[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Cukurova University\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":647},{"pageToken":4,"total":5,"offset":6,"count":7,"results":8},null,37,0,25,[9,52,78,103,128,157,186,214,238,261,280,304,326,352,380,408,430,462,488,512,535,556,577,602,624],{"id":10,"slug":11,"hasResults":12,"nctId":13,"briefTitle":14,"officialTitle":15,"acronym":4,"eligibilityCriteria":16,"healthyVolunteers":12,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":33,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":40,"lastUpdatePostDateStruct":41,"startDateStruct":44,"completionDateStruct":46,"leadSponsor":48,"locationsCount":51},"100611543","external-oblique-intercostal-block-eoicb-for-laparoscopic-cholecystectomy-100611543",false,"NCT07241949","External Oblique Intercostal Block (EOICB) for Laparoscopic Cholecystectomy","Paravertebral Block or External Oblique Intercostal Block? A Comparative Analysis of Pain and Opioid Consumption After Laparoscopic Cholecystectomy: A Randomized Controlled Trial","Inclusion Criteria:\n\n* Age between 18 and 65 years\n* Scheduled for elective laparoscopic cholecystectomy under general anesthesia\n* ASA physical status I-III\n* Able to understand the study procedure and provide informed consent\n\nExclusion Criteria:\n\nPatient refusal or inability to provide informed consent\n\nAllergy or contraindication to local anesthetics, tramadol, or study medications\n\nCoagulopathy or current anticoagulant therapy\n\nLocal infection at the planned block injection site\n\nSevere hepatic or renal impairment\n\nChronic opioid use or opioid dependence\n\nNeurological or psychiatric disorders affecting pain perception or communication\n\nPregnancy or breastfeeding\n\nBody mass index (BMI) \\> 35 kg\u002Fm²\n\nConversion to open cholecystectomy during surgery","ALL","18 Years","65 Years",{"count":21,"type":22},147,"ESTIMATED","INTERVENTIONAL",[25],"NA","This single-center, prospective, randomized controlled trial aims to compare the effects of paravertebral block (PVB), external oblique intercostal (EOI) block, and intravenous patient-controlled analgesia (PCA) with tramadol on postoperative pain and opioid consumption in patients undergoing elective laparoscopic cholecystectomy. The primary endpoint is total tramadol consumption within 24 hours postoperatively. Secondary outcomes include pain scores, additional analgesic use, incidence of nausea\u002Fvomiting, mobilization time, and length of hospital stay.",[28,29,30,31,32],"Postoperative Pain","Laparoscopic Cholecystectomy","Paravertebral Block","External Oblique Intercostal Plane Block","Patient Controlled Analgesia",[34,35,36,37,38],"Cholecystectomy","Pain","Analgesia","Tramadol","Nerve Block","RECRUITING","2026-06-30",{"date":42,"type":43},"2026-07-02","ACTUAL",{"date":45,"type":43},"2025-12-01",{"date":47,"type":22},"2026-12-05",{"name":49,"class":50},"Cukurova University","OTHER",1,{"id":53,"slug":54,"hasResults":12,"nctId":55,"briefTitle":56,"officialTitle":57,"acronym":58,"eligibilityCriteria":59,"healthyVolunteers":12,"sex":17,"minAge":18,"maxAge":60,"enrollmentInfo":61,"targetDuration":4,"studyType":23,"phases":63,"briefSummary":64,"conditions":65,"keywords":67,"overallStatus":69,"whyStopped":4,"lastUpdateSubmitDate":70,"lastUpdatePostDateStruct":71,"startDateStruct":73,"completionDateStruct":75,"leadSponsor":77,"locationsCount":4},"100644488","recovery-analgesia-and-delirium-profiles-at-laparoscopic-surgeries-with-processed-eeg-monitoring-100644488","NCT07670689","Recovery, Analgesia And Delirium Profiles At Laparoscopic Surgeries With Processed EEG Monitoring","Recovery, Analgesia And Delirium Profiles At Laparoscopic Surgeries With Processed EEG Monitoring: Comparison Of Trendelenburg And Reverse-Trendelenburg Positions","T and RT","Inclusion Criteria:\n\n* adult patients aged 18-75 yr, classified as American Society of Anesthesiologists (ASA) physical status I-II, and scheduled for elective laparoscopic abdominal surgery with an anticipated duration of at least 1 h\n\nExclusion Criteria:\n\n* if they had a history of neuropsychiatric disorders, neuromuscular disease, severe cardiovascular or respiratory disease, upper respiratory tract infection within the preceding 14 days, body mass index (BMI) \\>40 kg m-², alcohol or substance abuse, previous bronchospasm, anticipated difficult tracheal intubation, previous tracheostomy, laryngeal disease or surgery, ASA physical status ≥III, or an actual surgical duration of less than 1 h","75 Years",{"count":62,"type":22},136,[25],"The aim of this study is to evaluate the effects of processed electroencephalogram (pEEG) monitoring on recovery and extubation times, length of stay in the post-anesthesia care unit (PACU), postoperative pain, patient comfort, sedation, development of delirium, and length of hospital and intensive care unit stay in laparoscopic surgeries performed in the Trendelenburg (T) or reverse Trendelenburg (RT) positions.\n\nMaterials and Methods: This prospective, randomized, single-center study included a total of 136 patients will be scheduled for elective laparoscopic surgery under general anesthesia. Patients will allocated into four groups according to surgical position (Group T or Group RT) and the use of processed electroencephalogram monitoring (Group TBIS and Group RTBIS). Intraoperative depth of anesthesia will be maintained either by titration guided by processed electroencephalogram indices or according to standard clinical parameters. Extubation time, recovery time, length of stay in the PACU, postoperative pain scores, patient comfort, level of sedation, incidence of delirium, and lengths of hospital and intensive care unit stay will be recorded.",[66],"Elective Laparoscopic Abdominal Surgery",[68],"Processed EEG; Laparoscopic surgery; Trendelenburg position; Reverse Trendelenburg; Recovery; Delirium; Depth of anesthesia","NOT_YET_RECRUITING","2026-06-22",{"date":72,"type":43},"2026-06-26",{"date":74,"type":22},"2026-07-27",{"date":76,"type":22},"2027-01-15",{"name":49,"class":50},{"id":79,"slug":80,"hasResults":12,"nctId":81,"briefTitle":82,"officialTitle":83,"acronym":4,"eligibilityCriteria":84,"healthyVolunteers":12,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":85,"targetDuration":4,"studyType":23,"phases":87,"briefSummary":89,"conditions":90,"keywords":92,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":95,"lastUpdatePostDateStruct":96,"startDateStruct":98,"completionDateStruct":100,"leadSponsor":102,"locationsCount":51},"100644266","phase-4-the-effect-of-neostigmine-and-sugammadex-on-the-optic-nerve-sheath-diameter-100644266","NCT07666984","The Effect of Neostigmine and Sugammadex on the Optic Nerve Sheath Diameter","Comparison of the Effects of Neostigmine and Sugammadex on the Optic Nerve Sheath Diameter During the Postoperative Extubation Period","Inclusion Criteria:\n\n* With an ASA physical status of 1-2\n* Patients scheduled for elective surgery\n* Patients willing to participate in the study\n\nExclusion Criteria:\n\n* Patients with heart, liver, kidney, or respiratory failure\n* Brain tumors, hemorrhages, or aneurysms\n* Patients who have undergone eye, cardiovascular, or neurosurgery\n* Eye or neurological diseases or increased intracranial pressure\n* Laparoscopic surgeries\n* Cases not in the supine position\n* Allergy to the medications used\n* Patients who did not provide informed consent to participate in the study.",{"count":86,"type":22},86,[88],"PHASE4","This study will compare how two drugs, sugammadex and neostigmine-used to reverse muscle relaxation after surgery-affect the size of the optic nerve sheath (the nerve behind the eye) as patients wake up and have their breathing tubes removed. It will also examine the relationship between changes in blood pressure and heart rate during this time and these measurements. This study will be conducted on 86 healthy patients aged 18-65 who will undergo planned surgery at the Çukurova University Faculty of Medicine, Department of Anesthesiology and Reanimation. Patients will be randomly divided into two groups: the sugammadex group and the neostigmine group. All patients will receive standard general anesthesia and rocuronium to relax their muscles. At the end of the surgery, to reverse this effect, patients will be given either sugammadex or a mix of neostigmine and atropine. Group S will receive 2 mg sugammadex per kg, while Group N will receive 0.05 mg neostigmine and 0.02 mg atropine per kg. The width of the optic nerve sheath will be measured by ultrasound 5 minutes after the breathing tube is inserted, 5 minutes