[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Dicle University\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":278},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,10,0,[8,43,68,86,114,144,171,199,232,257],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":23,"conditions":24,"keywords":27,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":31,"lastUpdatePostDateStruct":32,"startDateStruct":35,"completionDateStruct":37,"leadSponsor":39,"locationsCount":42},"100641294","effect-of-preoperative-cimt-on-hemodynamics-during-liver-transplantation-100641294",false,"NCT07660679","Effect of Preoperative CIMT on Hemodynamics During Liver Transplantation","The Effect of Preoperative Carotid Intima-Media Thickness on Intraoperative Hemodynamic Profile in Liver Transplant Patients","CIMT-LIVER","Inclusion Criteria:\n\n* Patients aged between 18 and 65 years\n* Scheduled for elective liver transplantation surgery\n* Completed preoperative carotid intima-media thickness (CIMT) ultrasonographic measurement\n* Patients with signed informed consent for data collection\n\nExclusion Criteria:\n\n* Patients undergoing emergency liver transplantation\n* History of previous carotid artery surgery or stenting\n* Known severe carotid artery stenosis (\\>70%)\n* Severe intraoperative hemodynamic instability prior to induction (e.g., active bleeding or shock)\n* Incomplete intraoperative advanced hemodynamic monitoring data or vasopressor records","ALL","18 Years",{"count":20,"type":21},54,"ESTIMATED","OBSERVATIONAL","Candidates for liver transplantation (CT) carry an increased risk of cardiovascular disease (CVD) due to underlying end-stage liver disease (ESHD) and immunosuppressive drugs used post-transplantation. CVD is a significant cause of long-term mortality after CT \\[1\\] \\[2\\]. Carotid Intima-Media Thickness (CIMT), a subclinical marker of atherosclerosis in the preoperative period, is a non-invasive method used to predict future CVD risk \\[3\\]. High CIMT indicates atherosclerosis and decreased arterial compliance. This can compromise organ perfusion and increase the risk of postoperative complications by increasing intraoperative blood pressure variability (BPV) during anesthesia induction and surgical stress in major surgeries such as CT. Studies investigating whether CIMT is an independent risk factor for perioperative hemodynamic instability in CT patients are limited. The aim of our study is to investigate the effect of CIMT values on intraoperative hemodynamic parameters. Secondary objectives are to determine the association of CIMT with the incidence of hypotension, vasopressor requirement, postoperative acute renal injury (ARI), and major cardiac adverse events (MCAE) after anesthesia induction.\n\nTheoretical Benefit: To make a significant contribution to the literature on the relationship between atherosclerosis and anesthesia management by determining whether CIMT is an independent predictor of perioperative hemodynamic instability in chemotherapy patients.\n\nPractical Benefit: To ensure the inclusion of CIMT measurement in the anesthesia risk assessment of chemotherapy candidates. Identifying patients with high CIMT will guide the implementation of more aggressive and targeted hemodynamic management strategies (e.g., more frequent invasive monitoring, proactive vasopressor use) during anesthesia induction and maintenance.",[25,26],"Liver Transplantation","Carotid Intima-media Thickness",[25,28,29],"Hemodynamics","Preoperative Assessment","RECRUITING","2026-06-18",{"date":33,"type":34},"2026-06-23","ACTUAL",{"date":36,"type":34},"2026-02-11",{"date":38,"type":21},"2026-07-01",{"name":40,"class":41},"Dicle University","OTHER",1,{"id":44,"slug":45,"hasResults":11,"nctId":46,"briefTitle":47,"officialTitle":48,"acronym":4,"eligibilityCriteria":49,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":50,"targetDuration":4,"studyType":52,"phases":53,"briefSummary":55,"conditions":56,"keywords":4,"overallStatus":59,"whyStopped":4,"lastUpdateSubmitDate":60,"lastUpdatePostDateStruct":61,"startDateStruct":63,"completionDateStruct":65,"leadSponsor":67,"locationsCount":42},"100642251","cerebral-oximetry-guided-low-fio2-strategies-in-thoracic-surgery-100642251","NCT07659483","Cerebral Oximetry-Guided Low FiO2 Strategies in Thoracic Surgery.","Safety and Efficacy of Cerebral Oximetry-Guided Low FiO2 Strategies in Thoracic Surgery","Inclusion Criteria:\n\n* Patients aged 18 years or older. Scheduled for elective thoracic surgery requiring one-lung ventilation (OLV). American Society of Anesthesiologists (ASA) Physical Status classification I-III.