[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Clinique Saint Jean, France\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":180},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,7,0,[8,42,66,88,110,135,159],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":4,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":30,"lastUpdatePostDateStruct":31,"startDateStruct":34,"completionDateStruct":36,"leadSponsor":38,"locationsCount":41},"100643249","concordance-for-transthyretin-amyloidosis-between-synovial-biopsy-and-anterior-carpal-ligament-biopsy-100643249",false,"NCT07644325","Concordance for Transthyretin Amyloidosis Between Synovial Biopsy and Anterior Carpal Ligament Biopsy","Assessment of Diagnostic Concordance for Transthyretin Amyloidosis Between Synovial Biopsy and Anterior Carpal Ligament Biopsy in Patients Who Underwent Endoscopic Carpal Tunnel Syndrome Surgery","ATTR2026","Inclusion Criteria:\n\n* Adult patient with Health Insurance\n* Clinical diagnosis + carpal tunnel EMG\n* Validated indication for carpal tunnel surgery\n* Signed informed consent\n* Patient at risk for postoperative complications (bilateral carpal tunnel syndrome, heart failure, atrial fibrillation, elderly patients)\n\nExclusion Criteria:\n\n* Need for open carpal tunnel surgery.\n* Pregnant women\n* Adults under guardianship","ALL","18 Years",{"count":20,"type":21},500,"ESTIMATED","INTERVENTIONAL",[24],"NA","Transthyretin amyloidosis (ATTR) is an underdiagnosed condition that can present early as carpal tunnel syndrome, sometimes preceding cardiac involvement by several years. The recent emergence of new treatments underscores the importance of early diagnosis. Synovial biopsy performed during open carpal tunnel surgery is considered the gold standard for local screening, but it is less accessible, more difficult, and riskier to perform via endoscopy-a minimally invasive surgical technique that is currently the standard at our center and is becoming increasingly widespread.\n\nThe anterior annular ligament of the carpus constitutes an alternative tissue to the synovium, easily accessible via endoscopy, safe, and standardizable.\n\nIn this study, the systematic performance of an annular ligament biopsy in conjunction with a synovial biopsy during endoscopic carpal tunnel surgery would allow for the evaluation of the diagnostic concordance of the ligament biopsy by comparing it to the results obtained using the gold standard method. This strategy would also provide an opportunity to analyze the feasibility of systematic screening for ATTR on the ligament during endoscopic procedures.\n\nThis approach could offer a practical and innovative method for the early identification of at-risk patients and facilitate appropriate and timely management of the condition.",[27,28],"Carpal Tunnel","Transthyretin Amyloidosis","RECRUITING","2026-06-08",{"date":32,"type":33},"2026-06-12","ACTUAL",{"date":35,"type":33},"2026-05-27",{"date":37,"type":21},"2027-05-27",{"name":39,"class":40},"Clinique Saint Jean, France","OTHER",1,{"id":43,"slug":44,"hasResults":11,"nctId":45,"briefTitle":46,"officialTitle":47,"acronym":4,"eligibilityCriteria":48,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":49,"targetDuration":4,"studyType":22,"phases":51,"briefSummary":52,"conditions":53,"keywords":55,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":58,"lastUpdatePostDateStruct":59,"startDateStruct":61,"completionDateStruct":63,"leadSponsor":65,"locationsCount":41},"100568384","tourniquet-use-in-hallux-valgus-surgery-100568384","NCT06680518","Tourniquet Use in Hallux Valgus Surgery","Prospective, Randomized Study of Tourniquet Use in Hallux Valgus Surgery","Inclusion Criteria:\n\n* Patients over 18 who has been informed and has signed the consent form\n* Patient to be operated on for bilateral hallux valgus with no difference in the procedure performed between the 2 feet, the deformity must not differ by more than 10° (angle M1P1) between the 2 sides.