before the tube is removed, and 5 minutes after it is removed. Additionally, blood pressure, heart rate, and any complications during the surgery will be tracked and compared between the groups.",[91],"Neuromuscular Blockade Reversal Agent",[93,94],"Neuromuscular Blockade reversal agent","Optic nerve sheath diameter","2026-06-19",{"date":97,"type":43},"2026-06-24",{"date":99,"type":43},"2026-06-04",{"date":101,"type":22},"2026-07-10",{"name":49,"class":50},{"id":104,"slug":105,"hasResults":12,"nctId":106,"briefTitle":107,"officialTitle":108,"acronym":109,"eligibilityCriteria":110,"healthyVolunteers":12,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":111,"targetDuration":4,"studyType":23,"phases":113,"briefSummary":114,"conditions":115,"keywords":118,"overallStatus":69,"whyStopped":4,"lastUpdateSubmitDate":120,"lastUpdatePostDateStruct":121,"startDateStruct":123,"completionDateStruct":125,"leadSponsor":127,"locationsCount":51},"100642929","evaluation-of-different-non-invasive-methods-in-the-treatment-of-dentin-hypersensitivity-associated-with-non-carious-cervical-lesions-a-split-mouth-clinical-study-100642929","NCT07648147","Evaluation of Different Non-Invasive Methods in the Treatment of Dentin Hypersensitivity Associated With Non-Carious Cervical Lesions: A Split-Mouth Clinical Study","EVALUATION OF DIFFERENT NON-INVASIVE METHODS IN THE TREATMENT OF DENTIN HYPERSENSITIVITY ASSOCIATED WITH NON-CARIOUS CERVICAL LESIONS: A SPLIT-MOUTH CLINICAL STUDY","NCCL-DH","Inclusion Criteria:\n\n* Individuals aged between 18 and 65 years. Systemically healthy individuals. Individuals with dentin hypersensitivity. Presence of two permanent teeth with similar severity of dentin hypersensitivity in the same participant.\n\nParticipants who agree to participate in the study and sign the informed consent form\n\nExclusion Criteria:\n\n* Presence of active caries in the study teeth. Presence of cervical restoration in the study teeth. Presence of pulpal pathology. History of desensitizing treatment within the last 3 months. Pregnancy. Presence of systemic disease. Use of analgesics within the last 48 hours.",{"count":112,"type":22},30,[25],"The aim of this split-mouth clinical study is to compare the effectiveness of D Blue diode laser application and ProSylc bioactive glass powder application in reducing dentin hypersensitivity in patients with non-carious cervical lesions (NCCLs). Different treatment modalities will be applied within the same participant, and changes in dentin hypersensitivity will be evaluated following treatment. The primary outcome measure will be the reduction in dentin hypersensitivity after the interventions. The findings of this study are expected to contribute to the identification of effective non-invasive treatment approaches for the management of dentin hypersensitivity associated with non-carious cervical lesions.",[116,117],"Non-Carious Cervical Lesions (NCCLs)","Dentin Hypersensitivity",[119],"Non-Carious Cervical Lesions; Dentin Hypersensitivity; Diode Laser; D Blue Diode Laser; Bioactive Glass; ProSylc; Split-Mouth Study; Non-Invasive Treatment","2026-06-10",{"date":122,"type":43},"2026-06-15",{"date":124,"type":22},"2026-07-20",{"date":126,"type":22},"2027-01-20",{"name":49,"class":50},{"id":129,"slug":130,"hasResults":12,"nctId":131,"briefTitle":132,"officialTitle":133,"acronym":134,"eligibilityCriteria":135,"healthyVolunteers":12,"sex":136,"minAge":18,"maxAge":4,"enrollmentInfo":137,"targetDuration":139,"studyType":140,"phases":4,"briefSummary":141,"conditions":142,"keywords":145,"overallStatus":69,"whyStopped":4,"lastUpdateSubmitDate":149,"lastUpdatePostDateStruct":150,"startDateStruct":152,"completionDateStruct":154,"leadSponsor":156,"locationsCount":51},"100638221","comparison-of-sentinel-lymph-node-applications-in-endometrial-cancer-cases-performed-with-vaginal-natural-orifice-transluminal-endoscopic-surgery-v-notes-and-conventional-laparoscopy-100638221","NCT07583329","Comparison of Sentinel Lymph Node Applications in Endometrial Cancer Cases Performed With Vaginal Natural Orifice Transluminal Endoscopic Surgery (V-NOTES) and Conventional Laparoscopy","Comparison of Sentinel Lymph Node Applications in Endometrial Cancer Cases Performed With V-NOTES and Conventional Laparoscopy: A Multicenter Prospective Observational Study","V-COSMOS","Inclusion Criteria:\n\n* Age ≥18 years\n* Histologically confirmed endometrial cancer on preoperative endometrial biopsy\n* Disease confirmed to be confined to the uterus based on clinical evaluation and imaging\n* No evidence of lymphatic or distant metastasis on positron emission tomography\u002Fcomputed tomography(PET\u002FCT) or magnetic resonance imaging (MRI)\n* Surgical staging with sentinel lymph node biopsy recommended by a multidisciplinary tumor board\n* Surgical treatment performed using either conventional laparoscopy or the vNOTES approach\n\nExclusion Criteria:\n\n* Presence of extrauterine disease\n* Detection of distant metastasis\n* Surgery performed via an open (laparotomy) approach\n* Incomplete medical records\n* History of prior pelvic radiotherapy","FEMALE",{"count":138,"type":22},160,"10 Years","OBSERVATIONAL","Endometrial cancer is a common cancer in women, and surgery is usually the first step in treatment. During surgery, doctors often check nearby lymph nodes to see if the cancer has spread. A newer method called sentinel lymph node (SLN) mapping allows doctors to examine only the first few lymph nodes most likely to contain cancer. This can reduce the need for removing many lymph nodes and may lower the risk of complications.\n\nMinimally invasive surgery is commonly performed using small abdominal incisions (laparoscopy). A newer technique, called vaginal natural orifice transluminal endoscopic surgery (vNOTES), allows the surgery to be performed through the vagina without any cuts on the abdomen. This approach may lead to less pain, quicker recovery, and no visible scars.\n\nThis study will compare these two surgical methods-laparoscopy and vNOTES-in patients with early-stage endometrial cancer. Researchers will look at how safe and effective each method is, how patients recover after surgery, and how well the sentinel lymph node procedure works with each technique. The study will also examine how quickly surgeons become experienced with the newer vNOTES method.\n\nThe goal of this research is to determine whether vNOTES can be a safe and effective alternative to standard laparoscopic surgery, while offering potential benefits for patients.",[143,144],"Endometrial Adenocarcinoma","Endometrial Cancer",[146,147,148],"v-notes","sentinel lymph node","conventional laparoscopy","2026-05-18",{"date":151,"type":43},"2026-05-20",{"date":153,"type":22},"2026-05-19",{"date":155,"type":22},"2036-04-30",{"name":49,"class":50},{"id":158,"slug":159,"hasResults":12,"nctId":160,"briefTitle":161,"officialTitle":162,"acronym":4,"eligibilityCriteria":163,"healthyVolunteers":12,"sex":17,"minAge":164,"maxAge":165,"enrollmentInfo":166,"targetDuration":4,"studyType":23,"phases":168,"briefSummary":169,"conditions":170,"keywords":175,"overallStatus":69,"whyStopped":4,"lastUpdateSubmitDate":178,"lastUpdatePostDateStruct":179,"startDateStruct":181,"completionDateStruct":182,"leadSponsor":184,"locationsCount":185},"100639102","empowering-families-in-pediatric-cardiovascular-surgery-a-ram-based-approach-100639102","NCT07575451","Empowering Families in Pediatric Cardiovascular Surgery: A RAM-Based Approach","Evaluation of a Nursing Program Based on Roy's Adaptation Model for Empowering Families of Children Aged 1 to 3 Years Post-Cardiac Surgery","Inclusion Criteria:\n\n* Families who agree to participate in the study and sign the informed consent form.\n* Families of children aged 1-3 years in the preoperative period who are scheduled to undergo cardiac surgery due to congenital heart disease.\n* Families who do not speak or read Turkish but will undergo cardiac surgery due to congenital heart disease will also be included in the study with the assistance of an interpreter.\n* Families who are over 18 years of age and have access to a mobile phone or internet at home.\n\nExclusion Criteria:\n\n* Exclusion criteria include the presence of additional congenital malformations, dysmorphic syndromes, chromosomal or endocrine disorders, severe infection, hypothyroidism, or any similar conditions that could lead to growth and developmental delay in the child, alongside congenital heart disease","1 Year","3 Years",{"count":167,"type":22},80,[25],"The purpose of this clinical trial is to learn about the effects of a nursing support program designed for families of children aged 1 to 3 years who have undergone heart surgery. This program aims to improve parents' caregiving skills and support the healthy growth of their children.