[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Centre Mutualiste de Rééducation et de Réadaptation Fonctionnelles de Kerpape\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":146},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,5,0,[8,47,68,102,124],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":14,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":29,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":35,"lastUpdatePostDateStruct":36,"startDateStruct":39,"completionDateStruct":41,"leadSponsor":43,"locationsCount":46},"100625165","trunk-impairment-scale---adaptation-and-validation-in-french-100625165",false,"NCT07419087","Trunk Impairment Scale - Adaptation and Validation in French","KER-TIS fr","Inclusion criteria (Phase 1):\n\n* Patients over 18 years of age\n* Patients who have had a stroke\n* Full understanding of the French language\n* No cognitive disorders\n* No prior exposure to the TIS scale\n* Covered by a social security system\n* Having been informed, having agreed to participate in the study, and having signed the free and informed consent form.\n\nInclusion criteria (Phase 2):\n\n* Patients aged over 18 and under 85 years\n* Having had a stroke, with no time-since-onset limitation\n* Able to sit for 10 seconds without hand support\n* Able to provide informed consent\n* With an NIHSS score between 2 and 26\n* Covered by a social security system\n* Having been informed, having agreed to participate in the study, and having signed the free and informed consent form\n\nExclusion Criteria (Phase 1):\n\n* Insufficient command of the French language\n* Inability to understand instructions\n* Persons deprived of liberty (by judicial or administrative decision)\n* Adults under legal protection or unable to express their consent\n* Pregnant or breastfeeding women\n\nExclusion Criteria (Phase 2):\n\n* Contraindication to the sitting position or to hip adduction (hip prosthesis)\n* History of orthopedic or neurological disorders affecting sitting balance\n* Insufficient command of the French language\n* Inability to understand instructions\n* Person deprived of liberty (by judicial or administrative decision)\n* Adult under legal protection or unable to express consent\n* Pregnant or breastfeeding woman","ALL","18 Years","85 Years",{"count":20,"type":21},67,"ESTIMATED","INTERVENTIONAL",[24],"NA","The objective of this project is to verify the validity and determine the clinimetric properties after translation and adaptation into French of the Trunk Impairment Scale (TIS), a scale for measuring trunk control and seated balance.",[27,28],"Stroke (CVA) or Transient Ischemic Attack","Stroke (CVA) or TIA",[30,31,32,33],"traduction","Trunk Impairment Scale","TIS","post-stroke","RECRUITING","2026-06-22",{"date":37,"type":38},"2026-06-24","ACTUAL",{"date":40,"type":38},"2026-03-19",{"date":42,"type":21},"2028-07-19",{"name":44,"class":45},"Centre Mutualiste de Rééducation et de Réadaptation Fonctionnelles de Kerpape","OTHER",1,{"id":48,"slug":49,"hasResults":11,"nctId":50,"briefTitle":51,"officialTitle":51,"acronym":52,"eligibilityCriteria":53,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":54,"targetDuration":4,"studyType":56,"phases":4,"briefSummary":57,"conditions":58,"keywords":4,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":60,"lastUpdatePostDateStruct":61,"startDateStruct":63,"completionDateStruct":65,"leadSponsor":67,"locationsCount":46},"100631154","identification-of-responders-to-platelet-rich-plasma-prp-injections-in-lateral-elbow-epicondylalgia-100631154","NCT07496983","Identification of Responders to Platelet-Rich Plasma (PRP) Injections in Lateral Elbow Epicondylalgia","EPIC-PRP","Inclusion Criteria:\n\n* Age ≥ 18 years\n* Chronic lateral epicondylalgia (tennis elbow), diagnosed clinically or by imaging (ultrasound or MRI), evolving for more than 3 months\n* PRP injection received within the last 48 hours\n* Medically stable\n* Able to provide informed consent\u002Fnon-opposition\n* Affiliation to a social security system\n\nExclusion Criteria:\n\n* PRP injection received more than 48 hours before inclusion\n* Participation in another clinical study with exclusion period\n* Adults under legal protection\n* Pregnant women",{"count":55,"type":21},139,"OBSERVATIONAL","The goal of this non-interventional study is to identify patients who respond to platelet-rich plasma (PRP) injections for chronic lateral epicondylalgia (tennis elbow) and to investigate factors associated with treatment response. The study will include approximately 139 adults (18 years and older) with chronic lateral elbow pain who received a PRP injection within the last 48 hours.