[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Cornell University\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":391},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,14,0,[8,40,62,91,122,142,169,193,220,254,280,301,326,361],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":4,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":30,"lastUpdatePostDateStruct":31,"startDateStruct":34,"completionDateStruct":35,"leadSponsor":37,"locationsCount":4},"100645411","the-influence-of-water-intake-on-snack-intake-in-children-100645411",false,"NCT07680647","The Influence of Water Intake on Snack Intake in Children","Investigating the Influence of Consuming Water as a Beverage on Intake of a Snack in Children","Kids Water","Inclusion Criteria:\n\n* Like, are willing to eat study food\n* Does not have allergies, food restrictions or health issues that prevent them from consuming study food\n* Will attend summer camp during both of the scheduled study visits\n\nExclusion Criteria:\n\n\\-","ALL","6 Years","12 Years",{"count":21,"type":22},50,"ESTIMATED","INTERVENTIONAL",[25],"NA","The primary purpose of this study is to investigate the influence of including water as a beverage at a snack on food intake in children.",[28],"Eating Behaviors","NOT_YET_RECRUITING","2026-06-29",{"date":32,"type":33},"2026-07-02","ACTUAL",{"date":30,"type":22},{"date":36,"type":22},"2026-09-15",{"name":38,"class":39},"Cornell University","OTHER",{"id":41,"slug":42,"hasResults":11,"nctId":43,"briefTitle":44,"officialTitle":44,"acronym":45,"eligibilityCriteria":46,"healthyVolunteers":11,"sex":17,"minAge":47,"maxAge":48,"enrollmentInfo":49,"targetDuration":4,"studyType":23,"phases":50,"briefSummary":51,"conditions":52,"keywords":4,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":53,"lastUpdatePostDateStruct":54,"startDateStruct":56,"completionDateStruct":58,"leadSponsor":60,"locationsCount":61},"100644415","the-combined-effects-of-energy-density-and-variety-on-intake-100644415","NCT07663214","The Combined Effects of Energy Density and Variety on Intake","VarxED","Inclusion Criteria:\n\n* Regularly consume 3 meals per day\n* Like, are willing to eat, and do not have allergies to the study foods\n* Are willing to refrain from drinking alcohol the day before study visits\n* Are willing to consume a consistent breakfast the day of study visits\n* Have a BMI between 18.5-29.9 kg\u002Fm2\n\nExclusion Criteria:\n\n* Experienced a weight change \\>5 kg in the past month\n* Are a smoker\n* Are an athlete in training\n* Take medications or have a health condition known to affect appetite\n* Are pregnant or breastfeeding\n* Have ever been diagnosed with an eating disorder or depression\n* Specialize in the fields of psychology or nutritional sciences.","20 Years","60 Years",{"count":21,"type":22},[25],"The primary purpose of this study is to investigate the influence independent fn combined influence of variety and energy density on food intake at a meal. Additionally, individual characteristics will be examined for their influence on the effects of variety and energy density on intake.",[28],"2026-06-17",{"date":55,"type":33},"2026-06-23",{"date":57,"type":22},"2026-07-01",{"date":59,"type":22},"2027-07-31",{"name":38,"class":39},1,{"id":63,"slug":64,"hasResults":11,"nctId":65,"briefTitle":66,"officialTitle":66,"acronym":67,"eligibilityCriteria":68,"healthyVolunteers":69,"sex":17,"minAge":70,"maxAge":71,"enrollmentInfo":72,"targetDuration":4,"studyType":23,"phases":74,"briefSummary":75,"conditions":76,"keywords":78,"overallStatus":82,"whyStopped":4,"lastUpdateSubmitDate":83,"lastUpdatePostDateStruct":84,"startDateStruct":86,"completionDateStruct":88,"leadSponsor":90,"locationsCount":61},"100633478","the-meta-shift-study-how-metabolic-shift-shapes-human-immunometabolism---a-fasting-trial-100633478","NCT07527208","The Meta-SHIFT Study: How Metabolic Shift Shapes Human Immunometabolism - a Fasting Trial","Meta-SHIFT","Inclusion Criteria:\n\n* Apparently healthy\n* Age 18-40y at the time of recruitment\n* BMI ≥ 18.5 and ≤ 24.9 kg\u002Fm2\n* Willing to participate in all study activities during the 3-day intervention\n* Signed informed consent\n\nExclusion Criteria:\n\n* Diagnosed with any chronic medical condition that can interfere with the study outcome (e.g., cardiovascular disease, cancer, diabetes mellitus type 1 or 2, liver disease, pulmonary