[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Clinique Paris-Bercy\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":100},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,48,75],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":23,"conditions":24,"keywords":26,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":36,"lastUpdatePostDateStruct":37,"startDateStruct":40,"completionDateStruct":42,"leadSponsor":44,"locationsCount":47},"100625573","colo-predict-digital-training-and-optical-diagnosis-of-colorectal-polyps-100625573",false,"NCT07424391","COLO-PREDICT: Digital Training and Optical Diagnosis of Colorectal Polyps","Impact of a Digital Training Program (Colo-ID) on Optical Histologic Prediction and Management of Colorectal Polyps: A Prospective Study","COLO-PREDICT","Inclusion Criteria:\n\n* Adults aged ≥18 years\n* Patients undergoing colonoscopy in routine clinical practice at the participating center\n* At least one colorectal polyp detected during colonoscopy\n* Optical histology prediction recorded during the procedure\n* Histopathological analysis available for resected polyps (reference standard)\n\nExclusion Criteria:\n\n* Patients aged \\\u003C18 years\n* Refusal\u002Fopposition to use of data (if applicable under local regulations)\n* Missing key study data (e.g., no recorded optical prediction or no histopathology result)","ALL","18 Years",{"count":20,"type":21},1500,"ESTIMATED","OBSERVATIONAL","Colorectal cancer prevention relies on high-quality colonoscopy and accurate optical characterization of colorectal polyps. Optical diagnosis may allow optimization of management strategies such as resect-and-discard for diminutive polyps, potentially improving efficiency in routine practice.\n\nCOLO-PREDICT is a prospective, single-center, observational study designed to evaluate the impact of a structured digital training program (Colo-ID, a digital application for colonic polyp characterisation training) on the accuracy of optical histology prediction of colorectal polyps in real-life clinical practice.\n\nAll consecutive adult patients undergoing colonoscopy with at least one detected polyp will be included. Optical prediction of polyp histology will be recorded during the procedure. All polyps will be resected and sent for histopathological analysis according to standard practice. No modification of patient management will occur as part of the study.\n\nThe primary objective is to assess the concordance between optical prediction and histopathology before and after implementation of the digital training program. Secondary objectives include evaluation of prediction performance according to polyp characteristics and assessment of potential implications for clinical practice.",[25],"Colorectal Polyps",[27,28,29,30,31,32,33,34],"Optical diagnosis","Colonoscopy","Histologic prediction","Resect-and-discard strategy","Digital training","Endoscopic imaging","Polyp characterization","Real-world study","RECRUITING","2026-02-20",{"date":38,"type":39},"2026-02-23","ACTUAL",{"date":41,"type":39},"2026-02-09",{"date":43,"type":21},"2026-09",{"name":45,"class":46},"Clinique Paris-Bercy","OTHER",1,{"id":49,"slug":50,"hasResults":11,"nctId":51,"briefTitle":52,"officialTitle":53,"acronym":54,"eligibilityCriteria":55,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":56,"targetDuration":4,"studyType":58,"phases":59,"briefSummary":61,"conditions":62,"keywords":4,"overallStatus":66,"whyStopped":4,"lastUpdateSubmitDate":67,"lastUpdatePostDateStruct":68,"startDateStruct":70,"completionDateStruct":72,"leadSponsor":74,"locationsCount":47},"100620742","study-comparing-the-quality-of-colon-cleanliness-with-prepackaged-lrd-low-residue-diet-vs-guided-pog-100620742","NCT07361575","Study Comparing the Quality of Colon Cleanliness With Prepackaged LRD (Low-residue Diet) vs. Guided (POG).","A Single-blind, Randomized Study Comparing the Quality of Colon Cleanliness With Prepackaged LRD (Low-residue Diet) vs. Guided (POG).","POG","Inclusion Criteria:\n\n* Patient of one of the investigators for total colonoscopy (no prior colonic surgery);\n* Patient aged 18 years or older;\n* Patient classified as ASA 1, ASA 2, or ASA 3;\n* Not participating in any other current clinical trial;\n* Free, informed, and signed consent;\n* Patient affiliated with or a beneficiary of a social security scheme, according to Article L.1124-1 of the French Public Health Code;\n\nExclusion Criteria:\n\n* Patient taking major psychotropic medications;\n* Patient with uncontrolled diabetes;\n* Patient with coagulation abnormalities preventing polypectomy: PT \\\u003C50%, Platelets \\\u003C50,000\u002Fmm³, current effective anticoagulation therapy (clopidogrel, prasugrel, or ticagrelor);\n* Patient referred for removal of a known polyp;\n* Chronic inflammatory bowel disease;\n* Known colonic stenosis;\n* Diverticulitis of less than 6 weeks duration;\n* Pregnant, parturient, or breastfeeding woman;\n* Patient deprived of liberty by administrative or judicial order, or under guardianship or limited legal protection;\n* Patient unable to understand the objectives and constraints of the study.",{"count":57,"type":21},230,"INTERVENTIONAL",[60],"NA","Low-residue diet (LRD) in patient improves the quality of the colon cleanliness and thus the adenoma detection rate (ADR). This is a key criterion in colonoscopy screening for colorectal cancer (CRC). The benefit of an LRD lasting more than 24 hours before colonoscopy has not been demonstrated compared to a 24-hour LRD.