[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Dar Al Uloom University\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":121},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,4,0,[8,42,72,96],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":11,"sex":15,"minAge":16,"maxAge":17,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":25,"conditions":26,"keywords":4,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":30,"lastUpdatePostDateStruct":31,"startDateStruct":34,"completionDateStruct":36,"leadSponsor":38,"locationsCount":41},"100592061","phase-2-treatment-outcomes-and-patient-satisfaction-of-oral-lichen-planus-treatment-100592061",false,"NCT06988527","Treatment Outcomes and Patient Satisfaction of Oral Lichen Planus Treatment","Inclusion Criteria:\n\n* Patients with a clinical diagnosis of oral lichen planus\n* Symptomatic OLP lesions (erosive\u002Fatrophic)\n* Participants are between 35 and 60 years old, who are able to adhere to the study protocol, and sign informed consent.\n\nExclusion Criteria:\n\n* Patients with other oral mucosal disorders, or systemic conditions influencing OLP or wound healing, allergies or hypersensitivity to honey or triamcinolone\n* Patients who administer systemic corticosteroids or immunosuppressive agents.\n* Pregnancy or lactation\n* Inability to comprehend or adhere to study directives\n* Patients who are not able to sign an informed written consent","ALL","35 Years","60 Years",{"count":19,"type":20},56,"ESTIMATED","INTERVENTIONAL",[23,24],"PHASE2","PHASE3","The goal of this clinical trial is to assess Honey in orabase (1:1) for treating patients with OLP and improving their quality of life:\n\nThe research question aims to answer:\n\nDoes honey in orabase (1:1) improve or reduce OLP symptoms compared to the standardized treatment by triamcinolone acetonide 0.1% drug and improve the patient's quality of life?\n\nParticipants will:\n\nTake drug ABC or a placebo every day for 4 months Visit the clinic once every 2 weeks for checkups and tests Keep a diary of their symptoms and the number of times they use a rescue inhaler",[27,28],"Erosive Oral Lichen Planus","Atrophic Lichen Planus","RECRUITING","2026-02-12",{"date":32,"type":33},"2026-02-17","ACTUAL",{"date":35,"type":33},"2025-05-20",{"date":37,"type":20},"2026-06-30",{"name":39,"class":40},"Dar Al Uloom University","OTHER",1,{"id":43,"slug":44,"hasResults":11,"nctId":45,"briefTitle":46,"officialTitle":47,"acronym":4,"eligibilityCriteria":48,"healthyVolunteers":11,"sex":15,"minAge":49,"maxAge":50,"enrollmentInfo":51,"targetDuration":4,"studyType":21,"phases":53,"briefSummary":55,"conditions":56,"keywords":60,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":64,"lastUpdatePostDateStruct":65,"startDateStruct":67,"completionDateStruct":69,"leadSponsor":71,"locationsCount":41},"100595256","evaluation-of-a-novel-dual-headed-toothbrush-design-for-periodontal-health-split-mouth-randomized-blind-clinical-trial-100595256","NCT07030088","Evaluation of a Novel Dual-Headed Toothbrush Design for Periodontal Health: Split-Mouth Randomized Blind Clinical Trial","Clinical and Patient-Based Evaluation of a Novel Dual-Headed Toothbrush Design: Split-Mouth Clinical Trial","Inclusion Criteria:\n\n* • Dentists with a minimum of 26 natural teeth, good general health, and the ability to perform routine oral hygiene independently.\n\n  * No systemic diseases affecting oral hygiene.\n  * Record of mild-to-moderate plaque accumulation; PI score ≥ 1\n  * Rt handed dentists\n\nExclusion Criteria:\n\n* • Participants with active periodontal disease, orthodontic appliances, or having recent oral surgery\n\n  * Those currently enrolled in any other dental trial\n  * Smokers.","25 Years","40 Years",{"count":52,"type":20},40,[54],"NA","The goal of this clinical trial is to evaluate the effectiveness and patient satisfaction of a novel dual-headed toothbrush design compared to a conventional single-headed toothbrush in adult dental professionals aged 22-45 years with healthy gingival conditions. The main questions it aims to answer are:\n\nDoes the dual-headed toothbrush improve plaque removal efficiency compared to a single-headed toothbrush? Does the dual-headed toothbrush enhance brushing comfort, reduce brushing time, and improve user satisfaction? Researchers will compare the side of the mouth (cleaned with a dual-headed toothbrush) with the other side (cleaned with a single-headed toothbrush) in a randomized split-mouth design to see if the novel design leads to superior plaque control and better user experience.