\n* Surgery planned on the same day for both feet\n\nExclusion Criteria:\n\n* Arthritic hallux valgus requiring arthrodesis\n* Inflammatory pathology (rheumatoid arthritis, etc.)",{"count":50,"type":21},44,[24],"Prospective, single-center, randomized interventional clinical trial of tourniquet use in hallux valgus surgery. Patients will be their own controls.",[54],"Hallux Valgus",[56,57],"hallux valgus","tourniquet","2026-06-02",{"date":60,"type":33},"2026-06-04",{"date":62,"type":33},"2024-10-09",{"date":64,"type":21},"2026-12",{"name":39,"class":40},{"id":67,"slug":68,"hasResults":11,"nctId":69,"briefTitle":70,"officialTitle":71,"acronym":72,"eligibilityCriteria":73,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":74,"targetDuration":4,"studyType":22,"phases":76,"briefSummary":77,"conditions":78,"keywords":4,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":81,"lastUpdatePostDateStruct":82,"startDateStruct":84,"completionDateStruct":85,"leadSponsor":87,"locationsCount":41},"100618708","postoperative-complications-of-ankle-arthroscopy-100618708","NCT07335133","Postoperative Complications of Ankle Arthroscopy","Short- and Medium-term Postoperative Complications of Ankle Arthroscopy","ARTHRO2025","Inclusion Criteria:\n\n* Adult patient who has been informed and has signed the consent form\n* Patient scheduled for arthroscopic ankle surgery.\n* Patient affiliated with or covered by a health insurance plan\n\nExclusion Criteria:\n\n* Recent traumatic injury (less than 1 month old), physical therapy assessment impossible\n* Inability to follow up for up to one year\n* Patient under legal protection\n* Pregnant woman, patient under guardianship or conservatorship\n* Patient who has already undergone ankle surgery",{"count":75,"type":21},150,[24],"The goal of this clinical trial is to describe complications that occurred in the year following surgery, based on follow-up surgical consultations and physical therapy sessions.\n\nThe target population is any adult patient who has undergone ankle surgery performed under arthroscopy.\n\nPrimary outcome is description of all complications occurring within one year following ankle arthroscopy. This description will be based on clinical and functional examinations performed by surgeons and physical therapists.\n\nParticipants will be regularly monitored by the surgeon and physical therapist (15 days postoperative, 3 months, 6 months, and 1 year).\n\nThey will complete self-assessment questionnaires and undergo functional physical therapy tests, including ALR RSI, FAAM AVQ, FAAM Sport, CAIT, and Ankle Go.",[79,80],"Ankle Injuries and Disorders","Surgery Complications","2026-01-05",{"date":83,"type":33},"2026-01-12",{"date":81,"type":33},{"date":86,"type":21},"2028-06",{"name":39,"class":40},{"id":89,"slug":90,"hasResults":11,"nctId":91,"briefTitle":92,"officialTitle":93,"acronym":94,"eligibilityCriteria":95,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":96,"targetDuration":4,"studyType":22,"phases":98,"briefSummary":99,"conditions":100,"keywords":4,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":102,"lastUpdatePostDateStruct":103,"startDateStruct":105,"completionDateStruct":107,"leadSponsor":109,"locationsCount":41},"100516261","echo-guided-transverse-abdominal-plane-block-tap-in-anterior-lumbar-arthrodesis-alif-100516261","NCT06002217","Echo-guided Transverse Abdominal Plane Block (TAP) in Anterior Lumbar Arthrodesis (ALIF)","Echo-guided Transverse Abdominal Plane Block (TAP) in Anterior Lumbar Arthrodesis (ALIF): Randomized, Double-blind, Controlled Trial.","TAP ALIF","Inclusion Criteria:\n\nPatient affiliated or entitled to a social security plan.\n\n* Patient who has been informed about the study and has co-signed a consent form with the investigator. consent to participate in the study.\n* Patients over 18 years of age scheduled for abdominal disc surgery on one or two levels.\n* Patient with ASA criteria 1, 2 and 3.\n\nExclusion Criteria:\n\n* Patients with intolerance or contraindication to paracetamol, anti-inflammatory or morphine.\n* Patients allergic to local anesthetics.\n* Pregnant or breast-feeding patient.\n* patient undergoing cancer or trauma surgery trauma.\n* Patient participating in another interventional study.\n* Patient with a history of lumbar arthrodesis.\n* Patient refusing to sign consent form.\n* Patient unable to give informed consent.\n* Patient under court protection, guardianship or trusteeship.