\n\nThe primary questions the study aims to answer are:\n\nDoes the nursing program positively affect the physical growth of children, such as their height and weight?\n\nDoes the program improve children's scores on general development tests (Denver II)?\n\nDo parents' attitudes toward child feeding and their confidence in parenting skills increase?\n\nResearchers will divide participants into two groups:\n\nExperimental Group: Families who participate in the nursing education program and receive an informative booklet.\n\nControl Group: Families who only receive an informative booklet and continue with routine hospital follow-ups.\n\nThe researchers will compare these two groups to see if participating in the nursing program leads to better results for the children's development and the families' skills.\n\nParticipants will be asked to:\n\nAttend 5 different education and counseling sessions, starting one week before surgery and continuing until the child reaches 1 year of follow-up.\n\nMeet with the researcher at specific intervals (at 1, 2, 3, 6, 9, and 12 months) for one year to monitor the child's development (height, weight, head circumference) and skills.\n\nComplete surveys regarding child feeding attitudes and parenting skills at the 6th and 12th month follow-ups.",[171,172,173,174],"Congenital Heart Disease","Postoperative Care","Child Development","Roy Adaptation Model-based Nursing Empowerment Program",[171,176,172,177],"Cardiac Surgery","Nursing Support Program","2026-05-08",{"date":180,"type":43},"2026-05-12",{"date":122,"type":22},{"date":183,"type":22},"2027-06-15",{"name":49,"class":50},3,{"id":187,"slug":188,"hasResults":12,"nctId":189,"briefTitle":190,"officialTitle":191,"acronym":4,"eligibilityCriteria":192,"healthyVolunteers":12,"sex":17,"minAge":18,"maxAge":193,"enrollmentInfo":194,"targetDuration":4,"studyType":23,"phases":196,"briefSummary":197,"conditions":198,"keywords":200,"overallStatus":69,"whyStopped":4,"lastUpdateSubmitDate":206,"lastUpdatePostDateStruct":207,"startDateStruct":209,"completionDateStruct":211,"leadSponsor":213,"locationsCount":51},"100636624","adductor-canal-block-with-or-without-biceps-femoris-short-head-block-in-total-knee-arthroplasty-100636624","NCT07568106","Adductor Canal Block With or Without Biceps Femoris Short Head Block in Total Knee Arthroplasty","Effect of Adding a Biceps Femoris Short Head Block to an Adductor Canal Block on Postoperative Pain and Functional Outcomes After Total Knee Arthroplasty: A Randomized Controlled Trial","Inclusion Criteria:\n\n* ASA I-III\n* Adult patients undergoing unilateral primary TKA\n* Planned spinal anesthesia\n* Written informed consent\n\nExclusion Criteria:\n\n* Coagulopathy\n* Drug allergy\n* BMI \\> 35\n* Renal\u002Fhepatic failure\n* Chronic pain or opioid use\n* Depression or psychiatric disorder\n* Revision or bilateral TKA\n* Neurological deficits\n* Preoperative ROM \\\u003C 90°","80 Years",{"count":195,"type":22},132,[25],"Total knee arthroplasty is associated with moderate to severe postoperative pain, which may delay mobilization and recovery. Multimodal analgesia including regional anesthesia techniques is widely used to improve outcomes. The adductor canal block (ACB) provides anteromedial knee analgesia but may not adequately cover the posterolateral region.\n\nThe biceps femoris short head (BiFeS) block is a novel motor-sparing regional anesthesia technique targeting the posterolateral capsule of the knee. This randomized controlled trial aims to compare the analgesic efficacy and functional outcomes of ACB combined with BiFeS block versus ACB alone in patients undergoing total knee arthroplasty.\n\nThe primary outcome is posterior knee pain at postoperative 6 hours. Secondary outcomes include pain scores within 48 hours, opioid consumption, early and late functional recovery, and opioid-related adverse effects.",[199],"Total Knee Arthroplasty",[199,201,202,28,203,204,205],"Adductor Canal Block","Biceps Femoris Short Head Block","Functional Recovery","Opioid Consumption","Knee Osteoarthritis","2026-04-29",{"date":208,"type":43},"2026-05-05",{"date":210,"type":22},"2026-05-15",{"date":212,"type":22},"2027-02-15",{"name":49,"class":50},{"id":215,"slug":216,"hasResults":12,"nctId":217,"briefTitle":218,"officialTitle":219,"acronym":4,"eligibilityCriteria":220,"healthyVolunteers":12,"sex":17,"minAge":221,"maxAge":222,"enrollmentInfo":223,"targetDuration":4,"studyType":23,"phases":225,"briefSummary":226,"conditions":227,"keywords":4,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":230,"lastUpdatePostDateStruct":231,"startDateStruct":233,"completionDateStruct":235,"leadSponsor":237,"locationsCount":51},"100597456","different-hemostatic-agents-used-in-partial-pulpotomy-on-pulp-survival-and-postoperative-pain-100597456","NCT07058727","Different Hemostatic Agents Used in Partial Pulpotomy on Pulp Survival and Postoperative Pain","The Effect of Different Hemostatic Agents Used in Partial Pulpotomy on Pulp Survival and Postoperative Pain: A Randomized Clinical Trial","Inclusion Criteria:\n\n* Permanent teeth with carious pulp exposure (no spontaneous pain).\n* Positive vitality test (Endo-Ice).\n* No periapical radiolucency.\n\nExclusion Criteria:\n\n* Systemic diseases affecting healing.\n* Pregnancy.\n* Non-vital pulp\u002Fnecrosis","15 Years","55 Years",{"count":224,"type":22},75,[25],"This randomized clinical trial evaluates the efficacy of sodium hypochlorite (NaOCl), chlorhexidine (CHX), and cold saline as hemostatic agents in partial pulpotomy. The study compares postoperative pain (via VAS scores) and pulp survival (via clinical\u002Fradiographic evaluation) at 1, 3, 7 days, 6 months, and 12 months",[228,229,28],"Efficacy of Hemostatic Agents","Partial Pulpotomy","2026-03-27",{"date":232,"type":43},"2026-04-01",{"date":234,"type":43},"2025-05-01",{"date":236,"type":22},"2026-05-01",{"name":49,"class":50},{"id":239,"slug":240,"hasResults":12,"nctId":241,"briefTitle":242,"officialTitle":243,"acronym":4,"eligibilityCriteria":244,"healthyVolunteers":245,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":246,"targetDuration":4,"studyType":23,"phases":248,"briefSummary":249,"conditions":250,"keywords":4,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":230,"lastUpdatePostDateStruct":254,"startDateStruct":256,"completionDateStruct":258,"leadSponsor":260,"locationsCount":51},"100595392","comparison-of-clinical-performance-of-partial-restorations-fabricated-with-three-dimensional-printer-and-cad-cam-100595392","NCT07031856","Comparison of Clinical Performance of Partial Restorations Fabricated With Three-Dimensional Printer and CAD-CAM","Comparison of Clinical Performance of Partial Restorations Fabricated With Three-Dimensional Printer and CAD-CAM: A Split-Mouth Randomized Clinical Trial","İncluiding:\n\n\\-- Patients with periodontally stable and appropriate oral hygiene habits without serious systemic diseases that preclude restoration. - Male and female patients with hard tissue loss in their mouth or with 2 teeth in need of restoration replacement (eligibility for split-mouth design). - People who can comply with the treatment and volunteer for follow-up for 2 years-\n\nExclusion Criteria:\n\nPatients with systemic conditions that may affect the study process (e.g. diabetes, autoimmune diseases).\n\n* Patients with excessive bruxism or parafunctional habits.\n* Pregnant or lactating women.\n* Patients with gum disease or severe bone loss.\n* Patients with a history of allergic reactions.",true,{"count":247,"type":22},12,[25],"The aim of this clinical study is to compare CAD-CAM and 3D restorations in individuals with two hard tissue losses or restorations in their mouths. The main question it aims to answer is: Is there a difference between CAD-CAM and 3D restorations according to FDI criteria? Researchers will compare participants to see if there is a difference between the two restorations according to FDI criteria. In this split-mouth study, participants will be randomized to receive a CAD-CAM partial restoration on one tooth and a 3D partial restoration on the other tooth.",[251,252,253],"Dental Caries","Dental Restoration, Permanent","Tooth Diseases",{"date":255,"type":43},"2026-04-02",{"date":257,"type":43},"2025-07-01",{"date":259,"type":22},"2026-11",{"name":49,"class":50},{"id":262,"slug":263,"hasResults":12,"nctId":264,"briefTitle":265,"officialTitle":265,"acronym":4,"eligibilityCriteria":266,"healthyVolunteers":12,"sex":17,"minAge":221,"maxAge":222,"enrollmentInfo":267,"targetDuration":4,"studyType":23,"phases":269,"briefSummary":270,"conditions":271,"keywords":4,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":230,"lastUpdatePostDateStruct":274,"startDateStruct":276,"completionDateStruct":277,"leadSponsor":279,"locationsCount":51},"100596165","effects-of-total-and-selective-caries-removal---requiring-or-avoiding-vital-pulp-therapy---on-pulp-vitality-and-postoperative-pain-in-deep-carious-mature-permanent-teeth-a-split-mouth-clinical-study-100596165","NCT07041905","Effects of Total and Selective Caries Removal - Requiring or Avoiding Vital Pulp Therapy - on Pulp Vitality and Postoperative Pain in Deep Carious Mature Permanent Teeth: A Split-Mouth Clinical Study","Inclusion Criteria:\n\n* Patients aged ≥15 years with bilateral deep carious mature permanent teeth.