[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Dalarna County Council, Sweden\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":270},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,10,0,[8,45,71,93,111,140,168,191,211,242],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":4,"briefSummary":22,"conditions":23,"keywords":27,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":33,"lastUpdatePostDateStruct":34,"startDateStruct":37,"completionDateStruct":39,"leadSponsor":41,"locationsCount":44},"100636830","stability-of-hand-grip-strength-across-a-competitive-season-in-elite-male-and-female-ice-hockey-players-100636830",false,"NCT07570784","Stability of Hand Grip Strength Across a Competitive Season in Elite Male and Female Ice Hockey Players","Stability of Hand Grip Strength Across a Competitive Season in Elite Male and Female Ice Hockey Players: A Prospective Longitudinal Observational Cohort Study","Inclusion Criteria:\n\n* Contracted elite ice hockey players in participating Swedish teams (SHL, HockeyAllsvenskan, SDHL or equivalent top division)\n* Male or female players competing at elite level\n* Available for testing at all predefined measurement timepoints across the season\n* Able to perform maximal hand grip strength testing\n* Provides informed consent\n\nExclusion Criteria:\n\n* Acute hand or wrist injury at baseline preventing maximal grip strength testing\n* Any condition during the study period preventing completion of repeated grip strength assessments\n* Inability to participate in all scheduled measurement sessions\n* Refusal to participate","ALL","18 Years",{"count":19,"type":20},150,"ESTIMATED","OBSERVATIONAL","This study examines how hand grip strength changes over the course of a competitive ice hockey season in elite male and female players.\n\nHand grip strength is a simple and widely used measure of upper-body strength and functional capacity. It is often used in sports science and clinical settings, but it is unclear whether grip strength remains stable throughout a season or changes depending on training load, match exposure, and fatigue.\n\nIn this study, elite ice hockey players from Swedish teams will have their grip strength measured at four timepoints during one season: pre-season, early season, mid-season, and late season. Both dominant and non-dominant hand strength will be assessed using a standardized dynamometer and protocol.\n\nThe main purpose is to determine how much grip strength varies within individual players over time and whether a single measurement can be considered representative of a player's true strength level across a season. The study will also evaluate the reliability of grip strength measurements and whether observed changes are large enough to be meaningful in a clinical or performance context.\n\nNo intervention is performed, and all measurements are non-invasive and conducted as part of routine testing environments within participating teams.",[24,25,26],"Ice Hockey","Grip Strength","Within-season Variability",[28,29,30,31],"ice hockey","hand grip strength","within-season variability","test-retest reliability","NOT_YET_RECRUITING","2026-06-04",{"date":35,"type":36},"2026-06-05","ACTUAL",{"date":38,"type":20},"2026-09",{"date":40,"type":20},"2027-12-31",{"name":42,"class":43},"Dalarna County Council, Sweden","OTHER",1,{"id":46,"slug":47,"hasResults":11,"nctId":48,"briefTitle":49,"officialTitle":50,"acronym":4,"eligibilityCriteria":51,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":52,"targetDuration":4,"studyType":21,"phases":4,"briefSummary":54,"conditions":55,"keywords":60,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":33,"lastUpdatePostDateStruct":65,"startDateStruct":66,"completionDateStruct":68,"leadSponsor":70,"locationsCount":44},"100640382","medical-team-perspectives-on-hand-and-wrist-injuries-in-elite-male-and-female-ice-hockey-players-100640382","NCT07586085","Medical Team Perspectives on Hand and Wrist Injuries in Elite Male and Female Ice Hockey Players","Medical Team Perspectives on Hand and Wrist Injuries in Elite Ice Hockey: A Cross-Sectional Survey Study in Male and Female Players","Inclusion Criteria:\n\n* Physiotherapists working with elite