[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"De Viersprong\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":78},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,44],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":23,"conditions":24,"keywords":26,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":32,"lastUpdatePostDateStruct":33,"startDateStruct":36,"completionDateStruct":38,"leadSponsor":40,"locationsCount":43},"100518585","effectiveness-of-multisystemic-therapy-for-adolescents-from-families-with-intellectual-disabilities-100518585",false,"NCT06032455","Effectiveness of Multisystemic Therapy for Adolescents From Families With Intellectual Disabilities","The Effectiveness of Multisystemic Therapy for Adolescents With Severe Behavioural Problems From Families With Intellectual Disabilities: A Mixed-Method Study","Referral Criteria:\n\n* Known or suspected ID of the referred adolescent and\u002For their parent(s);\n* Educational level of the referred adolescent and\u002For highest attained diploma of their parent(s) is indicative of potential ID.\n\nInclusion Criteria Study Sample:\n\n* Adolescent must be 10 to 19 years old at the start of treatment;\n* Adolescent presents with severe behavioural problems in at least two life areas;\n* Adolescent lives with a family or there is a family the adolescent can live with, in which parent(s) have parental custody for a longer period of time;\n* Parent(s) consent(s) and is\u002Fare willing to engage in treatment to prevent an out-of-home placement of the adolescent;\n* Adolescent and\u002For parent(s) have a known or suspected intellectual disability (operationalised as an intelligence quotient \\[IQ\\] score of between 50-85 and additional deficits in adaptive functioning)\n* Adolescent and\u002For parent(s) have sufficient knowledge of the Dutch language (as assessed by a clinician and\u002For researcher) in order to understand and answer the various (self-report) questionnaires.\n\nExclusion Criteria Study Participation:\n\n* Adolescent lives independently;\n* Adolescent presents with severe problematic sexual behaviours, without presenting with other severe behavioural problems;\n* Adolescent presents suicidal, psychotic, or homicidal requiring specialised treatment (such as a crisis placement in a residential facility);\n* Adolescent has a severe Autism Spectrum Disorder (level 2-3 according to the Diagnostic and Statistical Manual of Mental Disorders \\[DSM-V\\] criteria) or a severe ID (IQ score \\\u003C50);\n* Adolescent has internalising psychiatric problems which are the primary reason for referral, or has serious psychiatric problems (similar to #3 as well as for example eating disorder.","ALL","10 Years","19 Years",{"count":20,"type":21},470,"ESTIMATED","OBSERVATIONAL","The goal of this observational study is to determine the effectiveness of a specialisation of multisystemic therapy (MST) for adolescents with severe behavioural problems from families with an intellectual disability (ID; MST-ID).\n\nTo achieve this goal, a mixed method study design is used. To this end, a quantitative and a qualitatively primary research question are formulated:\n\n* Is MST-ID superior, when compared to standard MST, in reducing rule-breaking behaviour of adolescents (quantitative)?\n* What are the experiences of adolescents and\u002For parents receiving MST-ID treatment (qualitative)?\n\nParticipants will be asked to complete two screeners (questionnaires delivered as a verbal interview) with a total duration of approximately 30 minutes. Other data will be collected through Routine Outcome Monitoring questionnaires that are part of standard MST procedures. To this end, five 'time points' have been identified: T0 (start of MST\\[-ID\\] treatment), T1 (end of MST\\[-ID\\] treatment), T2 (follow-up 6 month after MST\\[-ID\\] treatment), T3 (follow-up 12 month after MST\\[-ID\\] treatment), and T4 (follow-up 18 month after MST\\[-ID\\] treatment). The qualitative method used to gain insight into families' experiences is determined in consultation with the families.