[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":385},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,15,0,[8,42,69,88,111,133,153,176,206,234,259,288,315,337,362],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":4,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":31,"lastUpdatePostDateStruct":32,"startDateStruct":35,"completionDateStruct":37,"leadSponsor":39,"locationsCount":4},"100644563","mechanical-power-during-different-ventilation-modes-in-laparoscopic-surgery-100644563",false,"NCT07670494","Mechanical Power During Different Ventilation Modes in Laparoscopic Surgery","Comparison of Mechanical Power in Pressure-Regulated Volume Control and Volume-Controlled Ventilation Modes During Laparoscopic Cholecystectomy","Inclusion Criteria:\n\n* Patients undergoing elective laparoscopic cholecystectomy surgery.\n* Patients between 18 and 75 years of age.\n* American Society of Anesthesiologists (ASA) physical status I, II or III.\n* Body Mass Index (BMI) between 18.5 and 35 kg\u002Fm².\n* Voluntary written informed consent for participation.\n\nExclusion Criteria:\n\n* History of significant chronic obstructive pulmonary disease (COPD) or asthma.\n* Previous lung resection or major thoracic surgery.\n* Heavy smokers (more than 20 cigarettes per day).\n* Presence of spontaneous breathing effort during mechanical ventilation.\n* Conversion from laparoscopic surgery to open surgery during the procedure.\n* Emergency surgery cases.\n* Known pregnancy.",true,"ALL","18 Years",{"count":20,"type":21},80,"ESTIMATED","INTERVENTIONAL",[24],"NA","This study investigates how different breathing machine (ventilator) settings affect the energy delivered to the lungs during surgery. Mechanical power is a measure of this energy, and high levels can sometimes lead to lung irritation. In clinical practice, a mode called Pressure-Regulated Volume Control (PRVC) is often used because it lowers the \"peak\" pressure in the airways, which is generally thought to be safer. However, doctors have noticed that even though the peak pressure goes down in PRVC mode, the total mechanical power displayed on the monitor might actually increase compared to the standard Volume-Controlled Ventilation (VCV) mode. In this study, patients undergoing gallbladder surgery will be monitored using both ventilation modes in a random order. The researchers will compare the machine-calculated mechanical power for both modes to see if the perceived benefit of lower peak pressure in PRVC actually results in lower overall energy transfer to the lungs.",[27,28,29],"Laparoscopic Cholecystectomy","Mechanical Ventilation","Ventilator-Induced Lung Injury","NOT_YET_RECRUITING","2026-06-26",{"date":33,"type":34},"2026-06-30","ACTUAL",{"date":36,"type":21},"2026-07-01",{"date":38,"type":21},"2026-08-12",{"name":40,"class":41},"Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital","OTHER",{"id":43,"slug":44,"hasResults":11,"nctId":45,"briefTitle":46,"officialTitle":47,"acronym":4,"eligibilityCriteria":48,"healthyVolunteers":11,"sex":49,"minAge":18,"maxAge":50,"enrollmentInfo":51,"targetDuration":4,"studyType":53,"phases":4,"briefSummary":54,"conditions":55,"keywords":4,"overallStatus":59,"whyStopped":4,"lastUpdateSubmitDate":60,"lastUpdatePostDateStruct":61,"startDateStruct":63,"completionDateStruct":65,"leadSponsor":67,"locationsCount":68},"100635060","preoperative-sleep-quality-and-postoperative-outcomes-in-breast-surgery-100635060","NCT07547774","Preoperative Sleep Quality and Postoperative Outcomes in Breast Surgery","Role of Preoperative Sleep Quality in Predicting Postoperative Inflammation, Pain Severity, and Analgesic Requirement After Breast Cancer Surgery","Inclusion Criteria:\n\n* Female patients aged 18 to 70 years\n* Scheduled for elective breast cancer surgery\n* American Society of Anesthesiologists (ASA) physical status I to III\n* Able to understand and complete the Pittsburgh Sleep Quality Index (PSQI)\n* Willing to participate in the study\n* Provided written informed consent\n\nExclusion Criteria:\n\n* Active infection\n* History of chronic inflammatory disease or autoimmune disease\n* Use of steroids or immunosuppressive drugs within the past 6 months\n* Known diagnosis of obstructive sleep apnea syndrome\n* Severe cognitive impairment preventing completion of the questionnaire\n* Planned emergency surgery\n* Refusal to participate or failure to provide informed consent","FEMALE","70 Years",{"count":52,"type":21},150,"OBSERVATIONAL","Sleep quality is a key physiological factor influencing immune function, inflammatory response, and pain perception. This prospective observational study aims to evaluate whether preoperative sleep quality predicts postoperative inflammation, pain severity, and analgesic consumption in patients undergoing elective breast cancer surgery.\n\nPreoperative sleep quality will be assessed using the Pittsburgh Sleep Quality Index (PSQI). Systemic inflammatory response will be evaluated using the Systemic Immune-Inflammation Index (SII), calculated from routine hematological parameters. Postoperative pain will be assessed using the Visual Analog Scale (VAS), and analgesic consumption will be recorded within the first 24 hours.