[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Damian Ratano\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":46},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":26,"conditions":27,"keywords":29,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":35,"lastUpdatePostDateStruct":36,"startDateStruct":39,"completionDateStruct":41,"leadSponsor":43,"locationsCount":5},"100383511","phase-2-anticoagulation-free-vv-ecmo-for-acute-respiratory-failure-100383511",false,"NCT04273607","Anticoagulation-free VV ECMO for Acute Respiratory Failure","Anticoagulation-free VV ECMO for Acute Respiratory Failure: A Pilot Safety and Feasibility Randomized Clinical Trial","A-FREE ECMO","Inclusion Criteria:\n\n* Adult patient with ARDS on VV-ECMO\n\nExclusion Criteria:\n\n* Contraindication to anticoagulation with UFH (known heparin-induced thrombocytopenia, active hemorrhage, any surgery precluding the use of anticoagulation),\n* Indication for therapeutic anticoagulation (pulmonary embolism or deep vein thrombosis, chronic anticoagulation therapy before ECMO insertion)\n* Low-flow (\\\u003C2 liters\u002Fmin) VV-ECMO (ECCO2R)","ALL","18 Years",{"count":20,"type":21},40,"ESTIMATED","INTERVENTIONAL",[24,25],"PHASE2","PHASE3","Currently international experts recommend therapeutic anticoagulation for veno-venous extracorporeal membrane oxygenation (VV-ECMO). Reports and case series suggest that the absence of therapeutic anticoagulation is safe for VV-ECMO. No randomized control trials have assessed this. The aim of this pilot study is to assess safety and feasibility of an \"anticoagulation-free strategy\" for veno-venous ECMO (VV-ECMO) in Acute respiratory distress syndrome (ARDS).",[28],"Extracorporeal Membrane Oxygenation Complication",[30,31,32,33],"Extracorporeal membrane oxygenation","Anticoagulation","Thrombosis","Hemorrhage","RECRUITING","2026-01-14",{"date":37,"type":38},"2026-01-16","ACTUAL",{"date":40,"type":38},"2022-09-01",{"date":42,"type":21},"2027-01-30",{"name":44,"class":45},"Damian Ratano","OTHER",""]