\n\nExclusion Criteria:\n\n* History of cerebrovascular disease. Left ventricular ejection fraction Pulmonary hypertension. Interstitial lung disease.\n\nRenal failure. Neuromuscular disease. Pregnancy. Expected OLV duration less than 30 minutes (\\\u003C 30 min)",{"count":51,"type":21},60,"INTERVENTIONAL",[54],"NA","Brief Summary (Kısa Özet)The purpose of this study is to evaluate the safety and efficacy of a cerebral oximetry-guided low fraction of inspired oxygen (FiO\\_2) ventilation strategy compared to a standard high FiO\\_2 strategy in patients undergoing elective thoracic surgery requiring one-lung ventilation (OLV).Oxygen toxicity and related postoperative pulmonary complications remain significant risks during thoracic anesthesia. While standard protocols often rely on high inspired oxygen concentrations to maintain peripheral oxygen saturation (SpO\\_2), this approach may induce hyperoxia. Conversely, lowering FiO\\_2 arbitrarily can increase the risk of hypoxemia or compromise tissue oxygenation. This prospective, parallel-group, 1:1 randomized, single-blind clinical trial aims to safely reduce intraoperative oxygen exposure by using regional cerebral oxygen saturation (rSO\\_2) monitoring as a physiological guide.A total of 60 participants aged 18 and older, classified as ASA I-III and scheduled for elective thoracic surgery, will be randomly assigned to one of two arms:Experimental Group (Guided Low FiO\\_2 Strategy): Ventilation will be initiated at a low FiO\\_2 of 0.5. The FiO\\_2 level will not be increased unless peripheral saturation (SpO\\_2) falls below 90% or cerebral oxygenation (rSO\\_2) drops below 80% of the patient's baseline value.Active Comparator Group (Standard Strategy): Patients will receive conventional anesthesia management, maintaining standard high FiO\\_2 levels to keep SpO\\_2 above 90% without cerebral oximetry guidance.The primary outcomes to be measured are the incidence of cerebral desaturation during the perioperative period and the incidence of postoperative delirium assessed via the 3D-CAM tool until hospital discharge. Secondary outcomes include intraoperative hemodynamic stability, arterial blood gas parameters (PaO\\_2, PaCO\\_2, pH, lactate), incidence of hypoxemia, total one-lung ventilation duration, postoperative cognitive dysfunction (POCD), and lengths of stay in both the intensive care unit (ICU) and the hospital.By utilizing real-time non-invasive cerebral oximetry, the study intends to demonstrate a safe ventilation protocol that minimizes oxygen toxicity without compromising cerebral oxygenation or clinical recovery outcomes.",[57,58],"Thoracic Surgery","Anesthesia","NOT_YET_RECRUITING","2026-06-16",{"date":62,"type":34},"2026-06-22",{"date":64,"type":21},"2026-06-15",{"date":66,"type":21},"2026-08-15",{"name":40,"class":41},{"id":69,"slug":70,"hasResults":11,"nctId":71,"briefTitle":72,"officialTitle":73,"acronym":4,"eligibilityCriteria":74,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":75,"targetDuration":4,"studyType":52,"phases":76,"briefSummary":77,"conditions":78,"keywords":4,"overallStatus":59,"whyStopped":4,"lastUpdateSubmitDate":60,"lastUpdatePostDateStruct":80,"startDateStruct":81,"completionDateStruct":83,"leadSponsor":85,"locationsCount":42},"100642156","remifentanil-monotherapy-vs-remifentanil-nicardipine-for-controlled-hypotension-in-otolaryngological-surgery-100642156","NCT07659496","Remifentanil Monotherapy vs. Remifentanil-Nicardipine for Controlled Hypotension in Otolaryngological Surgery","The Effects of