\n* Positive vitality test (cold sensitivity).\n* No spontaneous pain or periapical radiolucency.\n* Willingness to attend 6- and 12-month follow-ups\n\nExclusion Criteria:\n\n* Uncontrolled systemic diseases Pregnancy or allergy to dental materials used Teeth with irreversible pulpitis (spontaneous pain, necrosis) Non-restorable teeth (fractures, extensive decay)",{"count":268,"type":22},15,[25],"The effect of selective caries cleaning and total caries cleaning on pulp health and post operative pain in teeth with deep caries will be investigated.",[272,273],"Pulp Exposure, Dental","Deep Dental Caries",{"date":275,"type":43},"2026-03-30",{"date":257,"type":43},{"date":278,"type":22},"2026-08-01",{"name":49,"class":50},{"id":281,"slug":282,"hasResults":12,"nctId":283,"briefTitle":284,"officialTitle":284,"acronym":4,"eligibilityCriteria":285,"healthyVolunteers":245,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":286,"targetDuration":4,"studyType":23,"phases":288,"briefSummary":289,"conditions":290,"keywords":4,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":296,"lastUpdatePostDateStruct":297,"startDateStruct":298,"completionDateStruct":300,"leadSponsor":302,"locationsCount":303},"100612078","the-effect-of-a-transtheoretical-model-based-educational-intervention-on-first-year-nursing-students-hpv-knowledge-health-beliefs-and-vaccination-behavior-intentions-100612078","NCT07248904","The Effect of a Transtheoretical Model-Based Educational Intervention on First-Year Nursing Students' HPV Knowledge, Health Beliefs, and Vaccination Behavior Intentions","Inclusion Criteria:\n\n* First-year students enrolled in the Nursing Department of the Faculty of Health Sciences\n* Provide written informed consent to participate\n* Agree to attend all educational sessions and data collection appointments during the study period\n* Have sufficient Turkish literacy to read and understand study materials\n* Have not previously received any comprehensive education about HPV infection or HPV vaccination\n\nExclusion Criteria:\n\n* Students who do not agree to participate in the study\n* Students who do not provide written informed consent",{"count":287,"type":22},88,[25],"The purpose of this study is to examine the impact of a structured educational program based on the Transtheoretical Model (TTM) on HPV knowledge, health beliefs, and vaccination behavioral intentions among first-year nursing students. The study will also evaluate how the intervention affects students' HPV vaccine readiness compared to the TTM.\n\nThe primary questions addressed by the study are:\n\n* Does the TTM-based educational intervention increase students' knowledge about HPV and the HPV vaccine?\n* Does the program change students' health beliefs regarding susceptibility, severity, benefits, and barriers to HPV and the HPV vaccine?\n* Does the program improve students' intentions and readiness to receive the HPV vaccine?\n* Do students move to a higher behavioral readiness stage (from Precontemplation to Contemplation, Preparation, Action, or Maintenance) after the intervention?\n\nThe researcher will compare the TTM-based educational intervention with a control group that did not receive structured education to determine whether a personalized, stage-based approach is more effective in improving HPV-related outcomes among nursing students.\n\nParticipants will:\n\n* Complete baseline questionnaires measuring HPV knowledge, health beliefs, and vaccination intention.\n* The experimental group (intervention group) will receive personalized TTM-based education, face-to-face instruction in modules aligned with the five TTM phases (Precontemplation, Contemplation, Preparation, Action, and Maintenance).\n* The experimental group will participate in educational sessions designed to raise awareness, correct misinformation, support decision-making, and encourage protective behaviors.\n* The control group will not receive any educational program.\n* All participants in the experimental and control groups will complete the same questionnaires again to assess changes after the intervention.\n\nThe TTM-based educational intervention provides:\n\n* Staged counseling\n* Information about HPV and the HPV vaccine\n* Activities to raise awareness, strengthen motivation, and support vaccination adoption\n* Personalized feedback based on student readiness\n* Structured modules focusing on knowledge, belief, and behavior change strategies\n\nThe study population included first-year nursing students enrolled in the Faculty of Health Sciences. A total of 88 participants will be recruited and randomly assigned to either the intervention (n=44) or control (n=44) groups through simple randomization.\n\nThe results of this study are expected to contribute to the development of evidence-based education strategies in nursing, support of behavioral change models in health education, and strengthen the role of future nurses in HPV prevention, vaccine advocacy, and public health practice.",[291,292,293,294,295],"Human Papillomavirus (HPV)","Papillomavirus Vaccines","Health Knowledge, Attitudes, Practice","Students, Nursing","Health Behavior","2026-03-26",{"date":230,"type":43},{"date":299,"type":43},"2026-01-16",{"date":301,"type":22},"2026-04-30",{"name":49,"class":50},2,{"id":305,"slug":306,"hasResults":12,"nctId":307,"briefTitle":308,"officialTitle":309,"acronym":4,"eligibilityCriteria":310,"healthyVolunteers":245,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":311,"targetDuration":4,"studyType":23,"phases":313,"briefSummary":314,"conditions":315,"keywords":4,"overallStatus":69,"whyStopped":4,"lastUpdateSubmitDate":319,"lastUpdatePostDateStruct":320,"startDateStruct":322,"completionDateStruct":323,"leadSponsor":325,"locationsCount":4},"100628669","objectve-structured-clncal-examnaton-stress-for-intravenous-perpheral-catheterzaton-100628669","NCT07464652","Objectıve Structured Clınıcal Examınatıon Stress For Intravenous Perıpheral Catheterızatıon","Investıgatıon Of The Effect Of Intravenous Peripheral Catheterızatıon Objectıve Structured Clınıcal Examınatıon Applıcatıon On The Stress And Skıll Levels Of Nursıng Students","Inclusion Criteria:\n\n* The students are enrolled in the Fundamentals of Nursing II course for the first time, will be experiencing OSCE for the first time, and have volunteered to participate in the research.\n\nExclusion Criteria:\n\n* The reasons for the students' disqualification include their graduation from a vocational health high school or their studies in a health-related field, their lack of prior experience in basic nursing skills, their failure to participate in laboratory work conducted as part of the course, and their incomplete completion of tests.",{"count":312,"type":22},52,[25],"In this planned study, the stress levels of nursing students regarding intravenous access during the OSCE (Objective Structured Clinical Examination) will be measured using self-report questionnaires and smartwatches. Stress levels will be compared with those of another student group who did not undergo the OSCE assessment but performed intravenous access procedures.",[316,317,318],"OSCE (Objective Structured Clinical Examination)","Stress","Nursing Education","2026-03-06",{"date":321,"type":43},"2026-03-11",{"date":151,"type":22},{"date":324,"type":22},"2026-12-20",{"name":49,"class":50},{"id":327,"slug":328,"hasResults":12,"nctId":329,"briefTitle":330,"officialTitle":330,"acronym":331,"eligibilityCriteria":332,"healthyVolunteers":12,"sex":136,"minAge":4,"maxAge":4,"enrollmentInfo":333,"targetDuration":334,"studyType":140,"phases":4,"briefSummary":335,"conditions":336,"keywords":340,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":344,"lastUpdatePostDateStruct":345,"startDateStruct":347,"completionDateStruct":349,"leadSponsor":351,"locationsCount":51},"100622213","the-effect-of-dose-and-storage-conditions-of-indocyanine-green-on-efficacy-and-cost-in-sentinel-lymph-node-mapping-in-gynecological-cancer-100622213","NCT07380698","The