[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"CooperVision International Limited (CVIL)\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":146},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,6,0,[8,41,63,84,103,124],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":4,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":29,"lastUpdatePostDateStruct":30,"startDateStruct":33,"completionDateStruct":35,"leadSponsor":37,"locationsCount":40},"100636480","evaluation-of-contact-lenses-and-myopia-100636480",false,"NCT07566234","Evaluation of Contact Lenses and Myopia.","Myopia Prevention Study in Chinese Population With Dual Focus Myopia Control Lenses.","Inclusion Criteria:\n\n1. Male and female children aged between 8-10 years inclusive.\n2. Cycloplegic SER from -0.25 (non-inclusive) to +0.75 D (inclusive) in both eyes.\n3. Astigmatism ≤ -1.00D in both eyes.\n4. Un-corrected visual acuity (UCVA) ≤ 0.1 LogMAR.\n5. As applicable (dependent on local requirements), the subject and parent\u002Flegal guardian will have read the Informed Assent\u002FConsent, been given an explanation of the study, indicated an understanding and signed the forms.\n6. Along with their parent or guardian, be capable of comprehending the nature of the study, and be willing and able to adhere to the instructions set forth in this protocol.\n7. Along with their parent or guardian, agree to maintain the visit schedule and be able to keep all appointments as specified in the study protocol for the duration of the study.\n8. Agree and able to wear the assigned contact lenses successfully for a minimum of 10 hours per day, at least 6 days per week, for the duration of the study and to inform the study investigator if this schedule is interrupted. (Wearing time may be modified by the study staff for health reasons.)\n9. Be in good general health, based on his\u002Fher and parent's\u002Fguardian's knowledge.\n10. Any history of myopia control interventions with in 1 month must complete a 4-weeks of washout period.\n\nExclusion Criteria:\n\n1. History of myopia control intervention (e.g., atropine, orthokeratology, soft myopia control contact lenses, red light therapy, etc. over more than 1 month)\n2. Currently wears rigid gas permeable contact lenses, including orthokeratology lenses.\n3. Current use of systemic or ocular or medications which may affect contact lens wear, tear film production, pupil size, accommodation or refractive state.\n4. Ocular or systemic disease that contraindicates contact lens wear.\n5. Active allergic conjunctivitis.\n6. Any ocular, systemic or neuro-developmental conditions that could influence refractive development.\n7. Keratoconus or an irregular cornea.\n8. History of clinically significant binocular vision abnormality or strabismus.\n9. Any active anterior segment finding that would contraindicate contact lens wear.\n10. The investigator for any reason considers that it is not in the best interest of the subject to participate in the study.","ALL","8 Years","10 Years",{"count":20,"type":21},110,"ESTIMATED","INTERVENTIONAL",[24],"NA","This study will evaluate the effect of dual focus contact lenses on Myopia prevention.",[27],"Pre-myopia","NOT_YET_RECRUITING","2026-05-20",{"date":31,"type":32},"2026-05-22","ACTUAL",{"date":34,"type":21},"2026-05",{"date":36,"type":21},"2029-05",{"name":38,"class":39},"CooperVision International Limited (CVIL)","INDUSTRY",1,{"id":42,"slug":43,"hasResults":11,"nctId":44,"briefTitle":45,"officialTitle":46,"acronym":4,"eligibilityCriteria":47,"healthyVolunteers":11,"sex":16,"minAge":48,"maxAge":4,"enrollmentInfo":49,"targetDuration":4,"studyType":22,"phases":51,"briefSummary":52,"conditions":53,"keywords":4,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":55,"lastUpdatePostDateStruct":56,"startDateStruct":57,"completionDateStruct":59,"leadSponsor":61,"locationsCount":62},"100638895","contact-lens-trial-fitting-experience-100638895","NCT07600645","Contact Lens Trial Fitting Experience","Assessment of a Novel Multifocal Contact Lens Trial Fitting Experience","Inclusion Criteria:\n\n1. They are at least 40 years of age.\n2. They understand their rights as a research participant and are willing and able to sign a Statement of Informed Consent.\n3. They habitually wear MyDay sphere or MyDay Energys contact lenses (including sphere lenses for monovision, or sphere lenses for distance vision correction and spectacles for near vision correction).\n4. They have a minimum reading add of +0.75DS (based on their manifest refraction) and no more than +2.50DS.\n5. They have spherical equivalent refractive error between +4.50 to -11.00DS (some restrictions apply based on near add availability)\n6. They have refractive astigmatism of no greater than 0.75DC in each eye.\n7. They are able to achieve distance HCHL visual acuity of +0.10 logMAR or better in each eye with manifest refraction.