Remifentanil Monotherapy Versus Remifentanil-Nicardipine Combination on Advanced Hemodynamic Parameters for Controlled Hypotension During Otolaryngological Surgery","Inclusion Criteria:\n\n* Patients aged \\> 18 years\n* American Society of Anesthesiologists (ASA) physical status I-II\n* Scheduled to undergo otolaryngological surgery under general anesthesia\n* Provision of written informed consent\n\nExclusion Criteria:\n\n* Aged \\\u003C 18 years\n* ASA physical status III or higher\n* Known severe cardiovascular (coronary artery disease, heart failure, uncontrolled hypertension), respiratory, renal, or hepatic disease\n* Known allergy to the study drugs (remifentanil, nicardipine)\n* Chronic use of beta-blockers, calcium channel blockers, or any other medication affecting blood pressure\n* Pregnancy or breastfeeding\n* Morbid obesity\n* Emergency surgery requirement\n* Refusal to participate in the study",{"count":51,"type":21},[54],"Controlled hypotension is a widely employed technique in otolaryngological (ear, nose, and throat) surgery, primarily aimed at improving surgical field visibility and minimizing intraoperative blood loss. By maintaining mean arterial pressure within a targeted range, this approach facilitates a clearer operative field, reduces the need for blood transfusion, and shortens operative time, thereby contributing to improved surgical outcomes.\n\nAmong the pharmacological agents used to achieve controlled hypotension, remifentanil - an ultra-short-acting synthetic opioid - has gained widespread acceptance due to its rapid onset, predictable offset, and favorable hemodynamic profile. Nicardipine, a second-generation dihydropyridine calcium channel blocker, is also utilized for its potent vasodilatory properties and titratable antihypertensive effect. When used in combination, these two agents may offer complementary mechanisms of action; however, their combined impact on advanced hemodynamic parameters remains insufficiently characterized in the otolaryngological surgical setting.\n\nThe primary aim of this study is to compare the effects of remifentanil monotherapy versus remifentanil-nicardipine combination therapy on advanced hemodynamic parameters, cardiac physiology, and tissue perfusion in patients undergoing controlled hypotension during otolaryngological surgery. Advanced hemodynamic monitoring - including parameters such as cardiac output, stroke volume, systemic vascular resistance, and oxygen delivery indices - will provide a more comprehensive physiological assessment beyond conventional blood pressure measurements.\n\nAs secondary objectives, this study will evaluate and compare both regimens with respect to surgical field quality, surgeon satisfaction, intraoperative hemodynamic stability, and perioperative adverse effects. It is anticipated that a thorough comparative analysis of these two approaches will contribute to evidence-based anesthetic decision-making and help optimize patient safety and surgical outcomes in otolaryngological procedures.",[79,58],"Otolaryngological Surgery",{"date":62,"type":34},{"date":82,"type":21},"2026-06-30",{"date":84,"type":21},"2026-08-30",{"name":40,"class":41},{"id":87,"slug":88,"hasResults":11,"nctId":89,"briefTitle":90,"officialTitle":91,"acronym":92,"eligibilityCriteria":93,"healthyVolunteers":94,"sex":17,"minAge":4,"maxAge":4,"enrollmentInfo":95,"targetDuration":4,"studyType":52,"phases":96,"briefSummary":97,"conditions":98,"keywords":101,"overallStatus":59,"whyStopped":4,"lastUpdateSubmitDate":106,"lastUpdatePostDateStruct":107,"startDateStruct":109,"completionDateStruct":111,"leadSponsor":113,"locationsCount":4},"100632865","forensic-nursing-education-for-pediatric-nurses-a-randomized-controlled-trial-100632865","NCT07519239","Forensic Nursing Education for Pediatric Nurses: A Randomized Controlled Trial","Forensic Nursing Education in Pediatric Nurses: A Randomized Controlled Trial","FORENSIC-NURSE","Inclusion Criteria:\n\n* Inclusion Criteria:\n* Nurses working in pediatric clinics, pediatric emergency, or pediatric intensive care units\n* Voluntary