Effect of Dose and Storage Conditions of Indocyanine Green on Efficacy and Cost in Sentinel Lymph Node Mapping in Gynecological Cancer","DOSTCONICG","Inclusion Criteria:\n\n* cervical cancer, endometrial cancer, vulvar cancer, using indocyanine green, sentinel lymph node dissection\n\nExclusion Criteria:\n\n\\-",{"count":112,"type":22},"1 Month","This research will determine the impact of optimizing dosage and storage conditions for indocyanine green on health outcomes and will contribute to improving treatment processes in gynecological cancers. Ultrastaging will increase the detection of micrometastases. Furthermore, the cost impact of these optimizations will be evaluated. It will help develop more effective, safe, and cost-effective methods for sentinel lymph node mapping in gynecological cancers. Furthermore, significant savings in healthcare costs could be achieved.",[144,337,338,339],"Vulvar Cancers","Cervical Cancer","Indocyanine Green (ICG)",[341,342,343],"endometrial cancer","vulvar cancers","cervical cancers","2026-01-23",{"date":346,"type":43},"2026-02-02",{"date":348,"type":43},"2025-10-03",{"date":350,"type":22},"2026-09-03",{"name":49,"class":50},{"id":353,"slug":354,"hasResults":12,"nctId":355,"briefTitle":356,"officialTitle":356,"acronym":357,"eligibilityCriteria":358,"healthyVolunteers":245,"sex":136,"minAge":4,"maxAge":4,"enrollmentInfo":359,"targetDuration":4,"studyType":23,"phases":361,"briefSummary":362,"conditions":363,"keywords":368,"overallStatus":69,"whyStopped":4,"lastUpdateSubmitDate":299,"lastUpdatePostDateStruct":374,"startDateStruct":376,"completionDateStruct":378,"leadSponsor":379,"locationsCount":51},"100619581","determining-the-effect-of-midwife-led-safe-infant-care-training-for-pregnant-women-on-awareness-of-sudden-infant-death-syndrome-and-home-accidents-100619581","NCT07346482","Determining the Effect of Midwife-Led Safe Infant Care Training for Pregnant Women on Awareness of Sudden Infant Death Syndrome and Home Accidents","Infant Care","Inclusion Criteria:\n\n* Volunteering to participate in the research\n* Being able to speak and understand Turkish\n* Being literate\n* Being a primiparous pregnant woman (due to the greater need for information) ≥36th week of pregnancy (because it is close to delivery and there is sufficient time to translate what they have learned into behavior)\n\nExclusion Criteria:\n\n* Diagnosed high-risk pregnancy\n* Diagnosed mental health condition\n* Having previously received training\u002Fcourse in safe infant care",{"count":360,"type":22},120,[25],"This project is a pioneering study in determining the impact of midwife-led safe infant care training for pregnant women on awareness of sudden infant death syndrome (SIDS) and home accidents. Raising awareness and improving women's knowledge about SIDS and home accidents is expected to help reduce preventable infant deaths. If the effectiveness of this training is proven, integrating it into prenatal care programs would be a significant step towards improving maternal and child health.",[364,357,365,366,367],"Infant Death","Midwifery","Education","Accident at Home",[369,370,371,372,373],"infant","infant death","midwifery care","accident","education",{"date":375,"type":43},"2026-01-20",{"date":377,"type":22},"2026-02-16",{"date":126,"type":22},{"name":49,"class":50},{"id":381,"slug":382,"hasResults":12,"nctId":383,"briefTitle":384,"officialTitle":385,"acronym":4,"eligibilityCriteria":386,"healthyVolunteers":12,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":387,"targetDuration":4,"studyType":23,"phases":389,"briefSummary":390,"conditions":391,"keywords":393,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":400,"lastUpdatePostDateStruct":401,"startDateStruct":403,"completionDateStruct":405,"leadSponsor":407,"locationsCount":51},"100602167","effect-of-stress-ball-applied-during-surgical-debridementdressing-on-pain-distress-and-physiological-parameters-in-patients-with-diabetic-foot-ulcers-100602167","NCT07119983","Effect of Stress Ball Applied During Surgical Debridement\u002FDressing on Pain, Distress, and Physiological Parameters in Patients With Diabetic Foot Ulcers","Effect of Stress Ball Applied During Surgical Debridement\u002FDressing on Pain, Distress, and Physiological Parameters in Patients With Diabetic Foot Ulcers: A Randomized Controlled Trial","Inclusion Criteria:\n\n* Patients who agree to participate in the study and sign the Informed Consent\n* Form will be included in the study.\n* They are over 18 years of age,\n* They are literate in Turkish,\n* They are undergoing surgical debridement for the first time,\n* They are receiving inpatient treatment in the ward, and\n* They have pain ≥1 on the Visual Analog Scale (VAS) before the procedure.\n\nExclusion Criteria:\n\n* Patients who have a diagnosed psychiatric or mental illness,\n* Regular painkiller use and chronic pain,\n* Visual, hearing, perception, or communication problems,\n* Physically impaired (such as an open wound on the hand or lack of muscle strength to squeeze a stress ball),\n* Decided to undergo an intervention to reduce pain before debridement (such as local anesthesia, nerve blockade, opioid analgesics, etc.),\n* Used non-pharmacological methods to reduce pain before the procedure will not be included in the study.",{"count":388,"type":22},84,[25],"Diabetes mellitus (DM) is a common metabolic disease characterized by hyperglycemia, resulting from a deficiency or insufficiency of insulin. Diabetic foot ulcers (DFU), a late complication of diabetes, develop as a result of peripheral neuropathy, peripheral arterial disease, and trauma, negatively impacting individuals' quality of life and increasing the rate of hospitalization and amputation. While sharp debridement, one of the most effective methods in the management of diabetic foot ulcers, accelerates healing, it often causes pain and anxiety, which negatively impacts the treatment process. The physiological effects of anxiety include increased respiratory and heart rates, increased blood pressure, and prolonged procedure times. These effects can reduce patient compliance and complicate nursing care.\n\nNon-pharmacological interventions offer important alternatives for pain and anxiety management. One such method, the use of a stress ball, is based on a distraction technique and is used to reduce individuals' emotional and physiological stress levels. The literature has demonstrated the positive effects of stress balls during endoscopy, biopsy, and skin procedures. However, there is insufficient evidence regarding the use of stress balls during sharp debridement. Therefore, this study aimed to evaluate the effects of stress balls on pain, distress, and physiological parameters during surgical debridement in patients with diabetic foot ulcers. The results of this study are expected to contribute to nursing care.",[392],"Diabetic Foot Ulcer Associated With Type II Diabetes Mellitus",[394,395,396,397,398,399],"Diabetic foot ulcer","sharp debridement","pain","anxiety","stress ball","nursing care","2025-11-26",{"date":402,"type":43},"2025-12-04",{"date":404,"type":43},"2025-11-01",{"date":406,"type":22},"2026-07-01",{"name":49,"class":50},{"id":409,"slug":410,"hasResults":12,"nctId":411,"briefTitle":412,"officialTitle":413,"acronym":4,"eligibilityCriteria":414,"healthyVolunteers":12,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":415,"targetDuration":4,"studyType":23,"phases":417,"briefSummary":418,"conditions":419,"keywords":421,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":400,"lastUpdatePostDateStruct":425,"startDateStruct":426,"completionDateStruct":427,"leadSponsor":429,"locationsCount":51},"100601708","effects-of-virtual-reality-application-on-pain-anxiety-and-patient-satisfaction-in-dressing-patients-with-pressure-sores-100601708","NCT07114003","Effects of Virtual Reality Application on Pain, Anxiety, and Patient Satisfaction in Dressing Patients With Pressure Sores","Effects of Virtual Reality Application on Pain, Anxiety, and Patient Satisfaction in Dressing Patients With Pressure Sores: A Randomized Controlled Trial","Inclusion Criteria:\n\n* Participants will be individuals aged 18 and over (inclusive), who have no hearing\u002Fvisual impairment, do not have epilepsy, vertigo, or claustrophobia, and who agree to participate in the study.