[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Dr. Ram Manohar Lohia Hospital\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":98},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,47,69],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":11,"sex":15,"minAge":16,"maxAge":17,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":30,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":35,"lastUpdatePostDateStruct":36,"startDateStruct":39,"completionDateStruct":41,"leadSponsor":43,"locationsCount":46},"100631128","phase-3-effect-of-anodal-transcranial-direct-current-stimulation-on-naming-in-aphasic-patients-with-acute-ischemic-stroke-100631128",false,"NCT07496645","EFFECT OF ANODAL TRANSCRANIAL DIRECT CURRENT STIMULATION ON NAMING IN APHASIC PATIENTS WITH ACUTE ISCHEMIC STROKE","Inclusion Criteria:\n\n* Aphasic patients with left middle cerebral artery territory Acute Ischemic Stroke\n* Patients between 18-65 years of age.\n* Within 5 days of onset of stroke.\n\nExclusion Criteria:\n\n* Patients with malignant Middle Cerebral Artery territory infarcts and previous clinical history of cerebral hemisphere stroke.\n* Patients with history of previous brain surgery or skull defect due to surgery e.g. craniectomy.\n* Patients with epilepsy.\n* Patients with history of significant head trauma in the last 1 month.\n* Patients with documented history of major depression prior to stroke.\n* Patients with alcohol\u002Fdrug abuse in the past 6 months.\n* Patients with prior significant cognitive impairment.\n* Pacemaker in situ, cochlear implant in situ.\n* Pregnancy.","ALL","18 Years","65 Years",{"count":19,"type":20},28,"ESTIMATED","INTERVENTIONAL",[23],"PHASE3","The use of transcranial direct current stimulation (tDCS) for the management of deficits developed in stroke is a relatively new type of management option. Many of the studies performed using tDCS have focused on improvements noted in hemiplegia as compared to aphasia, which is an equally disabling outcome of strokes. The results of these studies have not been conclusive and concordant with each other.\n\nIn aphasia management, the majority of the studies have focused on chronic strokes. Since the use of tDCS is relatively new, the studies have not focused on a particular type of deficit or stroke. Very few studies have focused on the impact of solely using tDCS. Very few studies have focused on acute to subacute strokes. The results of the studies have, nevertheless, been encouraging.\n\nImprovements in aspects of language tested after a single session of tDCS are short-lived. There is an unmet need to probe the utility of repetitive tDCS on aspects of language function in patients who are aphasic due to acute stroke. There is also a paucity of data in the Indian scenario regarding the same.",[26,27,28,29],"Acute Ischemic Cerebrovascular Disease","Post Stroke Aphasia","Aphasia Following Cerebral Infarction","Aphasia, Acquired",[31,32,26,33,28],"Transcranial Direct Current Stimulation","tDCS","Post stroke aphasia","NOT_YET_RECRUITING","2026-03-21",{"date":37,"type":38},"2026-03-27","ACTUAL",{"date":40,"type":20},"2026-03-31",{"date":42,"type":20},"2026-09-30",{"name":44,"class":45},"Dr. Ram Manohar Lohia Hospital","OTHER_GOV",1,{"id":48,"slug":49,"hasResults":11,"nctId":50,"briefTitle":51,"officialTitle":51,"acronym":4,"eligibilityCriteria":52,"healthyVolunteers":11,"sex":15,"minAge":4,"maxAge":4,"enrollmentInfo":53,"targetDuration":4,"studyType":21,"phases":55,"briefSummary":56,"conditions":57,"keywords":60,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":62,"lastUpdatePostDateStruct":63,"startDateStruct":65,"completionDateStruct":66,"leadSponsor":68,"locationsCount":46},"100623353","phase-3-effect-of-repetitive-bihemispheric-anodal-transcranial-direct-current-stimulation-on-motor-function-of-patients-with-parkinsons-disease-100623353","NCT07395531","Effect of Repetitive Bihemispheric Anodal Transcranial Direct Current Stimulation on Motor Function of Patients With Parkinson's Disease","Inclusion Criteria:\n\n1. Patients fulfilling the Movement Disorder Society (MDS) clinical diagnostic criteria for Parkinson's disease.