[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Changhua Christian Hospital\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":154},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,5,0,[8,49,82,109,132],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":29,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":37,"lastUpdatePostDateStruct":38,"startDateStruct":41,"completionDateStruct":43,"leadSponsor":45,"locationsCount":48},"100634803","diaphragmatic-training-on-gerd-100634803",false,"NCT07544433","Diaphragmatic Training on GERD","Diaphragmatic Training for Gastroesophageal Reflux Disease: A Randomized Controlled Trial Comparing the Effects of Diaphragmatic Breathing Exercise and Incentive Spirometry Training on Esophageal Dynamics and Quality of Life","GERD","Include Criteria:\n\n* Age between 20 and 80 years.2. A confirmed diagnosis of gastroesophageal reflux disease (GERD), defined by at least one of the following criteria\n* Endoscopic examination within the past 3 months demonstrating Los Angeles (LA) grade A reflux esophagitis with regular use of acid-suppressive medication (e.g., proton pump inhibitors) for more than 2 months.\n* 24-hour esophageal pH monitoring showing acid exposure time (AET) \\> 6%.\n* Endoscopic examination within the past 3 months demonstrating LA grade B or higher reflux esophagitis.\n* Willingness and ability to participate in the intervention program, including adherence to training protocols, scheduled follow-up visits, and completion of all required assessments during the study period.\n\nExclusion Criteria\n\n* Pregnant or breastfeeding women.\n* History of anti-reflux surgery or other upper gastrointestinal surgical procedures related to GERD.\n* Presence of significant cardiopulmonary disease or chronic respiratory disease that may compromise the safety or feasibility of performing breathing training.\n* Inability to comply with the study protocol, including participation in training procedures and scheduled follow-up visits, due to conditions such as cognitive impairment, physical limitations, or inability to attend regular visits.","ALL","20 Years","80 Years",{"count":21,"type":22},42,"ESTIMATED","INTERVENTIONAL",[25],"NA","he goal of this clinical trial is to evaluate the effects of diaphragm-oriented breathing training on patients with gastroesophageal reflux disease (GERD). This study will compare two non-invasive respiratory interventions-diaphragmatic breathing exercise (DBE) and volume-oriented incentive spirometry (VIS)-in terms of their impact on esophageal function and health-related quality of life.The main questions it aims to answer are:Does DBE or VIS improve GERD symptoms as measured by the GERD Questionnaire (GERDQ)?Do these interventions reduce esophageal acid exposure time and the number of reflux episodes?Do these interventions improve lower esophageal sphincter (LES) pressure and esophageal motility?Do these interventions improve GERD-related quality of life as measured by the GERD-HRQL questionnaire?Researchers will compare three groups: DBE, VIS, and a control group receiving standard care, to determine whether diaphragm-oriented breathing training provides additional benefits over usual management.Participants will:Be randomly assigned to one of three groups (DBE, VIS, or control)Perform the assigned intervention for 6 weeksUndergo baseline and post-intervention assessments, including symptom questionnaires and esophageal function testing Record symptoms and adherence in a daily diary",[15,28],"Diaphragmatic Training",[15,30,31,32,33,34,35],"incentive spirometry","esophageal dynamics","quality of life","Diaphragmatic training","diaphragmatic breathing exercise","incentive spirometry training","RECRUITING","2026-04-15",{"date":39,"type":40},"2026-04-22","ACTUAL",{"date":42,"type":40},"2026-03-04",{"date":44,"type":22},"2028-09-30",{"name":46,"class":47},"Changhua Christian Hospital","OTHER",1,{"id":50,"slug":51,"hasResults":11,"nctId":52,"briefTitle":53,"officialTitle":54,"acronym":4,"eligibilityCriteria":55,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":56,"targetDuration":4,"studyType":23,"phases":58,"briefSummary":59,"conditions":60,"keywords":65,"overallStatus":73,"whyStopped":4,"lastUpdateSubmitDate":74,"lastUpdatePostDateStruct":75,"startDateStruct":77,"completionDateStruct":79,"leadSponsor":81,"locationsCount":4},"100606722","effect-of-breathing-training-on-symptoms-of-gastroesophageal-reflux-disease-100606722","NCT07179250","Effect of Breathing Training on Symptoms of Gastroesophageal Reflux Disease","Effect