[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Dr. Mehak Naeem\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":74},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,41],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":23,"studyType":24,"phases":4,"briefSummary":25,"conditions":26,"keywords":4,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":29,"lastUpdatePostDateStruct":30,"startDateStruct":33,"completionDateStruct":35,"leadSponsor":37,"locationsCount":40},"100643518","how-trunk-control-links-autism-severity-to-functional-exercise-capacity-in-children-with-asd-100643518",false,"NCT07634107","How Trunk Control Links Autism Severity to Functional Exercise Capacity in Children With ASD","Trunk Control Mediates the Association Between Autism Severity and Functional Exercise Capacity in Children With Autism Spectrum Disorder","Inclusion Criteria:\n\n* Children aged 4-12 years (inclusive) at the time of assessment\n* Confirmed diagnosis of ASD according to DSM-5 criteria, documented in the hospital record by a licensed clinical psychologist or developmental paediatrician\n* Classified at DSM-5 severity Level 1, 2, or 3 in the existing clinical file\n* Currently attending physiotherapy or developmental rehabilitation outpatient services at the hospital\n* Able to attempt the Six-Minute Walk Test (6MWT) with or without verbal prompting\n* Written informed consent from parent or legal guardian; verbal assent from child where developmentally appropriate (aged 7 years and above)\n\nExclusion Criteria:\n\n* Co-existing neurological condition independently affecting gait (e.g., cerebral palsy, uncontrolled epilepsy)\n* Orthopaedic condition precluding walking or safe execution of the Trunk Impairment Scale\n* Acute illness, fever, or significant behavioural crisis at the time of the scheduled assessment session\n* Current enrolment in a structured physiotherapy or physical activity intervention programme\n* Caregiver refusal of consent or participant non-cooperation with either assessment tool at the time of the visit",true,"ALL","4 Years","12 Years",{"count":21,"type":22},200,"ESTIMATED","1 Day","OBSERVATIONAL","The goal of this observational study is to learn if trunk control (the ability to balance and stabilize the upper body while sitting or moving) links autism severity to functional exercise capacity in children aged 4-12 years with Autism Spectrum Disorder (ASD). The main questions it aims to answer are:\n\n1. Does trunk control explain why children with more severe ASD have lower functional exercise capacity?\n2. Do trunk control and functional exercise capacity differ across ASD severity levels (Level 1, 2, and 3)?\n\nParticipants will complete two assessments in a single 30-40 minute session during their routine clinic visit:\n\n1. A trunk control test, where a trained physiotherapist observes seated balance and movement.\n2. A 6-Minute Walk Test (6MWT), where the child moves along a flat hospital corridor for 6 minutes and the total distance covered is recorded as a measure of functional exercise capacity.\n\nNo treatment or intervention is involved. All assessments are safe, non-invasive, and conducted at a tertiary care children's hospital in Pakistan.",[27],"Autism Spectrum Disorder (ASD)","NOT_YET_RECRUITING","2026-06-06",{"date":31,"type":32},"2026-06-10","ACTUAL",{"date":34,"type":22},"2026-06",{"date":36,"type":22},"2026-07",{"name":38,"class":39},"Dr. Mehak Naeem","OTHER",1,{"id":42,"slug":43,"hasResults":11,"nctId":44,"briefTitle":45,"officialTitle":46,"acronym":4,"eligibilityCriteria":47,"healthyVolunteers":11,"sex":48,"minAge":49,"maxAge":50,"enrollmentInfo":51,"targetDuration":4,"studyType":53,"phases":54,"briefSummary":56,"conditions":57,"keywords":59,"overallStatus":65,"whyStopped":4,"lastUpdateSubmitDate":66,"lastUpdatePostDateStruct":67,"startDateStruct":69,"completionDateStruct":71,"leadSponsor":73,"locationsCount":40},"100638333","graded-motor-imagery-for-primary-dysmenorrhea-100638333","NCT07618832","Graded Motor Imagery for Primary Dysmenorrhea","Effect of Graded Motor Imagery on Pressure Pain Threshold and Pain Intensity in Women With Primary Dysmenorrhea: A Randomized Controlled Trial","Inclusion Criteria:\n\n1. Female sex (aged 18-30 years)\n2. Diagnosis of primary dysmenorrhea confirmed by a physician (painful menstruation for ≥6 consecutive cycles, in the absence of identifiable pelvic pathology on clinical and\u002For ultrasound evaluation)\n3. Pain ≥4\u002F10 NRS experienced during the last period.\n4. Confirmed altered pressure pain threshold: PPT ≥2 standard deviations below published norms for age-matched healthy women, measured at baseline assessment\n5. Regular menstrual cycle (21-35 days)\n6. Capable of engaging in virtual video sessions and taking online tests.\n7. Consent to withhold new analgesic or hormonal treatments during the study period.\n\nExclusion Criteria:\n\n1. Secondary dysmenorrhea (endometriosis, adenomyosis, fibroids, pelvic inflammatory disease, ovarian cysts ≥3 cm confirmed on imaging)\n2. Current use of hormonal contraceptives (which alter prostaglandin levels and pain processing)\n3. Pregnancy or lactation\n4. Concurrent chronic pain condition (fibromyalgia, CRPS, chronic low back pain, chronic pelvic pain unrelated to menstruation)\n5. Neurological or psychiatric disorder that would impair motor imagery ability (stroke, schizophrenia, active psychosis)\n6. Cognitive impairment affecting informed consent capacity\n7. Participation in another clinical trial within 4 weeks before enrollment\n8. Previous exposure to graded motor imagery or mirror therapy\n9. Regular use of NSAIDs or opioids for non-menstrual indications","FEMALE","18 Years","30 Years",{"count":52,"type":22},81,"INTERVENTIONAL",[55],"NA","The goal of this clinical trial is to learn if graded motor imagery can reduce pain sensitivity and period pain in women with primary dysmenorrhea (painful periods with no medical cause).\n\nThe main questions it aims to answer are:\n\n1. Is there a decrease in pressure pain threshold (increased pain sensitivity) with graded motor imagery?\n2. Is the intensity of menstrual pain reduced by graded motor imagery?\n3. Is GMI helpful to reduce menstrual symptoms and pain catastrophizing (negative thinking about pain)?\n\nResearchers will compare full GMI (active intervention), a sham GMI(inactive intervention), and a wait-list (no intervention) to see if GMI works better than the alternatives.\n\nParticipants will:\n\n1. Take part in a 6-week graded motor imagery program, sham program, or no intervention control.\n2. Do laterality recognition, motor imagery, and mirror therapy exercises in the graded motor imagery group.\n3. Complete pain and symptom assessments before and after the program, and again at follow-up.",[58],"Primary Dysmenorrhea (PD)",[60,61,62,63,64],"Graded Motor Imagery","Primary Dysmenorrhea","Primary dysmenorrhea and pressure pain threshold","Primary dysmenorrhea and altered pain sensitivity","Non-pharmacological intervention for primary dysmenorrhea","RECRUITING","2026-05-30",{"date":68,"type":32},"2026-06-02",{"date":70,"type":32},"2026-04-06",{"date":72,"type":22},"2026-08",{"name":38,"class":39},""]