ice hockey teams in Sweden (SHL, HockeyAllsvenskan, SDHL)\n* Team physicians working with elite ice hockey teams in Sweden (SHL, HockeyAllsvenskan, SDHL)\n* Massage therapists and sports massage practitioners working with elite ice hockey teams in Sweden\n* Athletic trainers and performance staff involved in player health and injury management in elite ice hockey teams in Sweden\n* Currently active in a medical or performance support role within a participating elite ice hockey team during the study period\n* Able to understand and complete the questionnaire in Swedish or English Provides informed consent\n\nExclusion Criteria:\n\n* Refusal to participate\n* Not currently active in a medical, therapeutic, or performance support role within elite ice hockey during the study period",{"count":53,"type":20},50,"This is a cross-sectional survey study investigating how medical team staff in elite Swedish ice hockey perceive hand and wrist injuries in male and female players.\n\nHand and wrist injuries are common in ice hockey and can affect both performance and participation. While injury registries describe how often these injuries occur, less is known about how they are managed and prioritised in daily clinical practice, or whether there are differences in perception between medical teams working in male and female elite leagues.\n\nIn this study, physiotherapists and team physicians working in Swedish elite ice hockey (including SHL, HockeyAllsvenskan, and SDHL) will complete a structured questionnaire. The survey examines perceptions of injury frequency, underreporting, functional impact, clinical management strategies, and return-to-play decision-making related to hand and wrist injuries.\n\nThe aim is to better understand how medical teams experience and manage these injuries in real-world elite sport settings, and to identify potential gaps between epidemiological data and clinical practice. The study may help inform future injury prevention strategies, improve clinical decision-making, and support the development of more standardized management approaches in elite ice hockey.\n\nNo interventions or treatments are performed in this study.",[24,56,57,58,59],"Hand","Wrist","Injuries","Medical Staff Perception",[28,61,62,63,64],"hand","wrist","medical staff perception","cross-sectional survey",{"date":35,"type":36},{"date":67,"type":20},"2026-09-01",{"date":69,"type":20},"2026-12-31",{"name":42,"class":43},{"id":72,"slug":73,"hasResults":11,"nctId":74,"briefTitle":75,"officialTitle":76,"acronym":4,"eligibilityCriteria":77,"healthyVolunteers":11,"sex":16,"minAge":78,"maxAge":4,"enrollmentInfo":79,"targetDuration":4,"studyType":21,"phases":4,"briefSummary":81,"conditions":82,"keywords":85,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":87,"lastUpdatePostDateStruct":88,"startDateStruct":90,"completionDateStruct":91,"leadSponsor":92,"locationsCount":4},"100638381","prevalence-and-functional-impact-of-hand-and-wrist-symptoms-in-ice-hockey-players-100638381","NCT07586033","Prevalence and Functional Impact of Hand and Wrist Symptoms in Ice Hockey Players","Prevalence and Functional Impact of Hand and Wrist Symptoms in Ice Hockey Players: A Cross-Sectional Survey Study","Inclusion Criteria:\n\n* Active ice hockey players currently registered on a participating team roster in Sweden.\n* Male or female players competing at elite, junior elite, or amateur level.\n* Participation in one of the included competition levels during the current season.\n* Able to understand and complete the questionnaire.\n* Provides written informed consent.\n\nExclusion Criteria:\n\n* Declines participation.\n* Inability to complete the survey due to language barriers or cognitive limitations.\n* Acute severe upper-limb injury at time of data collection preventing meaningful survey completion, if deemed necessary for context-specific exclusion.","15 Years",{"count":80,"type":20},800,"Ice hockey places high physical demands on the hands and wrists due to frequent shooting, passing, and physical contact. This study aims to understand how common hand and wrist pain or symptoms are among ice hockey players in Sweden, and how these symptoms affect training, participation, and performance.