\n\nThe study aims to determine whether poor sleep quality is associated with increased inflammatory response, higher pain scores, and greater analgesic requirement.",[56,57,58],"Breast Cancer","Postoperative Pain","Inflammation","RECRUITING","2026-04-26",{"date":62,"type":34},"2026-04-30",{"date":64,"type":34},"2026-04-01",{"date":66,"type":21},"2026-07-15",{"name":40,"class":41},1,{"id":70,"slug":71,"hasResults":11,"nctId":72,"briefTitle":73,"officialTitle":74,"acronym":4,"eligibilityCriteria":75,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":76,"targetDuration":4,"studyType":53,"phases":4,"briefSummary":78,"conditions":79,"keywords":4,"overallStatus":59,"whyStopped":4,"lastUpdateSubmitDate":60,"lastUpdatePostDateStruct":82,"startDateStruct":83,"completionDateStruct":85,"leadSponsor":87,"locationsCount":68},"100635048","analgesic-consumption-in-the-early-postoperative-period-a-prospective-observational-pacu-study-100635048","NCT07547618","Analgesic Consumption in the Early Postoperative Period: A Prospective Observational PACU Study","Factors Influencing Analgesic Consumption in the Early Postoperative Period: A Prospective Observational Study in the Post-Anesthesia Care Unit","Inclusion Criteria:\n\n* Adults aged 18 years and older\n* Undergoing elective surgical procedures\n* Admitted to the post-anesthesia care unit (PACU) after surgery\n* Receiving general and\u002For regional anesthesia\n* Able to provide informed consent\n\nExclusion Criteria:\n\n* Patients younger than 18 years\n* Emergency surgical procedures\n* Patients transferred directly to the intensive care unit postoperatively\n* PACU stay shorter than 30 minutes\n* Patients unable to communicate or assess pain\n* Incomplete clinical records\n* Refusal to participate in the study",{"count":77,"type":21},254,"Postoperative pain remains a significant clinical challenge that directly affects patient recovery, functional outcomes, and overall quality of care. Inadequate pain control in the early postoperative period is associated with delayed mobilization, increased risk of complications, prolonged hospital stay, and the development of chronic pain. The post-anesthesia care unit (PACU) represents a critical phase in which pain is actively assessed and managed, and analgesic consumption during this period serves as an objective indicator of analgesic requirements and effectiveness of perioperative pain strategies.\n\nThis prospective observational study aims to identify patient-related, surgical, and anesthesia-related factors influencing analgesic consumption in the early postoperative period among adult patients admitted to the PACU following elective surgery. No additional interventions will be performed, and all perioperative management will follow routine clinical practice. Data will be collected prospectively from clinical records, anesthesia charts, and PACU monitoring forms.\n\nThe primary outcome is total analgesic consumption during the PACU stay. Secondary outcomes include pain intensity assessed using a standardized pain scale at PACU admission and discharge, requirement for rescue analgesia, incidence of postoperative nausea and vomiting, and length of stay in the PACU.\n\nThe findings of this study are expected to contribute to the identification of patients at higher risk for increased analgesic requirements and to support the development of individualized pain management strategies, ultimately improving perioperative care quality and patient outcomes.",[57,80,81],"Analgesic Consumption","Pain Management",{"date":62,"type":34},{"date":84,"type":34},"2026-04-05",{"date":86,"type":21},"2026-07-20",{"name":40,"class":41},{"id":89,"slug":90,"hasResults":11,"nctId":91,"briefTitle":92,"officialTitle":93,"acronym":94,"eligibilityCriteria":95,"healthyVolunteers":11,"sex":17,"minAge":96,"maxAge":4,"enrollmentInfo":97,"targetDuration":4,"studyType":53,"phases":4,"briefSummary":99,"conditions":100,"keywords":4,"overallStatus":59,"whyStopped":4,"lastUpdateSubmitDate":104,"lastUpdatePostDateStruct":105,"startDateStruct":106,"completionDateStruct":108,"leadSponsor":110,"locationsCount":68},"100623298","can-ultrasound-guided-fascial-plane-blocks-reduce-postoperative-pulmonary-complications-after-major-abdominal-surgery-100623298","NCT07394816","Can Ultrasound-Guided Fascial Plane Blocks Reduce Postoperative Pulmonary Complications After Major Abdominal Surgery?","The Effect of Ultrasound-Guided Fascial Plane Blocks on Postoperative Pulmonary Complications in Patients Undergoing Major Abdominal Surgery: A Prospective Observational Study","FPB-PPC","Inclusion Criteria:\n\n* Age 65 years or older\n* Scheduled for elective major abdominal surgery (e.g., colorectal, hepatobiliary, pancreatic, or gastric surgery)\n* ASA physical status II-III\n* Ability to provide written informed consent\n* Planned use of general anesthesia with or without adjunct regional techniques\n\nExclusion Criteria:\n\n* Refusal or inability to provide informed consent\n* Known allergy or contraindication to local anesthetics\n* Coagulopathy or ongoing anticoagulant therapy contraindicating regional anesthesia\n* Infection at the site of planned block\n* Pre-existing chronic opioid use or chronic pain syndrome\n* Severe hepatic, renal, or cardiac failure (e.g., Child-Pugh C, end-stage renal disease, EF \\\u003C30%)\n* Cognitive impairment or severe dementia preventing adequate pain assessment\n* Emergency surgery\n* Body mass index (BMI \\> 40 kg\u002Fm²)","65 Years",{"count":98,"type":21},500,"This prospective observational study aims to evaluate whether the use of ultrasound-guided fascial plane blocks is associated with a lower incidence of postoperative pulmonary complications in adult patients undergoing elective major abdominal surgery under general anesthesia.