[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Centre Hospitalier de Valenciennes\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":187},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,6,0,[8,47,76,106,134,160],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":29,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":35,"lastUpdatePostDateStruct":36,"startDateStruct":39,"completionDateStruct":41,"leadSponsor":43,"locationsCount":46},"100639702","pilot-study-on-the-use-of-video-laryngoscopy-in-pre-hospital-settings-100639702",false,"NCT07630467","Pilot Study on the Use of Video Laryngoscopy in Pre-hospital Settings","Pilot Study on the Use of Video Laryngoscopy in Pre-hospital Settings: Evaluation of the Success Rate of Intubation on the First Attempt, Highlighting Criteria Specific to the Patient, the Practitioner and the Environment That May Influence This Rate.","VIDEOPREHOSP","Patient Inclusion Criteria:\n\n* Age \\> 18 years\n* Patients treated pre-hospital by a team from the Emergency Medical and Resuscitation Service (SMUR) at Valenciennes Hospital 2025-A02374-45\\_SUMMARY\\_v1.1 dated 04\u002F12\u002F2025 \\_VIDEOPREHOSP Page 3 of 4\n* Patients whose condition requires pre-hospital orotracheal intubation\n* Patient or relative who has given consent for inclusion\n* Patient affiliated with a social security scheme\n\nPratician Inclusion Criteria :\n\n* Practitioner at Valenciennes Hospital\n* Practitioner who is part of the EMS team\n\nExclusion Criteria:\n\n* Progressive pregnancy\n* Theoretical indication for orotracheal intubation but patient refuses invasive care, considered in this situation to be futile medical care\n* Insurmountable anatomical obstacle, in which case an emergency cricothyroidotomy or tracheotomy should be considered as the first line of treatment\n* Patients under guardianship or curatorship\n* Patients deprived of their liberty by court order","ALL","18 Years",{"count":20,"type":21},143,"ESTIMATED","INTERVENTIONAL",[24],"NA","Management of the upper airways is an essential skill in pre-hospital medicine in order to protect the respiratory tract and optimise ventilation and oxygenation. Orotracheal intubation remains the gold standard method in this context. In France, approximately 8% of primary SMUR interventions require intubation, representing 40,000 to 50,000 procedures per year, 30 to 40% of which are performed on patients in cardiorespiratory arrest.\n\nDespite an overall success rate of nearly 99%, 8 to 15% of intubations are considered difficult and the success rate on the first attempt is only 77.8%. Difficult intubations expose patients to significant complications, including desaturation (nearly 50% of cases), haemodynamic disorders and, more rarely, cardiopulmonary arrest (3% of cases). Pre-hospital conditions (environment, access to the patient, trauma, secretions, etc.) increase these risks. As a result, recent recommendations now consider any emergency intubation outside the operating theatre to be potentially difficult.\n\nThe introduction of video laryngoscopy represents a major technological advance. Its superiority has been demonstrated in hospital settings, particularly for difficult intubations, and it is now recommended as the first-line treatment in this context. However, unlike in the United States, where several studies suggest that it is safer and more effective than direct laryngoscopy, there are no specific recommendations or French studies concerning its use in pre-hospital medicine.\n\nGiven these factors and the lack of national data, it seems appropriate to conduct an exploratory French study to assess the place, effectiveness, benefits and constraints of video laryngoscopy in a pre-hospital setting. Investigator hypothesises that the success rate for the first attempt at intubation using video laryngoscopy will be 74%.",[27,28],"Emergency","Orotracheal Intubation",[30,31,32,33],"orotracheal intubation","pre-hospital","first attempt","videolaryngoscopy","RECRUITING","2026-06-03",{"date":37,"type":38},"2026-06-05","ACTUAL",{"date":40,"type":38},"2026-01-02",{"date":42,"type":21},"2026-12-02",{"name":44,"class":45},"Centre Hospitalier de Valenciennes","NETWORK",1,{"id":48,"slug":49,"hasResults":11,"nctId":50,"briefTitle":51,"officialTitle":51,"acronym":52,"eligibilityCriteria":53,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":54,"targetDuration":56,"studyType":57,"phases":4,"briefSummary":58,"conditions":59,"keywords":63,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":68,"lastUpdatePostDateStruct":69,"startDateStruct":71,"completionDateStruct":73,"leadSponsor":75,"locationsCount":46},"100623258","study-of-the-prevalence-of-midline-replacements-and-the-reasons-for-these-replacements-100623258","NCT07394296","Study of the Prevalence of Midline Replacements and the Reasons for These Replacements","MIDRELAY","Inclusion Criteria:\n\n* Patients over 18 years of age.\n* Patients who have given their consent to participate in the study.\n* Patients treated in a hospital unit authorized to insert midlines, or who have a midline inserted by a professional trained in this procedure, in accordance with the local organization of each center.