[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Complejo Hospitalario Universitario de Albacete\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":82},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,46],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":31,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":34,"lastUpdatePostDateStruct":35,"startDateStruct":38,"completionDateStruct":40,"leadSponsor":42,"locationsCount":45},"100439449","rct-to-analyze-the-efficacy-of-a-spanish-healthcare-ministry-based-in-intervention-to-reduce-frailty-status-in-prefrail-older-adults-100439449",false,"NCT05002439","RCT to Analyze the Efficacy of a Spanish Healthcare ministRy Based In InTervention to Reduce Frailty Status in Prefrail Older Adults","Multicenter Randomized Clinical Trial to Analyze the Efficacy of a Spanish Healthcare ministRy Based In InTervention to Reduce Frailty Status in Prefrail Older Adults (FRAILMERIT)","FRAILMERIT","Inclusion Criteria:\n\n* Community-dwelling adults with age equal or greater than 70 years.\n* Barthel index \\> 85\n* Gait speed \\\u003C 0.8 m\u002Fs OR frailty \u002Fprefrailty using the frailty phenotype\n* Ability to realize the physical exercise program\n* Capacity to understand the procedures and interventions of the trial\n* Capacity to understand and sign the informed consent\n\nExclusion Criteria:\n\n* Major contraindications for exercise: Severe aortic valve stenosis, myocardial infarction in the previous 6 weeks, Venous thromboembolic disease in the previous 6 weeks.\n* Inability to conduct the physical tests of the trial\n* Inability to understand the procedures of the trial\n* Active solid organ or hematologic neoplasm other than basocellular skin neoplasm, or life expectancy lower than one year.\n* Surgical intervention programmed that could interfere with the physical exercise program.","ALL","70 Years","100 Years",{"count":21,"type":22},273,"ESTIMATED","INTERVENTIONAL",[25],"NA","Objectives: The main objective is to analyze the efficacy of an intervention based on the algorithm proposed by the Spanish Healtcare Ministry (see figure in annex 1) at Primary Care level to reduce Frailty status or Physical Function in community-dwelling older adults. Secondary objectives are: 1. To analyze if the intervention is cost-effective; 2. To analyze if the intervention reduces hospitalizations and emergency department visits, incident disability, falls, institutionalization, mortality, Primary Care visits and Drug use, and improves quality of life.\n\nMethodology: Multicentric Randomized Clinical Trial in 273 Prefrail or Frail or with a gait speed lower that 0.8 m\u002Fs community-dwelling women and men with an age equal or greater to 70 years, attended in selected Primary Care centers of Spain (Albacete, Hellín, Barcelona, Madrid, La Carlota, and Tacoronte). Randomization will be made by clusters, being every cluster a different Primary Care center in order to avoid contamination. Randomization on a 1:1 relationship between groups. The main outcome variable will be Frailty status or Physical function change (main composite outcome) at 8-month follow-up measured with the Frailty Phenotype and the Short Physical Performance Battery (SPPB) respectively. All instrumentation will follow the guidelines of the Spanish Healthcare Ministry algorithm for frailty updated 2022. Intervention will consist on a groupal multicomponent physical exercise program, a nutritional intervention program and a training in Frailty to Primary Care centers. The intervention will be delivered by trained experts in groups of 6 participants, and will be based on the recommendations of the Spanish Healthcare Ministry document, updated in 2022.",[28,29,30],"Frailty","Aged","Exercise",[28,29,32],"Multimodal training","RECRUITING","2025-03-14",{"date":36,"type":37},"2025-03-18","ACTUAL",{"date":39,"type":37},"2020-01-01",{"date":41,"type":22},"2025-03-31",{"name":43,"class":44},"Complejo Hospitalario Universitario de