participation in the study\n* Working actively during the data collection period\n* Agreeing to participate in the study\n\nExclusion Criteria:\n\n* Nurses who are on leave during the study period\n* Nurses who previously received forensic nursing training\n* Nurses who do not complete the training program\n* Nurses who withdraw from the study\n\nExclusion Criteria:\n\n\\-",true,{"count":51,"type":21},[54],"This randomized controlled trial aims to evaluate the effect of structured forensic nursing education on pediatric nurses' forensic competency. Nurses working in pediatric clinics, pediatric emergency, and pediatric intensive care units will be randomly assigned to intervention and control groups. The intervention group will receive a four-week structured forensic nursing education program supported by case scenarios and educational brochures. The control group will receive no intervention during the study period. Data will be collected using a Personal Information Form and the Forensic Nursing Task Competency Scale at baseline, immediately after the intervention, and three months after the training. The findings are expected to improve pediatric nurses' knowledge, skills, and responsibilities in managing forensic cases.",[99,100],"Forensic Nursing Education in Pediatric Nurses","Forensic Competency Training",[102,103,104,105],"Forensic nursing","Pediatric nurses","Education intervention","Forensic cases","2026-04-02",{"date":108,"type":34},"2026-04-09",{"date":110,"type":21},"2026-06-01",{"date":112,"type":21},"2026-10-01",{"name":40,"class":41},{"id":115,"slug":116,"hasResults":11,"nctId":117,"briefTitle":118,"officialTitle":119,"acronym":120,"eligibilityCriteria":121,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":122,"enrollmentInfo":123,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":125,"conditions":126,"keywords":129,"overallStatus":59,"whyStopped":4,"lastUpdateSubmitDate":136,"lastUpdatePostDateStruct":137,"startDateStruct":139,"completionDateStruct":141,"leadSponsor":143,"locationsCount":4},"100632539","lung-ultrasound-score-and-postoperative-pulmonary-complications-in-major-non-thoracic-surgery-100632539","NCT07515001","Lung Ultrasound Score and Postoperative Pulmonary Complications in Major Non-Thoracic Surgery","Predictive Value of Perioperative Lung Ultrasound Score for Early Postoperative Oxygen Requirement and Pulmonary Complications in Patients Undergoing Major Non-Thoracic Surgery","LUS-POSTOP","Inclusion Criteria:\n\n* Aged 18 to 65 years\n* Scheduled for elective major non-thoracic surgery\n* Undergoing surgery under general anesthesia\n* Expected surgical duration of 3 hours or longer\n* ASA physical status I-III\n* Willing to participate in the study\n* Provides written informed consent\n\nExclusion Criteria:\n\n* Patients undergoing thoracic or cardiac surgery\n* Advanced chronic lung disease (e.g., severe COPD or pulmonary fibrosis)\n* History of previous lung resection\n* Preoperative pneumonia or active pulmonary infection\n* Body mass index greater than or equal to 40 kg\u002Fm2\n* Pregnancy\n* Emergency surgery\n* Planned postoperative mechanical ventilation or intensive care unit admission\n* Refusal to participate in the study","65 Years",{"count":124,"type":21},97,"This prospective observational cohort study aims to evaluate the predictive value of perioperative lung ultrasound (LUS) score in determining early postoperative oxygen requirement and pulmonary complications in patients undergoing major non-thoracic surgery. Postoperative pulmonary complications remain a significant cause of morbidity and mortality in surgical patients. Lung ultrasound is a non-invasive, bedside imaging modality that allows real-time assessment of lung aeration and pathology. This study will investigate the association between perioperative LUS score and early postoperative respiratory outcomes, including oxygen requirement and pulmonary complications.",[127,128],"Postoperative Pulmonary Complications (PPCs)","Hypoxemia",[130,131,132,133,134,135,58],"lung ultrasound","Lus Score","Perioperative