of Breathing Training on Symptoms of Gastroesophageal Reflux Disease: A Parallel Randomized Controlled Trial","Inclusion Criteria:\n\n* Adults aged 20 to 80 years\n* Endoscopic finding of reflux esophagitis (LA grade A) with proton pump inhibitor (PPI) use \\> 2 months, or 24-hour pH monitoring showing acid exposure time (AET) \\> 6%, or endoscopic diagnosis of reflux esophagitis LA grade B or higher\n* Willingness to comply with the full training and follow-up protocol\n\nExclusion Criteria:\n\n* Pregnant or breastfeeding women\n* History of anti-reflux surgery\n* Severe cardiopulmonary dysfunction or respiratory disease\n* Inability to perform the training exercises or attend follow-up visits",{"count":57,"type":22},51,[25],"The goal of this clinical trial is to evaluate whether two types of breathing training can improve symptoms of gastroesophageal reflux disease (GERD) in adults.\n\nThe main research questions are:\n\n* Do volume-oriented incentive spirometry (VIS) or diaphragmatic breathing exercise (DBE) improve GERD symptoms compared with usual care?\n* Do these breathing exercises reduce the symptoms of GERD?\n* Does volume-oriented incentive spirometry (VIS) produce greater improvement in GERD symptoms compared with DBE?\n* Do these exercises increase the strength of the lower esophageal sphincter (LES)?\n\nResearchers will compare VIS training, DBE training, and usual care to determine whether breathing training can serve as a safe and effective non-pharmacological treatment option for GERD.\n\nParticipants will:\n\n* Be randomly assigned to VIS training, DBE training, or usual care\n* Perform their assigned breathing training (if in the intervention group) twice daily for 6 weeks\n* Attend study visits at baseline and at week 7 for questionnaires and esophageal function tests\n* Keep a diary of their symptoms and breathing practice",[61,62,63,64],"Incentive Spirometer","Diaphragmatic Breathing","Gastroesophageal Reflux Disease (GERD)","Breath Exercise",[15,66,67,62,68,61,69,70,71,72],"Gastroesophageal Reflux Disease","Acid Reflux","Breathing Training","Volume-Oriented Incentive Spirometry","GERDQ","Gastroesophageal Reflux Disease Questionnaire","breath exercise","NOT_YET_RECRUITING","2025-09-23",{"date":76,"type":40},"2025-09-26",{"date":78,"type":22},"2025-09",{"date":80,"type":22},"2026-05",{"name":46,"class":47},{"id":83,"slug":84,"hasResults":11,"nctId":85,"briefTitle":86,"officialTitle":87,"acronym":4,"eligibilityCriteria":88,"healthyVolunteers":11,"sex":17,"minAge":89,"maxAge":90,"enrollmentInfo":91,"targetDuration":4,"studyType":23,"phases":93,"briefSummary":94,"conditions":95,"keywords":98,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":101,"lastUpdatePostDateStruct":102,"startDateStruct":104,"completionDateStruct":106,"leadSponsor":108,"locationsCount":48},"100596035","effects-on-subacute-stroke-with-robotic-assistive-gait-training-100596035","NCT07040215","Effects on Subacute Stroke With Robotic Assistive Gait Training","The Effectiveness of Subacute Stroke Patients Receiving Robotic Assisted Gait Training","Inclusion Criteria:\n\n* Diagnosed with stroke (ischemic or hemorrhagic) confirmed by medical imaging.\n* Subacute phase of stroke (onset within 1 to 3 months).\n* Moderate to good standing balance ability.\n* Sufficient cognitive ability to understand the study and follow instructions.\n* Able to participate in rehabilitation training during the study period.\n\nExclusion Criteria:\n\n* Body weight over 90 kg.\n* Presence of other neurological disorders.\n* Severe cardiovascular disease or other health conditions affecting mobility.\n* Significant lower limb pain, joint contracture, or spasticity (Modified Ashworth Scale score \\> 3) that impairs walking.\n* Diagnosed with cardiopulmonary disease that contraindicates exercise training.\n* Cognitive impairment that prevents understanding of training instructions or completion of questionnaires.