\n\nPlayers from different competitive levels (elite, junior, and amateur) and both sexes will complete a structured questionnaire based on the validated Oslo Sports Trauma Research Centre (OSTRC) tool, along with questions about pain intensity, symptom characteristics, and functional impact.\n\nThe goal is to describe the prevalence and severity of hand and wrist symptoms across different groups of players and to identify potential differences between sex, playing level, and position. No treatment or intervention is involved.",[56,57,83,84],"Overuse Injury","Ice Hockey Players",[86],"ice hockey, hand and wrist symptoms, OSTRC questionnaire, sports injuries, cross-sectional survey","2026-05-22",{"date":89,"type":36},"2026-05-27",{"date":67,"type":20},{"date":69,"type":20},{"name":42,"class":43},{"id":94,"slug":95,"hasResults":11,"nctId":96,"briefTitle":97,"officialTitle":97,"acronym":4,"eligibilityCriteria":98,"healthyVolunteers":11,"sex":16,"minAge":78,"maxAge":4,"enrollmentInfo":99,"targetDuration":4,"studyType":21,"phases":4,"briefSummary":100,"conditions":101,"keywords":103,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":87,"lastUpdatePostDateStruct":107,"startDateStruct":108,"completionDateStruct":109,"leadSponsor":110,"locationsCount":4},"100636581","normative-hand-grip-strength-values-in-swedish-male-and-female-ice-hockey-players-across-competitive-levels-100636581","NCT07567547","Normative Hand Grip Strength Values in Swedish Male and Female Ice Hockey Players Across Competitive Levels","Inclusion Criteria:\n\n* Adult male or female ice hockey players.\n* Registered and actively participating in a Swedish ice hockey club during the current season.\n* Participation in one of the included competitive levels: professional, semi-professional, junior elite, or recreational leagues in Sweden.\n* Able to perform maximal hand grip strength testing. Provides written informed consent.\n\nExclusion Criteria:\n\n* Current acute injury of the upper extremity (hand, wrist, forearm, or elbow) that prevents safe or valid grip strength testing.\n* Any medical condition that contraindicates maximal effort testing, as determined by team medical staff or study personnel.\n* Refusal or inability to provide informed consent.",{"count":80,"type":20},"This study measures hand grip strength in male and female ice hockey players across different Swedish leagues to create reference (normative) values for adult players.\n\nHand grip strength is a simple test of how strongly a person can squeeze with their hand. Although it seems basic, it reflects overall upper-body strength and is widely used in both sports science and healthcare.\n\nIn this project, players from different levels of ice hockey (including professional men's and women's leagues, junior players, and recreational players if available) will have their grip strength measured using a standardized hand dynamometer. Measurements will be taken in a consistent way across all participating clubs.\n\nThe main goal is to build a reference database showing what \"normal\" grip strength looks like in ice hockey players depending on sex, league level, and playing position. This can help coaches, medical staff, and researchers better understand strength profiles in hockey athletes, support training and rehabilitation decisions, and provide benchmarks for future studies.\n\nNo treatment or intervention is given as part of the study.",[25,102,84],"Normative Values",[28,104,105,106],"athletes","grip strength","normative data",{"date":89,"type":36},{"date":67,"type":20},{"date":69,"type":20},{"name":42,"class":43},{"id":112,"slug":113,"hasResults":11,"nctId":114,"briefTitle":115,"officialTitle":116,"acronym":117,"eligibilityCriteria":118,"healthyVolunteers":11,"sex":119,"minAge":17,"maxAge":4,"enrollmentInfo":120,"targetDuration":4,"studyType":122,"phases":123,"briefSummary":125,"conditions":126,"keywords":128,"overallStatus":131,"whyStopped":4,"lastUpdateSubmitDate":132,"lastUpdatePostDateStruct":133,"startDateStruct":135,"completionDateStruct":137,"leadSponsor":139,"locationsCount":44},"100639682","effects-of-negative-pressure-wound-bandaging-after-mastectomy-100639682","NCT07607366","Effects of Negative