Ultrasound","Postoperative Complications","Oxygen Requirement","Non-Thoracic Surgery","2026-03-31",{"date":138,"type":34},"2026-04-07",{"date":140,"type":21},"2026-04",{"date":142,"type":21},"2027-01",{"name":40,"class":41},{"id":145,"slug":146,"hasResults":11,"nctId":147,"briefTitle":148,"officialTitle":149,"acronym":150,"eligibilityCriteria":151,"healthyVolunteers":94,"sex":17,"minAge":152,"maxAge":153,"enrollmentInfo":154,"targetDuration":4,"studyType":52,"phases":156,"briefSummary":157,"conditions":158,"keywords":161,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":163,"lastUpdatePostDateStruct":164,"startDateStruct":166,"completionDateStruct":168,"leadSponsor":170,"locationsCount":42},"100628494","the-effect-of-a-kaleidoscope-and-cartoons-for-dental-treatment-in-children-100628494","NCT07462364","The Effect of a Kaleidoscope and Cartoons for Dental Treatment in Children","The Effect of a Kaleidoscope and Cartoons on Pain and Anxiety Associated With Local Anesthetic Injection for Dental Treatment in Children","Pain","Inclusion Criteria:\n\n* Children aged between 7 and 12 years\n* Children requiring local infiltration anesthesia for dental treatment\n* Children who apply to the Pediatric Dentistry Clinic of Dicle University Faculty of Dentistry\n* Children and their parents who voluntarily agree to participate in the study and provide informed consent\n* Children with positive or definitely positive behavior according to the Frankl Behavior Rating Scale\n\nExclusion Criteria:\n\n* Children with chronic diseases\n* Children with a history of hospitalization or surgery\n* Children with neurological or behavioral disorders such as autism, attention deficit hyperactivity disorder (ADHD), or learning disabilities\n* Children with mental retardation, hearing impairment, or speech problems\n* Children with dental abscesses or fistulas","7 Years","12 Years",{"count":155,"type":21},126,[54],"Dental fear and anxiety are among the most common challenges encountered in pediatric dental practice and may negatively affect children's cooperation and acceptance of dental treatment. Local anesthesia injections are considered one of the main sources of pain and anxiety during dental procedures in children. Although pharmacological methods can be effective in managing pain and anxiety, they may not always be preferred due to potential side effects, limited applicability, and the possibility of increasing stress in children. Therefore, non-pharmacological behavioral management techniques, particularly distraction methods, are increasingly used in pediatric dentistry to reduce pain perception and anxiety.\n\nThe aim of this randomized controlled trial is to evaluate the effects of kaleidoscope use and cartoon distraction on pain, fear, and anxiety associated with local anesthesia injections in children undergoing dental treatment. The study will be conducted at the Department of Pediatric Dentistry, Faculty of Dentistry, Dicle University. A total of 126 children aged between 7 and 12 years who require local infiltration anesthesia during dental treatment will be included in the study. Participants will be randomly assigned to one of three groups: the Kaleidoscope Group, the Cartoon Distraction Group, or the Control Group. Children in the kaleidoscope group will use a kaleidoscope during the local anesthesia injection, while children in the cartoon group will watch cartoons during the procedure. In the control group, local anesthesia will be administered according to the routine clinical procedure without any distraction technique.