[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"David Okonkwo, MD, PhD\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":45},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":17,"sex":18,"minAge":19,"maxAge":20,"enrollmentInfo":21,"targetDuration":4,"studyType":24,"phases":4,"briefSummary":25,"conditions":26,"keywords":28,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":34,"lastUpdatePostDateStruct":35,"startDateStruct":38,"completionDateStruct":40,"leadSponsor":42,"locationsCount":5},"100416894","university-of-pittsburgh-brain-health-initiative-100416894",false,"NCT04708613","University of Pittsburgh Brain Health Initiative","Prevalence of Brain Health Versus Neurodegeneration in Former Professional Football Players","BHI","Inclusion criteria:\n\nFormer professional football player\u002Fexposed group:\n\n1. Professional football retiree aged 29-59\n2. Played a minimum of 3 professional football seasons, with a minimum of 3 games in each season\n3. Fluent in English (translations are not available\u002Fvalidated for most neuropsychological tests)\n\nControl\u002Funexposed group:\n\n1. Age 29-59 male\n2. High school education or beyond\n3. Fluent in English (translations are not available\u002Fvalidated for most neuropsychological tests)\n\nExclusion criteria:\n\nControl\u002Funexposed group:\n\n1. Played organized football beyond high school\n2. History of severe TBI\n3. Current unstable cardiovascular disorder\n\nFor both groups:\n\n1. Prior history of psychosis (such as schizophrenia), or other major neurological disorder that would interfere with testing, in the opinion of the primary investigator.\n2. Contraindication to MR imaging, such as ferrous metal, pacemakers, or concerns about claustrophobia",true,"MALE","29 Years","59 Years",{"count":22,"type":23},300,"ESTIMATED","OBSERVATIONAL","This project will define the prevalence of brain health (i.e., normal cognitive, neuromotor, behavioral function) in living professional football retirees and group-matched controls through a comprehensive assessment of clinical, neuroimaging, and biomarker measures.",[27],"Traumatic Brain Injury",[29,30,31,32],"Brain Health","Football","Contact Sport","Concussion","RECRUITING","2026-06-17",{"date":36,"type":37},"2026-06-22","ACTUAL",{"date":39,"type":37},"2019-11-18",{"date":41,"type":23},"2026-12",{"name":43,"class":44},"David Okonkwo, MD, PhD","OTHER",""]