Pressure Wound Bandaging After Mastectomy","Is Negative Pressure Wound Therapy Associated With a Decreased Risk of Postoperative Seroma in Breast Cancer Patients Who Have Undergone Mastectomy?","NEPTAM","Inclusion Criteria:\n\n* Breast cancer patients undergoing mastectomy\n* Female\n* Age \\>= 18 years\n\nExclusion Criteria:\n\n* Direct reconstruction with implants\n* The use of Harmonic Johnson and Johnson instrument during surgery","FEMALE",{"count":121,"type":20},76,"INTERVENTIONAL",[124],"NA","Participant information sheet Mastectomy is a surgical method used to treat breast cancer. A mastectomy involves the removal of the entire breast. A common postoperative complication after a mastectomy is seroma, i.e. an abnormal accumulation of serous fluid in the wound cavity. At present, at Falu Lasarett, we use conventional dressings on the wound after the operation as well as an active drainage that is left in place for a couple of days. There is research that suggests that negative pressure dressings can promote wound healing and reduce the formation of seroma. The purpose of this study is to investigate whether negative pressure dressings reduce the risk of postoperative seroma compared to regular dressings. We will also look at whether it reduces the risk of other postoperative complications such as infection, bleeding and wound healing problems. We are asking all patients who will undergo a mastectomy in 2025 if they want to participate in our study. The Director of Research, Education and Innovation is the authorized representative of the research principal (which is the legal entity Region Dalarna). Research principal means the organization responsible for the project. The research is approved by the Ethics Review Authority, the registry number for the trial at the Ethics Review Authority is 2025-00006-01. How does the project work? Participating in our study means that on the day of surgery you will be randomized between two groups. One group will receive conventional wound dressings, and the other group will receive PICO negative pressure dressings. The negative pressure dressing is connected to a small canister that is worn for 7 days. Just like today, there will be a return visit to the nurse in the surgery ward after a day to check and possibly remove the active drain. There will also be a return visit to the doctor after 2-3 weeks for results of the tissue analysis and information about further treatment. The additional visit if you participate in our study is a return visit to the nurse after 7 days to remove the PICO negative pressure dressing (if you belong to that group). A return visit to the nurse is also planned after 6 months as a follow-up. If you have any questions or problems, you can contact your contact nurse. Possible consequences and risks of participating in the project The PICO negative pressure dressing is connected to a cord with a small canister that must be carried with you. The canister fits in a pocket. The canister is on 24 hours a day and emits a light vibration sound. What happens to your data? The project will collect and register information about you. Information about your medical history, measurements, medications, type of surgical procedure, number of return visits after surgery and postoperative complications will be collected from your medical record to analyze our results. The data will be pseudonymized and entered into a password-protected Excel document for analysis. The code key is stored in a lock-protected Excel file. The code key is processed so that unauthorized persons cannot access it. Your answers and your results will be processed so that unauthorized persons cannot access them. The code key and research data are stored for 10 years in accordance with research ethics because it should be possible to go back to the research data and re-analyze if question marks arise about our analysis methods. The data protection officer of Region Dalarna is responsible for your personal data. According to the EU Data Protection Regulation, you have the right to access the data about you that is handled in the project free of charge, and to have any errors corrected if necessary. You can also request that data