\n\nPatients will be observed in two groups based on routine clinical practice: those who receive an ultrasound-guided fascial plane block for postoperative analgesia and those managed with other standard analgesic methods. The choice of analgesic technique will be determined by the responsible anesthesia team and not influenced by the study.\n\nPostoperative pulmonary complications occurring within the first 7 days after surgery will be recorded using reopening the European Perioperative Clinical Outcome (EPCO) criteria. Secondary outcomes will include unplanned intensive care unit admission, length of hospital stay, and 30-day mortality. No additional procedures or interventions will be performed for research purposes.",[101,102,103],"Postoperative Pulmonary Complications (PPCs)","Abdominal Surgeries","Postoperative Pain Management","2026-04-25",{"date":62,"type":34},{"date":107,"type":34},"2026-03-01",{"date":109,"type":21},"2026-08-15",{"name":40,"class":41},{"id":112,"slug":113,"hasResults":11,"nctId":114,"briefTitle":115,"officialTitle":116,"acronym":4,"eligibilityCriteria":117,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":118,"targetDuration":4,"studyType":53,"phases":4,"briefSummary":119,"conditions":120,"keywords":4,"overallStatus":59,"whyStopped":4,"lastUpdateSubmitDate":125,"lastUpdatePostDateStruct":126,"startDateStruct":128,"completionDateStruct":130,"leadSponsor":132,"locationsCount":68},"100634687","prediction-of-postoperative-icu-requirement-in-oncologic-surgery-100634687","NCT07542925","Prediction of Postoperative ICU Requirement in Oncologic Surgery","Comparison of ASA, SORT, CACI, and P-POSSUM Scores for Predicting Postoperative Intensive Care Unit Requirement in Patients Undergoing Oncologic Surgery","Inclusion Criteria:\n\n* Patients aged 18 years and older.\n* Patients scheduled for elective or emergency oncologic surgery.\n* Patients who are able to provide written informed consent.\n* Patients whose data will be analyzed for both planned and unplanned intensive care unit (ICU) admissions.\n\nExclusion Criteria:\n\n* Patients under 18 years of age.\n* Patients requiring continuous ICU follow-up due to a pre-existing critical illness prior to the current surgery.\n* Patients who do not provide consent to participate in the study.",{"count":98,"type":21},"This prospective observational cohort study aims to compare the performance of commonly used perioperative risk scoring systems in predicting postoperative intensive care unit (ICU) requirement among adult patients undergoing oncologic surgery. Accurate prediction of postoperative ICU admission is essential for optimizing patient safety and efficient allocation of limited critical care resources, particularly in high-risk oncologic surgical populations.\n\nA total of 500 adult patients scheduled for elective or emergency oncologic surgery will be prospectively enrolled at a single tertiary oncology center. Preoperative clinical and demographic data, intraoperative variables, and perioperative characteristics will be recorded using a standardized data collection form. Risk assessment will include the American Society of Anesthesiologists (ASA) Physical Status classification, Surgical Outcome Risk Tool (SORT), Age-adjusted Charlson Comorbidity Index (CACI), Portsmouth Physiological and Operative Severity Score for the enumeration of Mortality and morbidity (P-POSSUM), Eastern Cooperative Oncology Group (ECOG) performance status, Nutritional Risk Screening 2002 (NRS-2002), and preoperative serum albumin levels.\n\nThe primary outcome is the need for postoperative ICU admission within the first 24 hours after surgery. Secondary outcomes include unplanned ICU admission, duration of ICU stay, need for mechanical ventilation, hospital length of stay, and 30-day mortality. The predictive performance of each scoring system will be evaluated using receiver operating characteristic (ROC) analysis and multivariable logistic regression models.",[121,122,123,124],"Neoplasms","Postoperative Complications","Perioperative\u002FPostoperative Complications","Intensive Care Units","2026-04-18",{"date":127,"type":34},"2026-04-21",{"date":129,"type":34},"2025-12-15",{"date":131,"type":21},"2026-11-15",{"name":40,"class":41},{"id":134,"slug":135,"hasResults":11,"nctId":136,"briefTitle":137,"officialTitle":137,"acronym":4,"eligibilityCriteria":138,"healthyVolunteers":11,"sex":49,"minAge":18,"maxAge":139,"enrollmentInfo":140,"targetDuration":4,"studyType":53,"phases":4,"briefSummary":142,"conditions":143,"keywords":4,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":146,"lastUpdatePostDateStruct":147,"startDateStruct":149,"completionDateStruct":150,"leadSponsor":152,"locationsCount":4},"100634454","the-role-of-preoperative-internal-jugular-vein-collapsibility-and-perfusion-index-in-predicting-hypotension-after-spinal-anesthesia-in-elective-cesarean-sections-a-prospective-observational-study-100634454","NCT07539896","The