[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Centre de Recherche de l'Institut Universitaire de Cardiologie et de Pneumologie de Quebec\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":74},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,51],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":17,"sex":18,"minAge":19,"maxAge":4,"enrollmentInfo":20,"targetDuration":23,"studyType":24,"phases":4,"briefSummary":25,"conditions":26,"keywords":30,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":39,"lastUpdatePostDateStruct":40,"startDateStruct":43,"completionDateStruct":45,"leadSponsor":47,"locationsCount":50},"100373222","prospective-validation-of-a-pre-specified-algorithm-for-the-management-of-conduction-disturbances-following-tavr-100373222",false,"NCT04139616","Prospective Validation of a Pre-Specified Algorithm for the Management of Conduction Disturbances Following TAVR","Prospective Validation of a Pre-Specified Algorithm for the Management of Conduction Disturbances Following Transcatheter Aortic Valve Replacement. The PROMOTE Study","PROMOTE","Inclusion Criteria:\n\n-Patients with aortic valve disease undergoing transcatheter aortic valve replacement\n\nExclusion Criteria:\n\n* Prior permanent pacemaker\n* Failure to provide signed informed consent for data collection\n* Impossibility for a follow-up\n* Unwillingness to follow the pre-specified strategy for the management of conduction disturbances",true,"ALL","18 Years",{"count":21,"type":22},2000,"ESTIMATED","1 Year","OBSERVATIONAL","The high incidence and variety of conduction disturbances post-TAVR represents a major challenge in the periprocedural management of TAVR recipients. Despite the growing body of knowledge on this topic, the large variability in the management of these complications has translated into a high degree of uncertainty regarding the most appropriate treatment of a large proportion of such patients. The implementation of a pre-specified treatment strategy translating into a more uniform practice regarding the management of conduction disturbances post-TAVR applied to a large cohort of patients would permit to identify the benefits and drawbacks of each specific aspect of the treatment algorithm proposal. This may also help to improve both the management and clinical outcomes of the complex group of patients with conduction disturbances associated with TAVR. In the end, the final objective of a pre-specified strategy for managing conduction disturbances post-TAVR should be to obtain a low rate of PPM without increasing the risk of sudden death or life threatening arrhythmic events following hospital discharge, and all this while avoiding an excessive prolongation of the hospitalization period following the TAVR procedure.",[27,28,29],"Conduction Disturbances","Transcatheter Aortic Valve Replacement","Permanent Pacemaker Implantation",[31,32,33,34,35,36,37],"atrioventricular block","complete heart block","high-degree atrioventricular block","intraventricular conduction delay","left bundle branch block","Permanent pacemaker implantation","Right bundle branch block","RECRUITING","2026-05-28",{"date":41,"type":42},"2026-06-01","ACTUAL",{"date":44,"type":42},"2020-02-25",{"date":46,"type":22},"2027-12-25",{"name":48,"class":49},"Centre de Recherche de l'Institut Universitaire de Cardiologie et de Pneumologie de Quebec","OTHER",1,{"id":52,"slug":53,"hasResults":11,"nctId":54,"briefTitle":55,"officialTitle":55,"acronym":56,"eligibilityCriteria":57,"healthyVolunteers":17,"sex":18,"minAge":19,"maxAge":4,"enrollmentInfo":58,"targetDuration":4,"studyType":60,"phases":61,"briefSummary":63,"conditions":64,"keywords":4,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":66,"lastUpdatePostDateStruct":67,"startDateStruct":69,"completionDateStruct":71,"leadSponsor":73,"locationsCount":50},"100220916","ambulatory-electrocardiographic-monitoring-for-the-detection-of-high-degree-atrio-ventricular-block-in-patients-with-new-onset-persistent-left-bundle-branch-block-after-transcatheter-aortic-valve-implantation-the-mare-study-100220916","NCT02153307","Ambulatory Electrocardiographic Monitoring for the Detection of High-Degree Atrio-Ventricular Block in Patients With New-onset PeRsistent LEft Bundle Branch Block After Transcatheter Aortic Valve Implantation. The \"MARE\" Study","MARE","Inclusion Criteria:\n\n-Patients undergoing TAVI with either balloon or self-expandable valves who develop new-onset LBBB persistent at hospital discharge, at least 3 days after the procedure\n\nExclusion Criteria:\n\n* Failure to provide informed consent\n* Baseline pacemaker\u002Fdefibrillator or pacemaker\u002Fdefibrillator implanted during the hospitalization period following the TAVI procedure\n* Pre-existing complete LBBB\n* Patients with a life-expectancy of less than 2 years",{"count":59,"type":22},80,"INTERVENTIONAL",[62],"NA","The purpose of this study is to determine the incidence and predictors of high degree or complete atrioventricular block (AVB) (paroxysmal or persistent) in patients with new-onset persistent left bundle branch block (NOP-LBBB) following transcatheter aortic valve implantation (TAVI) and to evaluate the usefulness of the Reveal LINQ® insertable Cardiac Monitor (ICM) (Medtronic, Inc., Minneapolis, USA) for the detection of significant arrhythmias in patients with NOP-LBBB following TAVI.",[65,27],"Aortic Valve Disease","2026-03-23",{"date":68,"type":42},"2026-03-24",{"date":70,"type":4},"2014-01",{"date":72,"type":22},"2026-07",{"name":48,"class":49},""]