about you be deleted and that the processing of your personal data be restricted. However, the right to deletion and restriction of processing of personal data does not apply when the data is necessary for the current research. If you would like to access the data, please contact the principal investigator (Rebecca Paul, rebecca.paul@regiondalarna.se, 023 490760). The data protection officer can be reached at dataskyddsombud@regiondalarna.se, Tel: 023-490000. If you are dissatisfied with how your personal data is processed, you have the right to file a complaint with the Swedish Data Protection Authority, which is the supervisory authority. How do you get information about the results of the project? You can access your individual data in your medical record. The results of the entire study will be reported internally at Kirurgkliniken Falu Lasarett and are intended to be published in a scientific journal. Unforeseen findings will be handled through follow-up and, if necessary, treatment. Insurance and compensation Patient insurance valid through the research principal. You will not receive compensation as the study is part of a planned procedure. Participation is voluntary.",[127],"Breast Cancer - Female",[129,130],"Breast cancer. Mastectomy. Negative pressure wound therapy. Seroma.","Surgical site complications.","RECRUITING","2026-05-19",{"date":134,"type":36},"2026-05-26",{"date":136,"type":36},"2025-03-01",{"date":138,"type":20},"2027-09-01",{"name":42,"class":43},{"id":141,"slug":142,"hasResults":11,"nctId":143,"briefTitle":144,"officialTitle":145,"acronym":4,"eligibilityCriteria":146,"healthyVolunteers":147,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":148,"targetDuration":4,"studyType":21,"phases":4,"briefSummary":150,"conditions":151,"keywords":156,"overallStatus":131,"whyStopped":4,"lastUpdateSubmitDate":160,"lastUpdatePostDateStruct":161,"startDateStruct":163,"completionDateStruct":165,"leadSponsor":167,"locationsCount":44},"100469356","cardiac-function-in-swimming-induced-pulmonary-edema-sipe-100469356","NCT05391737","Cardiac Function in Swimming-Induced Pulmonary Edema (SIPE)","Cardiac Function in Swimming-Induced Pulmonary Edema (SIPE) - a Case Control Study","Inclusion Criteria:\n\nfor patients:\n\n* respiratory symptoms during or after swimming at the Vansbrosimningen open water swimming event\n* diagnosis SIPE by signs of pulmonary edema on lung ultrasound\n* peripheral oxygen saturation ≤95%\n\nfor controls:\n\n* completion of a swimming race of the Vansbrosimningen open water swimming event.\n* no respiratory symptoms during or after swimming\n* no signs of pulmonary edema on lung ultrasound\n* matched to patients with SIPE regarding sex and age\n\nExclusion criteria:\n\n* declined consent\n* hemodynamic instability or decreased consciousness",true,{"count":149,"type":20},120,"Acute or chronic cardiac dysfunction could be a contributing factor to swimming-induced pulmonary edema (SIPE). Knowledge on cardiac function in SIPE is limited and recommendations for cardiac evaluation of patients with SIPE are lacking. The present study was designed to assess cardiac function in patients with SIPE and in asymptomatic swimmers.",[152,153,154,155],"Swimming Induced Pulmonary Edema (SIPE)","Pulmonary Edema","Lung Diseases","Heart Function Tests",[157,158,159],"Echocardiography","Electrocardiography","Troponin","2025-02-25",{"date":162,"type":36},"2025-02-27",{"date":164,"type":36},"2022-07-06",{"date":166,"type":20},"2026-12",{"name":42,"class":43},{"id":169,"slug":170,"hasResults":11,"nctId":171,"briefTitle":172,"officialTitle":173,"acronym":4,"eligibilityCriteria":174,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":175,"targetDuration":4,"studyType":122,"phases":177,"briefSummary":178,"conditions":179,"keywords":180,"overallStatus":131,"whyStopped":4,"lastUpdateSubmitDate":160,"lastUpdatePostDateStruct":185,"startDateStruct":186,"completionDateStruct":188,"leadSponsor":190,"locationsCount":44},"100456717","pep-device-for-treatment-of-swimming-induced-pulmonary-edema-sipe-100456717","NCT05227222","PEP-device for Treatment of Swimming-induced Pulmonary Edema (SIPE)","Evaluation of Positive Expiratory Pressure Device (PEP-device) for