disease, renal disease, inflammatory bowel disease, thyroid disease, long COVID, PASC)\n* Bleeding disorder (e.g., Hemophilia A\u002FB, Von Willebrand Disease, or low platelets), current anemia or current use of blood thinners or anticoagulants (e.g. warfarin, heparin)\n* Any acute or chronic infection disease or fever in the past month\n* Antibiotic use in the past 2 months\n* Use of any prescribed medications (incl. GLP-1 agonists), except for contraceptives\n* Usage of recreational drugs in the last three months\n* Unstable body weight (weight gain or loss \\>5% of total BW in the past three months)\n* Following any restrictive diet within one month of starting the study (for example a ketogenic diet or weight loss diet)\n* Fasted for 16 hours or longer in the past week\n* History of an eating disorder (e.g., anorexia nervosa, bulimia nervosa, or binge eating disorder)\n* Allergic to one or more components of the standardized meal and\u002For shake (i.e., milk, wheat, and soy)\n* Average alcohol intake that exceeds 1 consumption\u002Fday or 7 consumptions\u002Fweek over the past month\n* Tobacco smoker or regular use of nicotine products\n* Donated or intend to donate blood from 2 months before the study until the end of the study\n* Being pregnant or lactating\n* Participation in another biomedical study during this study",true,"18 Years","40 Years",{"count":73,"type":22},28,[25],"During fasting, the body shifts from using carbohydrates to relying more on fat as its main source of energy. This process is known as the 'metabolic shift'. Fat tissue helps supply this energy by breaking down stored fat into fatty acids, which are released into the bloodstream and transported to organs throughout the body. In addition to fatty acids, many other substances in the blood (such as metabolites) change during fasting to help maintain normal body function.\n\nImmune cells also circulate in the blood and play an important role in protecting the body against infections and diseases such as cancer. However, it is not yet well understood how the metabolic shift during fasting affects immune cell function. The purpose of this study is to investigate how 24 hours of fasting influences immune cell metabolism and function.",[77],"Fasting",[77,79,80,81],"PBMC","Adipose tissue","Energy metabolism","RECRUITING","2026-05-04",{"date":85,"type":33},"2026-05-07",{"date":87,"type":22},"2026-06-01",{"date":89,"type":22},"2026-12",{"name":38,"class":39},{"id":92,"slug":93,"hasResults":11,"nctId":94,"briefTitle":95,"officialTitle":96,"acronym":4,"eligibilityCriteria":97,"healthyVolunteers":69,"sex":17,"minAge":98,"maxAge":99,"enrollmentInfo":100,"targetDuration":4,"studyType":23,"phases":102,"briefSummary":104,"conditions":105,"keywords":109,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":114,"lastUpdatePostDateStruct":115,"startDateStruct":117,"completionDateStruct":119,"leadSponsor":121,"locationsCount":61},"100636483","early-phase-1-micropractices-for-unhoused-lgbtq-youth-100636483","NCT07566273","Micropractices for Unhoused LGBTQ Youth","Developing and Evaluating Collaboratively Designed Mindfulness and Identity-Affirming Practices for Unhoused LGBTQ Youth","Inclusion Criteria:\n\n* Aged 16 to 26 years\n* Self-identify as LGBTQ\n* Currently or recently experiencing housing instability (within the past six months)\n* Have access to a mobile device with internet capability to complete study activities\n\nExclusion Criteria:\n\n* Unable to complete study procedures (e.g., lack of device access)","16 Years","26 Years",{"count":101,"type":22},200,[103],"EARLY_PHASE1","In the present study, the investigators will conduct a pilot randomized controlled trial to evaluate the feasibility, acceptability, and preliminary efficacy of brief, co-designed mindfulness and identity-affirming micropractices for LGBTQ youth and young adults experiencing housing instability. Participants (n = 200, accounting for anticipated attrition) will be randomly assigned to one of two conditions: (1) a mindfulness and identity-based micropractice condition or (2) a structurally equivalent neutral control condition. The intervention content will be developed using a participatory co-design process with members of the target population and standardized prior to trial implementation. The mindfulness and identity condition integrates brief practices targeting present-moment awareness and