[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Clinique Victor Pauchet\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":62},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,40],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":14,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":4,"overallStatus":27,"whyStopped":4,"lastUpdateSubmitDate":28,"lastUpdatePostDateStruct":29,"startDateStruct":32,"completionDateStruct":34,"leadSponsor":36,"locationsCount":39},"100598664","comparative-study-of-high-frequency-pulsed-vacuum-technology-versus-phacoemulsification-for-cataract-surgery-100598664",false,"NCT07074431","\"Comparative Study of High-frequency Pulsed Vacuum Technology Versus Phacoemulsification for Cataract Surgery","PULSEM","Inclusion Criteria:\n\n* Adult patient\n* Patient with bilateral cataracts\n* Grade 1 to 3 cataracts\n* Indication for bilateral cataract surgery\n* Patient informed of the study and having given their written and signed informed consent\n* Patient affiliated with a social security scheme or beneficiary of such a scheme\n\nExclusion Criteria:\n\n* Refusal of consent\n* Cataract grade \\> 3\n* Unilateral and\u002For combined cataract surgery\n* Uveitic cataract\n* Glaucoma\n* Patient with ocular comorbidity\n* Patient with cognitive impairment preventing them from responding to satisfaction questionnaires\n* Patient unable to read, write, or understand French\n* Pregnant or breastfeeding patient as defined in Article L1121-5 of the French Public Health Code\n* Vulnerable patient as defined in Article L1121-6 of the French Public Health Code\n* Adult patient under guardianship, curatorship, or legal protection\n* Patient unable to give personal consent","ALL","18 Years",{"count":19,"type":20},60,"ESTIMATED","INTERVENTIONAL",[23],"NA","Cataracts are cloudings of the lens, primarily due to aging. Surgery is the primary treatment for cataracts. The most commonly used surgical technique is phacoemulsification, which involves fragmenting the lens using a high-frequency ultrasound probe and removing the fragments. Phacoemulsification is more common due to its advantages.\n\nRecently, a new approach has emerged, using high-frequency pulsed vacuum technology for cataract ablation. This less invasive approach is expected to allow for faster patient recovery and reduce surgical risks. High-frequency pulsed vacuum utilizes the pulse-pulse principle by interrupting the vacuum every tenth of a second. This interruption creates an impact moment between the cataract material and the cannula tip, dissecting the cataract without damaging the surrounding delicate tissue. High-frequency pulsed vacuum maintains anterior chamber stability while creating sufficient dissection to aspirate the cataract material. This energy also cools the tip, allows for better vacuum control, and significantly reduces turbulence within the eye. More importantly, high-frequency pulsed vacuum disrupts endothelial cells less and causes less edema than mechanical ultrasound.\n\nThis technique therefore appears ideal for treating patients with at-risk corneas (low endothelial cell count, risk of decompensation and corneal transplantation).\n\nThe objective of the study is to demonstrate the benefits of this approach using high-frequency pulsed vacuum technology through a randomized, comparative, crossover study.",[26],"Cataract Bilateral","RECRUITING","2026-03-26",{"date":30,"type":31},"2026-03-31","ACTUAL",{"date":33,"type":31},"2025-12-12",{"date":35,"type":20},"2027-01",{"name":37,"class":38},"Clinique Victor Pauchet","OTHER",1,{"id":41,"slug":42,"hasResults":11,"nctId":43,"briefTitle":44,"officialTitle":44,"acronym":45,"eligibilityCriteria":46,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":47,"targetDuration":4,"studyType":21,"phases":49,"briefSummary":50,"conditions":51,"keywords":4,"overallStatus":53,"whyStopped":4,"lastUpdateSubmitDate":54,"lastUpdatePostDateStruct":55,"startDateStruct":57,"completionDateStruct":59,"leadSponsor":61,"locationsCount":4},"100612975","impact-of-a-sequential-isokinetic-fatigue-protocol-followed-by-ankle-strengthening-after-botulinum-toxin-injection-into-spastic-plantar-flexors-on-foot-lift-strength-and-walking-100612975","NCT07260565","Impact of a Sequential Isokinetic Fatigue Protocol Followed by Ankle Strengthening After Botulinum Toxin Injection Into Spastic Plantar Flexors on Foot Lift Strength and Walking","ISOTOX","Inclusion Criteria:\n\n* Adult patient\n* Patient with spastic hemiplegia (regardless of cause)\n* MAS 1-2 spasticity of the plantar flexors\n* Deficit of the foot lifters at the minimum stage of contraction with movement\n* Patient who has received botulinum toxin injections in the plantar flexors\n* Patient who has been informed about the research and has given their written and signed informed consent\n* Patient affiliated with a social security scheme or beneficiary of such a scheme\n\nExclusion Criteria:\n\n* Refusal of consent\n* Patient with severe cognitive impairment (MMSE \\\u003C23\u002F30)\n* Surgery on the affected lower limb\n* Patient unable to read, write or understand French\n* Patient who is pregnant or breastfeeding, in accordance with Article L1121-5 of the CSP\n* Vulnerable patients according to Article L1121-6 of the CSP\n* Adult patients under guardianship, curatorship or judicial protection\n* Patients unable to give their consent in person according to Article L.1121-8 of the CSP or adults protected by law",{"count":48,"type":20},30,[23],"Spastic foot drop (speed- and force-dependent hypertonia) is one of the most common neuro-orthopaedic disorders following brain injury. It has a negative impact on walking and is closely linked to independence in activities of daily living.\n\nThis disorder combines a deficit in muscle strength in the plantar flexors and extensors with pathological hypertonia of the plantar flexors, causing an imbalance in ankle flexion and resulting in equinus deformity of the foot.\n\nBotulinum toxin is the first-line pharmacological treatment for focal spasticity of neurological origin, and its effectiveness is directly linked to the quality and quantity of associated rehabilitation care. However, the associated rehabilitation protocols remain vague and are based on general recommendations combining: stretching of muscles and tendons, muscle strengthening of spastic muscles, their agonists and antagonists, and functional work. The standard rehabilitation protocol used in our centre will be detailed in the study protocol.\n\nThe isokinetic dynamometer is an open-chain muscle strengthening tool that has the advantage of introducing a concept of reproducible assessment and rehabilitation.\n\nThis reproducibility is difficult to guarantee with the rehabilitation techniques practised by a therapist, whose applied force and precision may vary from one session to another. We have therefore developed a sequential muscle strengthening protocol combining strengthening work - fatigue of the triceps surae followed by muscle strengthening work of the foot lifters.\n\nThe aim of this work is to determine the effects of this protocol compared to conventional rehabilitation aimed at promoting the post-injection effects of botulinum toxin.",[52],"Spasticity of the Plantar Flexors","NOT_YET_RECRUITING","2025-12-16",{"date":56,"type":31},"2025-12-17",{"date":58,"type":20},"2026-01-01",{"date":60,"type":20},"2028-11-01",{"name":37,"class":38},""]