Role of Preoperative Internal Jugular Vein Collapsibility and Perfusion Index in Predicting Hypotension After Spinal Anesthesia in Elective Cesarean Sections: A Prospective Observational Study","Inclusion Criteria:\n\nAge 18-45 years Singleton pregnancy Scheduled for elective cesarean section Planned spinal anesthesia ASA physical status II\n\nExclusion Criteria:\n\nHypertensive disorders of pregnancy (e.g., preeclampsia, HELLP syndrome) Known significant cardiac disease or pulmonary hypertension Chronic kidney disease Hemoglobinopathies Multiple pregnancy Emergency cesarean section Conversion to general anesthesia Anatomical or pathological conditions preventing IJV ultrasound assessment -","45 Years",{"count":141,"type":21},110,"Spinal anesthesia is widely preferred for elective cesarean delivery due to its favorable safety profile and superior postoperative analgesia. However, post-spinal hypotension (PSH) remains a common complication, with reported incidence rates ranging from 40% to 70%, potentially compromising maternal hemodynamic stability and uteroplacental perfusion. Early identification of patients at high risk for PSH is therefore of critical clinical importance.\n\nThis prospective observational study aims to evaluate the predictive performance of preoperative internal jugular vein collapsibility index (IJV-CI), assessed by ultrasonography, and baseline perfusion index (PI), obtained via pulse oximetry, for the development of PSH in patients undergoing elective cesarean section under spinal anesthesia. While IJV-CI reflects intravascular volume status and preload, PI represents peripheral vascular tone; thus, their combined use may improve predictive accuracy.\n\nStudy Design This is a single-center, prospective observational study conducted in patients scheduled for elective cesarean delivery under spinal anesthesia. No additional intervention will be applied, and all anesthetic management will follow standard clinical practice.\n\nObjectives\n\nPrimary Objective:\n\nTo assess the ability of preoperative IJV collapsibility index (IJV-CI) and baseline perfusion index (PI) to predict post-spinal hypotension.\n\nSecondary Objectives:\n\nTo evaluate the relationship between IJV-CI and PI with:\n\nDuration and number of hypotensive episodes Minimum systolic and mean arterial pressure Total vasopressor requirement Incidence of intraoperative nausea and vomiting Pregnant women aged 18-45 years, ASA II, with singleton pregnancies scheduled for elective cesarean section under spinal anesthesia.\n\nInclusion Criteria Age 18-45 years Elective cesarean section Planned spinal anesthesia ASA physical status II Singleton pregnancy Exclusion Criteria Hypertensive disorders of pregnancy (e.g., preeclampsia, HELLP) Significant cardiac or pulmonary disease Chronic kidney disease Multiple pregnancy Emergency cesarean delivery Conversion to general anesthesia\n\nConditions preventing IJV ultrasonographic assessmentBaseline PI will be recorded preoperatively using standard pulse oximetry. IJV diameters will be measured via ultrasound, and the collapsibility index will be calculated as:\n\nIJVI: (Dmax-Dmin\u002FDmax)X100 Hemodynamic parameters will be recorded at 3-minute intervals from spinal anesthesia administration until delivery. Statistical analysis will include ROC curve analysis, correlation analysis, and logistic regression to evaluate predictive performance.",[144,145],"Postspinal Hypotension","Cesarean Birth","2026-04-14",{"date":148,"type":34},"2026-04-20",{"date":104,"type":21},{"date":151,"type":21},"2026-06-25",{"name":40,"class":41},{"id":154,"slug":155,"hasResults":11,"nctId":156,"briefTitle":157,"officialTitle":158,"acronym":4,"eligibilityCriteria":159,"healthyVolunteers":11,"sex":17,"minAge":96,"maxAge":4,"enrollmentInfo":160,"targetDuration":4,"studyType":53,"phases":4,"briefSummary":162,"conditions":163,"keywords":4,"overallStatus":59,"whyStopped":4,"lastUpdateSubmitDate":168,"lastUpdatePostDateStruct":169,"startDateStruct":171,"completionDateStruct":173,"leadSponsor":175,"locationsCount":68},"100629990","skin-conductance-for-predicting-spinal-anesthesia-induced-hypotension-in-geriatric-urologic-oncology-patients-100629990","NCT07481851","Skin Conductance for Predicting Spinal Anesthesia-Induced Hypotension in Geriatric Urologic Oncology Patients","Skin Conductance as a Predictor of Spinal Anesthesia-Induced Hypotension in Geriatric Oncology Patients","Inclusion Criteria:\n\n* Patients aged 65 years and older\n* Patients scheduled for elective urologic oncology surgery under spinal anesthesia\n* American Society of Anesthesiologists (ASA) physical status I-III\n* Patients who provide written informed consent to participate in the study\n\nExclusion Criteria:\n\n* Refusal to participate or inability to provide informed consent\n* Contraindication to spinal anesthesia (e.g., infection at puncture site, coagulopathy)\n* Severe cardiac conduction abnormalities or presence of a cardiac pacemaker\n* Severe autonomic dysfunction or known neuropathy affecting autonomic responses\n* Use of medications that significantly affect autonomic nervous system activity\n* Baseline hypotension or hemodynamic instability before spinal anesthesia\n* Inability to obtain reliable skin conductance measurements (e.g., severe skin lesions