identity affirmation, whereas the control condition accounts for time and attention without including these components. Assessments will be conducted at baseline, post-intervention, and three-month follow-up. Primary outcomes include feasibility and acceptability, assessed using standardized implementation outcome measures and indicators of intervention adherence. Secondary outcomes include changes in mental health symptoms, psychological and emotional well-being, and substance use. The investigators will evaluate whether the mindfulness and identity-based condition demonstrates greater improvements in outcomes compared to the control condition and will estimate effect sizes to inform the design of future fully powered trials. The intervention will be delivered via a mobile-accessible platform.",[106,107,108],"Well-Being (Psychological Flourishing)","Internalizing Mental Health Symptoms","Substance Abuse",[110,111,112,108,113,107],"Micropractice","Unhoused","Well-Being","LGBTQ","2026-04-29",{"date":116,"type":33},"2026-05-05",{"date":118,"type":22},"2026-10",{"date":120,"type":22},"2027-01",{"name":38,"class":39},{"id":123,"slug":124,"hasResults":11,"nctId":125,"briefTitle":126,"officialTitle":126,"acronym":127,"eligibilityCriteria":128,"healthyVolunteers":11,"sex":17,"minAge":47,"maxAge":48,"enrollmentInfo":129,"targetDuration":4,"studyType":23,"phases":131,"briefSummary":132,"conditions":133,"keywords":4,"overallStatus":82,"whyStopped":4,"lastUpdateSubmitDate":134,"lastUpdatePostDateStruct":135,"startDateStruct":137,"completionDateStruct":139,"leadSponsor":141,"locationsCount":61},"100626712","the-influence-of-water-intake-on-food-intake-at-meals-varying-in-moisture-100626712","NCT07439198","The Influence of Water Intake on Food Intake at Meals Varying in Moisture","WaterxMoisture","Inclusion Criteria:\n\n* 20 - 60 years old\n* Regularly consume 3 meals per day\n* Like, are willing to eat, and do not have restrictions or allergies to the study foods\n* Are willing to refrain from drinking alcohol the day before study visits\n* Are willing to consume a consistent breakfast the day of study visits\n* Have a BMI between 20-29.9 kg\u002Fm2\n\nExclusion Criteria:\n\n* Experienced a weight change \\>5 kg in the past month\n* Are a smoker\n* Are an athlete in training\n* Take medications or have a health condition known to affect taste, smell, thirst, or appetite\n* Are pregnant or breastfeeding\n* Have ever been diagnosed with an eating disorder or depression\n* Specialize in the fields of psychology or nutritional sciences",{"count":130,"type":22},60,[25],"The primary purpose of this study is to investigate the influence of including water as a beverage at a meal on food intake, and if the influence of water consumption on food consumption is moderated by switching behavior. Additionally, other individual characteristics will be examined for their influence on the effects of simultaneous variety and portion size on meal intake.",[28],"2026-04-21",{"date":136,"type":33},"2026-04-23",{"date":138,"type":33},"2026-03-15",{"date":140,"type":22},"2027-02-23",{"name":38,"class":39},{"id":143,"slug":144,"hasResults":11,"nctId":145,"briefTitle":146,"officialTitle":147,"acronym":4,"eligibilityCriteria":148,"healthyVolunteers":11,"sex":149,"minAge":47,"maxAge":150,"enrollmentInfo":151,"targetDuration":4,"studyType":153,"phases":4,"briefSummary":154,"conditions":155,"keywords":157,"overallStatus":82,"whyStopped":4,"lastUpdateSubmitDate":161,"lastUpdatePostDateStruct":162,"startDateStruct":164,"completionDateStruct":166,"leadSponsor":168,"locationsCount":61},"100263177","vitamin-d-dynamics-in-women-100263177","NCT02705287","Vitamin D Dynamics in Women","Vitamin D Dynamics in Pregnant Women and Non-Pregnant Women of Reproductive Age","Inclusion Criteria (Non-pregnant and pregnant participants participants):\n\n* Self-reported White and Black women\n* Age 20-39\n* Body mass index (BMI) 1or pre-pregnancy BMI (If currently pregnant) either 18.5-24.9 kg\u002Fm2 or greater than or equal to 30 kg\u002Fm2\n\nInclusion Criteria (Additional criteria for pregnant participants):\n\n* Singleton pregnancy\n* Recruited in first trimester, second trimester, or third trimester\n* No pregnancy complications\n\nExclusion Criteria (Non-pregnant and pregnant participants):\n\n* BMI or pre-pregnancy BMI \\\u003C18.5 kg\u002Fm2\n* Human immunodeficiency virus (HIV) infection\n* Diagnosed eating disorder\n* Malabsorption disease\n* Diabetes\n* Elevated diastolic blood pressure (\\>110 mm\u002FHg)\n* Steroid use\n* Substance abuse history\n* Current use of medications known to influence vitamin D or calcium homeostasis\n* Plans to travel to lower latitude during the 20-day study period\n* Plans to become pregnant during the study period (non-pregnant only)\n* Refuses to discontinue tanning bed use during study period\n* Refuses to discontinue vitamin or mineral supplement use during study period (non-pregnant only)\n\nExclusion Criteria (Additional criteria for pregnant participants):\n\n* Gestational diabetes\n* Pregnancy hypertension","FEMALE","39 Years",{"count":152,"type":22},160,"OBSERVATIONAL","The goal of this project is to utilize stable isotopically labeled vitamin D3 and state of the art mass spectrometric methodology to assess vitamin D dynamics during pregnancy in relation to relation to obesity and vitamin D binding protein genotype. At the conclusion of this study, the investigators will have obtained novel information on the absorption and utilization of vitamin D in women and the degree to which vitamin D utilization during pregnancy is impacted by genetic ancestry, vitamin D binding protein concentration and genotype and by excess adiposity. The long-term goal is to better understand the unique metabolism of vitamin D during pregnancy.",[156],"Pregnancy",[158,159,160],"vitamin D","half life","kinetics","2026-03-27",{"date":163,"type":33},"2026-04-01",{"date":165,"type":33},"2024-10-28",{"date":167,"type":22},"2029-05",{"name":38,"class":39},{"id":170,"slug":171,"hasResults":11,"nctId":172,"briefTitle":173,"officialTitle":173,"acronym":4,"eligibilityCriteria":174,"healthyVolunteers":69,"sex":17,"minAge":175,"maxAge":176,"enrollmentInfo":177,"targetDuration":4,"studyType":23,"phases":179,"briefSummary":180,"conditions":181,"keywords":4,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":185,"lastUpdatePostDateStruct":186,"startDateStruct":188,"completionDateStruct":190,"leadSponsor":192,"locationsCount":61},"100626711","impact-of-a-cricket-and-black-soldier-fly-larvae-fortified-cracker-on-the-gut-microbiome-and-iron-status-in-malagasy-schoolchildren-100626711","NCT07439185","Impact of a Cricket and Black Soldier Fly Larvae-Fortified Cracker on the Gut Microbiome and Iron Status in Malagasy Schoolchildren","Inclusion criteria for children\n\n* Child (male, female, intersex, non-binary), aged 9 to 13 years old who attends one of the selected schools\n* Caregiver or legal guardian is willing to provide informed consent\n* Child is willing to provide informed assent\n\nExclusion criteria for children\n\n* Child age is outside the preferred age range (9 to 13 years)\n* Not enrolled in the participating schools\n* Unable or unwilling to comply with the study requirements\n* Illness requiring medical treatment, malaria, severe anemia (hemoglobin (Hb) concentration below 8.0 g\u002FdL as indicated by HemoCue 201+ system), severe acute malnutrition, fever, diarrhea, etc.\n* Covid-exposure or symptoms: loss of smell or taste\n* History of food allergies or adverse reactions to any edible insects\n* Chronic severe medical condition or congenital anomalies requiring frequent medical attention or interfering with dietary consumption\n* Caregiver does not give consent, or child does not assent\n\nInclusion criteria for parents • Willing to participate in completing surveys about demographics and household dynamics (assets, housing structure, etc.)\n\nExclusion criteria for parents\n\n• Caregiver does not consent to participate","9 Years","13 Years",{"count":178,"type":22},650,[25],"The purpose of this study is to determine the health impacts of consistent consumption of insect-fortified crackers among school-aged children in Madagascar.