[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"E-DA Hospital\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":123},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,4,0,[8,40,69,94],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":4,"overallStatus":27,"whyStopped":4,"lastUpdateSubmitDate":28,"lastUpdatePostDateStruct":29,"startDateStruct":32,"completionDateStruct":34,"leadSponsor":36,"locationsCount":39},"100505578","artificial-intelligence-assisted-colonoscopy-with-or-without-endocuff-vision-100505578",false,"NCT05863208","Artificial Intelligence-assisted Colonoscopy With or Without Endocuff Vision","Comparison of The Adenoma Detection Rate Between Artificial Intelligence-assisted Colonoscopy With or Without Endocuff Vision and Standard Colonscopy: A Randomized Controlled Study","Inclusion Criteria:\n\nPatients over 20 years old are undergoing outpatient sedative colonoscopy in the E-Da Hospital, E-Da cancer Hospital and Chung Shan Medical University Hospital in Taiwan\n\nExclusion Criteria:\n\n* A prior history of of inflammatory bowel disease, colorectal cancer, previous bowel resection, Peutz-Jeghers syndrome, familial adenomatous polyposis or other polyposis syndromes\n* Bleeding tendency\n* For scheduled endoscopic treatment","ALL","40 Years",{"count":19,"type":20},1000,"ESTIMATED","INTERVENTIONAL",[23],"NA","Adenoma detection rate (ADR) is considered the single most important quality measure in colonoscopy and a higher ADR can reduce the risk of interval colorectal cancer (CRC). Several kinds of new endoscopes and accessories have been accessed to investigate the abilities of improving the ADR. Artificial intelligence (AI) and Endocuff vision are promising new devices to improve the ADR. However, the effect of combining AI and Endocuff vision on ADR remains unclear. The aim of this prospective randomized study is to compare the ADR of AI plus Endocuff vision, AI alone and standard colonoscopy examination.",[26],"Adenoma Detection Rate","RECRUITING","2025-06-24",{"date":30,"type":31},"2025-06-27","ACTUAL",{"date":33,"type":31},"2023-05-02",{"date":35,"type":20},"2026-12-31",{"name":37,"class":38},"E-DA Hospital","OTHER",1,{"id":41,"slug":42,"hasResults":11,"nctId":43,"briefTitle":44,"officialTitle":45,"acronym":4,"eligibilityCriteria":46,"healthyVolunteers":11,"sex":16,"minAge":47,"maxAge":48,"enrollmentInfo":49,"targetDuration":4,"studyType":21,"phases":51,"briefSummary":52,"conditions":53,"keywords":56,"overallStatus":27,"whyStopped":4,"lastUpdateSubmitDate":61,"lastUpdatePostDateStruct":62,"startDateStruct":64,"completionDateStruct":66,"leadSponsor":67,"locationsCount":68},"100348072","a-feedback-enabled-magnetic-device-for-temporary-management-of-blepharoptosis-100348072","NCT03812016","A Feedback-enabled Magnetic Device for Temporary Management of Blepharoptosis","Comparison of Treatment Outcomes for Blepharoptosis of Various Etiologies Using a Feedback-enabled Magnetic Device","Inclusion Criteria:\n\n* Patients with ptosis; they are capable of understanding and complying with protocol requirements\n* Aged 18 years old or older\n\nExclusion Criteria:\n\n* Upper eyelid scar, contracture, or fibrosis due to previous surgical intervention(s)\n* Patients with psychiatric (or mental) disorders; they are unable to cooperate or follow the study procedure\n* Children younger than 18 years of age","18 Years","85 Years",{"count":50,"type":20},40,[23],"To develop a feedback-enabled magnetic device for management of blepharoptosis and evaluate its efficacy and safety, including the gain of palpebral fissure height, visual field obstruction, blurred vision, foreign body sensation over the cornea, burning or hot sensation over facial skin, and erythema or pruritus over the eyelid, by performing a human trial on patients with blepharoptosis.",[54,55],"Blepharoptosis","Device Usability",[54,57,58,59,60],"Blink restoration","Magnetic device","Oculomotor nerve palsy","Ptosis","2025-05-11",{"date":63,"type":31},"2025-05-14",{"date":65,"type":31},"2023-04-01",{"date":35,"type":20},{"name":37,"class":38},2,{"id":70,"slug":71,"hasResults":11,"nctId":72,"briefTitle":73,"officialTitle":74,"acronym":4,"eligibilityCriteria":75,"healthyVolunteers":11,"sex":16,"minAge":76,"maxAge":4,"enrollmentInfo":77,"targetDuration":4,"studyType":21,"phases":79,"briefSummary":80,"conditions":81,"keywords":84,"overallStatus":27,"whyStopped":4,"lastUpdateSubmitDate":87,"lastUpdatePostDateStruct":88,"startDateStruct":90,"completionDateStruct":92,"leadSponsor":93,"locationsCount":39},"100502116","the-prevalence-risk-factors-and-optimal-biopsy-protocol-of-be-100502116","NCT05818072","The Prevalence, Risk Factors and Optimal Biopsy Protocol of BE","The