\n* Patient not available for study follow-up.",{"count":97,"type":21},80,[24],"The goal of this interventional study is to is to compare the effect of a tap block versus a placebo in patients undergoing anterior lumbar spine surgery.\n\nThe main question it aims to answer :\n\n• whether tap block can reduce the need for postoperative pain medication Participants will be randomized into two groups and all postoperative pain medication will be recorded over 3 days.\n\nResearchers will compare tap block vs placebo to see if it reduces postoperative pain.",[101],"Fusion of Spine, Lumbar Region","2026-01-02",{"date":104,"type":33},"2026-01-06",{"date":106,"type":33},"2024-02-05",{"date":108,"type":21},"2026-10",{"name":39,"class":40},{"id":111,"slug":112,"hasResults":11,"nctId":113,"briefTitle":114,"officialTitle":115,"acronym":4,"eligibilityCriteria":116,"healthyVolunteers":11,"sex":17,"minAge":117,"maxAge":4,"enrollmentInfo":118,"targetDuration":4,"studyType":22,"phases":120,"briefSummary":121,"conditions":122,"keywords":124,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":127,"lastUpdatePostDateStruct":128,"startDateStruct":130,"completionDateStruct":132,"leadSponsor":134,"locationsCount":41},"100585589","clube-ube-stability--dynamic-radio-100585589","NCT06904326","CLUBE (UBE Stability \u002F Dynamic Radio)","Assessment of Spinal Stability by Dynamic Radiography After Unilateral Biportal Endoscopic Lumbar Decompression Surgery","Inclusion Criteria:\n\n* Patient ≥ 50 ans,\n* Patient requiring single-level or 2-levels lumbar decompression surgery under UBE,\n* Patients who underwent dynamic radiography within 3 months prior to surgery,\n* Patient who received information on the study and who signed the consent form.\n\nExclusion Criteria:\n\n* Presence of a mobile spondylolisthesis with a ≥ 3 mm difference between flexion and extension movements on preoperative dynamic radiography,\n* Patient with history of lumbar arthrodesis,\n* Patient not available for study follow-up.","50 Years",{"count":119,"type":21},400,[24],"Degenerative pathologies of the spine affect a large proportion of the increasingly ageing population, and are a major public health issue. When conservative treatments (physiotherapy, analgesics, infiltrations) fail, surgical treatment is preferred.\n\nTraditionally, a simple lumbar recalibration operation is preferred (bilateral laminectomy decompression), but this may affect spinal stability. In cases of spondylolisthesis or preoperative instability, lumbar fusion (arthrodesis) is sometimes necessary to avoid the risk of major instability, but such an operation is not without risk and may require repeat surgery.\n\nThe development of new surgical techniques such as uni or bilateral laminotomies, which are less radical, has made it possible to avoid some arthrodeses. Nowadays, the emergence of new surgical techniques such as endoscopy has further reduced the risk of destabilization (shorter post-operative convalescence, less atrophy of the paraspinal muscles) and improved surgeon comfort (better vision and easier instrument handling).\n\nUnilateral biportal endoscopy (UBE) is one of two endoscopic techniques and has proven its effectiveness for lumbar decompression in terms of clinical benefits. However, there is no scientific evidence on spinal stability after recalibration under UBE.\n\nWe believe that minimizing invasiveness with UBE during simple lumbar recalibration surgery can preserve spinal stability, thereby reducing the need for lumbar fixation and lowering the cost of care.\n\nWe therefore propose to study the maintenance of spinal stability using dynamic radiography at 3 months post-operatively in patients undergoing lumbar recalibration surgery with UBE.",[123],"Spinal Instability",[125,126],"biportal endoscopy","lumbar surgery","2025-11-21",{"date":129,"type":33},"2025-11-26",{"date":131,"type":33},"2025-05-22",{"date":133,"type":21},"2027-08",{"name":39,"class":40},{"id":136,"slug":137,"hasResults":11,"nctId":138,"briefTitle":139,"officialTitle":140,"acronym":141,"eligibilityCriteria":142,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":143,"targetDuration":4,"studyType":22,"phases":145,"briefSummary":146,"conditions":147,"keywords":149,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":127,"lastUpdatePostDateStruct":152,"startDateStruct":154,"completionDateStruct":156,"leadSponsor":158,"locationsCount":41},"100431935","erector-spinae-plane-block-in-lumbar-spinal-fusion-100431935","NCT04904575","Erector Spinae Plane Block in Lumbar Spinal Fusion","Erector Spinae Plane Block in Lumbar Spinal Fusion : Double-blind, Randomized Controlled Trial.","MERFUSION","Inclusion Criteria:\n\n* Patient with medical insurance.