\n\nSpecifically, in this RCT, the investigators will assess whether the insect-fortified crackers can improve the health status of Malagasy school children. The investigators' objectives are to: (1) Assess changes in gut microbiome composition that occur after 6 and 14 weeks of cracker consumption through 16S rRNA sequencing. (2) Assess changes in intestinal and systemic inflammation after 6 and 14 weeks of cracker consumption through quantification of fecal calprotectin, lactoferrin, myeloperoxidase (MPO), and alpha-1-antitrypsin (AAT) and circulating pro-inflammatory cytokines. (3) Assess changes in iron status after 14 weeks of cracker consumption through quantification of hemoglobin (Hb), inflammation-adjusted serum ferritin, and soluble transferrin receptor (sTfR).",[182,183,184],"Gut -Microbiota","Inflamation","Iron Absorption","2026-02-23",{"date":187,"type":33},"2026-02-27",{"date":189,"type":22},"2026-02",{"date":191,"type":22},"2026-06",{"name":38,"class":39},{"id":194,"slug":195,"hasResults":11,"nctId":196,"briefTitle":197,"officialTitle":198,"acronym":4,"eligibilityCriteria":199,"healthyVolunteers":69,"sex":17,"minAge":70,"maxAge":4,"enrollmentInfo":200,"targetDuration":4,"studyType":23,"phases":201,"briefSummary":202,"conditions":203,"keywords":205,"overallStatus":82,"whyStopped":4,"lastUpdateSubmitDate":212,"lastUpdatePostDateStruct":213,"startDateStruct":215,"completionDateStruct":217,"leadSponsor":219,"locationsCount":61},"100610194","a-digital-intervention-to-promote-preschool-nutrition-and-activity-the-eheros-study-100610194","NCT07224412","A Digital Intervention to Promote Preschool Nutrition and Activity: The eHEROs Study","Utilizing Digital Health Approaches to Promote Early Childhood Healthy Eating and Activity Behaviors","Inclusion Criteria:\n\n* Participants must have a preschool-aged child (3-5 years) with no disabilities or conditions that impact typical eating and activity behaviors.\n* Adult participants must have access to a smartphone, reliable internet at home, and can make video calls.\n\nExclusion Criteria:\n\n* Adults who do not have a child aged 3-5 or child has a disability\u002Fcondition that impact typical eating and activity behaviors.\n* Technology access is limited.\n* Adults who read, write or speak a language other than English.",{"count":130,"type":22},[25],"The purpose of this pilot study is to assess the feasibility and acceptability of the Know-How program, a 10-week digital intervention for families of young children promoting healthy eating and activity behaviors and environments.",[204],"Health Behavior",[206,207,208,209,210,211],"parents","child, preschool","mHealth","mobile app","nutrition","physical activity","2026-02-10",{"date":214,"type":33},"2026-02-12",{"date":216,"type":33},"2026-01-05",{"date":218,"type":22},"2027-03-30",{"name":38,"class":39},{"id":221,"slug":222,"hasResults":11,"nctId":223,"briefTitle":224,"officialTitle":225,"acronym":226,"eligibilityCriteria":227,"healthyVolunteers":69,"sex":17,"minAge":228,"maxAge":229,"enrollmentInfo":230,"targetDuration":4,"studyType":23,"phases":232,"briefSummary":233,"conditions":234,"keywords":237,"overallStatus":82,"whyStopped":4,"lastUpdateSubmitDate":246,"lastUpdatePostDateStruct":247,"startDateStruct":249,"completionDateStruct":251,"leadSponsor":253,"locationsCount":61},"100575839","the-precision-nutrition-new-york-study-100575839","NCT06777498","The Precision Nutrition New York Study","Optimizing Dietary Fiber Eating Patterns to Prevent Obesity and Resulting Metabolic Disorders","PNNY","Inclusion Criteria:\n\n* Age is between 21-50 years\n* BMI is between 25-30. You can check your BMI here: https:\u002F\u002Fwww.cdc.gov\u002Fbmi\u002Fadult-calculator\u002Findex.html\n* Must be able to have height, weight, waist, and hip circumference, and body composition measured during the study\n* Must be able to provide saliva samples.\n* Must be able to provide a phone number and email address at which the study investigators can contact for study-related matters.\n* Must be able to increase dietary fiber intake to the recommended level following the instructions on the USDA MyPlate website: https:\u002F\u002Fwww.myplate.gov\u002Fmyplate-plan\n* Must be able to provide food records of everything consumed (food, beverage, and supplements) on one weekday and one weekend day (example Tuesday, Saturday) every week during the study. This will be done using an online survey.\n* Must be able to provide 10 stool samples over 11 weeks of the study duration. 18) Must have stable weight (within ±3% of usual body weight) for the last two months.\n* Must be able to to take an online survey to assess recent dietary fiber intake to determine eligibility.\n\nExclusion Criteria:\n\n* Electronic medical implant, for example, a pacemaker.\n* An existing, UNTREATED, thyroid condition.\n* Use of systemic antibiotics (intravenous injection, intramuscular, or oral) within the last 4 months.