\n\nExclusion Criteria:\n\n* Patients who exhibit symptoms of cybersickness (dizziness, nausea, etc.) due to the VR application, who require analgesia during the intervention, or who do not feel pain due to neuropathy, and who express their wish to withdraw from the study will be excluded from the study.",{"count":416,"type":22},62,[25],"Pressure ulcers are serious and costly wounds that typically develop as a result of impaired blood flow in tissues exposed to prolonged pressure. They are particularly at risk in the elderly, critically ill patients, and individuals with limited mobility. Pain and anxiety during dressing applications for pressure ulcers can negatively impact patient comfort and compliance. There are limited studies in the literature on the use of nonpharmacological methods to reduce pain and anxiety during the dressing process for pressure ulcers. Virtual reality (VR) applications stand out as an effective method for managing pain and anxiety by providing distraction. However, existing studies generally cover all chronic wounds and lack specific research on the use of VR during the dressing process in individuals with pressure ulcers. Therefore, the proposed study aims to examine the effects of VR application during dressing on pain, anxiety, and patient satisfaction in patients with pressure ulcers and aims to make an original contribution to the literature.",[420],"Pressure Wounds",[422,35,423,424],"Virtual Reality","Anxiety","Patient Satisfaction",{"date":402,"type":43},{"date":404,"type":43},{"date":428,"type":22},"2026-06-01",{"name":49,"class":50},{"id":431,"slug":432,"hasResults":12,"nctId":433,"briefTitle":434,"officialTitle":435,"acronym":436,"eligibilityCriteria":437,"healthyVolunteers":245,"sex":136,"minAge":438,"maxAge":439,"enrollmentInfo":440,"targetDuration":4,"studyType":23,"phases":442,"briefSummary":443,"conditions":444,"keywords":446,"overallStatus":69,"whyStopped":4,"lastUpdateSubmitDate":455,"lastUpdatePostDateStruct":456,"startDateStruct":458,"completionDateStruct":459,"leadSponsor":461,"locationsCount":51},"100608902","the-effect-of-gamification-based-instructional-design-developed-100608902","NCT07207590","The Effect of Gamification-Based Instructional Design Developed","The Effect of Gamification-Based Instructional Design Developed for Postpartum Hemorrhage Management on Knowledge Acquisition and Retention","PPH-GamEd","Inclusion Criteria:\n\n* Volunteer to participate in the study\n* Must be a 4th-year midwifery student\n* Must know how to use a scanner\n* Must have successfully completed all courses on normal and risky pregnancies and normal and risky births\n\nExclusion Criteria:\n\n* Having received any prior training on postpartum hemorrhage management","17 Years","25 Years",{"count":441,"type":22},150,[25],"Turkish)\n\nAbstract:\n\nPurpose: Considering the importance of postpartum hemorrhage management in reducing preventable maternal deaths and the key role midwives play in providing this care, it is important to increase the knowledge and skills of midwifery students in this area. Many educational curricula offer weekly or semester-long courses. The Ministry also provides post-graduation training. However, considering the rates and causes of maternal deaths, it is thought that there are limitations regarding the retention of this topic. Studies on gamification in different fields and topics demonstrate its positive impact on knowledge retention. The research aims to examine the impact of a technology-based educational intervention using gamification to support midwifery students' learning and retention of knowledge on postpartum hemorrhage management.\n\nMaterials and Methods: The research will be conducted as a randomized controlled experimental study. The research population will consist of all students enrolled in the Midwifery Program in the 2024-2026 academic year, and the sample will consist of 4th-year Midwifery undergraduate students. The study sample will consist of all students in their fourth year and have completed their course registration during the 2024-2026 academic year, following the finalization of the educational content.\n\nSingle-blind, stratified randomization will be employed to prevent selection bias. A pretest, posttest, and post-study retention test will be administered during the intervention phase of the study. After data collection, the control group will receive topic review and case analysis through gamification.\n\nAfter a detailed literature review for the study, educational materials will be planned per the Ministry of Health's Postpartum Care and Emergency Obstetric Care guidelines, with identical topic content for the experimental and control groups. The experimental and control groups will receive a PowerPoint presentation on postpartum hemorrhage management, prepared by the researcher, during the first week. One week later, the experimental group will receive topic review and case analysis using a web-based gamification application on postpartum hemorrhage management, developed by the researcher and the game developer. Students in the control group will receive topic review and case analysis using traditional classroom learning techniques. Expert opinions will be sought to evaluate the content created for the experimental and control groups. The pilot group will implement the content created based on expert opinions. After the pilot application, the game and educational content will be finalized based on expert opinions.\n\nA pretest will be administered before the training, a posttest after the training and gamification application, and a retention test 3 months after the intervention. The pretest will be administered before the gamification experience and the training, the posttest after the gamification experience and the traditional method, and a retention test 3 months after the training. Data will be collected using an introductory information form and the Postpartum Hemorrhage Knowledge Test.\n\nData obtained from the study will be analyzed in a computer environment using TAP 6 and SPSS (Statistical Package for Social Sciences\u002F25.0 for Windows). The study's independent variable is the gamification teaching activity developed for postpartum hemorrhage management. The dependent variable is the students' descriptive characteristics and their knowledge level about postpartum hemorrhage management. Data will be analyzed using appropriate analysis methods after performing normality tests. Contribution to Science: Using innovative learning styles to improve the quality of education has recently become popular. As new generations grow up in the constantly evolving age of technology, old, classical methods are considered inadequate. Therefore, the plan is to use a web application developed using gamification. This new trend is innovative and technology-infused, entertaining and teaching, and avoids boring and monotonous narratives. This web application aims to help midwifery students learn postpartum hemorrhage management more memorably, enhancing their knowledge and problem-solving skills. While studies on this topic are only beginning to increase in the health field, they are limited in midwifery. Considering the importance of midwives, who play a key role in postpartum hemorrhage management and provide this care in reducing preventable maternal deaths, it is crucial to increase midwifery students' knowledge and skills in this area. A new, affordable, accessible method will be developed to achieve this most effectively. This method will provide equal educational opportunities to students who teach in different cities with varying equipment levels.",[445],"Midwifery Student",[447,448,449,450,366,451,452,453,454],"Postpartum hemorrhage","Midwife","Learning","Motivation","Student","Gamification","Game","Web application","2025-09-26",{"date":457,"type":43},"2025-10-06",{"date":45,"type":22},{"date":460,"type":22},"2026-09-01",{"name":49,"class":50},{"id":463,"slug":464,"hasResults":12,"nctId":465,"briefTitle":466,"officialTitle":466,"acronym":4,"eligibilityCriteria":467,"healthyVolunteers":12,"sex":17,"minAge":18,"maxAge":468,"enrollmentInfo":469,"targetDuration":4,"studyType":23,"phases":471,"briefSummary":472,"conditions":473,"keywords":476,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":481,"lastUpdatePostDateStruct":482,"startDateStruct":484,"completionDateStruct":486,"leadSponsor":487,"locationsCount":51},"100585712","the-effect-of-the-training-program-given-to-permanent-colostomy-patients-on-self-efficacy-100585712","NCT06905925","The Effect of the Training Program Given to Permanent Colostomy Patients on