\n* First insertion for the treatment of a given event with an expected treatment duration of 28 days or less.\n* Patients treated with a midline catheter at least 14 cm in length.\n\nExclusion Criteria:\n\n* No coverage by the social security system\n* Failure to insert the midline\n* Patient under guardianship or conservatorship",{"count":55,"type":21},984,"33 Days","OBSERVATIONAL","Venous access management plays a key role in patient care and preserving their venous capital. The so-called \"conventional\" peripheral venous catheter is the most common venous access device, but it is associated with a high rate of complications, particularly in cases of prolonged use or poor venous capital. Recommendations, such as those from MAGIC or SF2H, advocate their use when the intended duration of use is 5 days or less. For longer periods or in cases of difficult access, so-called \"central\" devices such as PICC lines or central venous catheters are used, although they present specific risks such as CLASBI or deep vein thrombosis.\n\nIn intermediate situations, the midline, a peripheral venous access device, is a relevant alternative, particularly for non-venotoxic intravenous treatments lasting more than 5 days. Although it is theoretically associated with fewer infections and complications than the PICCline, its complication rate and actual duration of use vary widely in the literature.\n\nThe MAGIC recommendations suggest using them for periods of 14 days or less. The widespread use of midlines in healthcare facilities, and in particular the creation of vascular access units, has given rise to issues shared between centers, notably the replacement rate of these devices. The study therefore aims to determine the replacement and early removal rates for midlines, the circumstances in which they are replaced, and toassess the relevance of the 28-day limit in the choice of device, in order to improve practices and optimize the practitioner's initial decision.",[60,61,62],"Veinous Access","Midline","Veinous Capital",[64,65,66,67],"midline","midline placement","midline indication","patient care","2026-02-06",{"date":70,"type":38},"2026-02-10",{"date":72,"type":38},"2025-12-02",{"date":74,"type":21},"2027-01-05",{"name":44,"class":45},{"id":77,"slug":78,"hasResults":11,"nctId":79,"briefTitle":80,"officialTitle":81,"acronym":82,"eligibilityCriteria":83,"healthyVolunteers":11,"sex":84,"minAge":4,"maxAge":4,"enrollmentInfo":85,"targetDuration":4,"studyType":22,"phases":87,"briefSummary":88,"conditions":89,"keywords":93,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":98,"lastUpdatePostDateStruct":99,"startDateStruct":101,"completionDateStruct":103,"leadSponsor":105,"locationsCount":46},"100592593","breast-cancer-and-chemobrain--effects-of-photobiomodulation-on-the-improvement-of-perceived-cognitive-impairment-100592593","NCT06995443","Breast Cancer and Chemobrain : Effects of Photobiomodulation on the Improvement of Perceived Cognitive Impairment","Breast Cancer and Chemobrain : Effects of Photobiomodulation on the Improvement of Perceived Cognitive Impairment - REGAIN","REGAIN","Inclusion Criteria:\n\n* Women aged 18 and over\n* Having completed chemotherapy (intravenous) for breast cancer (any stage) less than 12 months prior to inclusion\n* Having a perceived cognitive complaint that appeared during or after (\\\u003C 3 months) chemotherapy treatments (no restriction on the care protocol used) and confirmed by a FACT-Cog score compatible with a subjective cognitive disorder (score \\\u003C 117 for patients aged 18 to 49; score \\\u003C 113 for patients aged 50 to 69; score \\\u003C105 for patients aged 70 and over)\n* Patient eligible for photobiomodulation sessions\n* Patient with sufficient command of the French language to complete the study questionnaries\n* Patient having given written consent to participate in the trial\n* Socially insured patient\n* Patient willing to comply with all study procedures and duration\n\nExclusion Criteria:\n\n* Known cognitive disorders prior to chemotherapy treatment\n* Patients with psychiatric or psychobehavioral disorders incompatible with photobiomodulation sessions\n* Patients who, in the 12 months prior to inclusion or at the time of inclusion, have already received photobiomodulation treatment involving \"whole body\" therapy (photobiomodulation in a phototherapy booth).\n* Patient having previously received photobiomodulation with cortical stimulation (panel or helmet) with no time limit.\n* Patient taking or having received capecitabine\n* Patients taking part in a protocol involving a drug likely to affect cognitive performance (on the investigator's advice).