\n\nThe main question it aims to answer is:\n\nHow many patients respond to PRP treatment for chronic lateral epicondylalgia at 90 days after injection?\n\nSecondary questions include:\n\nWhich clinical, demographic, and occupational factors are associated with response to PRP?\n\nCan a predictive model be developed to identify patients likely to respond to PRP?\n\nHow do pain, hand grip strength, and functional outcomes evolve over 90 days in responders versus non-responders?\n\nParticipants will:\n\nAttend three visits at baseline (Day 0), Day 45, and Day 90.\n\nUndergo clinical examinations, pain assessments (EVA, DN4), functional tests (hand grip, PRTEE), and questionnaires.\n\nHave data on professional activities, medical history, and treatments collected.\n\nAll procedures are part of routine care, except for the addition of the Clinical Global Impression - Change (CGI-C) scale at Day 45 and Day 90 to assess treatment response.\n\nThe study will be conducted at the CMRRF de Kerpape and the CHU de Rennes in France. Each participant will be followed for approximately 3 months.",[59],"Lateral Epicondylitis of the Elbow","2026-03-25",{"date":62,"type":38},"2026-03-27",{"date":64,"type":38},"2023-08-04",{"date":66,"type":21},"2026-08",{"name":44,"class":45},{"id":69,"slug":70,"hasResults":11,"nctId":71,"briefTitle":72,"officialTitle":72,"acronym":73,"eligibilityCriteria":74,"healthyVolunteers":75,"sex":76,"minAge":77,"maxAge":4,"enrollmentInfo":78,"targetDuration":4,"studyType":22,"phases":80,"briefSummary":81,"conditions":82,"keywords":88,"overallStatus":93,"whyStopped":4,"lastUpdateSubmitDate":94,"lastUpdatePostDateStruct":95,"startDateStruct":97,"completionDateStruct":99,"leadSponsor":101,"locationsCount":46},"100626106","ecological-test-standardization-for-concussion-assessment-in-football-players-100626106","NCT07431320","Ecological Test Standardization for Concussion Assessment in Football Players","COMOFOOT","Inclusion Criteria:\n\nProfessional football players:\n\n* Male professional football players from French clubs\n* Aged 18 years and older\n* Provided written informed consent to participate\n* Adequate understanding of written and spoken French\n\nYouth football players from training centers:\n\n* Registered in a training center affiliated with a French football club\n* Aged 16 years and older\n* Provided written assent to participate, with parental or legal guardian consent for minors\n* Adequate understanding of written and spoken French\n\nExclusion Criteria:\n\nAll players:\n\n* History of concussion in the past 6 months (for inclusion, a statement from the club physician confirming no concussion in the past 6 months will be requested)\n* Physically unfit (if applicable, a medical certificate from the club physician will be required, e.g., incapacitating musculoskeletal injury)",true,"MALE","16 Years",{"count":79,"type":21},100,[24],"Concussion is a major concern in the sports world. It represents an immediate and transient alteration of neurological functions due to a direct or indirect trauma, with or without loss of consciousness. Concussions affect between 1.6 and 3.8 million people per year in the United States across all sports. The prevalence varies depending on the sport. In France, the incidence of sport-related concussions is estimated at 200,000 cases. According to the French Academy of Medicine (March 2025), concussions account for between 5% and 9% of all sports-related injuries. Among these cases, 30% involve individuals aged 5 to 19. Football (soccer) is one of the most affected sports, with its 2 million registered players. In French professional football (Ligue 1 and 2), during the 2023-2024 season, one concussion was recorded every 55 matches on average (declared concussion). During the 2018-2019 and 2019-2020 seasons, the rate of matches with concussion was approximately 2.5%. In professional rugby, it is estimated that one concussion occurs every three matches in France.