\n\nTo assess the effectiveness of MST-ID, its treatment outcomes will be compared to standard MST treatment outcomes of families with ID.",[25],"Behavioural Problems",[27,28,29,30],"multisystemic therapy","intellectual disability","adolescent behavioural problems","family functioning","RECRUITING","2026-04-08",{"date":34,"type":35},"2026-04-13","ACTUAL",{"date":37,"type":35},"2023-09-04",{"date":39,"type":21},"2027-09",{"name":41,"class":42},"De Viersprong","OTHER",4,{"id":45,"slug":46,"hasResults":11,"nctId":47,"briefTitle":48,"officialTitle":49,"acronym":50,"eligibilityCriteria":51,"healthyVolunteers":11,"sex":16,"minAge":52,"maxAge":4,"enrollmentInfo":53,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":55,"conditions":56,"keywords":58,"overallStatus":70,"whyStopped":4,"lastUpdateSubmitDate":71,"lastUpdatePostDateStruct":72,"startDateStruct":73,"completionDateStruct":75,"leadSponsor":77,"locationsCount":5},"100632094","long-term-follow-up-of-mentalization-based-treatment-exploring-variability-in-outcomes-long-term-value-and-experiences-10-year-after-receiving-mbt-day-hospital-or-mbt-intensive-outpatient-100632094","NCT07509216","Long Term Follow-up of Mentalization-Based Treatment: Exploring Variability in Outcomes, Long-term Value and Experiences 10+ Year After Receiving MBT Day Hospital or MBT Intensive Outpatient","MBT-EVOLVE: Mentalization-Based Treatment: Exploring Variability in Outcomes, Long-term Value and Experiences: A 10+ Year Follow-up of Two Types of MBT for BPD - Quantitative and Qualitative Perspectives on Long-term Functioning","MBT-EVOLVE","Inclusion Criteria:\n\n* Participation in the original randomized controlled trial of mentalization-based treatment (MBT-DH versus MBT-IOP)\n* Did not decline to be contacted for future research\n* Able to provide informed consent at the time of the long-term follow-up assessment\n\n(No separate exclusion criteria are specified, as exclusion follows directly from these inclusion criteria.)","18 Years",{"count":54,"type":21},113,"This study is a long-term follow-up study of a previous multicenter randomized controlled trial, in which n=114 participants were included. This RCT compared the effectiveness of two intensities of mentalisation-based treatment (MBT) for individuals with borderline personality disorder (BPD).\n\nThe goal of this study is to learn how people who received MBT in the past for BPD are doing more than 10 years later. MBT is a type of psychotherapy that helps people understand and manage their thoughts and feelings, and supports improvements in identity and relationships, with the aim of improving daily life functioning.\n\nThe main questions this study aims to answer are:\n\n1. How are people who received MBT in the past functioning more than 10 years later, and how is their use of mental health care and associated costs at this point in their lives?\n2. Do long-term outcomes differ between people who received day-hospital MBT and people who received intensive outpatient MBT, and are these outcomes influenced by how much time has passed since treatment ended or by clinical characteristics from the past, such as symptom severity, trauma history, or level of mentalizing?\n3. How do people who received MBT experience its impact on their symptoms, daily life, and relationships both during treatment and in the years afterward, including the impact of treatment intensity?\n\nParticipants will:\n\n* Fill in online questionnaires about symptoms, relationships, health, and daily functioning (about 60 minutes).\n* Take part in a short interview to check whether BPD symptoms are still present (about 20 minutes).\n* A smaller group will be invited for a longer semi-structured qualitative interview (about 60 minutes) to talk about their personal experiences with MBT and what has impacted their life after treatment.\n\nThere are no new treatments in this study. All participants completed MBT many years ago. Participation happens online or in person based on personal preference.",[57],"Borderline Personality Disorder",[59,60,61,62,63,64,65,66,67,68,69],"mentalisation-based treatment","health care utilization","long-term follow-up","borderline personality disorder","psychosocial functioning","recovery","patient-reported outcomes","patient experiences","mixed-methods","qualitative research","health care costs","NOT_YET_RECRUITING","2026-04-03",{"date":32,"type":35},{"date":74,"type":21},"2026-04-02",{"date":76,"type":21},"2027-06",{"name":41,"class":42},""]