\n* An acute disease at the time of enrollment (Acute disease is defined as the presence of a moderate or severe illness with or without fever).\n* A chronic, clinically significant (unresolved, requiring ongoing medical management or medication) pulmonary, cardiovascular, gastrointestinal, hepatic, or renal functional abnormality.\n* Any suspected state of immunosuppression or immunodeficiency including HIV.\n* A history of active UNTREATED gastrointestinal disorders or diseases including\n\n  1. Inflammatory bowel disease (IBD)\n  2. Ulcerative colitis (mild-moderate-severe)\n  3. Crohn's or celiac disease\n  4. Indeterminate colitis\n  5. Irritable bowel syndrome (IBS) (moderate-severe)\n  6. Persistent, infectious gastroenteritis, colitis or gastritis\n  7. Persistent or chronic diarrhea of unknown etiology\n  8. Clostridium difficile infection (recurrent)\n  9. Chronic constipation\n* Previously had bariatric surgery.\n* An unstable dietary history as defined by major changes in diet during the previous month. For example, elimination or significantly increased intake of a major food group in the diet.\n* Recent history of chronic alcohol consumption defined as more than 5 drinks (or servings) of alcohol per day.\n* Female participants: pregnant\u002Flactating.","21 Years","50 Years",{"count":231,"type":22},15,[25],"Dietary fiber has been shown to have beneficial effects on human health through its impact on microbes present in the gut. However, these effects can vary between individuals, and everyone may not reap the same health benefits by eating the same sources of fiber. Factors predicting how an individual's gut microbes as well as the beneficial metabolites produced by these microbes change in response to different sources of fiber would be helpful in developing precision nutrition approaches that maximize the benefits of dietary fiber. The objective of this study is to evaluate candidate predictors of gut microbiota response to fiber sources from either whole grains or fruits and vegetables.",[235,236],"Body Composition Changes","Body Weight Changes",[238,239,240,241,242,243,244,245],"dietary fiber","gut microbiome","gut microbiota","short-chain fatty acids","SCFAs","whole grains","fruits","vegetables","2025-07-09",{"date":248,"type":33},"2025-07-11",{"date":250,"type":33},"2025-01-13",{"date":252,"type":22},"2025-12-31",{"name":38,"class":39},{"id":255,"slug":256,"hasResults":11,"nctId":257,"briefTitle":258,"officialTitle":259,"acronym":4,"eligibilityCriteria":260,"healthyVolunteers":69,"sex":149,"minAge":70,"maxAge":48,"enrollmentInfo":261,"targetDuration":4,"studyType":23,"phases":263,"briefSummary":264,"conditions":265,"keywords":269,"overallStatus":82,"whyStopped":4,"lastUpdateSubmitDate":272,"lastUpdatePostDateStruct":273,"startDateStruct":275,"completionDateStruct":277,"leadSponsor":279,"locationsCount":61},"100592052","income-volatility-and-mental-health-full-experiment-100592052","NCT06988410","Income Volatility and Mental Health, Full Experiment","Unstable Income, Rising Stress? The Effect of Income Instability on Psychological and Physiological Health","Inclusion Criteria:\n\n* Between ages of 18 - 60\n* Female\n* Lives in a household with 5 or fewer adults\n\nExclusion Criteria:\n\n* Pregnancy",{"count":262,"type":22},2267,[25],"Income instability is a defining aspect of the lives of the poor, who also disproportionately suffer from poor mental and physical health. This research is the first to assess the causal effects of predictable and unpredictable income instability on the psychological and physical health of the poor. It will advance the scientific knowledge on the effects of economic instability as well as understanding of health gaps across populations.",[266,267,268],"Depression","Anxiety","Blood Pressure",[270,271],"income instability","uncertainty","2025-05-27",{"date":274,"type":33},"2025-05-31",{"date":276,"type":33},"2025-04-17",{"date":278,"type":22},"2025-10-12",{"name":38,"class":39},{"id":281,"slug":282,"hasResults":11,"nctId":283,"briefTitle":284,"officialTitle":284,"acronym":285,"eligibilityCriteria":286,"healthyVolunteers":69,"sex":17,"minAge":70,"maxAge":71,"enrollmentInfo":287,"targetDuration":4,"studyType":153,"phases":4,"briefSummary":289,"conditions":290,"keywords":4,"overallStatus":82,"whyStopped":4,"lastUpdateSubmitDate":293,"lastUpdatePostDateStruct":294,"startDateStruct":296,"completionDateStruct":298,"leadSponsor":300,"locationsCount":61},"100527349","heme-and-non-heme-iron-intakes-gut-microbiota-and-influence-on-host-iron-absorption-100527349","NCT06146608","Heme and Non-heme Iron Intakes, Gut Microbiota, and Influence on Host Iron Absorption","FeMicrobiome","Inclusion Criteria:\n\n* Healthy adults\n* Age between 18- 40y\n* Non-smoking\n* Not currently taking vitamin, mineral, prebiotic, and probiotic supplements.