Self-efficacy","Inclusion Criteria:\n\n* • Patients scheduled for permanent colostomy following colorectal surgery,\n\n  * Aged 18 years and older,\n  * Conscious, with orientation to person, time, and place,\n  * Able to speak Turkish,\n  * Without auditory or visual impairments,\n  * Using a phone, were included in the study. Exclusion Criteria:• Patients who could not be contacted during the study period, or those who developed post-operative complications (such as stenosis, necrosis, ileus, dermatitis, parastomal herniation, etc.) were excluded from the sample.","100 Years",{"count":470,"type":22},70,[25],"The planned research aims to evaluate the impact of a training program on self-efficacy in patients with permanent colostomies. It highlights the importance of holistic patient education in preventing complications and improving adaptation to stomas, which can positively affect patients' quality of life and self-efficacy.",[474,475],"Stoma Colostomy","Colo-rectal Cancer",[477,478,479,480],"stoma","Colo-rectal cancer","consulting","self-efficacy","2025-09-07",{"date":483,"type":43},"2025-09-12",{"date":485,"type":43},"2025-06-23",{"date":428,"type":22},{"name":49,"class":50},{"id":489,"slug":490,"hasResults":12,"nctId":491,"briefTitle":492,"officialTitle":492,"acronym":4,"eligibilityCriteria":493,"healthyVolunteers":12,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":494,"targetDuration":4,"studyType":23,"phases":495,"briefSummary":496,"conditions":497,"keywords":500,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":504,"lastUpdatePostDateStruct":505,"startDateStruct":507,"completionDateStruct":509,"leadSponsor":511,"locationsCount":51},"100603486","the-effect-of-heating-the-intensive-care-room-in-the-early-postoperative-period-on-patient-outcomes-100603486","NCT07137143","The Effect of Heating the Intensive Care Room in the Early Postoperative Period on Patient Outcomes","Inclusion Criteria:\n\n* The following criteria will be included in the sample:\n* Patients who underwent elective abdominal surgery and were admitted to intensive care after surgery.\n* Patients aged 18 and over.\n* Patients whose body temperature on the morning of surgery was neither below 36°C nor above 37.5°C.\n* Patients who did not have a pacemaker, dementia, advanced spasticity, muscle atrophy, peripheral lesions, osteoporosis, skin irritation, diabetes, hypertension, or obesity.\n* Patients who did not require mechanical ventilation.\n* Patients who did not have any illness that would impair thermoregulation (such as head trauma or hypothalamic damage).\n\n  • Patients who were not taking medications that would affect thermoregulation, such as vasodilators.\n* Patients who did not have peripheral circulation problems.\n* Patients who were not alcohol or substance abusers.\n* Patients who did not have mental retardation.\n* Patients who were conscious and oriented to person, time, and place.\n* Patients who could speak Turkish.\n* Patients who did not have any auditory or visual impairments.\n* Patients who volunteered for the study.\n\nExclusion Criteria:\n\n* Patients who do not meet the sampling criteria, who develop postoperative complications (bleeding, intubation, stenosis, necrosis, ileus, dermatitis, parastomal herniation, etc.), and whose relatives do not consent to the study will not be included in the study.",{"count":470,"type":22},[25],"The aim of this study was to evaluate the effect of heating the intensive care room in the early postoperative period on patient outcomes.",[498,499],"Abdominal Surgery Complications","Hypothermia Following Anesthesia",[501,502,503],"intensive care unit","hypothermia","postoperative warming","2025-08-26",{"date":506,"type":43},"2025-08-27",{"date":508,"type":43},"2025-04-20",{"date":510,"type":22},"2025-10-30",{"name":49,"class":50},{"id":513,"slug":514,"hasResults":12,"nctId":515,"briefTitle":516,"officialTitle":516,"acronym":4,"eligibilityCriteria":517,"healthyVolunteers":12,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":518,"targetDuration":4,"studyType":23,"phases":519,"briefSummary":520,"conditions":521,"keywords":523,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":504,"lastUpdatePostDateStruct":528,"startDateStruct":530,"completionDateStruct":532,"leadSponsor":534,"locationsCount":51},"100603484","the-effect-of-tele-counseling-service-on-nutrition-exercise-attitude-and-medication-adherence-after-bariatric-surgery-100603484","NCT07137117","The Effect of Tele-Counseling Service on Nutrition, Exercise Attitude, and Medication Adherence After Bariatric Surgery","Inclusion Criteria:\n\n* Patients who have undergone laparoscopic bariatric surgery (sleeve gastrectomy only) for the first time,\n* Are between the ages of 18 and 65,\n* Are conscious and oriented to person, time, and place,\n* Can speak Turkish,\n* Have no auditory or visual impairments,\n* Can use a telephone will be included in the study.\n\nExclusion Criteria:\n\n* Patients who developed early postoperative complications (bleeding, anastomotic leakage, etc.), were hospitalized for revision surgery, and did not consent to the study will not be included in the study.",{"count":167,"type":22},[25],"The aim of this study was to evaluate the effects of teleconsultation service on nutrition, exercise attitudes and medication adherence after bariatric surgery.",[522],"Bariatric Surgery (Sleeve Gastrectomy )",[524,525,526,527],"bariatric surgery","teleconsulting","medication compliance","nutrition exercise attitude",{"date":529,"type":43},"2025-09-03",{"date":531,"type":43},"2025-04-15",{"date":533,"type":22},"2026-05-30",{"name":49,"class":50},{"id":536,"slug":537,"hasResults":12,"nctId":538,"briefTitle":539,"officialTitle":540,"acronym":541,"eligibilityCriteria":542,"healthyVolunteers":12,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":543,"targetDuration":4,"studyType":23,"phases":545,"briefSummary":546,"conditions":547,"keywords":4,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":549,"lastUpdatePostDateStruct":550,"startDateStruct":552,"completionDateStruct":554,"leadSponsor":555,"locationsCount":51},"100584078","phase-4-effect-of-mannitol-on-propofol-level-100584078","NCT06884657","Effect of Mannitol on Propofol Level","Propofol Level at TCI During Mannitol","level","Inclusion Criteria:\n\n* American Society of Anesthesiologist (ASA) II participants\n* supratentorial tumor surgery\n* eligible for mannitol use\n* eligible for Total intravenous anesthesia (TIVA)\n\nExclusion Criteria:\n\n* American Society of Anesthesiologist (ASA) III and upper\n* Chronic kidney failure\n* sepsis\n* multiorgan failure",{"count":544,"type":22},40,[88],"Group 1 will include 20 patients aged 18 years and over, American Society of Anesthesiologist (ASA) II-III class, who will undergo supratentorial tumor surgery, and Group 2 will include 20 patients who will undergo pituitary surgery without mannitol. Total intravenous anesthesia (TIVA) will be adjusted to propofol 4 µg\u002Fdl and remifentanil 2-4 µg\u002Fdl with target-controlled infusion pumps. In the mannitol group, 2.5 ml\u002Fkg (0.5 g\u002Fkg) will be given to all patients 20 minutes after induction and the mannitol infusion will be adjusted to be 10 minutes.In Group 2, mannitol will not be used and 2.5 ml\u002Fkg isotonic will be administered in 10 minutes. Both blood and urine samples will take for measurement to propofol levels.",[548],"Mannitol Adverse Reaction","2025-08-25",{"date":551,"type":43},"2025-09-02",{"date":553,"type":43},"2025-03-20",{"date":510,"type":22},{"name":49,"class":50},{"id":557,"slug":558,"hasResults":12,"nctId":559,"briefTitle":560,"officialTitle":560,"acronym":4,"eligibilityCriteria":561,"healthyVolunteers":245,"sex":136,"minAge":18,"maxAge":60,"enrollmentInfo":562,"targetDuration":4,"studyType":23,"phases":564,"briefSummary":565,"conditions":566,"keywords":4,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":569,"lastUpdatePostDateStruct":570,"startDateStruct":572,"completionDateStruct":574,"leadSponsor":576,"locationsCount":51},"100602483","the-effect-of-a-micro-appreciation-intervention-three-things-journal-application-on-caregiver-burden-family-functioning-and-happiness-levels-for-mothers-of-children-with-autism-spectrum-disorder-100602483","NCT07124091","The Effect of a Micro-Appreciation Intervention (Three-Things Journal Application) on Caregiver Burden, Family Functioning, and Happiness Levels for Mothers of Children With Autism Spectrum Disorder","Inclusion Criteria\n\n* Age 18 years or older\n* Willing to participate in the study\n* Able to read and understand Turkish\n* Being a mother of a child with special needs\n\nExclusion Criteria:\n\n* Younger than 18 years\n* Unwilling to participate in the study\n* Unable to read or understand Turkish\n* Not having a child with special needs",{"count":563,"type":22},126,[25],"Autism Spectrum Disorder (ASD) is a neurodevelopmental disorder in which individuals experience significant difficulties in social interaction, communication, and repetitive behaviors. Families of children with ASD, especially mothers, face a high level of physical, emotional, and psychological caregiving burden while trying to adapt to their children's developmental needs. Constant caregiving responsibilities increase the risk of burnout, stress, and depression in mothers, while also negatively impacting family functioning and life satisfaction. Mothers of children with ASD require greater emotional resilience, self-regulation, and social support than those in traditional parenting roles.