\n2. Patients with Hoehn \\& Yahr stages 2-4 Parkinson's disease.\n3. Patients maintained on stable medical regimen for at least 1 month before entering the study.\n\nExclusion Criteria:\n\n1. Patients with other confounding neurological and psychiatric disorders.\n2. The presence of metal objects or stimulators in the head.\n3. Patients with a history of deep brain stimulation.\n4. Patients with history of seizures.\n5. Patients with skull defect due to surgery e.g. craniectomy\n6. Patients with scalp condition likely to obstruct application of electrodes.",{"count":54,"type":20},30,[23],"Dopaminergic medications and Deep Brain Stimulation (DBS) are the current standards interventions for Parkinson's Disease. Pharmacotherapy with dopaminergic drugs leads to partial improvement in motor functions of patients. Invasive therapies like DBS have as yet limited availability and accessibility, with risk of adverse events as well. Non invasive therapies like Transcranial Direct Current Stimulation (tDCS) are currently increasingly being probed for their therapeutic value, in view of their safety, portability and convenience of administration.\n\nImprovement in motor function immediately after a single session of tDCS has been observed. The effect of single simulation is not sustained beyond a few days. Only few studies with varied sites of stimulation have evaluated the effect of repetitive tDCS on motor function improvement in patients with Parkinson's Disease, with conflicting results. There is an unmet need to probe the utility of repetitive tDCS on motor function of patients with Parkinson's Disease.\n\nWe aim to probe the effect of repetitive tDCS of dorsolateral prefrontal cortex and M1 cortex on motor function in patients with Parkinson's Disease (Hoehn and Yahr stage 2 to 4).",[58,59],"PARKINSON DISEASE (Disorder)","Parkinson Disease",[32,61,31],"Parkinson's Disease","2026-02-01",{"date":64,"type":38},"2026-02-09",{"date":62,"type":20},{"date":67,"type":20},"2026-07-31",{"name":44,"class":45},{"id":70,"slug":71,"hasResults":11,"nctId":72,"briefTitle":73,"officialTitle":74,"acronym":75,"eligibilityCriteria":76,"healthyVolunteers":11,"sex":15,"minAge":16,"maxAge":4,"enrollmentInfo":77,"targetDuration":4,"studyType":79,"phases":4,"briefSummary":80,"conditions":81,"keywords":85,"overallStatus":89,"whyStopped":4,"lastUpdateSubmitDate":90,"lastUpdatePostDateStruct":91,"startDateStruct":93,"completionDateStruct":95,"leadSponsor":97,"locationsCount":46},"100605030","an-international-survey-on-the-use-of-niv-outside-the-icu-100605030","NCT07157215","An International Survey on the Use of NIV Outside the ICU","An International Survey on the Use of NIV Outside the ICU (NIV-Safety Study)","NIV-SAFETY","Inclusion criteria Physicians, Nursing Officers, and Respiratory therapists dealing with adult patients with acute and chronic respiratory failure.\n\nExclusion Criteria Physicians and Respiratory therapists who refuse to give consent.",{"count":78,"type":20},400,"OBSERVATIONAL","Non-invasive ventilation (NIV) is a way to support breathing using a mask or helmet instead of a breathing tube, and it is proven to reduce the need for intubation, save lives, shorten hospital stays, and lower costs. While NIV has long been used in intensive care units, it is now increasingly applied in emergency rooms, hospital wards, and long-term care facilities. However, global data on how it is used outside ICUs-such as which patients receive it, how well it works, and what barriers exist-is lacking. The NIV-Safety Study is a worldwide survey of doctors, nurses, and respiratory therapists to understand current practices, outcomes, and challenges of NIV use beyond the ICU. The findings aim to guide safer, more effective, and standardized use of NIV across different healthcare settings.",[82,83,84],"Non-invasive Ventilation","Intensive Care (ICU)","Safety",[86,87,88],"NIV","SAFETY","ICU","RECRUITING","2025-09-28",{"date":92,"type":38},"2025-09-30",{"date":94,"type":38},"2025-09-16",{"date":96,"type":20},"2026-03-15",{"name":44,"class":45},""]