Treatment of Swimming Induced Pulmonary Edema (SIPE) - a Randomized Single-blinded Controlled Study","Inclusion Criteria:\n\n* clinical diagnosis of swimming induced pulmonary edema (SIPE) with need of acute treatment\n* peripheral oxygen saturation ≥92%\n* 18 years or older\n* informed consent\n\nExclusion Criteria:\n\n* declined consent\n* suspected acute coronary syndrome\n* severe asthma diagnosed together with pulmonary edema with requirement of beta-agonist-inhalation prior to treatment of pulmonary edema\n* hemodynamic instability or decreased consciousness",{"count":176,"type":20},40,[124],"In swimming induced pulmonary edema (SIPE), there is a lack of knowledge regarding optimal treatment. The present study was designed to assess the benefit of treatment with positive expiratory pressure device (PEP-device) compared to spontaneous recovery in patients with SIPE without hypoxia in the out-of-hospital environment.",[152,153,154],[181,182,183,184],"positive expiratory pressure","therapeutics","ultrasonography","oximetry",{"date":162,"type":36},{"date":187,"type":36},"2022-07-02",{"date":189,"type":20},"2027-07-15",{"name":42,"class":43},{"id":192,"slug":193,"hasResults":11,"nctId":194,"briefTitle":195,"officialTitle":196,"acronym":197,"eligibilityCriteria":198,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":199,"targetDuration":4,"studyType":122,"phases":201,"briefSummary":202,"conditions":203,"keywords":204,"overallStatus":131,"whyStopped":4,"lastUpdateSubmitDate":160,"lastUpdatePostDateStruct":207,"startDateStruct":208,"completionDateStruct":209,"leadSponsor":210,"locationsCount":44},"100386122","o2-versus-cpap-treatment-of-patients-undergoing-sipe-therapy-octopus-100386122","NCT04307615","O2 Versus CPAP Treatment of Patients Undergoing SIPE Therapy (OCTOPUS)","Evaluation of Continous Positive Airway Pressure (CPAP) in Swimming Induced Pulmonary Edema (SIPE) -a Randomized Single-blinded Controlled Study","OCTOPUS","Inclusion Criteria:\n\n* clinical diagnosis of swimming induced pulmonary edema (SIPE) with need of acute treatment (oxygen saturation ≤91%)\n* 18 years and older\n* informed consent\n\nExclusion Criteria:\n\n* declined consent\n* suspected acute coronary syndrome\n* severe asthma diagnosed together with pulmonary edema where beta-agonist-inhalation is needed prior to treatment of pulmonary edema\n* hemodynamic instability or decreased consciousness",{"count":200,"type":20},90,[124],"In swimming induced pulmonary edema (SIPE), there is a lack of knowledge regarding optimal treatment. The present study was designed to assess the benefit of continuous positive airway pressure (CPAP) compared to oxygen as a first line treatment of SIPE in the out-of-hospital environment.",[152,153,154],[205,206,182,183,184],"continuous positive airway pressure (CPAP)","oxygen",{"date":162,"type":36},{"date":187,"type":36},{"date":189,"type":20},{"name":42,"class":43},{"id":212,"slug":213,"hasResults":11,"nctId":214,"briefTitle":215,"officialTitle":216,"acronym":217,"eligibilityCriteria":218,"healthyVolunteers":11,"sex":16,"minAge":219,"maxAge":220,"enrollmentInfo":221,"targetDuration":4,"studyType":122,"phases":223,"briefSummary":225,"conditions":226,"keywords":231,"overallStatus":131,"whyStopped":4,"lastUpdateSubmitDate":234,"lastUpdatePostDateStruct":235,"startDateStruct":237,"completionDateStruct":239,"leadSponsor":240,"locationsCount":241},"100345745","phase-4-evaluation-of-cortisone-treatment-in-children-with-acute-facial-nerve-palsy-100345745","NCT03781700","Evaluation of Cortisone Treatment in Children With Acute Facial Nerve Palsy","The Facial Nerve Palsy And Cortisone Evaluation (FACE) Study in Children: A Randomized Double-blind, Placebo-controlled, Multicenter Trial","FACE","Inclusion Criteria:\n\n1. 