\n* Inability to complete the rehabilitation training protocol.","45 Years","70 Years",{"count":92,"type":22},40,[25],"The goal of this randomized controlled trial is to learn about the effects of Robotic Assisted Gait Training (RAGT) combined with traditional physical therapy in subacute stroke patients. The main question it aims to answer is:\n\n\\- Does RAGT combined with traditional physical therapy improve gait and functional performance in subacute stroke patients compared to traditional physical therapy alone? Participants who are subacute stroke patients will be randomly assigned to receive either both RAGT and traditional physical therapy or only traditional physical therapy. Their gait and functional performance will be assessed during the study period.",[96,97],"Stroke","Stroke Gait Rehabilitation",[99,100],"physiotherapy","Robotic Assistive Gait Training","2025-06-26",{"date":103,"type":40},"2025-06-27",{"date":105,"type":22},"2025-07-01",{"date":107,"type":22},"2026-04-30",{"name":46,"class":47},{"id":110,"slug":111,"hasResults":11,"nctId":112,"briefTitle":113,"officialTitle":114,"acronym":4,"eligibilityCriteria":115,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":116,"targetDuration":4,"studyType":23,"phases":118,"briefSummary":119,"conditions":120,"keywords":122,"overallStatus":73,"whyStopped":4,"lastUpdateSubmitDate":124,"lastUpdatePostDateStruct":125,"startDateStruct":127,"completionDateStruct":129,"leadSponsor":131,"locationsCount":4},"100590700","explore-the-effect-of-bitter-melon-peptides-on-glycemic-control-and-metabolic-indicators-in-diabetic-patients-100590700","NCT06970834","Explore the Effect of Bitter Melon Peptides on Glycemic Control and Metabolic Indicators in Diabetic Patients","Using Continuous Glucose Monitoring Tools to Explore the Effect of Bitter Melon Peptides on Glycemic Control and Metabolic Indicators in Diabetic Patients","Inclusion Criteria:Participants were diagnosed with type 2 DM based on criteria recommended by the American Diabetes Association and required to have fasting plasma glucose of ≥126 mg\u002Fdl or an HbA1c of\n\n≥ 6.5%, as measured on two separate occasions\n\nExclusion Criteria:cancer, active liver disease, current pregnancy , acute illness and autoimmune thyroid disease.",{"count":117,"type":22},160,[25],"The goal of this clinical trial is to learn the potential of bitter melon peptides in stabilizing blood glucose in diabetic adults. It will also learn about the effects of bitter melon peptides on metabolic parameters. The main questions it aims to answer are:\n\n* the regulatory effects of bitter melon peptides on glycemic variability\n* impact on glycemic and metabolic indicators Researchers will compare bitter melon peptides to a placebo (a look-alike capsule that contains Microcrystalline Cellulose) to see if bitter melon peptides works to stabilizing blood glucose.\n\nParticipants will:\n\n* Take bitter melon peptides or a placebo every day for 12 weeks\n* Visit the clinic on day 0, day 7, day 28 and day 84 for checkups and tests\n* Glucose levels were monitored continuously by CGMs in the first 7 days and fasting blood samples were drawn at first visit (day0), third visit (day 28) and fourth visits (day 84)",[121],"Diabetes",[123],"bitter melon peptides","2025-05-06",{"date":126,"type":40},"2025-05-14",{"date":128,"type":22},"2025-05-27",{"date":130,"type":22},"2026-03-26",{"name":46,"class":47},{"id":133,"slug":134,"hasResults":11,"nctId":135,"briefTitle":136,"officialTitle":137,"acronym":4,"eligibilityCriteria":138,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":139,"targetDuration":4,"studyType":23,"phases":141,"briefSummary":143,"conditions":144,"keywords":4,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":146,"lastUpdatePostDateStruct":147,"startDateStruct":149,"completionDateStruct":151,"leadSponsor":153,"locationsCount":48},"100488303","phase-2-evaluation-of-the-curative-effect-of-ru-yi-jin-huang-saan-100488303","NCT05638360","Evaluation of the Curative Effect of Ru-Yi-Jin-Huang-Saan","Evaluation of the Efficacy of Ru-Yi-Jin-Huang-Saan on Colles' Fracture ---a Randomized, Double-blind, Placebo-controlled Trial","Inclusion Criteria:\n\n1. People who are over 20 years old and have no lack of mental ability can understand the content of the experiment and are willing to participate in it.\n2. Patients with Colles' fracture receive surgical fixation(ORIF).\n\nExclusion Criteria:\n\n1. People are unable to cooperate with experiments and fill out questionnaires.\n2. Patients have wounds on the back of their wrists.\n3. Patients are allergic to traditional Chinese medicine for external applications or have used other traditional Chinese medicine for external applications.\n4. Patients have cancer, stroke, and systemic diseases such as severe anemia, thyroid disease, uncontrolled diabetes, etc.\n5. Pregnant woman.",{"count":140,"type":22},100,[142],"PHASE2","The purpose of this study is to assess the efficacy and safety of Ru-Yi-Jin-Huang-Saan for the treatment of Colles' fracture.",[145],"Colles' Fracture","2025-03-16",{"date":148,"type":40},"2025-03-19",{"date":150,"type":40},"2023-05-01",{"date":152,"type":22},"2025-09-30",{"name":46,"class":47},""]