[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Collagen Matrix\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":119},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,5,0,[8,38,57,81,100],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":4,"briefSummary":22,"conditions":23,"keywords":4,"overallStatus":25,"whyStopped":4,"lastUpdateSubmitDate":26,"lastUpdatePostDateStruct":27,"startDateStruct":30,"completionDateStruct":32,"leadSponsor":34,"locationsCount":37},"100621474","post-market-clinical-investigation-plan-collagen-dura-regeneration-membrane---repair-dmr-100621474",false,"NCT07371091","Post-market Clinical Investigation Plan: Collagen Dura Regeneration Membrane - Repair (DMR)","Monitoring the Use of Collagen Dura Membrane - Repair (DMR) in the Post-market Phase","Inclusion Criteria:\n\n* Patients with a dural defect requiring repair with a dural substitute as per routine clinical practice\n* Patient is 18 years or older\n* Patient of child-bearing potential is not pregnant or nursing\n* Participant is willing and able to provide consent\n\nExclusion Criteria:\n\n* Patients with a known history of hypersensitivity to bovine derived materials\n* Patients that are non-English speaking\n* Patients requiring legal representation","ALL","18 Years",{"count":19,"type":20},110,"ESTIMATED","OBSERVATIONAL","Monitoring the Use of Collagen Dura Regeneration Membrane - Repair (DMR) in the Post-market Phase.",[24],"Repair of Dura Mater","NOT_YET_RECRUITING","2026-05-27",{"date":28,"type":29},"2026-05-29","ACTUAL",{"date":31,"type":20},"2026-07",{"date":33,"type":20},"2027-12",{"name":35,"class":36},"Collagen Matrix","INDUSTRY",2,{"id":39,"slug":40,"hasResults":11,"nctId":41,"briefTitle":42,"officialTitle":43,"acronym":4,"eligibilityCriteria":44,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":45,"targetDuration":4,"studyType":21,"phases":4,"briefSummary":43,"conditions":47,"keywords":4,"overallStatus":48,"whyStopped":4,"lastUpdateSubmitDate":49,"lastUpdatePostDateStruct":50,"startDateStruct":52,"completionDateStruct":54,"leadSponsor":56,"locationsCount":37},"100577733","post-market-clinical-investigation-plan--collagen-dural-regeneration-matrix-duramatrix-onlay-plus-100577733","NCT06802133","Post-Market Clinical Investigation Plan- Collagen Dural Regeneration Matrix (DuraMatrix-Onlay Plus)","Monitoring the Use of Collagen Dural Regeneration Matrix (DuraMatrix-Onlay Plus) in the Postmarket Phase.","Inclusion Criteria:\n\n* The general population will be included in the study where a dura substitute is required for the repair of dura mater.\n\nExclusion Criteria:\n\n* Patients that have conditions which are contraindicated per the instructions for use (IFU) would be excluded.",{"count":46,"type":20},118,[24],"RECRUITING","2025-10-14",{"date":51,"type":29},"2025-10-15",{"date":53,"type":29},"2025-01-13",{"date":55,"type":20},"2026-07-30",{"name":35,"class":36},{"id":58,"slug":59,"hasResults":11,"nctId":60,"briefTitle":61,"officialTitle":62,"acronym":4,"eligibilityCriteria":63,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":64,"targetDuration":4,"studyType":21,"phases":4,"briefSummary":66,"conditions":67,"keywords":70,"overallStatus":48,"whyStopped":4,"lastUpdateSubmitDate":49,"lastUpdatePostDateStruct":73,"startDateStruct":75,"completionDateStruct":77,"leadSponsor":79,"locationsCount":80},"100422031","ossimend-ba-in-posterolateral-instrumented-lumbar-fusion-100422031","NCT04775537","OssiMend BA in Posterolateral Instrumented Lumbar Fusion","OssiMend Bioactive Moldable in Posterolateral Instrumented Lumbar Fusion","Inclusion Criteria:\n\n* Subject must be 18 years of age or older at the time of consent and must have a documented diagnosis of degenerative disc disease (DDD) that has failed to respond to nonoperative treatment for at least 6 months. DDD is defined by back and\u002For radicular pain with degeneration of the disc as confirmed by medical history, physical examination, and radiographic studies that may include CT, MRI, plain X-ray film, discography, myelography, etc. with