\n\nPain, fear, and anxiety levels will be assessed using the Wong-Baker FACES Pain Rating Scale, the Children's Fear Scale, and the Children's Anxiety Scale-State. Behavioral responses will also be evaluated using the Frankl Behavior Rating Scale. The findings of this study are expected to provide evidence regarding the effectiveness of simple and non-pharmacological distraction techniques in reducing pain and anxiety associated with local anesthesia injections in pediatric dental patients.",[159,160,150],"Dental Anxiety","Dental Fear",[162],"Dental anxiety, dental fear, pain, local anesthesia, children","2026-03-11",{"date":165,"type":34},"2026-03-13",{"date":167,"type":34},"2026-03-10",{"date":169,"type":21},"2026-05-10",{"name":40,"class":41},{"id":172,"slug":173,"hasResults":11,"nctId":174,"briefTitle":175,"officialTitle":176,"acronym":4,"eligibilityCriteria":177,"healthyVolunteers":94,"sex":17,"minAge":152,"maxAge":178,"enrollmentInfo":179,"targetDuration":4,"studyType":52,"phases":181,"briefSummary":182,"conditions":183,"keywords":187,"overallStatus":59,"whyStopped":4,"lastUpdateSubmitDate":191,"lastUpdatePostDateStruct":192,"startDateStruct":194,"completionDateStruct":196,"leadSponsor":198,"locationsCount":42},"100604974","pain-and-anxiety-in-pediatric-dentistry-computer-controlled-vs-traditional-anesthesia-100604974","NCT07156487","Pain and Anxiety in Pediatric Dentistry: Computer-Controlled vs. Traditional Anesthesia","The Evaluation of the Effects of Computer-controlled Electronic Anesthesia Systems and Traditional Local Anesthesia Techniques, Along With Different Anesthetic Agents, on Pain and Anxiety Levels During Dental Treatments in Pediatric Patients: A Randomized Controlled Clinical Study","Inclusion Criteria:\n\n* Patients classified as ASA I in general systemic health\n\n  * Children between 7 and 10 years of age\n  * Absence of any syndromic condition\n  * No physical or mental disability\n  * No prior dental treatment experience\n  * Frankl Behavior Rating Scale Class III or IV\n  * Presence of carious lesions limited to less than one-third of the buccolingual distance between cusp tips on the occlusal surfaces of primary or permanent molars on both sides\n  * Radiographic evidence of caries involving up to half of the dentin thickness with intact dentin at the pulp-dentin border in primary or permanent molars on both sides\n  * Teeth on both sides responding positively to pulp vitality tests, with no periradicular pathology or significant widening of the lamina dura on periapical radiographs\n\nExclusion Criteria:\n\n* Patients with mild or severe systemic diseases or those undergoing medical treatment\n\n  * Patients younger than 7 or older than 10 years of age\n  * Uncooperative or noncompliant patients classified as Class I or Class II according to the Frankl Behavior Rating Scale\n  * Patients requiring urgent dental treatment\n  * Patients with wide carious lesions extending beyond one-third of the buccolingual distance between cusp tips on the occlusal surfaces\n  * Patients with carious lesions limited to less than one-third of the buccolingual width only on one side of the jaw\n  * Teeth with carious lesions not reaching half of the dentin thickness on radiographic evaluation or lacking intact dentin at the pulp border\n  * Teeth that do not respond positively to pulp vitality tests, or that show periradicular lesions or marked widening of the lamina dura on periapical radiographs","10 Years",{"count":180,"type":21},84,[54],"The purpose of this clinical study is to evaluate how different local anesthesia techniques affect pain and anxiety levels in children undergoing dental treatment. Specifically, the study compares traditional syringe-based anesthesia with a computer-controlled local anesthesia system.\n\nThe study seeks to answer the following question: Which combination of anesthesia technique is most effective in reducing pain and anxiety in pediatric dental patients?\n\nBy understanding the impact of these variables, the study aims to help dental professionals choose the most appropriate anesthesia approach to improve the comfort and emotional well-being of children during dental procedures.",[184,185,159,186],"Traditional Local Anesthesia","Computer-controlled Electronic Anesthesia","Anxiety in Children",[188,189,190],"Pediatric Dentistry","Injections, Intraosseous","Dental