\n\nThere are no precise statistics on the number or frequency of concussions in amateur football in France, due to a lack of reporting and insufficient diagnosis. Currently, practical recommendations exist for managing football players from the moment of impact on the field, implemented within the French Football Federation. The current concussion protocol includes a standardized tool for evaluating concussion intended for healthcare professionals, the SCAT6. However, this protocol is not always sufficient, and return-to-play sometimes occurs too early. Indeed, current assessments are too brief and do not evaluate all cognitive functions. They do not allow a clear understanding of the real on-field consequences. It is estimated that 50% of athletes return to play too early after a concussion, with risks of neurological complications or prolonged symptoms.\n\nHowever, defining rest time and return-to-play criteria is not straightforward. In practice, return to play relies, among other things, on neuropsychological tests, whose interpretation is difficult in the absence of baseline data. The concussion protocol does not allow for an accurate determination of whether performance has normalized without this neuropsychological baseline.\n\nRecent European and international recommendations advise conducting pre-season assessments to provide comparative values. Several studies have been published on the type of pre-season assessments to perform, most using paper-and-pencil or computerized neurocognitive tests.\n\nThe current concussion protocol relies mainly on paper-and-pencil tests. However, the literature shows dissociations between cognitive performance measured in ecological environments and performance measured through paper-and-pencil tests. Ecological tasks have the advantage of closely approximating the daily actions of a player and assessing cognitive functioning more precisely.\n\nThus, these ecological tasks, combined with a baseline assessment, would improve the evaluation of athletes following a concussion. These tasks would facilitate return-to-play decisions through more objective observations and normed data. Finally, ecological tasks would enhance player monitoring and allow a more accurate understanding of their health status.\n\nFor this reason, it seems necessary to develop a standardized ecological test performed in real-game situations. This would improve decision-making regarding return to play without medically endangering the player and would allow better understanding of the cognitive effects of concussion. These tasks will first be reviewed and tested by experts (players, football staff members, national concussion reference physician, and neuropsychologists) for feedback and refinement.",[83,84,85,86,87],"Concussion, Brain","Sports-related Concussion","Football Players","Traumatic Brain Injury, Mild","Healthy Volunteer Male Subjects",[89,90,91,92],"ecological test","reliability","standardization","cognitive assessments","NOT_YET_RECRUITING","2026-02-18",{"date":96,"type":38},"2026-02-24",{"date":98,"type":21},"2026-04",{"date":100,"type":21},"2028-04",{"name":44,"class":45},{"id":103,"slug":104,"hasResults":11,"nctId":105,"briefTitle":106,"officialTitle":107,"acronym":108,"eligibilityCriteria":109,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":110,"targetDuration":4,"studyType":22,"phases":112,"briefSummary":113,"conditions":114,"keywords":4,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":116,"lastUpdatePostDateStruct":117,"startDateStruct":119,"completionDateStruct":121,"leadSponsor":123,"locationsCount":46},"100441934","impact-of-compression-garments-on-pain-in-patients-with-complex-regional-pain-syndrome-of-the-upper-limbs-100441934","NCT05034835","Impact of Compression Garments on Pain in Patients With Complex Regional Pain Syndrome of the Upper Limbs.","Impact of Compression Garments on Neuropathic-looking Pain in Patients With Complex Regional Pain Syndrome (CRPS) of the Upper Limbs.","VECODON","Inclusion Criteria:\n\n* Patients with CRPS of the upper limb with neuropathic pain\n\n  * Diagnosis of CRPS according to the Budapest criteria\n  * Diagnosis of neuropathic pain according to DN4\n* CRPS evolving for more than 3 months\n* No phlebitis or open sores on the upper limbs\n* Patient consent to participate in the study\n* No modification of his drug treatment for 1 month\n* Affiliation to a social security scheme or beneficiary of such a scheme\n\nExclusion Criteria:\n\n* Patient under guardianship, curatorship or