\n\nParticipants will:\n\nReceive both toothbrush types (medium bristle) and identical toothpaste Be trained in the Bass brushing technique Use each toothbrush, twice daily, with the assigned toothbrush applied to its designated side of the mouth\n\nComplete post-trial questionnaires on comfort, ease of use, and brushing time",[57,58,59],"Dental Plaque Accumulation","Oral Hygiene Education Methods","Toothbrushing",[61,62,63],"Dual-headed toothbrush","Single-headed toothbrush","Toothbrushing technique","2025-09-05",{"date":66,"type":33},"2025-09-11",{"date":68,"type":20},"2025-09",{"date":70,"type":20},"2025-12",{"name":39,"class":40},{"id":73,"slug":74,"hasResults":11,"nctId":75,"briefTitle":76,"officialTitle":76,"acronym":4,"eligibilityCriteria":77,"healthyVolunteers":78,"sex":15,"minAge":79,"maxAge":50,"enrollmentInfo":80,"targetDuration":4,"studyType":21,"phases":82,"briefSummary":84,"conditions":85,"keywords":4,"overallStatus":87,"whyStopped":4,"lastUpdateSubmitDate":88,"lastUpdatePostDateStruct":89,"startDateStruct":91,"completionDateStruct":93,"leadSponsor":95,"locationsCount":41},"100593906","phase-1-clinical-evaluation-of-photobiomodulated-hyaluronic-acid-therapy-for-interdental-papillary-loss-minimal-invasive-blind-split-mouth-technique-100593906","NCT07012525","Clinical Evaluation of Photobiomodulated Hyaluronic Acid Therapy for Interdental Papillary Loss: Minimal Invasive Blind Split Mouth Technique","Inclusion Criteria:\n\n* Adults aged 20 to 40 years\n* Presence of at least two non-adjacent interdental papilla defects (Class I, Norland \\& Tarnow classification) in the maxillary anterior region\n* Healthy periodontal status, with:\n* Probing depth ≤ 3 mm\n* No gingival recession\n* No tooth mobility (Score 0)\n* No interdental bone loss on radiographs\n* Non-smokers\n* No previous orthodontic treatment\n* Free from gingival or dental surface alterations (e.g., abfraction, irregularities, or overcontouring)\n* Systemically healthy (no systemic diseases or conditions affecting healing or immune function)\n* Willing and able to comply with study procedures and follow-up visits\n* Provided written informed consent after explanation of study procedures\n\nExclusion Criteria:\n\n* Candidates will be excluded if they meet any of the following:\n* Systemic diseases or medications known to affect soft tissue healing (e.g., diabetes, immunosuppressants)\n* Pregnancy or lactation\n* History of periodontal surgery in the study area\n* Known allergy or hypersensitivity to hyaluronic acid or local anesthetics\n* Current use of anti-inflammatory drugs, anticoagulants, or antibiotics that could affect healing\n* Poor oral hygiene or non-compliance during pre-treatment phase\n* Participation in another clinical trial within the last 3 months",true,"20 Years",{"count":81,"type":20},14,[83,23],"PHASE1","The goal of this clinical trial is to evaluate the effectiveness of a minimally invasive therapy combining photobiomodulation (PBMT) with injectable dermal filler (hyaluronic acid) in adult patients (ages 20-40) with interdental papillary loss (Norland \\& Tarnow Class I) in the maxillary anterior region.\n\nThe main questions it aims to answer are:\n\nDoes PBMT enhance the regenerative effect of hyaluronic acid filler in restoring the interdental papilla? Is the combined therapy superior to dermal filler alone in achieving long-term aesthetic and clinical stability?\n\nResearchers will compare:\n\nGroup I (control) - hyaluronic acid filler alone vs. Group II (experimental) - PBMT applied before and after hyaluronic acid filler to see if PBMT contributes to better papilla height, width, and volume restoration over 12 months.