1-17 years of age\n2. Acute peripheral unilateral facial nerve palsy\n3. Less than 72 hours since debut of symptoms\n4. Signed informed consent\n\nExclusion Criteria:\n\n1. Head trauma \\\u003C1 month\n2. Central or bilateral facial nerve palsy\n3. Malformations in head and neck\n4. Conditions not compatible with cortisone treatment (arterial hypertension, diabetes mellitus, psychiatric disorder, active or latent tuberculosis, intolerance of lactose)\n5. Current or past oncological diagnosis\n6. Other serious medical conditions (meningitis, encephalitis, stroke)\n7. Acute otitis media\n8. Signs of herpes simplex or varicella zoster infection (vesicles in the ear region)\n9. Pregnancy or breastfeeding\n10. Use of any systemic or inhaled steroids within 2 weeks prior onset of symptoms\n11. Immunization with live vaccine 1 month prior onset of symptoms\n12. Requirement of live vaccine within 2 months from start of experimental treatment (prednisolone or placebo)\n13. Evaluation of primary endpoint at 12 months not feasible for any reason\n14. Previously included into the FACE study","1 Year","17 Years",{"count":222,"type":20},500,[224],"PHASE4","Acute facial nerve palsy occur in 10-20\u002F100 000 children\u002Fyear in Sweden. About 20 % of these children will have persistent symptoms with excessive tear secretion, drooling and social problems due to asymmetry in the face. Studies on cortisone treatment to adult patients with acute facial nerve palsy have shown beneficial effects, but no studies with strong quality have been performed in children.\n\nInvestigators will perform a double-blind randomized placebo-controlled multicenter trial on children with acute facial nerve palsy. Participants will be recruited consecutively at 9-12 study centers in Sweden during 2019-2020. Oral cortisone (prednisolone) 1 mg\u002Fkg x 1 in 10 days (or placebo) will be started on admission. Clinical data, including recovery will be followed-up until 12 months.\n\nThe primary outcome is defined as total recovery of the facial nerve palsy, measured with the House-Brackmann scale (grade 1) at 12-months follow-up.\n\nThe overall purpose is to assess the utility of cortisone treatment given to children with acute facial nerve palsy in this study. If the total recovery rate is significantly improved in the prednisolone group as compared to the placebo group, prednisolone treatment will be introduced in clinical practice for children with acute facial nerve palsy in order to reduce the risk of persistent symptoms.",[227,228,229,230],"Facial Palsy","Facial Nerve Diseases","Borrelia Infection of Central Nervous System","Bell Palsy",[232,233],"Children","Paediatric","2025-02-20",{"date":236,"type":36},"2025-02-21",{"date":238,"type":36},"2019-05-03",{"date":69,"type":20},{"name":42,"class":43},15,{"id":243,"slug":244,"hasResults":11,"nctId":245,"briefTitle":246,"officialTitle":247,"acronym":248,"eligibilityCriteria":249,"healthyVolunteers":147,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":250,"targetDuration":4,"studyType":122,"phases":252,"briefSummary":253,"conditions":254,"keywords":256,"overallStatus":131,"whyStopped":4,"lastUpdateSubmitDate":262,"lastUpdatePostDateStruct":263,"startDateStruct":265,"completionDateStruct":267,"leadSponsor":269,"locationsCount":44},"100462075","oral-cancer-screening-for-early-detection-of-premalignant-disorders-pmod-100462075","NCT05296941","Oral Cancer Screening for Early Detection of Premalignant Disorders (PMOD)","Screening for Oral Cancer for Early Detection of Premalignant Disorders","PMOD","Inclusion Criteria:\n\n• Persons 18 years of age or older who have the clinical diagnosis of leukoplakia, erythroplakia or proliferative verrukös leukoplakia\n\nExclusion Criteria:\n\n* People who cannot read and understand information in Swedish.\n* Ongoing chemotherapy and\u002For radiotherapy.",{"count":251,"type":20},200,[124],"Cancer is a complex disease; its different causes and types have a strong impact on patient treatment and prognosis. To improve understanding of the disease, its causes and progression, the investigators will develop a simple, cost-effective system for continuous control of mucosal lesions with non-invasive brush biopsy that can be managed in primary dental care, as an alternative to tissue biopsy in order to reduce the number of oral cavity cancers.",[255],"Mouth Neoplasms",[257,258,259,260,261],"oral cancer","potentially malignant disorders","leukoplakia","erythroplakia","oral lichen planus","2023-09-06",{"date":264,"type":36},"2023-09-08",{"date":266,"type":36},"2023-08-01",{"date":268,"type":20},"2029-12-31",{"name":42,"class":43},""]