\n* Females: premenopausal and not pregnant or lactating\n* No preexisting medical complications (such as eating disorders, hemoglobinopathies, malabsorption diseases, steroid use, substance abuse history, or taking medications known to influence iron homeostasis)\n* Body mass index (BMI) between 18 - 27 kg\u002Fm2.\n\nExclusion Criteria:\n\n* BMI \\\u003C18 or \\> 27 kg\u002Fm2,\n* Age \\\u003C18 y or \\> 40y,\n* Smoking\n* Pregnancy, lactating\n* Have gastrointestinal disorders\u002Fmalabsorption diseases\u002Fhemoglobinopathies\u002Fdietary restrictions\u002Fsteroid use\u002F medication use of medications known to impact iron status, iron utilization or inflammatory status\n* Currently take vitamin, mineral, prebiotic, and probiotic supplements.\n* Recently received antibiotic treatment",{"count":288,"type":22},120,"The FeMicrobiome study will evaluate gut microbiome features and their relationships with dietary iron absorption in healthy adults. The investigators hypothesize that (1) the gut microbiota can be shaped by the heme and non-heme Fe content of the diet and that (2) this will influence individual variation in dietary Fe absorption.",[291,292],"Anemia, Iron Deficiency","Iron Overload","2025-02-21",{"date":295,"type":33},"2025-02-24",{"date":297,"type":33},"2023-01-15",{"date":299,"type":22},"2026-01-14",{"name":38,"class":39},{"id":302,"slug":303,"hasResults":11,"nctId":304,"briefTitle":305,"officialTitle":306,"acronym":307,"eligibilityCriteria":308,"healthyVolunteers":69,"sex":17,"minAge":4,"maxAge":4,"enrollmentInfo":309,"targetDuration":4,"studyType":23,"phases":310,"briefSummary":311,"conditions":312,"keywords":315,"overallStatus":82,"whyStopped":4,"lastUpdateSubmitDate":319,"lastUpdatePostDateStruct":320,"startDateStruct":322,"completionDateStruct":324,"leadSponsor":325,"locationsCount":61},"100558997","advanced-cooking-education-full-scale-study-100558997","NCT06558396","Advanced Cooking Education Full Scale Study","Advanced Cooking Education (ACE) 4-H After School Club Full Scale Study","ACE","Inclusion Criteria:\n\n* 7th and 8th grade students attending Title I funded schools in New York City\n* Caregivers of the 7th and 8th grade students attending Title I funded schools in New York City\n\nExclusion Criteria:\n\n* Do not speak\u002Funderstand English\n* Those who have previously participated in the Virtual ACE program (Feasibility Study), or In-Person ACE Pilot Study",{"count":101,"type":22},[25],"The aim of this study is to assess the impact of an in-person multi-component Advanced Cooking Education (ACE) 4-H after school program. The ACE Program consists of mindfulness, nutrition education, cooking labs, and professional development activities.",[313,314],"Adolescent Behavior","Nutrition, Healthy",[316,317,318],"Adolescents","Nutrition intervention","Culinary programs","2024-08-14",{"date":321,"type":33},"2024-08-16",{"date":323,"type":33},"2023-11-01",{"date":118,"type":22},{"name":38,"class":39},{"id":327,"slug":328,"hasResults":11,"nctId":329,"briefTitle":330,"officialTitle":331,"acronym":332,"eligibilityCriteria":333,"healthyVolunteers":11,"sex":149,"minAge":19,"maxAge":70,"enrollmentInfo":334,"targetDuration":4,"studyType":23,"phases":335,"briefSummary":336,"conditions":337,"keywords":350,"overallStatus":82,"whyStopped":4,"lastUpdateSubmitDate":319,"lastUpdatePostDateStruct":355,"startDateStruct":356,"completionDateStruct":358,"leadSponsor":360,"locationsCount":61},"100558914","in-person-lifestyle-program-for-black-adolescent-girls-at-risk-for-type-2-diabetes-100558914","NCT06557317","In-Person Lifestyle Program for Black Adolescent Girls at Risk for Type 2 Diabetes","Examining the Preliminary Efficacy of an In-Person Lifestyle Intervention for Black Female Adolescent\u002FCaregiver Dyads at Risk for Type 2 Diabetes Mellitus","BGW In-Person","Inclusion Criteria for adolescent participants:\n\n* 12-18 years of age\n* self-identify as Black or African American\n* have obesity (\\>=95th percentile BMI)\n\nExclusion Criteria for adolescent participants:\n\n* pregnant or within 3 months postpartum.