[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Chung-Ang University Gwangmyeong Hospital\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":81},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,52],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":29,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":40,"lastUpdatePostDateStruct":41,"startDateStruct":44,"completionDateStruct":46,"leadSponsor":48,"locationsCount":51},"100644453","phase-4-remimazolam-flumazenil-versus-sevoflurane-for-hysteroscopic-day-surgery-100644453",false,"NCT07663877","Remimazolam-Flumazenil Versus Sevoflurane for Hysteroscopic Day Surgery","Remimazolam With Planned Flumazenil Reversal Versus Sevoflurane-based Balanced Anesthesia for Hysteroscopic Day Surgery: A Randomized Controlled Trial","Inclusion Criteria:\n\n* Female patients aged 20 years or older.\n* Scheduled to undergo ambulatory hysteroscopic surgery under general anesthesia.\n* Able to provide written informed consent.\n* American Society of Anesthesiologists (ASA) physical status I-III.\n\nExclusion Criteria:\n\n* Known hypersensitivity to benzodiazepines, remimazolam, or flumazenil.\n* Chronic use of benzodiazepines or opioids.\n* Severe hepatic dysfunction (Child-Pugh class B or C).\n* Severe renal dysfunction (estimated glomerular filtration rate \\\u003C30 mL\u002Fmin\u002F1.73 m²).\n* Epilepsy or other significant neurologic disorders.\n* Pregnancy or breastfeeding.\n* Body mass index (BMI) ≥35 kg\u002Fm².\n* Severe obstructive sleep apnea.\n* Uncontrolled serious systemic disease that may preclude ambulatory surgery.\n* Refusal or inability to provide informed consent.","FEMALE","20 Years",{"count":19,"type":20},124,"ESTIMATED","INTERVENTIONAL",[23],"PHASE4","This prospective, single-center, randomized controlled trial aims to compare remimazolam anesthesia with planned flumazenil reversal and sevoflurane-based balanced anesthesia in adult women undergoing ambulatory hysteroscopic surgery.\n\nParticipants will be randomly assigned in a 1:1 ratio to receive either remimazolam for induction and maintenance followed by flumazenil reversal or propofol induction followed by sevoflurane-based balanced anesthesia. The primary outcome is anesthesia-controlled time, defined as the sum of induction time and emergence time. Secondary outcomes include recovery profiles, postoperative symptoms, quality of recovery, hemodynamic stability, and the incidence of re-sedation. The study will evaluate whether a remimazolam-flumazenil strategy can improve operating room efficiency while maintaining recovery quality and safety comparable to conventional sevoflurane-based anesthesia in the ambulatory surgery setting.",[26,27,28],"Hysteroscopy","Ambulatory Surgery","General Anesthesia",[30,31,32,33,34,35,36,37,38],"remimazolam","flumazenil","sevoflurane","ambulatory surgery","day surgery","hysteroscopy","general anesthesia","recovery profile","anesthesia controlled time","NOT_YET_RECRUITING","2026-06-17",{"date":42,"type":43},"2026-06-23","ACTUAL",{"date":45,"type":20},"2026-06",{"date":47,"type":20},"2028-06",{"name":49,"class":50},"Chung-Ang University Gwangmyeong Hospital","OTHER",1,{"id":53,"slug":54,"hasResults":11,"nctId":55,"briefTitle":56,"officialTitle":57,"acronym":4,"eligibilityCriteria":58,"healthyVolunteers":11,"sex":59,"minAge":60,"maxAge":4,"enrollmentInfo":61,"targetDuration":4,"studyType":21,"phases":63,"briefSummary":64,"conditions":65,"keywords":70,"overallStatus":72,"whyStopped":4,"lastUpdateSubmitDate":73,"lastUpdatePostDateStruct":74,"startDateStruct":76,"completionDateStruct":78,"leadSponsor":80,"locationsCount":51},"100555062","phase-4-comparison-of-remimazolam-and-propofol-for-recovery-of-ambulatory-upper-airway-surgery-100555062","NCT06507202","Comparison of Remimazolam and Propofol for Recovery of Ambulatory Upper Airway Surgery","Comparison of Remimazolam Versus Propofol-based General Anesthesia on Postoperative Quality of Recovery in Patients Undergoing Ambulatory Upper Airway Surgery: a Randomized Controlled Trial","Inclusion Criteria:\n\n* Adult patients (age 19 or older) undergoing ambulatory upper respiratory tract (nasal cavity, oral cavity, pharynx, larynx) surgery under general anesthesia\n* American Society of Anesthesiologists physical class classification I, II, and III\n\nExclusion Criteria:\n\n* Patients who refused to participate in the study\n* Pregnant patients\n* Patients with a history of hypersensitivity to drugs or additives used during surgery\n* Patients with acute narrow-angle glaucoma\n* Alcohol or drug dependent patients\n* Patients with Child-Pugh class C liver dysfunction","ALL","19 Years",{"count":62,"type":20},116,[23],"The purpose of this study is to compare the effects of remimazolam and propofol on postoperative recovery time, complications, and safety in patients undergoing ambulatory upper airway surgery under general anesthesia.",[66,67,68,69],"Laryngeal Disease","Pharyngeal Diseases","Oral Cavity Disease","Nasal Disease",[30,71,33],"upper airway surgery","RECRUITING","2024-07-11",{"date":75,"type":43},"2024-07-18",{"date":77,"type":43},"2024-01-22",{"date":79,"type":20},"2025-03-22",{"name":49,"class":50},""]