Albacete","OTHER",1,{"id":47,"slug":48,"hasResults":11,"nctId":49,"briefTitle":50,"officialTitle":51,"acronym":4,"eligibilityCriteria":52,"healthyVolunteers":11,"sex":17,"minAge":53,"maxAge":4,"enrollmentInfo":54,"targetDuration":56,"studyType":57,"phases":4,"briefSummary":58,"conditions":59,"keywords":65,"overallStatus":73,"whyStopped":4,"lastUpdateSubmitDate":74,"lastUpdatePostDateStruct":75,"startDateStruct":77,"completionDateStruct":79,"leadSponsor":81,"locationsCount":4},"100560951","incidence-and-complications-of-post-extubation-and-post-tracheostomy-dysphagia-in-adult-patients-in-the-critical-care-unit-100560951","NCT06583824","Incidence and Complications of Post-extubation and Post-tracheostomy Dysphagia in Adult Patients in the Critical Care Unit","Incidence and Complications Associated with Acquired Swallowing Disorder in the Intensive Care Unit in Extubated or Tracheotomized Patients: a Cohort Study","Inclusion Criteria:\n\nPatients aged ≥ 18 years, requiring intubation for ≥ 48 hours and\u002For subsequent tracheostomy, with an adequate level of consciousness to perform the dysphagia diagnostic test, and who have signed the consent form.\n\nExclusion Criteria:\n\nPrevious tracheostomy, prior diagnosis of dysphagia, neurodegenerative disease, or a history of stroke (CVA).","18 Years",{"count":55,"type":22},414,"6 Months","OBSERVATIONAL","Acquired Swallowing Disorder in ICU (ICU-ASD), also known as postextubation dysphagia, is a multicausal problem experienced by survivors in intensive care units (ICUs) when the efficiency, safety of swallowing, or both are compromised. These alterations can lead to an increased risk of aspiration, respiratory complications, and malnutrition, potentially resulting in prolonged hospitalization, reduced quality of life, poorer clinical outcomes, and even death.\n\nDespite the clinical and social significance of this disorder, there is limited research addressing it. Existing studies primarily focus on incidence and associated factors, with scant attention to the occurrence of complications, and there is a lack of assessment of the quality of life of these patients. In our context, healthcare professionals are increasingly recognizing the importance of this issue, although the real incidence of ICU-ASD, as well as the frequency of respiratory and nutritional complications, remains unknown. Furthermore, the quality of life of patients with this disorder has not been evaluated thus far.\n\nObjectives:Primary: To analyze the occurrence of respiratory and nutritional complications associated with ICU-ASD in patients intubated for ≥48 hours or tracheotomized in the Intensive Care Unit of the University Hospital Complex of Albacete (ICU CHUA) and identify potential factors related to their occurrence.\n\nSpecific: To determine the incidence of ICU-ASD in the polyvalent ICU CHUA, assess the frequency of respiratory complications, evaluate nutritional status, assess quality of life, and determine the mortality of study participants.\n\nMaterial and Method: Prospective observational cohort study. Setting: Polyvalent ICU CHUA. Participants: Intubated patients for ≥48 hours or tracheotomized, with signed consent. Sampling: Consecutive. Sample size: 414 participants. Demographic\u002Fclinical variables. Outcome variables: Occurrence of respiratory complications, nutritional status, quality of life. Instruments: Modified Volume-Viscosity Swallowing Test (mV-VST), Swallowing Quality of Life Questionnaire (SWAL-QoL). Dysphagia detection will occur 24 hours post-extubation and\u002For 4 days after tracheotomy. Follow-up during hospitalization and post-ICU discharge until the outpatient consultation. Statistical analysis: Absolute and relative frequencies, measures of central tendency and dispersion, significance level of p \\< 0.05, 95% CI; Bivariate analysis: Checking group homogeneity and hypothesis testing: Chi-square, Student\\'s t-test, U-Mann-Whitney, ANOVA, or Kruskal-Wallis.",[60,61,62,63,64],"Respiratory Complications","Pneumonia","Quality of Lifte","Death","Swallowing Disorder.Other Specified",[66,67,68,69,70,71,72],"dysphagia","tracheostomy","aspiration","malnutrition","critical care","mechanical ventilation","pneumonia","NOT_YET_RECRUITING","2024-09-03",{"date":76,"type":37},"2024-09-04",{"date":78,"type":22},"2024-09-10",{"date":80,"type":22},"2026-09-30",{"name":43,"class":44},""]