[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Centro Universitario La Salle\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":94},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,46,72],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":29,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":34,"lastUpdatePostDateStruct":35,"startDateStruct":38,"completionDateStruct":40,"leadSponsor":42,"locationsCount":45},"100625849","sex-differences-in-exercise-induced-hypoalgesia-100625849",false,"NCT07427979","Sex Differences in Exercise-Induced Hypoalgesia","Sex Differences in Exercise-Induced Hypoalgesia Following Aerobic Exercise Using a Lower-Limb Cycle Ergometer: A Quasi-Experimental Study","Inclusion Criteria:\n\n* Healthy male and female adults\n* Age between 18 and 65 years\n* Able to perform moderate-to-vigorous aerobic exercise\n* Able to understand study procedures\n* Cleared for exercise participation using the Physical Activity Readiness Questionnaire (PAR-Q).\n\nExclusion Criteria:\n\n* Cardiovascular, respiratory, neurological, or metabolic diseases contraindicating exercise\n* Current musculoskeletal pain or injury\n* Analgesic medication use within 24 hours prior to testing\n* Vigorous exercise within 24 hours prior to testing\n* Any contraindication to aerobic exercise",true,"ALL","18 Years","65 Years",{"count":21,"type":22},30,"ESTIMATED","INTERVENTIONAL",[25],"NA","Exercise-induced hypoalgesia (EIH) refers to the reduction in pain sensitivity following acute exercise. Although aerobic exercise has been shown to induce hypoalgesia in healthy individuals, it remains unclear whether the magnitude of this response differs between men and women.\n\nThis quasi-experimental study aims to evaluate sex differences in pressure pain thresholds following a standardized aerobic exercise protocol using a lower-limb cycle ergometer. Pressure pain thresholds will be assessed before exercise, immediately after exercise, and 30 minutes after exercise in healthy adults aged 18 to 65 years.\n\nThe findings of this study may contribute to improving individualized exercise prescription strategies based on sex differences in pain modulation.",[28],"Healthy Adult",[30,31,32],"Exercise-Induced Hypoalgesia","Sex differences","Aerobic exercise","NOT_YET_RECRUITING","2026-03-16",{"date":36,"type":37},"2026-03-18","ACTUAL",{"date":39,"type":22},"2026-03-15",{"date":41,"type":22},"2026-07-15",{"name":43,"class":44},"Centro Universitario La Salle","OTHER",1,{"id":47,"slug":48,"hasResults":11,"nctId":49,"briefTitle":50,"officialTitle":51,"acronym":4,"eligibilityCriteria":52,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":53,"enrollmentInfo":54,"targetDuration":4,"studyType":23,"phases":56,"briefSummary":57,"conditions":58,"keywords":4,"overallStatus":63,"whyStopped":4,"lastUpdateSubmitDate":64,"lastUpdatePostDateStruct":65,"startDateStruct":67,"completionDateStruct":69,"leadSponsor":71,"locationsCount":45},"100574915","exercise-induced-hypoalgesia-differences-between-upper-and-lower-limbs-resistance-training-interventions-100574915","NCT06765486","Exercise-Induced Hypoalgesia Differences Between Upper and Lower Limbs Resistance Training Interventions","Exercise-Induced Hypoalgesia Differences at Proximal and Distal Regions After Applying a Lower Limb Resistance Training or an Upper Limb Resistance Training Protocol: A Randomized Controlled Trial in Healthy Participants","Inclusion Criteria:\n\n* Asymptomatic subjects aged between 18 and 64 years.\n\nExclusion Criteria:\n\n* Cardiovascular, respiratory, metabolic, neurological, or osteomuscular signs or pathologies.\n* History of epilepsy.\n* Pregnant.\n* Participants who present any type of pain on the day of the measurements or who have frequently suffered pain during the previous 12 weeks.","64 Years",{"count":55,"type":22},90,[25],"This randomized controlled trial with healthy subjects aims to compare exercise-induced hypoalgesia among three groups: one utilizing a lower limb resistance training intervention, another using an upper limb resistance training, and a control group. The exercise protocol involves 3 sets of 5 repetitions of resistance exercises (brachial biceps curl and leg extensions). Exercise-induced hypoalgesia will be assessed by measuring pressure pain thresholds in the thigh and elbow, comparing exercise interventions with the control group. Additionally, a secondary objective is to compare the lower limb and upper limb resistance training groups in terms of their effects on pressure pain thresholds in the thigh and elbow. Thus, the study anticipates observing differences in local and distal hypoalgesia based on the trained region.",[59,60,61,62],"Local Hypoalgesia","Distal Hypoalgesia","Resistance Training","Pressure Pain Thresholds","RECRUITING","2025-02-25",{"date":66,"type":37},"2025-02-26",{"date":68,"type":37},"2025-02-15",{"date":70,"type":22},"2025-06-01",{"name":43,"class":44},{"id":73,"slug":74,"hasResults":11,"nctId":75,"briefTitle":76,"officialTitle":77,"acronym":4,"eligibilityCriteria":78,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":53,"enrollmentInfo":79,"targetDuration":4,"studyType":23,"phases":80,"briefSummary":82,"conditions":83,"keywords":85,"overallStatus":63,"whyStopped":4,"lastUpdateSubmitDate":64,"lastUpdatePostDateStruct":87,"startDateStruct":89,"completionDateStruct":91,"leadSponsor":93,"locationsCount":45},"100537850","phase-1-comparative-exercise-induced-hypoalgesia-in-upper-and-lower-limbs-a-randomized-controlled-trial-in-healthy-individuals-100537850","NCT06283186","Comparative Exercise-Induced Hypoalgesia in Upper and Lower Limbs: A Randomized Controlled Trial in Healthy Individuals","Differences in Exercise-Induced Hypoalgesia at Local and Distal Levels Using Lower and Upper Limb Cycle Ergometer Protocols: A Randomized Controlled Trial in Healthy Participants","Inclusion Criteria:\n\n* Asymptomatic subjects aged between 18 and 64 years.\n\nExclusion Criteria:\n\n* Cardiovascular, respiratory, metabolic, neurological, or osteomuscular signs or pathologies.\n* History of epilepsy.\n* Pregnant\n* Pharmacological treatment.\n* Participants who present any type of pain on the day of the measurements or who have frequently suffered pain during the previous 12 weeks.",{"count":55,"type":22},[81],"PHASE1","This randomized controlled trial with healthy subjects aims to compare exercise-induced hypoalgesia among three groups: one utilizing a lower limb cycle ergometer, another using an upper limb cycle ergometer, and a control group. The exercise protocol involves 30 minutes of aerobic activity at 70-80% of the heart rate reserve. Exercise-induced hypoalgesia will be assessed by measuring pressure pain thresholds in the thigh and elbow. Additionally, a secondary objective is to compare the lower limb and upper limb cycle ergometer groups in terms of their effects on pressure pain thresholds in the thigh and elbow. Thus, the study anticipates observing differences in local and distal hypoalgesia based on the trained region.",[84],"Healthy Subjects",[59,60,86,62],"Aerobic Exercise",{"date":88,"type":37},"2025-02-27",{"date":90,"type":37},"2024-04-23",{"date":92,"type":22},"2025-07-31",{"name":43,"class":44},""]