[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Concordia University, Montreal\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":107},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,42,79],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":14,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":22,"studyType":23,"phases":4,"briefSummary":24,"conditions":25,"keywords":4,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":30,"lastUpdatePostDateStruct":31,"startDateStruct":34,"completionDateStruct":36,"leadSponsor":38,"locationsCount":41},"100632581","acute-and-chronic-effects-of-obesity-100632581",false,"NCT07515547","Acute and Chronic Effects of Obesity","ACEO","Inclusion Criteria:\n\nWe are recruiting two groups of sedentary or untrained males and pre-menopausal females (age 25-40 years) with body mass indices (BMI) between 30.0-39.9 kg\u002Fm\\^2. All participants will be required to provide a medical record and\u002For photographic evidence of weight at childhood (around age of 10-17 years old). Individuals with BMI between 40.0-41.9 may be included in the case that an individual with a much shorter height falls within this range, as BMI does not always properly define obesity type. Once the participant completes their DEXA scan, we will be able to more accurately assess the participant's obesity level and re-evaluate their elgibility.\n\nExclusion criteria:\n\nParticipants will be excluded if they are pregnant or planning to become pregnant, breast-feeding, presently using nicotine containing products (e.g. cigarettes, chewing tobacco, nicotine gum etc.), taking certain anti-depressants and anti-hypertensives. More modern medications will not need to be excluded as they don't affect weight loss or weight gain. As medication use will be screened, if the participant is using medications that do not affect our outcomes they will be included in the study. Participants will also be excluded if they have had any surgery (e.g. gastric bypass, magnetic implants) or have any conditions (e.g. iron deficiency anemia) or diseases (e.g. diabetes, cancer, IBD, history of eating disorders or mental illness) that may affect immune function and thus study outcomes, or the ability to participate in the study.\n\nParticipants must also have been weight stable for at least 2 months.","ALL","25 Years","40 Years",{"count":20,"type":21},150,"ESTIMATED","6 Months","OBSERVATIONAL","The goal of this study is to understand if there are differences in the fat, muscle and metabolism of individuals who developed obesity during childhood versus those who developed obesity in adulthood. We will do this by having recruited participants undergo subcutaneous adipose tissue biopsies in the abdomen and thigh, a muscle biopsy in the thigh, collect blood and urine samples, a DEXA scan and 3 submaximal exercise tests. participants will also have their resting energy expenditure measured through indirect calorimetry to tailor a targeted weight loss protocol through caloric restriction and cardiovascular exercise (3 times a week). After 10% of weight loss is completed, study participants will repeat all tests during a 2 week weight stabilization period. At 12 weeks into the intervention, indirect calorimetry, DEXA scan and blood tests will be repeated.",[26,27,28],"Obesity & Overweight","Metabolism Changes","Lipid Metabolism","RECRUITING","2026-03-31",{"date":32,"type":33},"2026-04-07","ACTUAL",{"date":35,"type":33},"2025-04-30",{"date":37,"type":21},"2029-08",{"name":39,"class":40},"Concordia University, Montreal","OTHER",2,{"id":43,"slug":44,"hasResults":11,"nctId":45,"briefTitle":46,"officialTitle":46,"acronym":4,"eligibilityCriteria":47,"healthyVolunteers":48,"sex":16,"minAge":49,"maxAge":50,"enrollmentInfo":51,"targetDuration":4,"studyType":23,"phases":4,"briefSummary":53,"conditions":54,"keywords":60,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":70,"lastUpdatePostDateStruct":71,"startDateStruct":73,"completionDateStruct":75,"leadSponsor":77,"locationsCount":78},"100568382","the-role-of-nutrition-in-muscle-function-of-bariatric-surgery-patients-100568382","NCT06680492","The Role of Nutrition in Muscle Function of Bariatric Surgery Patients","Inclusion Criteria:\n\n* Male and female\n* Aged 18 to 65 years old\n* Undergoing first bariatric surgery (any type)\n* Diabetics and non-diabetics\n* Non-smokers and non-cannabis consumers\n\nExclusion Criteria:\n\n* Pregnant and breastfeeding women\n* Individuals undergoing second bariatric surgery\n* Regular smokers and cannabis consumers\n* Current use of Ozempic (or Ozempic-like medication) and anti-psychotic meds\n* Limited physical mobility (using walking aids such as canes, walkers, or wheelchairs) and issues with hand resistance\n* Kidney disease, non-controlled \u002F unstable hypertension and hypothyroidism, and any metabolic disease other than diabetes",true,"18 Years","65 Years",{"count":52,"type":21},75,"Current recommendations for protein intake after bariatric surgery are not based on strong scientific evidence. It remains unclear how much protein should be eaten to minimize muscle loss and preserve the metabolism and function of individuals post-bariatric surgery.