Instruments","2025-09-01",{"date":193,"type":34},"2025-09-05",{"date":195,"type":21},"2025-10",{"date":197,"type":21},"2026-03",{"name":40,"class":41},{"id":200,"slug":201,"hasResults":11,"nctId":202,"briefTitle":203,"officialTitle":204,"acronym":4,"eligibilityCriteria":205,"healthyVolunteers":11,"sex":17,"minAge":206,"maxAge":207,"enrollmentInfo":208,"targetDuration":4,"studyType":52,"phases":210,"briefSummary":211,"conditions":212,"keywords":218,"overallStatus":59,"whyStopped":4,"lastUpdateSubmitDate":224,"lastUpdatePostDateStruct":225,"startDateStruct":227,"completionDateStruct":229,"leadSponsor":231,"locationsCount":42},"100576842","music-effect-on-the-self-injection-testing-fear-and-pain-100576842","NCT06790550","Music Effect on the Self-Injection, Testing Fear and Pain","Examination of Music's Demonstration to Self-Injection, Fear of Testing and Pain in Patients With Type 2 Diabetes","Inclusion Criteria:\n\n* Type 2 diabetes for at least one year\n* Self-administering insulin injection\n* Self-administering glucometer, insulin pen or insulin pump\n\nExclusion Criteria:\n\n* poor mental health\n* Having gestational diabetes mellitus or Type 1 diabetes\n* no hearing problems","15 Years","75 Years",{"count":209,"type":21},100,[54],"Diabetes is a chronic and broad-spectrum metabolic disorder characterized by hyperglycemia that occurs due to relative or absolute insulin deficiency or \"insulin resistance\" developed against insulin action in peripheral tissues, affecting many organs and causing multisystem involvement. Metabolic function continues to deteriorate after diagnosis, leading to worsening glycemic control and insulin therapy becoming necessary. However, patients may have difficulty adhering to insulin therapy. Fears about injections are common in both adults and children and, as research shows, are a major reason why people with diabetes avoid taking insulin. Addressing these fears is an important part of helping patients reduce their risk of diabetes-related complications. Helping patients manage their replacement pain may help reduce the effects of needle fear in the future. There are a number of strategies that can ease the pain.The use of music in pain management has advantages such as being reliable, cheap, and having no side effects, as well as reducing postoperative pain reports. Music distracts the individual from negative stimuli and allows them to focus on something they enjoy, thus reducing pain and anxiety. Music therapy has also been shown to have sedative-protective effects and reduce stress hormone levels. Listening to preferred music can distract and reduce the pain and negative emotions associated with an unpleasant experience.",[213,214,215,150,216,217],"Type 2 Diabetes Mellitus (T2DM)","Insulin","Fear","Injection","Music Therapy",[219,214,220,221,222,223],"type 2 diabetes mellitus","fear","pain","insulin injection","music","2025-01-24",{"date":226,"type":34},"2025-01-28",{"date":228,"type":21},"2025-01-30",{"date":230,"type":21},"2025-07-30",{"name":40,"class":41},{"id":233,"slug":234,"hasResults":11,"nctId":235,"briefTitle":236,"officialTitle":237,"acronym":4,"eligibilityCriteria":238,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":207,"enrollmentInfo":239,"targetDuration":4,"studyType":52,"phases":240,"briefSummary":241,"conditions":242,"keywords":246,"overallStatus":59,"whyStopped":4,"lastUpdateSubmitDate":224,"lastUpdatePostDateStruct":250,"startDateStruct":252,"completionDateStruct":254,"leadSponsor":256,"locationsCount":42},"100577026","investigation-of-the-effect-of-using-curtain-100577026","NCT06792942","Investigation of the Effect of Using \"Curtain\"","Investigation of the Effect of Using \"Curtain\" as a Distraction Method on Fear, Anxiety and Pain in Diagnostic Procedures Performed in Patients With Suspected Thyroid Mass","Inclusion Criteria:\n\n* Suspicion of a mass in the thyroid\n* No vision problems\n\nExclusion Criteria:\n\n* Mental health problems",{"count":209,"type":21},[54],"Thyroid nodules are among the common health problems in adulthood. Thyroid cancers account for approximately 1% of all malignancies in a year.The majority of cancers are diagnosed by thyroid fine needle aspiration biopsy. The most commonly diagnosed cancer type is papillary thyroid cancer and accounts for 85% of all thyroid