\n* participated in a formal weight management program within 6 months prior to study.\n* currently taking medications or diagnosed with a condition known to influence metabolism, physical activity ability, or cognitive function.\n* have previously undergone bariatric surgery.\n* have type 2 diabetes.\n* unable to speak English or have developmental conditions that interfere with ability to communicate.\n\nInclusion Criteria for caregiver participants:\n\n* 18 years or older.\n* proficiency in speaking English.\n* live in the same household as the adolescent who will also be enrolled.\n* prepares the majority (\\>50%) of meals in the household.\n\nExclusion Criteria for caregiver participants:\n\n* pregnant or within 3 months postpartum.\n* unable to speak English or have developmental conditions that interfere with ability to communicate.",{"count":130,"type":22},[25],"The aim of this study is to look at changes in diabetes-related risk factors in Black adolescent girls who are at risk for type 2 diabetes and their primary female caregiver after both participating in a 12-week in-person lifestyle program.",[338,339,340,341,342,343,344,345,346,347,348,349],"Behavior, Adolescent","Childhood Obesity","Diabetes Mellitus, Type 2","Pediatric Obesity","Glucose Metabolism Disorders","Metabolic Disease","Endocrine System Diseases","Overweight","Overnutrition","Nutrition Disorders","Body Weight","Diabetes Mellitus",[316,351,352,353,354],"In-Person Lifestyle Program","Diabetes prevention","Black girls","Obesity",{"date":321,"type":33},{"date":357,"type":22},"2024-08",{"date":359,"type":22},"2024-12-31",{"name":38,"class":39},{"id":362,"slug":363,"hasResults":11,"nctId":364,"briefTitle":365,"officialTitle":366,"acronym":367,"eligibilityCriteria":368,"healthyVolunteers":69,"sex":149,"minAge":175,"maxAge":369,"enrollmentInfo":370,"targetDuration":4,"studyType":153,"phases":4,"briefSummary":371,"conditions":372,"keywords":376,"overallStatus":82,"whyStopped":4,"lastUpdateSubmitDate":382,"lastUpdatePostDateStruct":383,"startDateStruct":385,"completionDateStruct":387,"leadSponsor":389,"locationsCount":390},"100395092","ovarian-morphology-in-girls-100395092","NCT04424576","Ovarian Morphology in Girls","Trajectory of Ovarian Morphology During the Adolescent Reproductive Transition","OMG","Inclusion Criteria:\n\n* Female adolescents aged 9 to 17 years\n* Menarche within 11 months of the enrollment visit\n* University of Rochester site only: Family history of PCOS (i.e., mother or aunt)\n\nExclusion Criteria:\n\n* Current or recent use of medications or supplements known or suspected to interfere with reproductive or metabolic function in the past 2 months (e.g., contraceptives, metformin, steroids, anti-seizure medications)\n* Untreated and\u002For unstable medical or mental health condition known or suspected to interfere with reproductive or metabolic function\n* Currently pregnant or breast feeding\n* History of ovarian surgery\n* Presence of significant acute or chronic illness which may interfere with study participation","17 Years",{"count":130,"type":22},"Establishment of regular menstrual cycles is a key component of reproductive maturation and a recognized vital sign for health and well-being. Irregular menstrual cycles are especially common for the first 2-3 years after an adolescent's first menstrual period (i.e., menarche), which delays the identification and diagnosis of early reproductive disturbances such as polycystic ovary syndrome (PCOS). The purpose of this research study is to determine whether the ovary can serve as a reliable predictor of normal or abnormal development by following the trajectory of ovarian morphology in conjunction with menstrual cyclicity using 3D transabdominal ultrasound imaging in a prospective cohort study of adolescents. A secondary objective is to identify potential environmental factors such as diet and the gut microbiome which influence the trajectory towards normal or abnormal reproductive development.",[373,374,375],"Amenorrhea","Oligomenorrhea","Puberty",[377,378,379,380,381],"Ovary","Transabdominal Ultrasound","Menarche","Periods","Microbiome","2024-08-08",{"date":384,"type":33},"2024-08-12",{"date":386,"type":33},"2020-01-31",{"date":388,"type":22},"2025-03-31",{"name":38,"class":39},3,""]