Prevalence, Risk Factors and Optimal Biopsy Protocol of Barrett's Esophagus in Taiwan - A Prospective Randomized Study","Inclusion Criteria:\n\n* Adults with columnar-lined esophagus\n\nExclusion Criteria:\n\n* A prior history of endoscopic treatment for Barrett's Esophagus\n* A prior history of upper gastrointestinal malignancy\n* A prior history of total or subtotal gastrectomy\n* Esophageal varices noted during the procedure\n* Uncontrolled coagulopathy\n* Taking antiplatelet drug or anticoagulant","20 Years",{"count":78,"type":20},165,[23],"Detections of goblet cells and dysplasia are crucial for diagnosis and determining the surveillance program of Barrett's esophagus (BE). However, the optimal biopsy numbers and their yield rates of intestinal metaplasia (IM) and dysplasia are still uncertain, especially in Asia. The aim of this study was to determine the optimal biopsy protocol of BE.",[82,83],"Barrett's Esophagus","Intestinal Metaplasia",[82,85,86],"Columnar-lined esophagus","Intestinal metaplasia","2023-05-09",{"date":89,"type":31},"2023-05-11",{"date":91,"type":31},"2023-03-13",{"date":35,"type":20},{"name":37,"class":38},{"id":95,"slug":96,"hasResults":11,"nctId":97,"briefTitle":98,"officialTitle":99,"acronym":4,"eligibilityCriteria":100,"healthyVolunteers":11,"sex":16,"minAge":76,"maxAge":101,"enrollmentInfo":102,"targetDuration":4,"studyType":21,"phases":104,"briefSummary":105,"conditions":106,"keywords":108,"overallStatus":27,"whyStopped":4,"lastUpdateSubmitDate":115,"lastUpdatePostDateStruct":116,"startDateStruct":118,"completionDateStruct":120,"leadSponsor":122,"locationsCount":39},"100299827","rfa-to-prevent-metachronous-squamous-neoplasia-recurrence-after-complete-endoscopic-submucosal-dissection-100299827","NCT03183115","RFA to Prevent Metachronous Squamous Neoplasia Recurrence After Complete Endoscopic Submucosal Dissection","Preemptive Radiofrequency Ablation for Esophageal Speckled Lugol Background Mucosa to Prevent Metachronous Neoplastic Recurrence After Complete Endoscopic Submucosal Dissection ~A Randomized Controlled Study","Inclusion Criteria:\n\n* Adults with early stage ESCNs (squamous high grade dysplasia, carcinoma in situ, or T1N0M0 SCC) who were treated by endoscopic submucosal dissection.\n* Lugol staining showed \"speckled\" (\\>10 small lugol-unstained lesions) pattern of background mucosa.\n\nExclusion Criteria:\n\n* Having a history of incomplete endoscopic treatment, or complications during\u002Fafter treatment (perforation, stricture).\n* Having history of systemic chemotherapy or radiation therapy for esophagus or post esophagectomy.\n* Life expectancy \\\u003C2 yr.\n* Decompensated cirrhosis (Child score B, C).\n* Having large esophageal varices.\n* Poor performance status (ECOG\\>2).","90 Years",{"count":103,"type":20},100,[23],"Esophageal cancer is a highly lethal disease, and its incidence is still increasing in the world. Recent advances in image-enhanced techniques such as Lugol chromoendoscopy and narrow band imaging, the number of patients with early esophageal squamous cell neoplasias (ESCNs) detected has markedly increased. Endoscopic submucosal dissection (ESD) enables en bloc resection of the neoplasia, and the resected specimen allows for a pathological assessment to evaluate the curability. However, the patients who received complete ESD for early ESCNs frequently developed metachronous recurrence. The cumulative metachronous recurrence rate at 5 years was 50%, and the mean annual incidence of newly diagnosed metachronous tumors was 10%. Among them, those with \"speckled\" lugol staining pattern over the esophageal background mucosa have the highest risk and should be seen as a precancerous lesion of ESCCs. This issue is gaining attention in the era of endoscopic treatment, but currently there was no appropriate strategy to prevent the tumor recurrence in these high-risk subjects.\n\nEndoscopic radiofrequency ablation (RFA) is a rapidly evolving therapeutic modality, and recent studies have shown its efficacy and safety for eradicating for flat type early ESCNs. To search a best strategy for the prevention of ESCNs, the investigators thus propose a hypothesis that the preemptive RFA for esophageal \"speckled\" lugol background mucosa may prevent the metachronous neoplastic recurrence after complete endoscopic resection.",[107],"Esophageal Squamous Cell Neoplasm",[109,110,111,112,113,114],"Early esophageal squamous cell neoplasm","Radiofrequency ablation","Endoscopic submucosal dissection","Esophageal cancer","Recurrence","Field cancerization","2023-03-02",{"date":117,"type":31},"2023-03-03",{"date":119,"type":31},"2016-04-18",{"date":121,"type":20},"2026-12-30",{"name":37,"class":38},""]