at electrode placement site)",{"count":161,"type":21},102,"Spinal anesthesia-induced hypotension is a common and clinically significant complication in elderly patients undergoing oncologic surgery. Early identification of patients at risk for hemodynamic instability remains a major challenge in perioperative management. Skin conductance reflects sympathetic nervous system activity and may provide a noninvasive indicator of autonomic responses. This prospective observational study aims to evaluate whether skin conductance measurements can predict the development of hypotension following spinal anesthesia in geriatric oncology patients undergoing urologic surgery. The findings may contribute to improved perioperative monitoring and early risk stratification in this vulnerable patient population.",[164,165,166,167],"Hypotension","Urologic Neoplasms","Aged","Spinal Anesthesia","2026-03-23",{"date":170,"type":34},"2026-03-25",{"date":172,"type":34},"2025-12-22",{"date":174,"type":21},"2026-05-01",{"name":40,"class":41},{"id":177,"slug":178,"hasResults":11,"nctId":179,"briefTitle":180,"officialTitle":181,"acronym":4,"eligibilityCriteria":182,"healthyVolunteers":11,"sex":17,"minAge":183,"maxAge":4,"enrollmentInfo":184,"targetDuration":4,"studyType":53,"phases":4,"briefSummary":186,"conditions":187,"keywords":190,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":198,"lastUpdatePostDateStruct":199,"startDateStruct":201,"completionDateStruct":203,"leadSponsor":205,"locationsCount":4},"100628426","effect-of-visual-aids-added-to-informed-consent-on-patient-understanding-and-anesthesia-awareness-100628426","NCT07461480","Effect of Visual Aids Added to Informed Consent on Patient Understanding and Anesthesia Awareness","The Effect of Visual Aids Used in Addition to the Informed Consent Form on Understanding of Consent and Level of Anesthesia Awareness in Patients Attending the Anesthesia Outpatient Clinic","Inclusion Criteria:\n\n* Age ≥ 18 years\n* Patients presenting to the anesthesia outpatient clinic for preoperative -evaluation\n* Scheduled for elective surgery requiring anesthesia\n* Able to read and understand Turkish\n* Able to provide informed consent\n* Willing to participate in the study\n\nExclusion Criteria:\n\n* Age under 18 years\n* Emergency surgery cases\n* Known cognitive impairment or diagnosed psychiatric disorder affecting comprehension\n* Visual or hearing impairment preventing adequate communication Illiteracy\n* Previous participation in this study\n* Refusal to participate","18 Months",{"count":185,"type":21},236,"This prospective cluster-randomized controlled study aims to evaluate whether visual support material provided in addition to the standard written informed consent form improves patients' comprehension of informed consent and their level of anesthesia awareness in an anesthesia outpatient clinic setting.\n\nPatients presenting to the anesthesia outpatient clinic will be allocated in clusters to receive either standard written informed consent alone or standard consent supplemented with structured visual support material. All patients will receive standardized verbal information delivered by the same anesthesiologist.\n\nThirty minutes after the information session, comprehension of informed consent and anesthesia awareness levels will be assessed using a structured questionnaire administered in a standardized manner by a blinded anesthesiologist.\n\nThe primary objective is to determine whether visual support enhances patient understanding of informed consent. Secondary objectives include evaluating its effect on anesthesia-related risk awareness and overall anesthesia knowledge.",[188,189],"Anesthesia","Surgical Patients",[191,192,193,194,195,196,197],"Informed Consent","Visual Support","Health Communication","Cluster Randomized Trial","Anesthesia Outpatient Clinic","Risk Awareness","Patient Education","2026-03-13",{"date":200,"type":34},"2026-03-17",{"date":202,"type":21},"2026-03",{"date":204,"type":21},"2026-11",{"name":40,"class":41},{"id":207,"slug":208,"hasResults":11,"nctId":209,"briefTitle":210,"officialTitle":211,"acronym":212,"eligibilityCriteria":213,"healthyVolunteers":16,"sex":17,"minAge":96,"maxAge":4,"enrollmentInfo":214,"targetDuration":4,"studyType":53,"phases":4,"briefSummary":216,"conditions":217,"keywords":222,"overallStatus":59,"whyStopped":4,"lastUpdateSubmitDate":226,"lastUpdatePostDateStruct":227,"startDateStruct":229,"completionDateStruct":231,"leadSponsor":233,"locationsCount":68},"100624567","internal-jugular-vein-ultrasound-for-predicting-hypotension-in-geriatric-patients-undergoing-spinal-anesthesia-100624567","NCT07411313","Internal Jugular Vein Ultrasound for Predicting Hypotension in Geriatric Patients Undergoing Spinal Anesthesia","The Role of Internal Jugular Vein Ultrasonography in Predicting Hypotension in Geriatric Patients Undergoing Spinal Anesthesia: A Prospective Observational Study (Protocol ID: 2023-12\u002F509)","IJV-SPINAL","Inclusion Criteria:\n\n* Age ≥65 years\n* Scheduled to undergo surgery under spinal anesthesia\n* American Society of Anesthesiologists (ASA) physical status I-III\n* Able and willing to provide written informed consent\n\nExclusion Criteria:\n\n* Did not provide written informed consent\n* Undergoing emergency surgery\n* Body mass index (BMI) ≥40 kg\u002Fm²\n* Receiving angiotensin-converting enzyme (ACE) inhibitors\n* Pre-spinal systolic blood pressure \\\u003C90 mmHg or mean arterial pressure \\\u003C70 mmHg\n* Unable to tolerate the supine position\n* Left ventricular ejection fraction \\\u003C40%\n* Requiring sedoanalgesia in addition to spinal anesthesia or conversion to general anesthesia",{"count":215,"type":21},85,"Spinal anesthesia-induced hypotension is a common and clinically significant complication in geriatric patients. Accurate preoperative assessment of intravascular volume status may help identify patients at risk. Internal jugular vein (IJV) ultrasonography is a noninvasive and easily applicable bedside method that reflects venous volume status. This prospective observational study aims to evaluate the role of preoperative IJV ultrasonographic measurements in predicting hypotension following spinal anesthesia in geriatric patients. Patients aged 65 years and older undergoing elective surgery under spinal anesthesia will be included. Preoperative IJV diameter, cross-sectional area, and collapsibility index will be measured using ultrasonography. Hemodynamic parameters will be monitored intraoperatively, and the occurrence of hypotension after spinal anesthesia will be recorded. The predictive value of IJV ultrasonographic parameters for post-spinal hypotension will be analyzed",[218,219,220,221],"Spinal Anesthesia Induced Hypotension","Geriatric","Internal Jugular Vein","Ultrasonography",[223,224,164,221,225],"Geriatric patients","Spinal anesthesia","Internal jugular vein","2026-02-11",{"date":228,"type":34},"2026-02-13",{"date":230,"type":34},"2024-01-03",{"date":232,"type":21},"2026-02-10",{"name":40,"class":41},{"id":235,"slug":236,"hasResults":11,"nctId":237,"briefTitle":238,"officialTitle":239,"acronym":4,"eligibilityCriteria":240,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":241,"enrollmentInfo":242,"targetDuration":4,"studyType":22,"phases":244,"briefSummary":245,"conditions":246,"keywords":248,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":251,"lastUpdatePostDateStruct":252,"startDateStruct":254,"completionDateStruct":256,"leadSponsor":258,"locationsCount":4},"100622735","effect-of-patient-position-on-erector-spinae-plane-block-in-thoracic-surgery-100622735","NCT07387484","Effect of Patient Position on Erector Spinae Plane Block in Thoracic Surgery","Effect of Patient Position on Dermatomal Spread and Analgesic Outcomes of Erector Spinae Plane Block in Thoracic Surgery: A Prospective Randomized Clinical Trial","Inclusion Criteria:\n\n* Age 18 to 75 years\n* ASA physical status II-IV\n* Scheduled for elective video-assisted thoracic surgery\n* Ability to provide written informed consent\n\nExclusion Criteria:\n\n* Known allergy to local anesthetics\n* Chronic opioid use\n* Preexisting chronic pain\n* Severe cognitive impairment\n* Technical difficulty with positioning\n* Emergency surgery\n* Refusal to participate","75 Years",{"count":243,"type":21},90,[24],"The erector spinae plane (ESP) block is a widely used regional anesthesia technique for postoperative analgesia in thoracic surgery. The block can be performed in different patient positions, most commonly sitting or lateral decubitus, but the effect of patient position on dermatomal sensory spread and analgesic efficacy has not been clearly established.\n\nThis prospective, randomized, single-blind clinical trial aims to compare the effects of ESP block performed in sitting versus lateral decubitus position on dermatomal sensory distribution and postoperative analgesic outcomes in patients undergoing video-assisted thoracic surgery.",[247,57],"Thoracic Surgery, Video Assisted",[249,250],"video assisted thorachoscopic surgery","erector spinae plane block","2026-02-04",{"date":253,"type":34},"2026-02-06",{"date":255,"type":21},"2026-02",{"date":257,"type":21},"2026-05",{"name":40,"class":41},{"id":260,"slug":261,"hasResults":11,"nctId":262,"briefTitle":263,"officialTitle":264,"acronym":265,"eligibilityCriteria":266,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":267,"enrollmentInfo":268,"targetDuration":270,"studyType":53,"phases":4,"briefSummary":271,"conditions":272,"keywords":276,"overallStatus":59,"whyStopped":4,"lastUpdateSubmitDate":281,"lastUpdatePostDateStruct":282,"startDateStruct":283,"completionDateStruct":285,"leadSponsor":287,"locationsCount":68},"100623088","comparison-of-fcv-and-vcv-in-one-lung-ventilation-100623088","NCT07392086","Comparison of FCV and VCV in One-Lung Ventilation","Comparison of the Effects of Flow-Controlled Ventilation (FCV) and Volume-Controlled Ventilation (VCV) on Respiratory Mechanics and Gas Exchange During One-Lung Ventilation: A Multicenter Prospective Observational Study (FCVOLVent)","FCVOLVent","Inclusion Criteria Adult patients aged 18 years and older Patients undergoing thoracic surgery requiring one-lung ventilation (OLV) Requirement for one-lung ventilation for at least 30 minutes American Society of Anesthesiologists (ASA) physical status I-III Provision of written informed consent Patients ventilated with flow-controlled ventilation (FCV) or volume-controlled ventilation (VCV) as part of routine clinical practice\n\nExclusion Criteria Requirement for emergency surgery History of untreated asthma High pulmonary risk, defined