\n\nIn this context, interventions that support psychological well-being offer important strategies that can help mothers cope with the burden of care. In recent years, positive psychology-based interventions have been shown to positively contribute to individuals' mental health and are effective in increasing subjective well-being. Positive psychology approaches help individuals recognize and focus on the positive aspects of their lives, reducing stress levels and increasing psychological resilience. One such approach, micro-appreciation interventions, aims to increase individuals' positive emotional experiences by consciously focusing on small but significant positive events they encounter in their daily lives. Micro-appreciation interventions change individuals' perceptual frameworks, encouraging them to focus on positive moments instead of negative experiences. Such interventions stand out as an effective method for reducing the psychological and physiological effects of stress, increasing positive emotions, and improving overall life satisfaction.\n\nOne micro-appreciation intervention, the \"Three Things Journal,\" is a simple yet effective strategy that involves individuals writing down three positive events they appreciate in their lives each day. Research has shown that this practice is effective in increasing individuals' awareness of positive experiences, reducing levels of depression and anxiety, and increasing subjective well-being. Regularly experiencing positive emotions strengthens individuals' ability to cope with challenges and increases their psychological resilience and optimism. Especially for individuals under intense stress, such small but regular practices can yield greater psychological benefits in the long term.",[567,568],"Autism Spectrum Disorder","Parental Stress","2025-08-12",{"date":571,"type":43},"2025-08-15",{"date":573,"type":43},"2025-05-30",{"date":575,"type":22},"2025-08-30",{"name":49,"class":50},{"id":578,"slug":579,"hasResults":12,"nctId":580,"briefTitle":581,"officialTitle":582,"acronym":4,"eligibilityCriteria":583,"healthyVolunteers":12,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":584,"targetDuration":4,"studyType":23,"phases":585,"briefSummary":586,"conditions":587,"keywords":589,"overallStatus":69,"whyStopped":4,"lastUpdateSubmitDate":594,"lastUpdatePostDateStruct":595,"startDateStruct":597,"completionDateStruct":599,"leadSponsor":601,"locationsCount":4},"100602169","partial-pulpotomy-vs-selective-removing-in-deep-caries-100602169","NCT07120009","Partial Pulpotomy vs Selective Removing in Deep Caries","Selective Caries Removal Versus Partial Pulpotomy in the Treatment of Deep Caries: A Randomized Controlled Trial","Inclusion Criteria:\n\n* Individuals aged 18-65\n* ASA I or II general health status\n* Deep primary or secondary caries lesion (up to 75% dentin thickness)\n* Restorable permanent teeth with mature apex\n* Teeth without clinical and radiographic periapical pathology\n\nExclusion Criteria:\n\n* Pregnancy\n* Periapical lesion\n* Spontaneous pain or tenderness to palpation\n* Teeth for which pulp opening or crown\u002Froot supported prosthesis is planned\n* Localized severe periodontitis",{"count":470,"type":22},[25],"The aim of this study was to compare the one-year results of selective caries removal and partial pulpotomy treatments in terms of pulp survival and the need for further endodontic treatment in deep carious lesions.Individuals aged 18-65 years with medically healthy mature permanent teeth with deep caries will be included. The included teeth will be randomly assigned to the selective caries removal or partial pulpotomy group. Follow-up evaluations will be performed at 6 months and 12 months. The main outcome is pulp survival as determined by clinical and radiographic success.",[588],"Deep Dentin Caries in Mature Permanent Teeth",[590,591,592,593],"Vital pulp therapy","Deep caries","Selective caries removal","Partial pulpotomy","2025-08-08",{"date":596,"type":43},"2025-08-13",{"date":598,"type":22},"2025-09-01",{"date":600,"type":22},"2026-12-01",{"name":49,"class":50},{"id":603,"slug":604,"hasResults":12,"nctId":605,"briefTitle":606,"officialTitle":607,"acronym":608,"eligibilityCriteria":609,"healthyVolunteers":245,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":610,"targetDuration":4,"studyType":23,"phases":611,"briefSummary":612,"conditions":613,"keywords":4,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":616,"lastUpdatePostDateStruct":617,"startDateStruct":619,"completionDateStruct":621,"leadSponsor":623,"locationsCount":51},"100598362","hand-massage-for-physical-restraint-100598362","NCT07070505","Hand Massage for Physical Restraint","Effect of Hand Massage on Physical Restraint Complications","Complications","Inclusion Criteria:\n\n* Both physical and chemical restraint must be applied, a written request for restraint must be given by the physician, both upper extremities must be restrained, and verbal permission must be obtained from the relatives.\n\nExclusion Criteria:\n\n\\-",{"count":138,"type":22},[25],"In this study, nurses will apply hand massage to patients who are physically restrained. It will be examined whether massage has a positive effect on patients' skin color, blood circulation, skin temperature and pain. Physical restraint will be applied to patients only in the presence of medical indications and with the decision of a physician.\n\nResearch question: Does hand massage applied to patients in physical restraint have an effect on preventing complications related to restraint?",[614,615],"Physical Restraints","Hand Massage","2025-07-16",{"date":618,"type":43},"2025-07-17",{"date":620,"type":43},"2025-06-10",{"date":622,"type":22},"2025-10-10",{"name":49,"class":50},{"id":625,"slug":626,"hasResults":12,"nctId":627,"briefTitle":628,"officialTitle":629,"acronym":4,"eligibilityCriteria":630,"healthyVolunteers":245,"sex":136,"minAge":18,"maxAge":4,"enrollmentInfo":631,"targetDuration":4,"studyType":23,"phases":632,"briefSummary":633,"conditions":634,"keywords":637,"overallStatus":69,"whyStopped":4,"lastUpdateSubmitDate":553,"lastUpdatePostDateStruct":640,"startDateStruct":642,"completionDateStruct":644,"leadSponsor":646,"locationsCount":51},"100585022","effects-of-virtual-reality-application-and-progressive-relaxation-exercise-100585022","NCT06896955","Effects of Virtual Reality Application and Progressive Relaxation Exercise","Effects of Virtual Reality Application and Progressive Relaxation Exercise Training on Pregnant Women's Stress, Birth Affect and Birth Self-Efficacy","Inclusion Criteria:\n\n* Voluntary participation\n* No communication difficulties (no mental retardation, no visual\u002Fhearing impairment)\n* Knowing Turkish and being literate\n* No fetal anomalies\n* Being in the 32nd week of pregnancy\n* Not being diagnosed with a risky pregnancy (multiple pregnancy, premature rupture of membranes, preeclampsia, gestational diabetes, placenta previa, etc., pregnancies may end with a cesarean section)\n\nExclusion Criteria:\n\n* Having a psychiatric disease diagnosis",{"count":224,"type":22},[25],"In the study, random assignment and randomization concealment will be applied to control selection bias. Pregnant women were assigned to groups by an independent statistician using the block randomization method. For this purpose, 6-digit combinations consisting of the letters \"A\", \"B\" and \"C\" were first created in the randomization of 78 women.",[635,636,422],"Pregnancy","Exercise",[635,636,638,639],"progressive exercise","virtual reality",{"date":641,"type":43},"2025-03-26",{"date":643,"type":22},"2025-03-25",{"date":645,"type":22},"2026-03-25",{"name":49,"class":50},""]