[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Desmond Tutu TB Centre\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":45},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":4,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":23,"conditions":24,"keywords":27,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":33,"lastUpdatePostDateStruct":34,"startDateStruct":37,"completionDateStruct":39,"leadSponsor":41,"locationsCount":44},"100585425","to-evaluate-mucosal-and-systematic-immune-response-to-acute-respiratory-tract-infections-of-south-african-children-100585425",false,"NCT06902194","To Evaluate Mucosal and Systematic Immune Response to Acute Respiratory Tract Infections of South African Children","Mucosal Surveillance and Immunology of Respiratory Pathogens in South African Children Post the COVID-19 Pandemic","Muco-Kids","Inclusion Criteria:\n\n\\- Children aged 0-13 years with acute respiratory tract infections presenting to Tygerberg Hospital (TBH) in Cape Town, South Africa, for routine care\n\nExclusion Criteria:\n\n* Admitted for \\\u003C 72 hours","ALL","13 Years",{"count":20,"type":21},250,"ESTIMATED","OBSERVATIONAL","The goal of this observational study is to answer a few questions about respiratory tract infections in South African children:\n\n1. How do children with COVID-19 and other respiratory (chest, throat, ear or nose) germs show symptoms? What signs should be looked for, and which children are more likely to get seriously ill? Are there any new germs that haven't been discovered yet? Can immune cells in saliva predict which children will get more severe disease?\n2. The body's immune response (soldier- cells) in blood and saliva (spit) will be studied.\n3. What is the short-term effect of COVID-19 and other respiratory viruses\u002F germs on the breathing (lung function) of children?\n4. What is the impact of respiratory germs on the quality of life in children and their families? The investigators aim to recruit a minimum of 250 children with respiratory pathogens.",[25,26],"Respiratory Tract Infections (RTI)","Mucosal Immunity",[28,29,30,31],"Mucosal immunity","Mucosal immunology","Respiratory tract infections","Saliva","RECRUITING","2025-03-28",{"date":35,"type":36},"2025-03-30","ACTUAL",{"date":38,"type":36},"2024-10-23",{"date":40,"type":21},"2025-11",{"name":42,"class":43},"Desmond Tutu TB Centre","OTHER",2,""]