as predicted postoperative FEV₁ \\\u003C 20 mL\u002Fkg in males and \\\u003C 18 mL\u002Fkg in females High cardiac risk, including advanced cardiomyopathy with left ventricular ejection fraction \\\u003C 30% Body mass index (BMI) \\> 35 kg\u002Fm² Contraindication to total intravenous anesthesia (TIVA) Evidence of pulmonary infection prior to surgery Presence of other significant pulmonary pathologies (e.g., tuberculosis, bullous lung disease, bronchiectasis) Severe COPD (GOLD stage III-IV) or significant restrictive lung disease Age \\\u003C 18 years or \\> 80 years, or pregnancy ASA physical status IV or higher Uncontrolled arrhythmia or history of myocardial infarction within the past 3 months Inability to provide informed consent","80 Years",{"count":269,"type":21},60,"1 Year","One-lung ventilation (OLV) is commonly used during thoracic surgery but may negatively affect lung mechanics and gas exchange. Different ventilation strategies are used during OLV, and their effects on respiratory parameters remain an important clinical concern.\n\nFlow-controlled ventilation (FCV) is a newer ventilation mode that allows precise control of inspiratory and expiratory flow, potentially improving lung mechanics and gas exchange. Volume-controlled ventilation (VCV) is a widely used conventional ventilation strategy during thoracic anesthesia.\n\nThe FCVOLVent study is a multicenter, prospective observational study designed to compare the effects of FCV and VCV during one-lung ventilation in adult patients undergoing thoracic surgery. Patients will be ventilated with either FCV or VCV as part of routine clinical practice.\n\nThe study aims to evaluate respiratory mechanics and oxygenation parameters, including the PaO₂\u002FFiO₂ ratio, airway pressures, lung compliance, and mechanical power during surgery. Data will be collected at predefined time points during one-lung ventilation.\n\nThe results of this study are expected to provide real-world clinical evidence on the potential advantages and limitations of flow-controlled ventilation compared with volume-controlled ventilation during one-lung ventilation.",[273,274,275],"One-lung Ventilation (OLV)","Thoracic Surgery","Respiratory Mechanics",[277,278,279,280],"Flow-Controlled Ventilation","Thoracic Anesthesia","Volume-Controlled Ventilation","One-Lung Ventilation","2026-01-29",{"date":253,"type":34},{"date":284,"type":34},"2026-01-01",{"date":286,"type":21},"2026-12-01",{"name":40,"class":41},{"id":289,"slug":290,"hasResults":11,"nctId":291,"briefTitle":292,"officialTitle":293,"acronym":294,"eligibilityCriteria":295,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":296,"targetDuration":4,"studyType":53,"phases":4,"briefSummary":298,"conditions":299,"keywords":302,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":309,"lastUpdatePostDateStruct":310,"startDateStruct":312,"completionDateStruct":313,"leadSponsor":314,"locationsCount":68},"100617976","tracking-aillm-literacy-and-knowledge-in-urology-outpatients-talk-u-100617976","NCT07325617","Tracking AI\u002FLLM Literacy and Knowledge in Urology Outpatients (TALK-U)","The TALK-U Study: Tracking AI\u002FLLM Knowledge and Use in Urology Outpatients and Its Association With Anxiety, Satisfaction, and Health Awareness-A Cross-Sectional Study","TALK-U","Inclusion Criteria:\n\n* Age 18 years or older\n* First-time visit to the Urology Outpatient Clinic\n* Able to read and write and complete the questionnaire independently\n* Able to provide written informed consent\n\nExclusion Criteria:\n\n* Age under 18 years\n* Insufficient literacy to understand and complete the questionnaire\n* Severe hearing or visual impairment, or a neurological\u002Fpsychiatric condition that prevents understanding and completing the survey\n* Refusal or inability to provide informed consent\n* Currently under follow-up for a known urologic condition (i.e., not a first-time urology outpatient visit)",{"count":297,"type":21},400,"This study is a one-time, questionnaire-based survey of adults attending a urology outpatient clinic. The investigators will examine whether patients who use AI chat tools based on large language models (LLMs), such as ChatGPT, before seeking care differ from non-users in (1) anxiety, (2) satisfaction with the clinic visit, and (3) awareness\u002Funderstanding of their health condition.\n\nParticipants who provide written informed consent will complete a brief survey during their clinic visit (about 5-7 minutes). The survey includes a standardized anxiety scale (GAD-7), visual analog scales (0-10) for anxiety before and after the visit, satisfaction, and disease awareness, as well as questions about AI\u002FLLM knowledge and use. Treating clinicians will not have access to participants' survey responses, and participation will not affect clinical care.",[300,301],"Health Information Seeking Behavior","Anxiety",[303,301,304,305,306,307,308],"Artificial intelligence","ChatGPT","Gemini","Health information seeking","Large language model (LLM)","Patient