\n* Patients suffering from claustrophobia\n* Patient unable to read and\u002For unable to complete a questionnaire, in the opinion of the investigator","FEMALE",{"count":86,"type":21},200,[24],"Breast cancer is one of the most common cancers in metropolitan France, with over 60,000 new cases in 2023. Mostly a female cancer, it can affect a young population, with around 20% of breast cancers occurring in women under 50. Treatment is mainly based on surgery, chemotherapy, radiotherapy, targeted therapies and hormone therapy. Although chemotherapy is not systematically used, it remains a frequent treatment option. While chemotherapy makes a major contribution to curing cancer, it is also a source of potentially disabling side effects for survivors.\n\nChemotherapy can interfere with the normal functioning of the central nervous system, leading to cognitive impairment. The number of people potentially affected by chemobrain is estimated at several tens of millions worldwide. There is no recommended treatment for people with chemobrain. Several avenues have been explored, with very limited results. Photobiomodulation (PBM) is a non-medicinal treatment technique that combines all the biological, athermic and non-cytotoxic effects of tissue exposure to non-ionizing sources of red and infrared light. Several studies have demonstrated the beneficial effects of cortical stimulation by photobiomodulation on memory (increased angiogenesis, increased oxygenation of brain tissue via vasodilatation, and increased mitochondrial ATP production). These positive biological effects are likely to ameliorate the undesirable effects of chemotherapy, and consequently the post-chemotherapy cognitive disorders that ensue.",[90,91,92],"Oncology","Support Care","Cognitive Disorders",[94,95,96,97],"Cognitive disorders","Photobiomodulation","Breast cancer","oncology","2026-01-29",{"date":100,"type":38},"2026-01-30",{"date":102,"type":38},"2025-06-13",{"date":104,"type":21},"2027-12",{"name":44,"class":45},{"id":107,"slug":108,"hasResults":11,"nctId":109,"briefTitle":110,"officialTitle":111,"acronym":112,"eligibilityCriteria":113,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":114,"targetDuration":4,"studyType":22,"phases":116,"briefSummary":117,"conditions":118,"keywords":120,"overallStatus":127,"whyStopped":4,"lastUpdateSubmitDate":98,"lastUpdatePostDateStruct":128,"startDateStruct":129,"completionDateStruct":131,"leadSponsor":133,"locationsCount":4},"100594010","audiovisual-distraction-in-intensive-care-100594010","NCT07013877","Audiovisual Distraction in Intensive Care","Evaluation of the Impact of the Use of RELAX Glasses on Patients' Anxiety During Invasive Care in Intensive Care, Post-operative Intensive Care and Continuous Monitoring","DARE","Inclusion Criteria:\n\n* Patients hospitalized in intensive care, post-operative intensive care and continuous monitoring;\n* Patient receiving invasive care placement of peripheral venous line, nasogastric tube insertion, bladder catheterization, dressing stage IV pressure sores, heavy dressing lasting \\> 15 minutes arterial gasometry by puncture;\n* Patient of legal age;\n* Patient with written consent;\n* Patient with Glasgow score equal to 15;\n* Socially insured patient;\n* Patient willing to comply with all study procedures and duration.\n\nExclusion Criteria:\n\n* Medical history contraindicating RELAX eyewear;\n* Known and current abuse of alcohol and\u002For illicit drugs that may interfere with patient safety and\u002For compliance;\n* Any condition that would make the patient unsuitable for the study: current presence of cognitive disorders (MMS \\\u003C 15), severe psychiatric disorders (bipolar disorders, psychotic disorders according to DSM-V classification);\n* Major anxiety requiring anxiolytic medication prior to invasive care;\n* Patient under court protection;\n* Patient participating in another study;\n* Patient who has already participated in the DARE study.\n* Patient's refusal to use glasses;\n* Visually impaired or blind patient.",{"count":115,"type":21},456,[24],"Resuscitation patients are subject to constant stress of multifactorial origin: their state of health, the noisy environment of critical care, the multiple examinations and care provided, lack of sleep, stress from their loved ones... It is estimated that 60% of resuscitation patients have experienced stress and 40% have been anxious during their hospitalization in intensive care. This permanent anxiety is punctuated by stress peaks, particularly at the time of invasive procedures frequently performed in the ICU.\n\nThis stress is said to have a negative impact on patients' ability to recover and on their length of stay in the ICU. What's more, these anxious symptoms can persist after hospitalization, leading to post-traumatic stress disorder. It therefore seems appropriate to find solutions aimed at reducing this stress.\n\nMedication is often used to reduce stress and anxiety. Although effective, these molecules have undesirable side-effects and can also hinder the patient's recovery.\n\nAlternative methods are already being studied as replacement or supplementary therapies to drugs. These include music therapy, aromatherapy, hypnosis and virtual reality.