one or more of the following findings:\n\n  * Instability as defined by \\>3mm translation or \\>5 degrees angulation\n  * Osteophyte formation of facet joints or vertebral endplates\n  * Decreased disc height, on average by \\>2mm, but dependent upon the spinal level\n  * Herniated nucleus pulposus\n  * Facet joint degeneration\u002Fchanges\n\nExclusion Criteria:\n\n1. Subject is under 18 years of age at the time of consent\n2. Subject has had prior lumbar spine fusion surgery at any level\n3. Subject is currently undergoing treatment for malignancy or has undergone treatment for malignancy\n4. Subject is pregnant or nursing or planning to become pregnant during the two years (24 months) following arthrodesis\n5. Subject has an active (local or systemic) infection or is undergoing adjunctive treatment for infection\n6. Subjects under workers compensation or active litigation",{"count":65,"type":20},120,"The primary objective of this study is to measure the success rate of lumbar fusion in subjects at 12 months when instrumented lumbar arthrodesis is performed using OssiMend Bioactive Moldable as the bone grafting material",[68,69],"Spinal Disease","Degenerative Disc Disease",[71,72],"Bone Graft","Lumbar Fusion",{"date":74,"type":29},"2025-10-16",{"date":76,"type":29},"2021-01-21",{"date":78,"type":20},"2027-01-30",{"name":35,"class":36},4,{"id":82,"slug":83,"hasResults":11,"nctId":84,"briefTitle":85,"officialTitle":86,"acronym":4,"eligibilityCriteria":87,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":88,"targetDuration":4,"studyType":21,"phases":4,"briefSummary":90,"conditions":91,"keywords":4,"overallStatus":25,"whyStopped":4,"lastUpdateSubmitDate":92,"lastUpdatePostDateStruct":93,"startDateStruct":94,"completionDateStruct":96,"leadSponsor":98,"locationsCount":99},"100609634","clinical-investigation-plan---post-market-clinical-follow-up-study-collagen-dura-membrane---suturable-100609634","NCT07217132","Clinical Investigation Plan - Post-market Clinical Follow-up Study Collagen Dura Membrane - Suturable","Monitoring the Use of Collagen Dura Membrane - Suturable (DMS) in the Post-market Phase","Inclusion Criteria:\n\n* Patients with a dural defect requiring repair with a dural substitute\n* Patient is 18 years or older\n* Patient of child-bearing potential is not pregnant or nursing\n\nExclusion Criteria:\n\n* Patients with a known history of hypersensitivity to bovine derived materials\n* Patients that are non-English speaking\n* Subjects requiring Legally Authorized Representative",{"count":89,"type":20},54,"Monitoring the use of Collagen Dura Membrane - Suturable (DMS) in the post-market phase",[24],"2025-10-13",{"date":51,"type":29},{"date":95,"type":20},"2025-12-01",{"date":97,"type":20},"2027-09",{"name":35,"class":36},1,{"id":101,"slug":102,"hasResults":11,"nctId":103,"briefTitle":104,"officialTitle":105,"acronym":106,"eligibilityCriteria":107,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":108,"targetDuration":4,"studyType":21,"phases":4,"briefSummary":109,"conditions":110,"keywords":4,"overallStatus":48,"whyStopped":4,"lastUpdateSubmitDate":111,"lastUpdatePostDateStruct":112,"startDateStruct":114,"completionDateStruct":116,"leadSponsor":118,"locationsCount":99},"100579332","post-market-clinical-investigation-plan---collagen-dura-membranes-dm--dmo-100579332","NCT06822920","Post-Market Clinical Investigation Plan - Collagen Dura Membranes (DM & DMO)","Monitoring the Use of Collagen Dura Membrane in the Post-market Phase","DM&DMO","Inclusion Criteria:\n\n* Patients with a dural defect requiring repair with a dural substitute.\n\nExclusion Criteria:\n\n* There are no subject restrictions for the study other than patients with known allergy to bovine collagen products as specified in the contraindications of the Instructions for Use.",{"count":19,"type":20},"Monitoring the Use of Collagen Dura Membrane in the Post-market phase",[24],"2025-02-07",{"date":113,"type":29},"2025-02-12",{"date":115,"type":29},"2025-01-03",{"date":117,"type":20},"2025-12-30",{"name":35,"class":36},""]