[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Dr. Najat Khalifa\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":71},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,49],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":17,"sex":18,"minAge":19,"maxAge":20,"enrollmentInfo":21,"targetDuration":4,"studyType":24,"phases":25,"briefSummary":27,"conditions":28,"keywords":31,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":37,"lastUpdatePostDateStruct":38,"startDateStruct":41,"completionDateStruct":43,"leadSponsor":45,"locationsCount":48},"100353756","combined-anodal-transcranial-direct-current-stimulation-tdcs-and-cognitive-training-and-decision-making-100353756",false,"NCT03886025","Combined Anodal Transcranial Direct Current Stimulation (tDCS) and Cognitive Training and Decision-making","The Use of Combined Anodal Transcranial Direct Current Stimulation (tDCS) and Cognitive Training to Modulate Decision-making in Healthy People","tDCS-CTDM","Inclusion Criteria:\n\n* Consenting volunteers aged between 18 and 40.\n\nExclusion Criteria:\n\n* Individuals with epilepsy, other neurological conditions and history of significant head injury will be excluded.\n* Individuals with a history of substance misuse, major mental disorder and those receiving psychotropic medication will be also excluded.",true,"ALL","18 Years","40 Years",{"count":22,"type":23},60,"ESTIMATED","INTERVENTIONAL",[26],"NA","This study aims to (i) assess the effects of combined tDCS and cognitive training on decision-making on a trained task (Iowa Gambling Task; IGT); and (ii) test generalization to a closely related cognitive domain, namely motor impulsivity. It is hypothesized that combined anodal tDCS and cognitive training will result in more advantageous decisions and better impulse control than combined sham tDCS and cognitive training.",[29,30],"Impulsivity","Decision Making",[32,33,34,35],"transcranial Direct Current Stimulation (tDCS)","Decision-making","Implusivity","Brain stimulation","RECRUITING","2025-08-04",{"date":39,"type":40},"2025-08-08","ACTUAL",{"date":42,"type":40},"2022-09-15",{"date":44,"type":23},"2026-12-30",{"name":46,"class":47},"Dr. Najat Khalifa","OTHER",1,{"id":50,"slug":51,"hasResults":11,"nctId":52,"briefTitle":53,"officialTitle":54,"acronym":55,"eligibilityCriteria":56,"healthyVolunteers":11,"sex":18,"minAge":19,"maxAge":57,"enrollmentInfo":58,"targetDuration":4,"studyType":24,"phases":59,"briefSummary":60,"conditions":61,"keywords":4,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":63,"lastUpdatePostDateStruct":64,"startDateStruct":66,"completionDateStruct":68,"leadSponsor":70,"locationsCount":48},"100418694","the-use-of-transcranial-direct-current-stimulation-tdcs-in-adults-with-developmental-disabilities-100418694","NCT04732052","The Use of Transcranial Direct Current Stimulation (tDCS) in Adults With Developmental Disabilities","The Use of Transcranial Direct Current Stimulation (tDCS) to Reduce Impulsivity and Aggression in Adults With Developmental Disabilities: The tDCS-RIADD Randomized Controlled Trial Protocol","tDCS-RIADD","Inclusion Criteria:\n\n* Adults aged 18-64 years\n* Diagnosis of a developmental disability\n* History of one or more incidents of aggression in the last month\n* Consent to participate in the trial by the individual or their Substitute Decision Maker\n\nExclusion Criteria:\n\n* History of epilepsy or seizures\n* History of acquired brain injury\n* Having metal in the brain\u002Fskull, e.g. splinters, fragments or clips\n* Having a cochlear implant\n* Having an implanted neuro-stimulator (e.g. direct brain stimulation, epidural\u002Fsubdural stimulation, vagal nerve stimulation)\n* History of brain surgery of procedure\n* History of severe adverse reaction to tDCS\n* Having a cardiac pacemaker or intracardiac lines\n* Current alcohol or drug misuse\n* Having a sensitive scalp","65 Years",{"count":22,"type":23},[26],"Aggressive behaviours are highly prevalent among people with developmental disabilities, both in community and inpatient or residential settings, with adverse consequences for the individuals involved and others. Some predictive factors, particularly impulsivity, are dynamic with neurobiological underpinnings, and as such amenable to change or neuromodulation using non-invasive brain stimulation techniques. With this in mind, we designed an experimental protocol to determine the efficacy of transcranial Direct Current Stimulation (tDCS) as a non-invasive brain stimulation technique to reduce impulsivity and aggression associated with developmental disability.",[62],"Aggression","2025-03-21",{"date":65,"type":40},"2025-03-25",{"date":67,"type":40},"2022-09-01",{"date":69,"type":23},"2028-12-31",{"name":46,"class":47},""]