\n\nVirtual reality has been used on resuscitation patients to improve tolerance to mechanical ventilation and to the resuscitation environment in general.",[119],"Anxiety",[121,122,123,124,125,126],"Audiovisual sedation","anxiety","resuscitation","post-operative intensive care","invasive care","continuous monitoring","NOT_YET_RECRUITING",{"date":100,"type":38},{"date":130,"type":21},"2026-07",{"date":132,"type":21},"2028-10",{"name":44,"class":45},{"id":135,"slug":136,"hasResults":11,"nctId":137,"briefTitle":138,"officialTitle":139,"acronym":140,"eligibilityCriteria":141,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":142,"targetDuration":4,"studyType":22,"phases":144,"briefSummary":145,"conditions":146,"keywords":148,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":152,"lastUpdatePostDateStruct":153,"startDateStruct":155,"completionDateStruct":157,"leadSponsor":159,"locationsCount":46},"100537494","psychological-factors-influencing-cancer-post-traumatic-growth-100537494","NCT06278558","Psychological Factors Influencing Cancer Post-traumatic Growth","Study of the Psychological Factors Influencing Post-traumatic Growth During Oncological Pathway","CEMA-P","Inclusion Criteria:\n\n* Patients over 18 years of age\n* Patients in the initial phase of curative treatment for a 1st solid cancer\n* At the start of neo-adjuvant or adjuvant chemotherapy (1st course or 2nd course)\n* At less than 6 months from the initial diagnosis\n* Patient having given written consent to participate in the study\n\nExclusion Criteria:\n\n* Patients with a previous history of cancer\n* Patients with incurable cancer progression, recurrence or relapse\n* Metastatic, brain, hematological or skin cancer\n* Patients who have difficulty understanding written French\n* Patient psychologically or physically unable to answer questionnaires",{"count":143,"type":21},289,[24],"The study focuses on post-traumatic growth (positive changes linked to appreciation of life, personal strengths, social relationships...) in the context of different types of cancer and with a longitudinal approach to the care pathway. The aim of the study is to better understand whether psychological variables (emotional competence, psychological flexibility, psychological distress) and patients' care satisfaction, assessed at the start of the cancer treatment pathway, can influence their post-traumatic growth at the end of the chemotherapy protocol and 6 months later.",[147],"Cancer",[147,149,150,151],"Post-traumatic growth","Emotional competence","Emotional distress","2025-03-19",{"date":154,"type":38},"2025-03-24",{"date":156,"type":38},"2023-11-10",{"date":158,"type":21},"2027-11-10",{"name":44,"class":45},{"id":161,"slug":162,"hasResults":11,"nctId":163,"briefTitle":164,"officialTitle":165,"acronym":166,"eligibilityCriteria":167,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":168,"targetDuration":4,"studyType":22,"phases":170,"briefSummary":171,"conditions":172,"keywords":174,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":179,"lastUpdatePostDateStruct":180,"startDateStruct":182,"completionDateStruct":184,"leadSponsor":186,"locationsCount":46},"100565202","from-administration-of-oral-medicines-by-nurses-to-controlled-self-administration-impact-on-safety-of-administration-during-hospitalisation-100565202","NCT06639113","From Administration of Oral Medicines by Nurses to Controlled Self-administration: Impact on Safety of Administration During Hospitalisation","Evaluation of the Safety of a Change of Practice in the Administration of Oral Medication During Hospitalisation: From Administration by the Nurse to Supervision of Self-administration of Medication in the Locomotor and Polyvalent Rehabilitation Department of the Valenciennes Hospital Centre.","AUTOGESTMED","Inclusion Criteria:\n\n* Care in the rehabilitation unit of Hospital in Valenciennes, France\n* Patient with a planned stay of 7 days or more\n* Patient on chronic treatment before admission to hospital ;\n* Patients taking their treatment alone at home;\n\nExclusion Criteria:\n\n* Age \\\u003C 18 years old\n* Patients with poor compliance\n* No chronic treatment\n* Unstable disease\n* Major cognitive, memory or depressive disorders\n* Swallowing disorders\n* Prehension problems\n* Patient under legal protection\n* Patient under guardianship or curatorship\n* Patient included in another trial",{"count":169,"type":21},192,[24],"Medication administration practices during patient hospital stay tend to improve patient autonomy. Several studies have concluded that self-administration of medication programs in hospital centers have a beneficial effect on patients' knowledge of their medications, their compliance and the safety of administration. Nevertheless, few studies have been carried out in France on this subject. The aim of this study is to evaluate the impact of the change of nurses administration practices from the administration of each drugs to supervision of self-administration by the patient under a self-administration program.",[173],"Self Administration",[175,176,177,178],"Rehabilitation","Self-management of medication","Administration","Autonomy","2024-10-11",{"date":181,"type":38},"2024-10-15",{"date":183,"type":38},"2024-05-24",{"date":185,"type":21},"2026-05",{"name":44,"class":45},""]