[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Children's Healthcare of Atlanta\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":73},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,46],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":29,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":34,"lastUpdatePostDateStruct":35,"startDateStruct":38,"completionDateStruct":40,"leadSponsor":42,"locationsCount":45},"100392441","bfrt-in-adolescents-after-acl-reconstruction-100392441",false,"NCT04390035","BFRT in Adolescents After ACL Reconstruction","Blood Flow Restriction Training in the Adolescent Patient: Effects on Muscle Strength and Overall Function Following Anterior Cruciate Ligament Reconstruction Surgery","Inclusion Criteria:\n\n1. Adolescent male and female patients, age 12-18\n2. Skeletally mature at time of diagnosis, with closed growth plates, as determined via standard clinic x-ray imaging (this specification automatically excludes pre-pubescent children.\n3. Underwent transphyseal ACLR with quadriceps tendon autograft with one of three sports orthopedic surgeons at CHOA\n4. Completed pre-surgery strength assessment of bilateral quadriceps, hamstrings, hip abductor and hip adductor musculature.\n5. English-speaking adolescents and parents of all races and ethnicities (after preliminary data is achieved, PI will coordinate a larger multi-center study that will include all non-English speaking participants.\n\nExclusion Criteria:\n\n1. Skeletally immature patients with open growth plates, as determined via standard clinic x-ray imaging\n2. Concomitant procedures performed during ACLR which require weight-bearing restrictions (i.e. meniscus repair, microfracture, multi-ligament knee reconstruction)\n3. History of previous knee surgery\n4. History of cardiovascular disease (e.g. coronary artery disease, unstable hypertension, vascular endothelial dysfunction, peripheral artery disease, varicose veins)\n5. ICD-10 diagnosis of bleeding disorder (e.g. hemophilia or blood clotting disorder) or use of anticoagulants or other medications that may affect blood clotting\n6. Inability to adhere to treatment protocol (as described in study procedures, BFR-LLT treatment requirements)\n7. Any adverse events intra-operatively or post-operatively that lead to delay in care, including infection\n8. Failure to adhere to attendance requirements as detailed below:\n\n   * Attend first PT visit (PTV) within 5 days post-surgery\n   * Attend a minimum of 20 total PTVs during weeks 1-16 post-surgery",true,"ALL","12 Years","18 Years",{"count":21,"type":22},120,"ESTIMATED","INTERVENTIONAL",[25],"NA","This is an interventional study that will examine effects of blood flow restriction training (BFRT) in adolescents aged 12-18 after anterior cruciate ligament reconstruction surgery (ACLR). The study aims to identify the effect of BFRT on quadriceps muscle strength and the patient's quality of life, and the overall tolerability of BFRT will be examined. Eight physical therapists at four sports medicine physical therapy (PT) sites will oversee all post-operative PT sessions. Subjects allocated to the BFR group will undergo BFRT, while control group will undergo standard-of-care ACLR rehabilitation, 2 days per week for 16 weeks. Measurements of strength, quality of life, and overall function will be completed at regular intervals.",[28],"Anterior Cruciate Ligament Rupture",[30,31,32],"Adolescents","Blood Flow Restriction Training","Patient-reported Outcomes","RECRUITING","2021-07-27",{"date":36,"type":37},"2021-08-02","ACTUAL",{"date":39,"type":37},"2020-09-23",{"date":41,"type":22},"2023-04",{"name":43,"class":44},"Children's Healthcare of Atlanta","OTHER",1,{"id":47,"slug":48,"hasResults":11,"nctId":49,"briefTitle":50,"officialTitle":51,"acronym":4,"eligibilityCriteria":52,"healthyVolunteers":16,"sex":17,"minAge":53,"maxAge":19,"enrollmentInfo":54,"targetDuration":4,"studyType":23,"phases":56,"briefSummary":58,"conditions":59,"keywords":62,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":65,"lastUpdatePostDateStruct":66,"startDateStruct":68,"completionDateStruct":70,"leadSponsor":72,"locationsCount":45},"100333721","phase-4-gabapentin-premedication-to-reduce-postoperative-pain-for-pediatric-tonsillectomy-100333721","NCT03625011","Gabapentin Premedication to Reduce Postoperative Pain for Pediatric Tonsillectomy","Gabapentin Premedication to Reduce Postoperative Pain for Pediatric Tonsillectomy\u002FAdenoidectomy: Randomized Control Trial","Inclusion Criteria:\n\n* participants age 3-18 years\n* ASA class 1 or 2\n* elective Tonsillectomy\u002FAdenoidectomy\n* outpatient setting.\n\nExclusion Criteria:\n\n* BMI \\>40kg\u002Fm2\n* history of renal insufficiency, chronic pain\n* allergy to gabapentin\n* history of developmental delay","3 Years",{"count":55,"type":22},50,[57],"PHASE4","The purpose of this pilot study: 1) to examine the use of gabapentin in reducing pain in the first 48 hours postoperatively including the total amount of narcotics mg\u002Fkg given 2) to record the time to first analgesic postoperatively and 3) to compare Wong Baker and the 0-10 numeric pain distress scale scores at 12, 24 and 48 hours postoperatively. We hypothesize one 15mg\u002Fkg (up to 600mg) dose of gabapentin will decrease mean narcotic amounts in mg\u002Fkg compared to participants who do not receive preoperative gabapentin and will demonstrate a decreased mean time to first analgesic as well as to lower mean pain scores for each age group at 12, 24 and 48 hours.",[60,61],"Tonsillitis","Tonsillectomy",[63,64],"Pain Relief","Non-Narcotic Pain relief","2019-07-23",{"date":67,"type":37},"2019-07-24",{"date":69,"type":37},"2018-07-31",{"date":71,"type":22},"2019-12-31",{"name":43,"class":44},""]