\n\nFew studies have evaluated the benefit of a prepackaged 24-hour LRD compared to simply receiving oral and written LRD instructions during a consultation.\n\nThe aim of the study is to evaluate the usefulness of a prepackaged LRD (Colobox®) compared to simple LRD instructions on colon cleanliness (Boston score) in patients examined by endoscopy.",[63,64,65],"Colorectal Cancer Prevention","Colorectal Cancer (Diagnosis)","Colorectal Adenocarcinoma","NOT_YET_RECRUITING","2026-02-13",{"date":69,"type":39},"2026-02-17",{"date":71,"type":21},"2026-01-30",{"date":73,"type":21},"2026-11-30",{"name":45,"class":46},{"id":76,"slug":77,"hasResults":11,"nctId":78,"briefTitle":79,"officialTitle":79,"acronym":4,"eligibilityCriteria":80,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":81,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":83,"conditions":84,"keywords":86,"overallStatus":66,"whyStopped":4,"lastUpdateSubmitDate":92,"lastUpdatePostDateStruct":93,"startDateStruct":95,"completionDateStruct":97,"leadSponsor":99,"locationsCount":47},"100518219","prospective-evaluation-of-subchondroplasty-in-advanced-knee-osteoarthritis-100518219","NCT06027697","Prospective Evaluation of Subchondroplasty in Advanced Knee Osteoarthritis.","Inclusion Criteria:\n\n* Patient 18 years of age or older;\n* Patient with a Body Mass Index ≤35 (BMI=kg\u002Fm2);\n* Patient with Kellgren-Lawrence grade 3-4 Osteoarthritis, as reviewed on MRI and plain radiography;\n* Patient with knee bone marrow lesions confirmed by MRI result at least 3 months before the intervention;\n* Patients with degenerative knee pathology at the prosthetic stage (outdated medical treatments), with a frontal deformity of less than 12°, (and wishing to avoid or delay the prosthetic procedure as much as possible) \u002F goniometry);\n* Patient with unbearable mechanical pain with a walking perimeter limited at 500 m\n* Patient with non-surgical treatment failure (infiltration of Platelet Rich Plasma (PRP), corticoids, acid hyaluronic);\n* Patient who agrees to participate in the study and who signed the informed non-opposition form;\n* Patient physically and mentally willing and able, in the Investigator's opinion at the time of enrolment, to be compliant with the protocol including all follow-up visits, survey completion, weight- bearing restrictions, and post-operative rehabilitation;\n* Patient with social protection.\n\nExclusion Criteria:\n\n* Patient with a Body Mass Index \\> 35 (BMI=kg\u002Fm2);\n* Patient with inflammatory rheumatic pathologies;\n* Patient with frontal deformities (varus, valgus) of more than 12°;\n* Patient with degenerative pathologies at the operative stage but likely to benefit from a conservative intervention (osteotomy), except if the knee is centred;\n* Patient with stiff knees (more than 20° of flexum and\u002For less than 90° of flexion);\n* Patient with painful severe femoro-patellar osteoarthritis;\n* Patient with contraindications for Magnetic Resonance Imaging (MRI);\n* Patient with history of systemic diseases which could contribute to secondary arthropathies (e.g., sickle cell disease, hemochromatosis, or autoimmune disease);\n* Patient with history of cognitive-behavioural disorders that could interact with assessment by self-questionnaire;\n* Patient with local or general infection or suspicion of infection;\n* Patient with severe coagulation disorders;\n* Patient with primary bone tumour in the knee area,\n* Patient with undercurrent serious pathology with life expectance \\\u003C 2 years;\n* Female patient of childbearing age that are known to be pregnant during inclusion visit or wishing to become pregnant before treatment;\n* Patient who has forfeited their freedom by administrative or legal award, or is under guardianship or under limited judicial protection;\n* Patient participating in another interventional clinical trial or testing an experimental drug within 30 days of inclusion in the study;\n* Patients who cannot read or write French",{"count":82,"type":21},55,"The goal of this observational study is to evaluate the technique of subchondroplasty in patients with advanced knee osteoarthritis.\n\nThe main question it aims to answer is:\n\n• Does the subchondroplasty technique with the administration of AccuFill Porous Bone Substitute Material (BSM) is effective in the relief of mechanical pain in patient with knee osteoarthritis ?\n\nParticipants will go under a minimally invasive surgery procedure (subchondroplasty) and fulfil 3 validated questionnaires to assess pain, functional impairments and subjective improvement.\n\nThis study will be conducted for 4 years.",[85],"Knee Osteoarthritis",[87,88,89,90,91],"Knee osteoarthritis","Subchondroplasty","Knee mechanical pain","AccuFill Porous Bone Substitute Material","Minimally invasive surgical procedure","2023-08-31",{"date":94,"type":39},"2023-09-07",{"date":96,"type":21},"2023-12",{"date":98,"type":21},"2028-09",{"name":45,"class":46},""]