[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Dijklander Ziekenhuis\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":82},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,50],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":4,"briefSummary":24,"conditions":25,"keywords":27,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":38,"lastUpdatePostDateStruct":39,"startDateStruct":42,"completionDateStruct":44,"leadSponsor":46,"locationsCount":49},"100525898","the-effects-of-surgical-wait-time-for-knee-arthroplasty-quality-of-life-in-patients-awaiting-knee-arthroplasty-100525898",false,"NCT06127719","The Effects of Surgical Wait Time for Knee Arthroplasty Quality of Life in Patients Awaiting Knee Arthroplasty","The Effects of Surgical Wait Time on Function, Pain and Health Related Quality of Life in Patients Awaiting Knee Arthroplasty: a Prospective Multicenter Cohort Study","SIT'NWAIT","Inclusion Criteria:\n\n* on the waiting list for partial or total knee arthroplasty\n* written informed consent\n\nExclusion Criteria:\n\n* none","ALL","18 Years","100 Years",{"count":21,"type":22},150,"ESTIMATED","OBSERVATIONAL","This study prospectively evaluates the effect of surgical wait time on knee function, pain and quality of life in patients waiting for knee arthroplasty (TKA or PKA)",[26],"Knee Osteoarthritis",[28,29,30,31,32,33,34,35,36],"knee arthroplasty","surgical waiting time","waiting list","knee pain","total knee arthroplasy","partial knee arthroplasty","knee function","quality of life","Osteoarthritis","RECRUITING","2023-12-11",{"date":40,"type":41},"2023-12-18","ACTUAL",{"date":43,"type":41},"2023-12-01",{"date":45,"type":22},"2027-12",{"name":47,"class":48},"Dijklander Ziekenhuis","OTHER",1,{"id":51,"slug":52,"hasResults":11,"nctId":53,"briefTitle":54,"officialTitle":55,"acronym":56,"eligibilityCriteria":57,"healthyVolunteers":11,"sex":17,"minAge":58,"maxAge":59,"enrollmentInfo":60,"targetDuration":4,"studyType":62,"phases":63,"briefSummary":65,"conditions":66,"keywords":69,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":74,"lastUpdatePostDateStruct":75,"startDateStruct":77,"completionDateStruct":79,"leadSponsor":81,"locationsCount":5},"100523359","rfa-or-chemical-neurolysis-of-the-genicular-nerves-compared-to-conservative-treatment-for-knee-pain-caused-by-oa-100523359","NCT06094660","RFA or Chemical Neurolysis of the Genicular Nerves Compared to Conservative Treatment for Knee Pain Caused by OA","Patients With Knee Pain Caused by Osteoarthritis: Comparison of Conservative Medical Management With RadioFrequency Ablation or Chemical Neurolysis of the Genicular Nerves With Phenol","RADIOPHENOL","Inclusion Criteria:\n\n1. Adult patients of both sexes, \\>35 years who are not a candidate for TKA due to young age, old age, comorbidity or technical reasons.\n2. OKS \\\u003C 30 on a scale from 0 (severe function) to 48 points (satisfactory function).\n3. Continued pain in the target knee that is moderate to severe (defined as NRS ≥ 6 on an 11-point NRS scale) either constantly or with motion despite at least 3 months of conservative treatments. Conservative treatment can include: active physiotherapy, pharmacological treatment of pain (acetaminophen or NSAIDs) and intra-articular corticosteroid infiltration.\n4. Radiologic confirmation of arthritis for the target knee. Defined as the Kellgren Lawrence (KL) score of 2 or more on X-ray or MRI.\n\nExclusion Criteria:\n\n1. Patient with prior ablation of the genicular nerves, prior partial, resurfacing, or TKA of the target knee (residual hardware).\n2. Patient with a history of neurovascular injury or recent trauma of the lower extremities.\n3. Patient with chronic widespread pain.\n4. Polyneuropathy and\u002For radicular pain in the lower extremities.\n5. Patient is currently implanted with a neurostimulator.\n6. Local or systemic infection (bacteraemia).\n7. Uncontrolled immune suppression.\n8. Intra-articular injections (steroids, hyaluronic acid, platelet enriched plasma, stem cell, …) in the target knee within 90 days from randomisation.\n9. Arthroscopic debridement\u002Flavage into the target knee within 180 days from randomisation.\n10. BMI\\\u003C18,5 kg\u002Fm2 and patients with minimal subcutaneous tissue thickness that would not accommodate ablation with phenol or radio frequency (risk of skin burns).\n11. Allergies to products used during the procedure (lidocaine, phenol, contrast dye).\n12. Patients who have a planned TKA in the near future, defined as patients who already have agreed on a date for the TKA procedure.\n13. Patients with psychosocial problems as determined by the investigator.","35 Years","90 Years",{"count":61,"type":22},192,"INTERVENTIONAL",[64],"NA","A randomised controlled triall (RCT) with three parallel arms comparing the functional outcome of chemical ablation with phenol and radiofrequency ablation (RFA) of the genicular nerves with conservative treatment in patients with chronic knee pain caused by osteoarthritis (OA).",[67,68],"Osteo Arthritis Knee","Knee Pain Chronic",[70,71,72,73],"Pain","Thermal ablation","Phenol neurolysis","Genicular nerve","2023-12-04",{"date":76,"type":41},"2023-12-05",{"date":78,"type":41},"2023-11-27",{"date":80,"type":22},"2026-11-01",{"name":47,"class":48},""]