\n8. They report at least one near-vision difficult symptom consistent with presbyopia as evidenced by a response of 'slight difficult' or worse on ³ 1 item of the Near Activity Visual Questionnaire (NAVQ-P) at screening.\n\nExclusion Criteria:\n\n1. Is participating in any concurrent clinical or research trial.\n2. They have an ocular disorder which would normally contraindicate contact lens wear.\n3. They have a systemic disorder which would normally contraindicate contact lens wear.\n4. They are pseudophakic or aphakic.\n5. They have had corneal refractive surgery.\n6. They have any corneal distortion resulting from previous hard or rigid lens wear or have keratoconus.\n7. Is using any systemic or topical medications that in the opinion of the investigator may affect contact lens wear or a study outcome variable.\n8. Self-reports as pregnant, lactating or planning a pregnancy at the time of enrollment.","40 Years",{"count":50,"type":21},25,[24],"This study will assess a trial fitting experience with contact lenses.",[54],"Presbyopia","2026-05-18",{"date":31,"type":32},{"date":58,"type":21},"2026-05-31",{"date":60,"type":21},"2026-09-01",{"name":38,"class":39},2,{"id":64,"slug":65,"hasResults":11,"nctId":66,"briefTitle":67,"officialTitle":67,"acronym":4,"eligibilityCriteria":68,"healthyVolunteers":11,"sex":16,"minAge":69,"maxAge":4,"enrollmentInfo":70,"targetDuration":4,"studyType":22,"phases":72,"briefSummary":73,"conditions":74,"keywords":4,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":77,"lastUpdatePostDateStruct":78,"startDateStruct":80,"completionDateStruct":81,"leadSponsor":83,"locationsCount":40},"100635772","optimization-for-toric-contact-lenses-100635772","NCT07557030","Optimization for Toric Contact Lenses","Inclusion Criteria:\n\n1. They are at least 18 years of age.\n2. They understand their rights as a research participant and are willing and able to sign a Statement of Informed Consent.\n3. They have spherical refractive error at the corneal plane between +4.00 to -7.00DS\n4. They have refractive astigmatism at the corneal plane of 0.75 to 2.25DC in one eye.\n5. They are able to achieve distance HCHL visual acuity of +0.10 logMAR or better in each eye\n6. They are a current soft contact lens wearer or have previous experience of successful soft contact lens wear in the past 3 years.\n\nExclusion Criteria:\n\n1. Is participating in any concurrent clinical or research trial.\n2. They have an ocular disorder which would normally contra-indicate contact lens wear.\n3. They have a systemic disorder which would normally contra-indicate contact lens wear.\n4. They are pseudophakic or aphakic.\n5. They have had corneal refractive surgery.\n6. They have any corneal distortion resulting from previous hard or rigid lens wear or have keratoconus.\n7. Is using any systemic or topical medications that in the opinion of the investigator may affect contact lens wear or a study outcome variable.","18 Years",{"count":71,"type":21},45,[24],"The aim of this study is to evaluate the agreement between subjective and objective toric lens prescriptions.",[75,76],"Astigmatism","Ametropia","2026-05-04",{"date":79,"type":32},"2026-05-06",{"date":34,"type":21},{"date":82,"type":21},"2026-08",{"name":38,"class":39},{"id":85,"slug":86,"hasResults":11,"nctId":87,"briefTitle":88,"officialTitle":88,"acronym":4,"eligibilityCriteria":89,"healthyVolunteers":11,"sex":16,"minAge":69,"maxAge":4,"enrollmentInfo":90,"targetDuration":4,"studyType":22,"phases":92,"briefSummary":93,"conditions":94,"keywords":4,"overallStatus":95,"whyStopped":4,"lastUpdateSubmitDate":96,"lastUpdatePostDateStruct":97,"startDateStruct":99,"completionDateStruct":101,"leadSponsor":102,"locationsCount":40},"100627132","performance-of-two-daily-disposable-multifocal-contact-lenses-100627132","NCT07444658","Performance of Two Daily Disposable Multifocal Contact Lenses","Inclusion Criteria:\n\n1. They are at least 18 years of age.\n2. They understand their rights as a research participant and are willing and able to sign a Statement of Informed Consent.\n3. They habitually use soft contact lenses (multifocal soft contact lenses, sphere lenses for monovision, or sphere lenses for distance vision correction and spectacles for near vision correction,) and have worn lenses at least 3 days a week for at least the past six months.\n4. They have a minimum reading add of +0.75DS (based on their spectacle refraction)\n5. They have spherical equivalent refractive error between +6.00 to -10.00DS at the corneal plane and refractive astigmatism of no greater than -0.75DC in each eye.\n6. They are able to achieve distance HCHL visual acuity of +0.10 logMAR or better in each eye.\n\nExclusion Criteria:\n\n1. They have an ocular disorder which would normally contra-indicate contact lens wear.\n2. They have a systemic disorder which would normally contra-indicate contact lens wear.\n3. They are aphakic.\n4. They have had corneal refractive surgery.