\n* Patient who received information about study and signes a consent to participate in the study.\n* Major patient requiring a lumbar spinal fusion surgery.\n* Patient with an ASA score of 1, 2 or 3.\n\nExclusion Criteria:\n\n* Minor patient.\n* Patient with morphine intolerance\n* Patient with allergy to local anesthetics.\n* Patient consuming morphine for more than 3 months.\n* Pregnant or breastfeeding patient.\n* Patient scheduled for cancer surgery or trauma surgery.\n* Patient participating in another interventional study.\n* Patient with history of lumbar spinal fusion.\n* Patient requiring lumbar surgery without arthrodesis.\n* Patient requiring lumbar surgery with inter-lamar or inter-epineal stabilization.\n* Patient refusing to sign the consent form.\n* Patient for whom it is impossible to give informed information.\n* Patient under the protection of justice, under curatorship or under tutorship.",{"count":144,"type":21},130,[24],"The aim of this study is to observe or not a reduction in the consumption of morphine within 72 hours of the realization of an erector spinae plane block when preparing for a lumbar spinal fusion.",[148],"Lumbar Spinal Fusion",[150,151],"Erector spinae plane block","consumption of morphine",{"date":153,"type":33},"2025-11-24",{"date":155,"type":33},"2022-01-03",{"date":157,"type":21},"2026-12-31",{"name":39,"class":40},{"id":160,"slug":161,"hasResults":11,"nctId":162,"briefTitle":163,"officialTitle":164,"acronym":4,"eligibilityCriteria":165,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":166,"targetDuration":4,"studyType":22,"phases":168,"briefSummary":169,"conditions":170,"keywords":4,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":172,"lastUpdatePostDateStruct":173,"startDateStruct":175,"completionDateStruct":177,"leadSponsor":179,"locationsCount":41},"100605971","treatment-of-peritrapezial-osteoarthritis-with-isolated-trapeziometacarpal-arthroplasty-in-300-patients-100605971","NCT07169474","Treatment of Peritrapezial Osteoarthritis With Isolated Trapeziometacarpal Arthroplasty in 300 Patients","Treatment of Peri-trapezial Osteoarthritis With Isolated Trapeziometacarpal Arthroplasty","Inclusion Criteria:- Patients over 18 years of age who are members or beneficiaries of french social security\n\n* Patient requiring surgical management\n* Clinical and radiographic diagnosis of peri-trapezial osteoarthritis in the 1 or 2 joints:\n\nTM osteoarthritis: glickel sign + grinding test STT osteoarthritis: pain on wrist mobilization in flexion-extension and prono-supination\n\n* TM (Eaton-Littler stages II to III) and STT (Crosby stages II and III) radiographic osteoarthritis\n* Persistent pain and functional limitations despite conservative treatment for at least 6 months (combining intermittent immobilization of wrist and thumb + joint infiltration of the 2 joints)\n* Ability to understand and sign the informed consent form.\n\nExclusion Criteria:\n\n* History of surgery on the affected thumb.\n* Systemic inflammatory diseases (e.g. rheumatoid arthritis).\n* Active infection or history of joint infection of the upper limb.\n* Inability to participate in post-operative follow-up.",{"count":167,"type":21},300,[24],"The aim of this clinical trial is to assess the functional outcomes of isolated trapeziometacarpal joint arthroplasty in adult patients requiring surgical management of trapeziometacarpal osteoarthritis, with or without associated symptoms.\n\nThe primary endpoint is the evolution of the Quick DASH functional score between inclusion (preoperative) and one year postoperatively.\n\nThe study design is a follow-up study of a multicenter cohort.",[171],"Trapeziometacarpal Osteoarthritis","2025-11-20",{"date":174,"type":33},"2025-11-25",{"date":176,"type":33},"2025-09-09",{"date":178,"type":21},"2027-07-30",{"name":39,"class":40},""]