\n\nParticipants will:\n\nUndergo standard periodontal cleaning and education 4 weeks before treatment Receive local anesthesia and dermal filler injections in both quadrants (split-mouth design)\n\nHave PBMT applied in one quadrant only (Group II) Be followed up at regular intervals (1 week to 12 months) for clinical measurements and digital image analysis of papilla dimensions This study introduces a non-surgical, patient-friendly technique that may enhance soft tissue regeneration in esthetic areas, offering a potential breakthrough in managing interdental papillary loss.",[86],"Interdental Papillae Reconstruction","NOT_YET_RECRUITING","2025-08-18",{"date":90,"type":33},"2025-08-22",{"date":92,"type":20},"2025-09-15",{"date":94,"type":20},"2026-12-30",{"name":39,"class":40},{"id":97,"slug":98,"hasResults":11,"nctId":99,"briefTitle":100,"officialTitle":100,"acronym":101,"eligibilityCriteria":102,"healthyVolunteers":11,"sex":15,"minAge":103,"maxAge":104,"enrollmentInfo":105,"targetDuration":4,"studyType":21,"phases":106,"briefSummary":107,"conditions":108,"keywords":111,"overallStatus":87,"whyStopped":4,"lastUpdateSubmitDate":88,"lastUpdatePostDateStruct":116,"startDateStruct":117,"completionDateStruct":118,"leadSponsor":120,"locationsCount":4},"100594126","evaluation-of-a-novel-lip-bumper-with-integrated-distal-shoe-appliance-in-preventing-second-molar-impaction-in-children-with-anterior-deep-bite-100594126","NCT07015385","Evaluation of a Novel Lip Bumper With Integrated Distal Shoe Appliance in Preventing Second Molar Impaction in Children With Anterior Deep Bite","Novel Lip Bump","Inclusion Criteria:\n\n* Age between 8 and 11 years\n* In mixed dentition stage (presence of permanent first molars and incisors; unerupted second molars)\n* Presence of an anterior deep bite of ≥ 2 mm (measured vertically between upper and lower incisors)\n* Class I or mild Class II malocclusion\n* Good general health with no systemic conditions that may affect dental development or treatment\n* Written informed consent obtained from the parent or legal guardian and assent from the child\n\nExclusion Criteria:\n\n* History of previous orthodontic treatment\n* Presence of craniofacial anomalies (e.g., cleft lip\u002Fpalate) or syndromic conditions\n* Diagnosis of systemic diseases that affect bone metabolism or craniofacial growth (e.g., juvenile rheumatoid arthritis, osteogenesis imperfecta)\n* Evidence of poor oral hygiene or active caries requiring urgent dental care\n* Use of any medication known to affect dental development (e.g., long-term corticosteroids, antiepileptics)\n* Behavioral or developmental disorders that would preclude cooperation with appliance wear or study procedures","8 Years","11 Years",{"count":52,"type":20},[54],"The goal of this clinical trial is to evaluate the effectiveness of a novel lip bumper with an integrated distal shoe in preventing second molar impaction in children aged 8-10 years with anterior open bite during the mixed dentition stage.\n\nThe main questions it aims to answer are:\n\n* Does the integrated distal shoe significantly reduce the risk of second molar impaction compared to conventional lip bumpers?\n* Does the appliance improve anterior open bite correction and influence lower incisor inclination?\n\nResearchers will compare Group I (lip bumper with distal shoe) to Group II (conventional lip bumper) to see if the modified appliance prevents mesial drift of first molars and improves eruption outcomes of second molars.\n\nParticipants will:\n\n* Undergo initial records including panoramic and cephalometric radiographs, study models, and intraoral photos\n* Be fitted with one of the two appliances and followed up every 6 weeks over a 12-month period\n* Receive radiographic and clinical evaluation of second molar eruption\n* Complete assessments related to overbite changes, incisor inclination, comfort, and compliance This trial seeks to inform early orthodontic protocols and may offer a dual-function solution for both molar guidance and open bite correction.",[109,110],"Bite","Orthodontics",[112,113,114,115],"Malocclusion","Angle Class II","Deep Bite","Child",{"date":90,"type":33},{"date":92,"type":20},{"date":119,"type":20},"2026-11",{"name":39,"class":40},""]