[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"EXACT Therapeutics AS\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":52},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":28,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":40,"lastUpdatePostDateStruct":41,"startDateStruct":44,"completionDateStruct":46,"leadSponsor":48,"locationsCount":51},"100581462","phase-2-acoustic-cluster-therapy-act-with-chemotherapy-for-the-treatment-of-locally-advanced-pancreatic-cancer-100581462",false,"NCT06850623","Acoustic Cluster Therapy (ACT) With Chemotherapy for the Treatment of Locally Advanced Pancreatic Cancer","A Phase 2 Study to Investigate the Efficacy and Safety of Acoustic Cluster Therapy With Modified FOLFIRINOX in Patients With Locally Advanced Pancreatic Cancer","ENACT","Inclusion Criteria:\n\n* Not deemed suitable for primary curative surgery and have radiographic and pathological disease consistent with inoperable LAPC or borderline resectable pancreatic cancer.\n* Suitable to receive treatment with mFOLFIRINOX according to the Investigator's assessment.\n\nExclusion Criteria:\n\n• Any prior anti-cancer treatment for pancreatic cancer (e.g. chemotherapy, surgery, radiation). Palliative bypass procedure and bile duct stenting are allowed.","ALL","18 Years",{"count":20,"type":21},25,"ESTIMATED","INTERVENTIONAL",[24],"PHASE2","The purpose of the study is to assess the efficacy and safety of Acoustic Cluster Therapy (ACT) when given in addition to chemotherapy for treatment of Locally Advanced Pancreatic Cancer.",[27],"Locally Advanced Pancreatic Adenocarcinoma",[29,30,31,32,33,34,35,36,37,38],"pancreatic cancer","PS101","ultrasound","microbubbles","Pancreatic Ductal Carcinoma","locally advanced pancreatic cancer","first line treatment","chemotherapy","Acoustic Cluster Therapy","mFOLFIRINOX","RECRUITING","2026-03-30",{"date":42,"type":43},"2026-04-03","ACTUAL",{"date":45,"type":43},"2025-06-19",{"date":47,"type":21},"2027-07-15",{"name":49,"class":50},"EXACT Therapeutics AS","INDUSTRY",10,""]