\n5. They have any corneal distortion resulting from previous hard or rigid lens wear or have keratoconus.",{"count":91,"type":21},35,[24],"This study will compare the performance of two daily disposable multifocal soft contact lenses.",[54],"RECRUITING","2026-04-06",{"date":98,"type":32},"2026-04-08",{"date":100,"type":32},"2026-02-24",{"date":58,"type":21},{"name":38,"class":39},{"id":104,"slug":105,"hasResults":11,"nctId":106,"briefTitle":107,"officialTitle":107,"acronym":4,"eligibilityCriteria":108,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":109,"enrollmentInfo":110,"targetDuration":4,"studyType":112,"phases":4,"briefSummary":113,"conditions":114,"keywords":4,"overallStatus":95,"whyStopped":4,"lastUpdateSubmitDate":115,"lastUpdatePostDateStruct":116,"startDateStruct":118,"completionDateStruct":120,"leadSponsor":122,"locationsCount":123},"100585455","north-american-comfilcon-a-clinical-study-100585455","NCT06902584","North American Comfilcon A Clinical Study","Inclusion Criteria:\n\n1. Age 8 to 75 years (inclusive).\n2. Current wearer of the Comfilcon A sphere, toric, multifocal, toric multifocal or Energys contact lens for at least 12 months.\n3. At least occasional overnight wear in the last 12 months.\n\nExclusion Criteria:\n\n1\\. Current participation in a contact lens or contact lens care product clinical trial.","75 Years",{"count":111,"type":21},182,"OBSERVATIONAL","The main objective of this study is to demonstrate acceptable safety and effectiveness (performance) of comfilcon A Sphere, Toric, Multifocal, Toric Multifocal and Energys lenses, when used in the general population.",[75,54,76],"2025-08-25",{"date":117,"type":32},"2025-08-27",{"date":119,"type":32},"2025-02-05",{"date":121,"type":21},"2025-12",{"name":38,"class":39},4,{"id":125,"slug":126,"hasResults":11,"nctId":127,"briefTitle":128,"officialTitle":129,"acronym":4,"eligibilityCriteria":130,"healthyVolunteers":131,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":132,"targetDuration":4,"studyType":22,"phases":134,"briefSummary":135,"conditions":136,"keywords":4,"overallStatus":95,"whyStopped":4,"lastUpdateSubmitDate":138,"lastUpdatePostDateStruct":139,"startDateStruct":141,"completionDateStruct":143,"leadSponsor":145,"locationsCount":123},"100376905","post-market-follow-up-study-on-paragon-crt-100-paflufocon-d-100376905","NCT04187599","Post-market Follow Up Study on Paragon CRT® 100 (Paflufocon D)","Post-market Follow Up Study on Paragon CRT® 100 (Paflufocon D) Rigid Gas Permeable Contact Lenses for Corneal Refractive Therapy for Temporary Myopic Refractive Power Reduction","Inclusion Criteria:\n\n1. Patient contact lens refraction should fit within the available parameters of the study lenses (spherical power within -4.00D and the cylinder power within 1.50D).\n2. Is willing to comply with the wear and visit schedule.\n3. Is willing to participate and signed the informed consent form.\n\nExclusion Criteria:\n\n1. Age under 8 years old\n2. Any ocular abnormalities, undergone corneal surgery, or history of ocular trauma, active corneal infections (corneal inflammation), corneal curvature less than 40.00D or more than 46.00D\n3. Best corrected visual acuity less than 1.0D\n4. Pregnant, lactating or near-pregnancy\n5. The eye has the following conditions:\n\n   1. Acute and subacute inflammations or infection of the anterior segment of the eye\n   2. Any eye disease, injury, or abnormality that affects the cornea, conjunctiva or eyelids, e.g. dacryocystitis, conjunctivitis, blepharitis and other inflammation, glaucoma, etc.\n   3. Severe insufficiency of tears (TBUT≤5s).\n   4. Allergy to any ingredient, such as mercury or thimerosal, in a solution which is to be used to care\n   5. Any active corneal infection (bacterial, fungal or viral).\n6. Manifested strabismus\n7. Abnormal intra-ocular pressure\n8. Suffering from systemic diseases, resulting in low immunity, or affecting corneal re-shaping (such as acute and chronic sinusitis, diabetes, Down syndrome, rheumatoid arthritis, mental patients, etc.)\n9. Under medications or long-term medications that lead to dry eye with clinical signs or affects vision and corneal curvature.\n10. Examination result indicate any contraindication or not suitable for OrthoK lens wear\n11. Participated in pharmaceutical clinical study 3 months before the date of the screening or participated any other medical devices research study within 30 days of the screening\n12. Only eye fulfills inclusion criteria\n13. History of any ocular operations\n14. Unable to follow investigator's instruction\n15. Any other condition not suitable for the study per investigator's judgement",true,{"count":133,"type":21},250,[24],"The main objective of this post market clinical study is to evaluate the effectiveness and safety of the Paragon CRT®100 Contact Lens.",[137],"Myopia","2019-12-04",{"date":140,"type":32},"2019-12-05",{"date":142,"type":32},"2019-08-29",{"date":144,"type":21},"2020-12-31",{"name":38,"class":39},""]