satisfaction","2026-01-08",{"date":311,"type":34},"2026-01-09",{"date":284,"type":21},{"date":107,"type":21},{"name":40,"class":41},{"id":316,"slug":317,"hasResults":11,"nctId":318,"briefTitle":319,"officialTitle":319,"acronym":4,"eligibilityCriteria":320,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":96,"enrollmentInfo":321,"targetDuration":4,"studyType":53,"phases":4,"briefSummary":322,"conditions":323,"keywords":326,"overallStatus":59,"whyStopped":4,"lastUpdateSubmitDate":329,"lastUpdatePostDateStruct":330,"startDateStruct":332,"completionDateStruct":334,"leadSponsor":336,"locationsCount":68},"100615450","metabolomic-profiling-of-patients-with-traumatic-brain-injury-100615450","NCT07292766","Metabolomic Profiling of Patients With Traumatic Brain Injury","Inclusion Criteria:\n\n* Ages 18-65\n* Patients diagnosed with severe TBI clinically or according to National Institute for Health and Care Excellence (NICE) criteria (including post-traumatic imaging)\n* Patients with non-TBI orthopedic or multitrauma\n\nExclusion Criteria:\n\n* Presence of brain pathology in the pre-trauma period\n* Patient with chronic subdural hematoma",{"count":269,"type":21},"Traumatic Brain Injury (TBI) is a significant cause of mortality and morbidity worldwide. However, the literature on determining its severity and predicting prognosis is insufficient. This study aimed to examine the differences in metabolite levels between trauma patients with severe TBI and orthopedic trauma patients without brain injury.",[324,325],"Traumatic Brain Injury","Traumatic Brain Injury (TBI) Patients",[327,328],"traumatic brain injury","metabolomics","2025-12-17",{"date":331,"type":34},"2025-12-18",{"date":333,"type":34},"2024-02-01",{"date":335,"type":21},"2026-02-01",{"name":40,"class":41},{"id":338,"slug":339,"hasResults":11,"nctId":340,"briefTitle":341,"officialTitle":342,"acronym":4,"eligibilityCriteria":343,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":344,"enrollmentInfo":345,"targetDuration":4,"studyType":53,"phases":4,"briefSummary":347,"conditions":348,"keywords":353,"overallStatus":59,"whyStopped":4,"lastUpdateSubmitDate":356,"lastUpdatePostDateStruct":357,"startDateStruct":358,"completionDateStruct":360,"leadSponsor":361,"locationsCount":68},"100600697","the-effect-of-single-lung-ventilation-duration-on-postoperative-pulmonary-complications-in-thoracic-surgery-100600697","NCT07100860","The Effect of Single Lung Ventilation Duration on Postoperative Pulmonary Complications in Thoracic Surgery","Does Duration Matter? A Study on Single-Lung Ventilation Time and Pulmonary Complications in Thoracic Procedures","Inclusion Criteria:\n\nAge ≥18 years Undergoing thoracic surgery OLV planned during the procedure\n\nExclusion Criteria:\n\nPediatric patients Patients not requiring OLV Previous thoracic surgery","85 Years",{"count":346,"type":21},134,"This observational study investigates the relationship between the duration of single-lung ventilation (SLV) and the incidence of postoperative pulmonary complications (PPCs) such as pneumonia, pneumothorax, hemothorax, acute lung injury, and acute respiratory distress syndrome (ARDS) in adult patients undergoing thoracic surgery. A total of 134 patients aged 18-85 years, scheduled for thoracic surgery requiring SLV, will be monitored. Data including SLV duration, perioperative parameters, and postoperative pulmonary outcomes will be analyzed.",[349,350,351,352],"Postoperative Pulmonary Complications","One Lung Ventilation","Ards","Postoperative Pulmonary Atelectasis",[354,355],"postoperative pulmonary complications","one lung ventilation","2025-12-10",{"date":331,"type":34},{"date":359,"type":34},"2025-01-01",{"date":284,"type":21},{"name":40,"class":41},{"id":363,"slug":364,"hasResults":11,"nctId":365,"briefTitle":366,"officialTitle":367,"acronym":4,"eligibilityCriteria":368,"healthyVolunteers":16,"sex":49,"minAge":18,"maxAge":96,"enrollmentInfo":369,"targetDuration":4,"studyType":22,"phases":371,"briefSummary":372,"conditions":373,"keywords":374,"overallStatus":59,"whyStopped":4,"lastUpdateSubmitDate":377,"lastUpdatePostDateStruct":378,"startDateStruct":380,"completionDateStruct":382,"leadSponsor":384,"locationsCount":68},"100578982","the-effect-of-coconut-oil-on-alopecia-100578982","NCT06818370","The Effect of Coconut Oil on Alopecia","The Effect of Coconut Oil on Alopecia in Women Receiving Doxorubucin-Cycylophosphamide Treatment for Breast Cancer","Inclusion Criteria:\n\n* • To have been diagnosed with breast cancer.\n\n  * The chemotherapy treatment plan should be planned as the Doxorubicin-Cyclophosphamide protocol.\n  * Volunteer to participate in the study.\n  * Be 18 years of age or older.\n  * Being a woman.\n\nExclusion Criteria:\n\n* • Having any health problem or disability that prevents communication (vision-hearing problems, neurological, psychiatric diseases).\n\n  * Planning other treatments other than the Doxorubicin-Cyclophosphamide protocol for the treatment of breast cancer.\n  * Not volunteering to participate in the study.\n  * Having previously experienced any disease\u002Fskin problem that causes hair loss.\n  * Having received chemotherapy before.",{"count":370,"type":21},86,[24],"İn this study will be conducted to evaluate the effect of coconut oil on alopecia in 86 female breast cancer patients treated at Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital between 01.02.2025-31.12.2025.",[56],[375,56,376],"Alopecia","Coconut Oil","2025-02-08",{"date":379,"type":34},"2025-02-12",{"date":381,"type":34},"2025-02-03",{"date":383,"type":21},"2026-01-31",{"name":40,"class":41},""]