\n\nThe objective of this study is to analyze the relationships between changes in body composition, nutrition and protein intake, and muscle function after bariatric surgery to further our understanding of the nutritional needs of patients after bariatric surgery.\n\nWe intend to recruit around 75 participants, men and women, aged between 18 and 65 years. Participants will be recruited from the Bariatric Surgery Clinic, McGill University Health Center.",[55,56,57,58,59],"Obesity, Diabetes, Nutrition, Physical Health","Body Composition Changes","Muscle Function, Handgrip Strength Test","Protein Metabolism","Bariatric Surgery Patients",[61,62,63,64,65,66,67,68,69],"Obesity","Bariatric sugery","Protein function","Muscle function","6-Minute Walk Test","Handgrip Strength Test","Nutritional needs","Nutritional guides","Nutrition","2024-11-06",{"date":72,"type":33},"2024-11-08",{"date":74,"type":33},"2017-06-23",{"date":76,"type":21},"2026-01",{"name":39,"class":40},1,{"id":80,"slug":81,"hasResults":11,"nctId":82,"briefTitle":83,"officialTitle":83,"acronym":4,"eligibilityCriteria":84,"healthyVolunteers":48,"sex":16,"minAge":49,"maxAge":50,"enrollmentInfo":85,"targetDuration":87,"studyType":23,"phases":4,"briefSummary":88,"conditions":89,"keywords":94,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":99,"lastUpdatePostDateStruct":100,"startDateStruct":102,"completionDateStruct":104,"leadSponsor":106,"locationsCount":78},"100562121","regional-adipose-tissue-characteristics-in-type-ii-diabetes-100562121","NCT06599047","Regional Adipose Tissue Characteristics in Type II Diabetes","Inclusion Criteria:\n\n* Men, premenopausal and postmenopausal females between 18-65 years\n* Anticipating having bariatric surgery (participants with obesity) or general surgery in the abdominal area (normal weight participants) with a duration of less than 1.5 hours.\n* BMI 30 kg \u002F m2 (participants with obesity)\n* Weight Stable for a minimum of two months prior to the first pre-op visit\n\nExclusion Criteria:\n\n* Smoking\n* Renal impairment defined by creatinine clearance; 60 ml\u002Fminute\n* Uncontrolled hypothyroidism\n* No comorbidity other than diabetes type II Exceptions: controlled hypertension, hypothyroidism controlled, controlled dyslipidemia\n* Use prescribed medication that affect our outcomes E.g. Exceptions include metformin, DPP-4 inhibitors, inhibitors of the α-glucosidase, hypotensive with a stable dose for 3 months lipid lowering with a stable dose for 3 months.",{"count":86,"type":21},140,"1 Year","Fat tissue in different parts of the body has different characteristics. Several studies have associated abdominal fat to an increased risk for multiple metabolic diseases, such as type 2 diabetes and cardiovascular disease, compared with fat located under the skin at the hips and thighs. However, the investigators do not know how the abdominal fat causes or contributes to the development of these diseases or how the development of these disease may in turn cause or contribute to changes in the fat tissue. The general objective of this study is to understand these mechanisms.\n\nTo investigate these questions, the study will recruit 140 participants, both men and women aged 18-65 years. The participants will be divided into three groups: 40 people with obesity, 40 with diabetes, and 60 lean individuals. Participants will be recruited from patients at the CIUSSS du Nord-de-l'Île-de Montréal - Hôpital du Sacré-Coeur de Montréal who are awaiting bariatric or general abdominal surgery, as well as from the general population in the Montreal area.",[90,91,92,93],"Obesity and Type 2 Diabetes","Bariatric Patients Undergoing Bariatric Surgery","Adipose Tissue Dysfunction Type 2 Diabetes Mellitus Bariatric Surgery","Adipose Tissue Inflammation",[95,96,97,98,93],"obesity","Type 2 diabetes","Bariatric Surgery","Adipose Tissue Characterization","2024-10-20",{"date":101,"type":33},"2024-10-22",{"date":103,"type":33},"2016-05-01",{"date":105,"type":21},"2025-12",{"name":39,"class":40},""]