[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Centre for Eye and Vision Research\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":72},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,46],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":28,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":34,"lastUpdatePostDateStruct":35,"startDateStruct":38,"completionDateStruct":40,"leadSponsor":42,"locationsCount":45},"100509410","direct-discrimination-of-quantum-states-by-the-human-eye-100509410",false,"NCT05913063","Direct Discrimination of Quantum States by the Human Eye","Direct Discrimination of Quantum States by the Human Eye With Macular Degeneration","Inclusion Criteria:\n\n* Participants who are clinically diagnosed with a vision disease affecting their macula\n* Older adults who are matched for age.\n* Participants who are clinically diagnosed with glaucoma\n* Participants who have normal vision.\n* One aged-matched control with normal vision will be recruited for each of the diagnosed groups (born in the same year).\n\nExclusion Criteria:\n\n* Participants with any additional eye diagnosis or condition",true,"ALL","18 Years",{"count":20,"type":21},50,"ESTIMATED","INTERVENTIONAL",[24],"NA","Age-related macular degeneration (AMD), is a debilitating eye disease that causes a loss of central vision. The prevalence of AMD increases exponentially with age and causes a significant impact through both medical expenses and the social and economic costs associated with vision loss. AMD is the global leading cause of blindness among people over the age of 60. Detection of this eye disease at early stages coupled with prompt treatment can prevent vision loss; however, modern diagnosis methods are ineffective at diagnosis of AMD before vision loss occurs. While a range of available treatment options has been effective at slowing vision loss due to AMD, no treatment exists which can recover lost vision. The investigators propose to apply tools developed in quantum information science to diagnose AMD before vision has been affected, drastically improving health outcomes for patients with AMD.",[27],"Age-Related Macular Degeneration",[27,29,30,31,32],"Structured Light","Orbital Angular Momentum","Polarization Perception","Retinal Imaging","RECRUITING","2026-03-16",{"date":36,"type":37},"2026-03-18","ACTUAL",{"date":39,"type":37},"2023-06-26",{"date":41,"type":21},"2029-10-01",{"name":43,"class":44},"Centre for Eye and Vision Research","OTHER",1,{"id":47,"slug":48,"hasResults":11,"nctId":49,"briefTitle":50,"officialTitle":51,"acronym":52,"eligibilityCriteria":53,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":54,"enrollmentInfo":55,"targetDuration":4,"studyType":22,"phases":57,"briefSummary":58,"conditions":59,"keywords":61,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":34,"lastUpdatePostDateStruct":66,"startDateStruct":67,"completionDateStruct":69,"leadSponsor":71,"locationsCount":5},"100469605","optical-correction-and-visual-functions-of-adults-with-amblyopia-100469605","NCT05394987","Optical Correction and Visual Functions of Adults With Amblyopia","Spectacle Correction for the Treatment of Amblyopia","SPECTRA","Inclusion Criteria:\n\n* 18-39 (inclusive) years of age\n* Anisometropic amblyopia (difference of ≥0.50D spherical equivalent or ≥1.50D astigmatism between eyes) or mixed mechanism amblyopia (strabismus and anisometropia)\n* Best corrected visual acuity (BCVA) in the amblyopic eye of 0.3 logMAR to 1.0 logMAR (inclusive)\n* BCVA in the non-amblyopic eye of 0.1 logMAR or better, and an interocular VA difference of 2 logMAR lines or more\n* Difference of 1.00D or more between current refractive correction and study prescription\n* Good general health\n\nExclusion Criteria:\n\n* Other pathological ocular anomalies known to cause reduced visual acuity\n* Presbyopia (based on amplitude of accommodation)\n* Inability to tolerate prescribed refractive correction in spectacles (e.g., due to aniseikonia)\n* Contraindication to cycloplegic eye drops\n* Currently under amblyopia treatment\u002Ftherapy\n* Inability to comprehend test instructions and\u002For provide consent\n* Eccentric fixation\n* \\>-6.00DS of myopia in either eye with spectacles\n* Bilateral amblyopia\n* Presence of amblyopia that is not due to strabismus and\u002For anisometropia\n* Presence of (current or previous) psychiatric, visual, or neurological disorders","39 Years",{"count":56,"type":21},36,[24],"Amblyopia is a developmental anomaly resulting from abnormal visual experiences in early life. Amblyopia causes reduced visual acuity in the absence of a pathology. Adult sensory systems are believed to be structurally invariant beyond early, critical periods of development. However, recent evidence suggest that visual functions in adults with amblyopia can be improved with optical correction alone. This study aims to investigate whether improvements in best corrected visual acuity and other visual functions can result following appropriate optical correction in adults with amblyopia. Functional measures relating to vision, binocular vision, and eye movements will be used to assess the efficacy of refractive correction for improving vision. This study will help us better understand the improvements in visual functions following optical correction, as well as the mechanisms underlying neuroplasticity in adults with amblyopia.",[60],"Amblyopia",[60,62,63,64,65],"Binocular vision","Suppression","Plasticity","Optical correction",{"date":36,"type":37},{"date":68,"type":37},"2022-06-13",{"date":70,"type":21},"2027-05-31",{"name":43,"class":44},""]