosis of endometrial cancer with an indication for chemotherapy\n* Patient with no diagnosis of other types of cancer in the previous five years\n* Collection of consent\n* Patient affiliated to a Social Security scheme\n\nExclusion Criteria:\n\n* Patient with cancer of ovarian origin not requiring chemotherapy treatment\n* Patient with endometrial cancer not requiring chemotherapy treatment\n* Discovery of an intercurrent cancer other than skin or cervix cancers.\n* Patient wearing a Pace maker","FEMALE",{"count":223,"type":20},75,[23],"Prospective monocentric study, non-randomized of the detection of sarcopenia in clinical practice in patients with ovarian or endometrial cancer requiring systemic oncological treatment.\n\nmain question : Identify the criteria correlated with the presence of sarcopenia (defined by the measurement of the IMS by the CT-X method in L3) among the impedancemetry and the HAS malnutrition criteria.\n\nData collection will be done at 6 months, 12 months after the date of inclusion.",[227,201],"Ovarian Neoplasms","2023-06-29",{"date":230,"type":39},"2023-07-03",{"date":232,"type":39},"2022-11-20",{"date":234,"type":20},"2026-10",{"name":45,"class":46},""]