cancers.Thyroid Ultrasonography is the most important imaging method used in the evaluation of the thyroid gland and its nodules. It enables the detection of nodules and their characteristics and plays a role in deciding which nodules should be evaluated with fine needle aspiration biopsy.Non-pharmacological treatment methods are interventions that can be used to reduce the side effects of medical, surgical or pharmacological treatments. By using medical treatment and complementary therapy together, nurses can reduce patients' anxiety, support their sleep, create a healing environment and increase their health level.\n\nAs a non-pharmacological strategy, distraction can be seen as a cost-effective approach to reduce anxiety in procedures that would cause negative anxiety and increase the opportunity for ease of operation. The curtain method also typically involves the use of visually interesting curtains or partitions that can be drawn around the patient's examination area. These curtains may have calming images or vibrant patterns that can help shift the patient's focus away from the frightening procedure being performed.",[243,244,245],"Ultrasound Therapy; Complications","Fine Needle Aspiration Biopsy","Thyroid Nodule (Diagnosis)",[247,243,248,249],"The curtain","Ultrasound","Thyroid Nodule",{"date":251,"type":34},"2025-01-27",{"date":253,"type":21},"2025-03-01",{"date":255,"type":21},"2025-09-30",{"name":40,"class":41},{"id":258,"slug":259,"hasResults":11,"nctId":260,"briefTitle":261,"officialTitle":262,"acronym":4,"eligibilityCriteria":263,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":207,"enrollmentInfo":264,"targetDuration":4,"studyType":52,"phases":265,"briefSummary":266,"conditions":267,"keywords":270,"overallStatus":59,"whyStopped":4,"lastUpdateSubmitDate":224,"lastUpdatePostDateStruct":272,"startDateStruct":273,"completionDateStruct":275,"leadSponsor":277,"locationsCount":42},"100577025","the-effect-of-virtual-reality-applications-100577025","NCT06792929","The Effect of Virtual Reality Applications","The Effect of Virtual Reality Applications on Diagnostic Procedures Performed in Patients With Suspicious Thyroid Cancer","Inclusion Criteria:\n\n* Patients with suspected thyroid mass\n* No dizziness problem\n* No vision problems\n\nExclusion Criteria:\n\n* Mental health problems that may prevent wearing virtual reality glasses",{"count":209,"type":21},[54],"Thyroid nodules are a common health problem in the adult population. The majority of cancers are diagnosed by thyroid fine needle aspiration biopsy. Thyroid nodules generally show clinical findings in 1-5% of cases on physical examination and 20-70% on ultrasound examination. In diagnosis; Ultrasonography, fine needle aspiration biopsy, ultrasonography-guided fine needle aspiration biopsy, scintigraphy, computed tomography and magnetic resonance imaging are widely used. The fact that the thyroid fine needle aspiration biopsy procedure is painful, there is no speaking or coughing during the procedure, and in case of insufficient sample, the procedure must be performed several times. Its repetition causes fear and anxiety in patients. A combination of pharmacological and nonpharmacological methods for pain control likely provides the most effective pain relief for the patient. Distraction is one of the non-pharmacological methods used in pain control. Distraction is one of the most preferred methods to reduce pain in patients during diagnosis and treatment procedures. It is a method that allows patients to control and reduce the symptoms they experience by focusing their attention on a different point.The aim of this study is to examine the effect of using a motivational video with virtual reality glasses to distract attention during the biopsy procedure on pain, stress and fear in individuals with suspected thyroid cancer.",[268,269,248,244,245],"Thyroid Cancer","Virtual Reality Therapy",[268,269,248,249,271],"Fine needle aspiration biopsy",{"date":251,"type":34},{"date":274,"type":21},"2025-02-25",{"date":276,"type":21},"2025-08-30",{"name":40,"class":41},""]