safeguard of justice\n* Psychiatric pathology altering the ability to consent\n* Severe cognitive disorders that do not allow the patient to assess his pain\n* Skin pathology preventing the wearing of the compression garment\n* Patient who has previously worn a compression garment\n* History of vascular disorders of the upper limbs, lymph node dissection, or any other pathology that can lead to edema regardless of CRPS\n* Known allergy to one of the components of the compression garments of the Cerecare brand\n* Declared pregnancy, breastfeeding woman or woman of childbearing potential without contraception\n* Inability to put on the compression garment alone",{"count":111,"type":21},60,[24],"The aim is to study another alternative for the treatment of pain in people with CRPS. Indeed, the TRAB \u002F Medullary occupational therapy department of the CMRRF in Kerpape used compression garments to reduce edema when it was present.In the case of CRPS of the upper limbs, gloves or compression sleeves are used to decrease the edema which is sometimes associated, although they are not supported for this indication. In this context, our clinical experience leads us to believe that there would also be some efficacy in neuropathic pain, this improvement being regularly described by patients.This study is expected to show a notable reduction in neuropathic pain thanks to the wearing of a compression garment.",[115],"Complex Regional Pain Syndromes","2025-10-01",{"date":118,"type":38},"2025-10-06",{"date":120,"type":38},"2021-10-12",{"date":122,"type":21},"2026-10",{"name":44,"class":45},{"id":125,"slug":126,"hasResults":11,"nctId":127,"briefTitle":128,"officialTitle":129,"acronym":130,"eligibilityCriteria":131,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":132,"targetDuration":4,"studyType":22,"phases":134,"briefSummary":135,"conditions":136,"keywords":138,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":139,"lastUpdatePostDateStruct":140,"startDateStruct":142,"completionDateStruct":143,"leadSponsor":145,"locationsCount":46},"100556824","promote-awareness-of-the-driving-abilities-of-post-stroke-patients-100556824","NCT06530134","Promote Awareness of the Driving Abilities of Post-stroke Patients.","Promote Awareness of the Driving Abilities of Post-stroke Patients: Interest of On-board Cameras and Self-assessment Questionnaires During a Driving Situation.","AUTOCAM-AVC","Inclusion Criteria:\n\n* Stroke (ischemic and \u002F or hemorrhagic) between 1 month and 6 months\n* Holder of a driving license for more than 3 years\n* No resumption of driving\n* MoCA score ≥ 10\n* Affiliation to a social security scheme or beneficiary of such a scheme\n* Having signed a free, informed and written consent\n* Medically stable\n\nExclusion Criteria:\n\n* Aphasia with severe comprehension disturbances, severe hemineglect, unstable epilepsy, severe visual disturbances (binocular vision \\\u003C6\u002F10, visual field \\\u003C120 ° in binocular, \\\u003C50 ° to the right and to the left beyond the central point, \\\u003C30 ° vertically.\n* History of neurological disease responsible for cognitive impairment\n* Need for vehicle modifications except automatic gearbox\n* Subject being in a period of exclusion from another protocol\n* Insufficient command of the French language\n* Protected adults (curators)\n* Pregnancy declared\n* Being unable to issue their consent",{"count":133,"type":21},70,[24],"Patients with cerebrovascular accident (CVA) may present with a deficit of awareness of the disorders which results in a lack of correct self-estimation of their own abilities and difficulties in terms of both cognition and driving. It is therefore important to develop tools to help professionals take this deficit into account in their driving assessments and also to help patients better identify their real abilities.\n\nThis research project thus proposes a protocol making it possible to promote decision-making whether or not to resume driving by multidisciplinary teams.\n\nThe main objective is to determine to what extent video feedback promotes awareness of the ability to manage post-stroke patients, compared to a group of control patients receiving the usual recommendations.",[137],"Cerebrovascular Accident",[33],"2024-07-27",{"date":141,"type":38},"2024-07-31",{"date":120,"type":38},{"date":144,"type":21},"2024-11",{"name":44,"class":45},""]